Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice
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Title
Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 122, Issue 5, Pages 1677-1687
Publisher
American Society for Clinical Investigation
Online
2012-04-02
DOI
10.1172/jci61248
References
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Note: Only part of the references are listed.- Sortilin: An unusual suspect in cholesterol metabolism
- (2011) Joseph B. Dubé et al. BIOESSAYS
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- Sorting Out Sortilin
- (2011) Alan R. Tall et al. CIRCULATION RESEARCH
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- (2011) Ali J. Marian Current Atherosclerosis Reports
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- (2011) Ken Inoki et al. JOURNAL OF CLINICAL INVESTIGATION
- Tuberous Sclerosis Complex-1 Deficiency Attenuates Diet-Induced Hepatic Lipid Accumulation
- (2011) Heidi L. Kenerson et al. PLoS One
- With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
- (2010) Pankaj Kapahi et al. Cell Metabolism
- Sort1, Encoded by the Cardiovascular Risk Locus 1p13.3, Is a Regulator of Hepatic Lipoprotein Export
- (2010) Mads Kjolby et al. Cell Metabolism
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- (2010) Shomit Sengupta et al. NATURE
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- Genome-Wide Association Studies Identify New Targets in Cardiovascular Disease
- (2010) A. C. Calkin et al. Science Translational Medicine
- Involvement of TNF-α in abnormal adipocyte and muscle sortilin expression in obese mice and humans
- (2009) V. Kaddai et al. DIABETOLOGIA
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- (2009) R. Takii et al. JOURNAL OF IMMUNOLOGY
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- (2009) Sana Basseri et al. JOURNAL OF LIPID RESEARCH
- Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants
- (2009) Sekar Kathiresan et al. NATURE GENETICS
- Sortilin mediates the lysosomal targeting of cathepsins D and H
- (2008) Maryssa Canuel et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- Loss of the Tuberous Sclerosis Complex Tumor Suppressors Triggers the Unfolded Protein Response to Regulate Insulin Signaling and Apoptosis
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- Presecretory oxidation, aggregation, and autophagic destruction of apoprotein-B: A pathway for late-stage quality control
- (2008) M. Pan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Palmitoylation Controls Recycling in Lysosomal Sorting and Trafficking
- (2008) Peter J. McCormick et al. TRAFFIC
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