Inhibition of Peripheral TNF-α and Downregulation of Microglial Activation by Alpha-Lipoic Acid and Etanercept Protect Rat Brain Against Ischemic Stroke

Microglial Activation as a Compelling Target for Treating Acute Traumatic Brain Injury

(2015) Chung-Ching Chio et al.   CURRENT MEDICINAL CHEMISTRY

Peripheral Frequency of CD4+ CD28− Cells in Acute Ischemic Stroke

(2015) Antonino Tuttolomondo et al.   MEDICINE

Alpha-lipoic acid treatment is neurorestorative and promotes functional recovery after stroke in rats

(2015) Kang-Ho Choi et al.   Molecular Brain

Tumor necrosis factor-α inhibition attenuates middle cerebral artery remodeling but increases cerebral ischemic damage in hypertensive rats

(2014) Paulo W. Pires et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia

(2014) Yun Yuan et al.   BMC NEUROSCIENCE

Immediate Neurological Recovery Following Perispinal Etanercept Years After Brain Injury

(2014) Edward Tobinick et al.   CLINICAL DRUG INVESTIGATION

Ligustilide ameliorates neuroinflammation and brain injury in focal cerebral ischemia/reperfusion rats: involvement of inhibition of TLR4/peroxiredoxin 6 signaling

(2014) Xi Kuang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Microglia is a Key Player in the Reduction of Stroke Damage Promoted by the New Antithrombotic Agent Ticagrelor

(2014) Paolo Gelosa et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Middle cerebral artery occlusion methods in rat versus mouse models of transient focal cerebral ischemic stroke

(2014) Seunghoon Lee et al.   Neural Regeneration Research

Alpha-lipoic acid upregulates SIRT1-dependent PGC-1α expression and protects mouse brain against focal ischemia

(2014) B. Fu et al.   NEUROSCIENCE

Etanercept attenuates traumatic brain injury in rats by reducing early microglial expression of tumor necrosis factor-α

(2013) Chung-Ching Chio et al.   BMC NEUROSCIENCE

Propofol Protects Against Focal Cerebral Ischemia via Inhibition of Microglia-Mediated Proinflammatory Cytokines in a Rat Model of Experimental Stroke

(2013) Rong Zhou et al.   PLoS One

Arterial stiffness and ischemic stroke in subjects with and without metabolic syndrome

(2012) Antonino Tuttolomondo et al.   ATHEROSCLEROSIS

Selective TNF Inhibition for Chronic Stroke and Traumatic Brain Injury

(2012) Edward Tobinick et al.   CNS DRUGS

Inflammation in Ischemic Stroke Subtypes

(2012) Antonino Tuttolomondo et al.   CURRENT PHARMACEUTICAL DESIGN

Single nucleotide polymorphisms (SNPs) of pro-inflammatory/anti-inflammatory and thrombotic/fibrinolytic genes in patients with acute ischemic stroke in relation to TOAST subtype

(2012) Antonino Tuttolomondo et al.   CYTOKINE

Inflammatory Cytokines in Experimental and Human Stroke

(2012) Kate Lykke Lambertsen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Novel therapeutic strategies targeting innate immune responses and early inflammation after stroke

(2012) Takashi Shichita et al.   JOURNAL OF NEUROCHEMISTRY

CD40 Ligand and MCP-1 as Predictors of Cardiovascular Events in Diabetic Patients with Stroke

(2011) Giovanni Davì et al.   Journal of Atherosclerosis and Thrombosis

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Immune-inflammatory markers and arterial stiffness indexes in subjects with acute ischemic stroke

(2010) Antonino Tuttolomondo et al.   ATHEROSCLEROSIS

Lipoic acid protects against reperfusion injury in the early stages of cerebral ischemia

(2010) Barry J. Connell et al.   BRAIN RESEARCH

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Therapeutic evaluation of etanercept in a model of traumatic brain injury

(2010) Chung-Ching Chio et al.   JOURNAL OF NEUROCHEMISTRY

Alpha-Lipoic Acid Modulates GFAP, Vimentin, Nestin, Cyclin D1 and MAP-Kinase Espression in Astroglial Cell Cultures

(2010) V. Bramanti et al.   NEUROCHEMICAL RESEARCH

Fetuin-A and CD40 L plasma levels in acute ischemic stroke: Differences in relation to TOAST subtype and correlation with clinical and laboratory variables

(2009) A. Tuttolomondo et al.   ATHEROSCLEROSIS

Inflammation and brain injury: Acute cerebral ischaemia, peripheral and central inflammation

(2009) A. Denes et al.   BRAIN BEHAVIOR AND IMMUNITY

The complexity of neurobiological processes in acute ischemic stroke

(2009) R. Brouns et al.   CLINICAL NEUROLOGY AND NEUROSURGERY

Post-injury baicalein improves histological and functional outcomes and reduces inflammatory cytokines after experimental traumatic brain injury

(2008) S-F Chen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Immuno-inflammatory predictors of stroke at follow-up in patients with chronic non-valvular atrial fibrillation (NVAF)

(2008) Antonio Pinto et al.   CLINICAL SCIENCE

TNF signaling inhibition in the CNS: implications for normal brain function and neurodegenerative disease

(2008) Melissa K McCoy et al.   Journal of Neuroinflammation

Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases

(2008) Y. Jiang et al.   NEUROBIOLOGY OF DISEASE

An inclined plane system with microcontroller to determine limb motor function of laboratory animals

(2007) Ming-Wen Chang et al.   JOURNAL OF NEUROSCIENCE METHODS