JAK2V617F negatively regulates p53 stabilization by enhancing MDM2 via La expression in myeloproliferative neoplasms

Analysis of the p53 and MDM-2 gene in acute myeloid leukemia

(2010) Barbara Seliger et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Pathogenesis of the erythroid failure in Diamond Blackfan anaemia

(2009) Colin A. Sieff et al.   BRITISH JOURNAL OF HAEMATOLOGY

JAK2 phosphorylates histone H3Y41 and excludes HP1α from chromatin

(2009) Mark A. Dawson et al.   NATURE

Small-Molecule Inhibitors of the MDM2-p53 Protein-Protein Interaction to Reactivate p53 Function: A Novel Approach for Cancer Therapy

(2008) Sanjeev Shangary et al.   Annual Review of Pharmacology and Toxicology

JAK2 stimulates homologous recombination and genetic instability: potential implication in the heterogeneity of myeloproliferative disorders

(2008) I. Plo et al.   BLOOD

Cytogenetic studies at diagnosis in polycythemia vera: clinical and JAK2V617F allele burden correlates

(2008) Naseema Gangat et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Genetic profiling of myeloproliferative disorders by single-nucleotide polymorphism oligonucleotide microarray

(2008) Norihiko Kawamata et al.   EXPERIMENTAL HEMATOLOGY

Oligonucleotide array CGH studies in myeloproliferative neoplasms: Comparison with JAK2V617F mutational status and conventional chromosome analysis

(2008) Ayalew Tefferi et al.   LEUKEMIA RESEARCH

p53 mRNA controls p53 activity by managing Mdm2 functions

(2008) Marco M. Candeias et al.   NATURE CELL BIOLOGY

Inhibition of the Bcl-xLDeamidation Pathway in Myeloproliferative Disorders

(2008) Rui Zhao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ratio of mutant JAK2-V617F to wild-type Jak2 determines the MPD phenotypes in transgenic mice

(2007) R. Tiedt et al.   BLOOD