Resveratrol selectively induces apoptosis in malignant cells with the JAK2V617F mutation by inhibiting the JAK2 pathway

Molecular insights into regulation of JAK2 in myeloproliferative neoplasms

(2015) O. Silvennoinen et al.   BLOOD

Resveratrol nanoformulations: Challenges and opportunities

(2015) Natalie Summerlin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Resveratrol attenuates lipopolysaccharide-induced acute kidney injury by suppressing inflammation driven by macrophages

(2015) Liang Chen et al.   MOLECULAR NUTRITION & FOOD RESEARCH

SIAH2 antagonizes TYK2-STAT3 signaling in lung carcinoma cells

(2015) Sylvia Müller et al.   Oncotarget

Inhibition of STAT3 Expression and Signaling in Resveratrol-Differentiated Medulloblastoma Cells

(2015) Li-Jun Yu et al.   NEOPLASIA

Janus kinase inhibitors for the treatment of myeloproliferative neoplasms

(2014) Allison Rosenthal et al.   EXPERT OPINION ON PHARMACOTHERAPY

Preclinical characterization of the CDK4/6 inhibitor LY2835219: in-vivo cell cycle-dependent/independent anti-tumor activities alone/in combination with gemcitabine

(2014) Lawrence M. Gelbert et al.   INVESTIGATIONAL NEW DRUGS

3-O-methylthespesilactam, a new small-molecule anticancer pan-JAK inhibitor against A2058 human melanoma cells

(2013) Min-Yi Li et al.   BIOCHEMICAL PHARMACOLOGY

Ataxia-telangiectasia mutated kinase-mediated upregulation of NKG2D ligands on leukemia cells by resveratrol results in enhanced natural killer cell susceptibility

(2013) J. Luis Espinoza et al.   CANCER SCIENCE

JAK Inhibitors: Pharmacology and Clinical Activity in Chronic Myeloprolipherative Neoplasms

(2013) J. Trelinski et al.   CURRENT MEDICINAL CHEMISTRY

Sensitivity and resistance of JAK2 inhibitors to myeloproliferative neoplasms

(2013) Neha Bhagwat et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

ERK1/2 inhibition enhances apoptosis induced by JAK2 silencing in human gastric cancer SGC7901 cells

(2013) Cuijuan Qian et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Review of recent data on the metabolism, biological effects, and toxicity of resveratrol in humans

(2013) Charles-Henry Cottart et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Resveratrol Induces Cell Cycle Arrest and Apoptosis in Malignant NK Cells via JAK2/STAT3 Pathway Inhibition

(2013) Ly Quoc Trung et al.   PLoS One

Resveratrol Inhibits the Growth of Gastric Cancer by Inducing G1 Phase Arrest and Senescence in a Sirt1-Dependent Manner

(2013) Qing Yang et al.   PLoS One

Resveratrol: A Natural Polyphenol with Multiple Chemopreventive Properties (Review)

(2012) Fabrizia Brisdelli et al.   CURRENT DRUG METABOLISM

Heterodimeric JAK–STAT activation as a mechanism of persistence to JAK2 inhibitor therapy

(2012) Priya Koppikar et al.   NATURE

Resveratrol Prevents EBV Transformation and Inhibits the Outgrowth of EBV-Immortalized Human B Cells

(2012) J. Luis Espinoza et al.   PLoS One

Clinical trials of resveratrol

(2011) Ketan R. Patel et al.   Annals of the New York Academy of Sciences

Bim and Mcl-1 exert key roles in regulating JAK2V617Fcell survival

(2011) Joëlle Rubert et al.   BMC CANCER

Resveratrol - pills to replace a healthy diet?

(2011) Veronique S. Chachay et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Phase I Randomized, Double-Blind Pilot Study of Micronized Resveratrol (SRT501) in Patients with Hepatic Metastases--Safety, Pharmacokinetics, and Pharmacodynamics

(2011) L. M. Howells et al.   Cancer Prevention Research

Resveratrol in human cancer chemoprevention - Choosing the ‘right’ dose

(2011) Edwina Scott et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Enhancing the bioavailability of resveratrol by combining it with piperine

(2011) Jeremy J. Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms

(2011) M Nakatake et al.   ONCOGENE

Efficacy of NS-018, a potent and selective JAK2/Src inhibitor, in primary cells and mouse models of myeloproliferative neoplasms

(2011) Y Nakaya et al.   Blood Cancer Journal

Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia

(2010) Monika Podhorecka et al.   ANNALS OF HEMATOLOGY

Preclinical characterization of the selective JAK1/2 inhibitor INCB018424: therapeutic implications for the treatment of myeloproliferative neoplasms

(2010) A. Quintas-Cardama et al.   BLOOD

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Repeat Dose Study of the Cancer Chemopreventive Agent Resveratrol in Healthy Volunteers: Safety, Pharmacokinetics, and Effect on the Insulin-like Growth Factor Axis

(2010) V. A. Brown et al.   CANCER RESEARCH

Modulation of Akt and ERK1/2 Pathways by Resveratrol in Chronic Myelogenous Leukemia (CML) Cells Results in the Downregulation of Hsp70

(2010) Soumyajit Banerjee Mustafi et al.   PLoS One

Resveratrol bioavailability and toxicity in humans

(2009) Charles-Henry Cottart et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Bioproduction of resveratrol and stilbene derivatives by plant cells and microorganisms

(2009) David Donnez et al.   TRENDS IN BIOTECHNOLOGY

Resveratrol addiction: To die or not to die

(2008) Mehdi Shakibaei et al.   MOLECULAR NUTRITION & FOOD RESEARCH

JAKs in pathology: Role of Janus kinases in hematopoietic malignancies and immunodeficiencies

(2008) William Vainchenker et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY