Characterization of the Raptor/4E-BP1 Interaction by Chemical Cross-linking Coupled with Mass Spectrometry Analysis

Evaluating protein interactions through cross-linking mass spectrometry

(2012) David L Tabb   NATURE METHODS

Identification of cross-linked peptides from complex samples

(2012) Bing Yang et al.   NATURE METHODS

Smooth statistical torsion angle potential derived from a large conformational database via adaptive kernel density estimation improves the quality of NMR protein structures

(2012) Guillermo A. Bermejo et al.   PROTEIN SCIENCE

Structural Insights into the Allosteric Effects of 4EBP1 on the Eukaryotic Translation Initiation Factor eIF4E

(2011) Nadeem Siddiqui et al.   JOURNAL OF MOLECULAR BIOLOGY

Structural basis for nematode eIF4E binding an m 2,2,7 G-Cap and its implications for translation initiation

(2011) Weizhi Liu et al.   NUCLEIC ACIDS RESEARCH

Chemical Cross-Linking and Mass Spectrometry As a Low-Resolution Protein Structure Determination Technique

(2010) Pragya Singh et al.   ANALYTICAL CHEMISTRY

Genetic Dissection of the Oncogenic mTOR Pathway Reveals Druggable Addiction to Translational Control via 4EBP-eIF4E

(2010) Andrew C. Hsieh et al.   CANCER CELL

4E-BP1 Is a Key Effector of the Oncogenic Activation of the AKT and ERK Signaling Pathways that Integrates Their Function in Tumors

(2010) Qing-Bai She et al.   CANCER CELL

Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry

(2010) Zhuo Angel Chen et al.   EMBO JOURNAL

Probing Native Protein Structures by Chemical Cross-linking, Mass Spectrometry, and Bioinformatics

(2010) Alexander Leitner et al.   MOLECULAR & CELLULAR PROTEOMICS

Structure of the Human mTOR Complex I and Its Implications for Rapamycin Inhibition

(2010) Calvin K. Yip et al.   MOLECULAR CELL

I-TASSER: a unified platform for automated protein structure and function prediction

(2010) Ambrish Roy et al.   Nature Protocols

Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer

(2010) T Sato et al.   ONCOGENE

Molecular targeting of the oncogene eIF4E in acute myeloid leukemia (AML): a proof-of-principle clinical trial with ribavirin

(2009) S. Assouline et al.   BLOOD

mTOR and the control of whole body metabolism

(2009) Pazit Polak et al.   CURRENT OPINION IN CELL BIOLOGY

Structural Insights into Parasite eIF4E Binding Specificity for m7G and m2,2,7G mRNA Caps

(2009) Weizhi Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Specific Activation of mTORC1 by Rheb G-proteinin VitroInvolves Enhanced Recruitment of Its Substrate Protein

(2009) Tatsuhiro Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTOR signaling at a glance

(2009) M. Laplante et al.   JOURNAL OF CELL SCIENCE

Analysis of the regulatory motifs in eukaryotic initiation factor 4E-binding protein 1

(2008) Vivian H. Y. Lee et al.   FEBS Journal

Erratum: Corrigendum: Identification of cross-linked peptides from large sequence databases

(2008) Oliver Rinner et al.   NATURE METHODS

mTOR Is Activated in the Majority of Malignant Melanomas

(2007) Magdalena Karbowniczek et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY