Fish Oil and Fenofibrate Prevented Phosphorylation-dependent Hepatic Sortilin 1 Degradation in Western Diet-fed Mice

The Hypercholesterolemia-Risk Gene SORT1 Facilitates PCSK9 Secretion

(2014) Camilla Gustafsen et al.   Cell Metabolism

Sortilin turnover is mediated by ubiquitination

(2013) Karine Dumaresq-Doiron et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosis

(2013) Roland Klingenberg et al.   JOURNAL OF CLINICAL INVESTIGATION

Saturated fatty acids activate ERK signaling to downregulate hepatic sortilin 1 in obese and diabetic mice

(2013) Lipeng Bi et al.   JOURNAL OF LIPID RESEARCH

Toll-Like Receptor 4 Deficiency Decreases Atherosclerosis But Does Not Protect Against Inflammation in Obese Low-Density Lipoprotein Receptor–Deficient Mice

(2012) Yilei Ding et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Saturated Fatty Acid and TLR Signaling Link β Cell Dysfunction and Islet Inflammation

(2012) Kosei Eguchi et al.   Cell Metabolism

PPARα as a therapeutic target in inflammation-associated diseases

(2012) Philippe Gervois et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

Hepatic sortilin regulates both apolipoprotein B secretion and LDL catabolism

(2012) Alanna Strong et al.   JOURNAL OF CLINICAL INVESTIGATION

Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice

(2012) Ding Ai et al.   JOURNAL OF CLINICAL INVESTIGATION

Dietary Combination of Fish Oil and Taurine Decreases Fat Accumulation and Ameliorates Blood Glucose Levels in Type 2 Diabetic/Obese KK-Ay Mice

(2012) Nana Mikami et al.   JOURNAL OF FOOD SCIENCE

Fish oil and indomethacin in combination potently reduce dyslipidemia and hepatic steatosis in LDLR−/−mice

(2012) Ganesan Murali et al.   JOURNAL OF LIPID RESEARCH

N-3 long-chain polyunsaturated fatty acids inhibit smooth muscle cell migration by modulating urokinase plasminogen activator receptor through MEK/ERK-dependent and -independent mechanisms

(2012) Claire Whyte et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The role of marine omega-3 (n-3) fatty acids in inflammatory processes, atherosclerosis and plaque stability

(2012) Philip C. Calder   MOLECULAR NUTRITION & FOOD RESEARCH

Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid–induced ceramide biosynthesis in mice

(2011) William L. Holland et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Fatty Liver Disease: Old Questions and New Insights

(2011) J. C. Cohen et al.   SCIENCE

Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance

(2011) Sung Hee Choi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Fish Oil for the Treatment of Cardiovascular Disease

(2010) Daniel Weitz et al.   Cardiology in Review

Sort1, Encoded by the Cardiovascular Risk Locus 1p13.3, Is a Regulator of Hepatic Lipoprotein Export

(2010) Mads Kjolby et al.   Cell Metabolism

The nutritional and clinical significance of lipid rafts

(2010) Parveen Yaqoob et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Transgenic expression of cholesterol 7α-hydroxylase in the liver prevents high-fat diet-induced obesity and insulin resistance in mice

(2010) Tiangang Li et al.   HEPATOLOGY

Free fatty acid metabolic profile and biomarkers of isolated post-challenge diabetes and type 2 diabetes mellitus based on GC–MS and multivariate statistical analysis

(2010) Liyan Liu et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Mechanisms underlying the cardioprotective effects of omega-3 polyunsaturated fatty acids

(2010) Yuriko Adkins et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

(2010) Kiran Musunuru et al.   NATURE

Genetic variation at chromosome 1p13.3 affects sortilin mRNA expression, cellular LDL-uptake and serum LDL levels which translates to the risk of coronary artery disease

(2009) Patrick Linsel-Nitschke et al.   ATHEROSCLEROSIS

The Vps10p-domain receptor family

(2009) Guido Hermey   CELLULAR AND MOLECULAR LIFE SCIENCES

Prevention of insulin resistance by n-3 polyunsaturated fatty acids

(2009) Dawn Fedor et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The Role of Polyunsaturated Fatty Acids (PUFA) in the Treatment of Dyslipidemias

(2009) G. Zuliani et al.   CURRENT PHARMACEUTICAL DESIGN

Fenofibrate Simultaneously Induces Hepatic Fatty Acid Oxidation, Synthesis, and Elongation in Mice

(2009) Maaike H. Oosterveer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants

(2009) Sekar Kathiresan et al.   NATURE GENETICS

Protective Role of Autophagy in Palmitate-Induced INS-1 β-Cell Death

(2008) Sung-E Choi et al.   ENDOCRINOLOGY

Endocytosis of Apolipoprotein A-V by Members of the Low Density Lipoprotein Receptor and the Vps10p Domain Receptor Families

(2008) Stefan K. Nilsson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans

(2008) Sekar Kathiresan et al.   NATURE GENETICS