Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer

Cell Cycle Control by the CDC25 Phosphatases

(2012) Bernadette Aressy et al.   Anti-Cancer Agents in Medicinal Chemistry

Specific Activation of mTORC1 by Rheb G-proteinin VitroInvolves Enhanced Recruitment of Its Substrate Protein

(2009) Tatsuhiro Sato et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nutrient control of TORC1, a cell-cycle regulator

(2009) Xuemin Wang et al.   TRENDS IN CELL BIOLOGY

Isolation of Hyperactive Mutants of Mammalian Target of Rapamycin

(2008) Yoichiro Ohne et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

mTOR Is Activated in the Majority of Malignant Melanomas

(2007) Magdalena Karbowniczek et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY