Post-Stroke Inhibition of Induced NADPH Oxidase Type 4 Prevents Oxidative Stress and Neurodegeneration

Impaired  IIb 3 Integrin Activation and Shear-Dependent Thrombus Formation in Mice Lacking Phospholipase D1

(2010) M. Elvers et al.   Science Signaling

Publication Bias in Reports of Animal Stroke Studies Leads to Major Overstatement of Efficacy

(2010) Emily S. Sena et al.   PLOS BIOLOGY

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Decision Analysis Supports the Paradigm That Indiscriminate Supplementation of Vitamin E Does More Harm than Good

(2009) Yedidya Dotan et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Deficiency of von Willebrand factor protects mice from ischemic stroke

(2009) C. Kleinschnitz et al.   BLOOD

Reduction of cerebral infarct volume by apocynin requires pretreatment and is absent in Nox2-deficient mice

(2009) KA Jackman et al.   BRITISH JOURNAL OF PHARMACOLOGY

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish

(2009) Philipp Niethammer et al.   NATURE

Enhanced cortical reperfusion protects coagulation factor XII-deficient mice from ischemic stroke as revealed by high-field MRI

(2009) M. Pham et al.   NEUROIMAGE

Subcellular localization of Nox4 and regulation in diabetes

(2009) K. Block et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

STIM2 Regulates Capacitive Ca2+ Entry in Neurons and Plays a Key Role in Hypoxic Neuronal Cell Death

(2009) A. Berna-Erro et al.   Science Signaling

Update of the Stroke Therapy Academic Industry Roundtable Preclinical Recommendations

(2009) Marc Fisher et al.   STROKE

Why Have Antioxidants Failed in Clinical Trials?

(2008) Steven R. Steinhubl   AMERICAN JOURNAL OF CARDIOLOGY

Nox4 and Nox2 NADPH Oxidases Mediate Distinct Cellular Redox Signaling Responses to Agonist Stimulation

(2008) Narayana Anilkumar et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Apocynin-induced vasodilation involves Rho kinase inhibition but not NADPH oxidase inhibition

(2008) T. Schluter et al.   CARDIOVASCULAR RESEARCH

Platelet-derived growth factor BB stimulates vasculogenesis of embryonic stem cell-derived endothelial cells by calcium-mediated generation of reactive oxygen species

(2008) S. Lange et al.   CARDIOVASCULAR RESEARCH

ADMA Impairs Nitric Oxide–Mediated Arteriolar Function Due to Increased Superoxide Production by Angiotensin II–NAD(P)H Oxidase Pathway

(2008) Zoltan Veresh et al.   HYPERTENSION

Early increase of Nox4 NADPH oxidase and superoxide generation following endothelin-1-induced stroke in conscious rats

(2008) Sarah K. McCann et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Blood-brain barrier tight junction permeability and ischemic stroke

(2008) Karin E. Sandoval et al.   NEUROBIOLOGY OF DISEASE

The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice

(2008) Sven G. Meuth et al.   NEUROBIOLOGY OF DISEASE

Blocking of Platelets or Intrinsic Coagulation Pathway–Driven Thrombosis Does Not Prevent Cerebral Infarctions Induced by Photothrombosis

(2008) Christoph Kleinschnitz et al.   STROKE

Empirical Evidence of Bias in the Design of Experimental Stroke Studies

(2008) Nicolas A. Crossley et al.   STROKE

Blockade of Bradykinin Receptor B1 but Not Bradykinin Receptor B2 Provides Protection From Cerebral Infarction and Brain Edema

(2008) Madeleine Austinat et al.   STROKE

Good Laboratory Practice

(2008) Malcolm R. Macleod et al.   STROKE

Apocynin, NADPH Oxidase, and Vascular Cells

(2007) Rhian M. Touyz   HYPERTENSION

Apocynin Is Not an Inhibitor of Vascular NADPH Oxidases but an Antioxidant

(2007) Sabine Heumüller et al.   HYPERTENSION