Triggering Receptor Expressed on Myeloid Cells 1 (TREM-1)-mediated Bcl-2 Induction Prolongs Macrophage Survival

The BCL-2–like protein CED-9 ofC. eleganspromotes FZO-1/Mfn1,2– and EAT-3/Opa1–dependent mitochondrial fusion

(2016) Stéphane G. Rolland et al.   JOURNAL OF CELL BIOLOGY

Egr2 Is Required for Bcl-2 Induction during Positive Selection

(2014) J.-P. H. Lauritsen et al.   JOURNAL OF IMMUNOLOGY

Innate Immune Responses to TREM-1 Activation: Overlap, Divergence, and Positive and Negative Cross-Talk with Bacterial Lipopolysaccharide

(2014) K. Dower et al.   JOURNAL OF IMMUNOLOGY

Targeting caspases in cancer therapeutics

(2013) Patrick Hensley et al.   BIOLOGICAL CHEMISTRY

Changes in macrophage phenotype as the immune response evolves

(2013) Julia Lichtnekert et al.   CURRENT OPINION IN PHARMACOLOGY

Tumor associated macrophages and neutrophils in cancer

(2013) Maria Rosaria Galdiero et al.   IMMUNOBIOLOGY

Tumour necrosis factor receptors and apoptosis of alveolar macrophages during early infection with attenuated and virulentMycobacterium bovis

(2013) Michele F. Rodrigues et al.   IMMUNOLOGY

TREM-1 inhibition attenuates inflammation and tumor within the colon

(2013) Jiangang Zhou et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Extrinsic and intrinsic control of macrophage inflammatory responses

(2013) Heather B. Cohen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Pathways mediating resolution of inflammation: when enough is too much

(2013) James N Fullerton et al.   JOURNAL OF PATHOLOGY

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Lung Macrophages Contribute to House Dust Mite Driven Airway Remodeling via HIF-1α

(2013) Adam J. Byrne et al.   PLoS One

Burning Down the House: Cellular Actions during Pyroptosis

(2013) Christopher N. LaRock et al.   PLoS Pathogens

The Proinflammatory Myeloid Cell Receptor TREM-1 Controls Kupffer Cell Activation and Development of Hepatocellular Carcinoma

(2012) Juan Wu et al.   CANCER RESEARCH

Expression of TREM-1 in hepatic stellate cells and prognostic value in hepatitis B-related hepatocellular carcinoma

(2012) Rui Liao et al.   CANCER SCIENCE

Curcumin mediated epigenetic modulation inhibits TREM-1 expression in response to lipopolysaccharide

(2012) Zhihong Yuan et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Tumor associated macrophages and neutrophils in tumor progression

(2012) Maria R. Galdiero et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Transepithelial migration of neutrophils into the lung requires TREM-1

(2012) Julia Klesney-Tait et al.   JOURNAL OF CLINICAL INVESTIGATION

Macrophage plasticity and polarization in tissue repair and remodelling

(2012) Alberto Mantovani et al.   JOURNAL OF PATHOLOGY

Alternatively Activated Macrophages and Airway Disease

(2011) Derek E. Byers et al.   CHEST

Programmed cell death: Apoptosis meets necrosis

(2011) Marcus E. Peter   NATURE

Bcl-2 family interaction with the mitochondrial morphogenesis machinery

(2010) M M Cleland et al.   CELL DEATH AND DIFFERENTIATION

New role of the BCL2 family of proteins in the regulation of mitochondrial dynamics

(2010) Stephane G Rolland et al.   CURRENT OPINION IN CELL BIOLOGY

Expression of TREM-1 is inhibited by PGD2 and PGJ2 in macrophages

(2010) Mansoor Ali Syed et al.   EXPERIMENTAL CELL RESEARCH

Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus

(2010) K. Myouzen et al.   HUMAN MOLECULAR GENETICS

EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin

(2010) Joerg Kumbrink et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

“Where, O Death, Is Thy Sting?” A Brief Review of Apoptosis Biology

(2010) Andrew H. Wyllie   MOLECULAR NEUROBIOLOGY

IL-6 Protects against Hyperoxia-Induced Mitochondrial Damage via Bcl-2–Induced Bak Interactions with Mitofusions

(2009) Aaron B. Waxman et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Anti-Apoptotic Genes in the Survival of Monocytic Cells During Infection

(2009) Aurelia Busca et al.   CURRENT GENOMICS

TREM and TREM-like receptors in inflammation and disease

(2009) Jill W Ford et al.   CURRENT OPINION IN IMMUNOLOGY

Early growth response 2 regulates the survival of thymocytes during positive selection

(2009) Victoria J. Lawson et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MYD88-dependent and -independent activation of TREM-1 via specific TLR ligands

(2009) Heng Zheng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

It's up to you Egr2

(2009) Hamid Bassiri et al.   IMMUNOLOGY AND CELL BIOLOGY

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells

(2009) Vanja Lazarevic et al.   NATURE IMMUNOLOGY

Calcineurin/NFAT Signaling Is Required for Neuregulin-Regulated Schwann Cell Differentiation

(2009) S.-C. Kao et al.   SCIENCE

Involvement of Bcl-2 Family in Apoptosis and Signal Pathways Induced by Cigarette Smoke Extract in the Human Airway Smooth Muscle Cells

(2008) Weihua Hu et al.   DNA AND CELL BIOLOGY

The TREM-1/DAP12 pathway

(2008) Anja S. Tessarz et al.   IMMUNOLOGY LETTERS

Active Gene Repression by the Egr2·NAB Complex during Peripheral Nerve Myelination

(2008) Gennifer M. Mager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Late CD8+ T Cell-Dependent Xenoantibody Production in Innate Tolerant Nude Rats After Hamster Islet Grafting But Not After Hamster Heart Grafting

(2008) Timothy Devos et al.   TRANSPLANTATION

TREM-1 Expression in Tumor-associated Macrophages and Clinical Outcome in Lung Cancer

(2007) Chao-Chi Ho et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Apoptosis: controlled demolition at the cellular level

(2007) Rebecca C. Taylor et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY