microRNAs with different functions and roles in disease development and as potential biomarkers of diabetes: progress and challenges

Cancer Exosomes Perform Cell-Independent MicroRNA Biogenesis and Promote Tumorigenesis

(2014) Sonia A. Melo et al.   CANCER CELL

Following the Fate of the Failing  -Cell: New Insights From First-Phase Insulin Responses

(2014) A. J. K. Williams et al.   DIABETES

Profiling of Circulating MicroRNAs Reveals Common MicroRNAs Linked to Type 2 Diabetes That Change With Insulin Sensitization

(2014) Francisco J. Ortega et al.   DIABETES CARE

Malicious exosomes

(2014) Eleni Anastasiadou et al.   SCIENCE

Exosome in Tumour Microenvironment: Overview of the Crosstalk between Normal and Cancer Cells

(2014) Catarina Roma-Rodrigues et al.   Biomed Research International

Argonaute2 Mediates Compensatory Expansion of the Pancreatic β Cell

(2013) Sudhir G. Tattikota et al.   Cell Metabolism

Circulating miR-375 as a Biomarker of β-Cell Death and Diabetes in Mice

(2013) Suheda Erener et al.   ENDOCRINOLOGY

Circulating microRNAs as novel biomarkers for diabetes mellitus

(2013) Claudiane Guay et al.   Nature Reviews Endocrinology

Circulating MicroRNAs

(2012) Esther E. Creemers et al.   CIRCULATION RESEARCH

MicroRNAs in Vascular and Metabolic Disease

(2012) Anna Zampetaki et al.   CIRCULATION RESEARCH

Use of Circulating MicroRNAs to Diagnose Acute Myocardial Infarction

(2012) Y. Devaux et al.   CLINICAL CHEMISTRY

Great potential of miRNAs as predictive and prognostic markers for cancer

(2012) William CS Cho   EXPERT REVIEW OF MOLECULAR DIAGNOSTICS

MicroRNAs miR-21a and miR-93 are down regulated in peripheral blood mononuclear cells (PBMCs) from patients with type 1 diabetes

(2012) Francisca Salas-Pérez et al.   IMMUNOBIOLOGY

Circulating miRNA Profiles in Patients with Metabolic Syndrome

(2012) Dwi Setyowati Karolina et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

MicroRNA profiling: approaches and considerations

(2012) Colin C. Pritchard et al.   NATURE REVIEWS GENETICS

Circulating Micro-RNAs as Potential Blood-Based Markers for Early Stage Breast Cancer Detection

(2012) Michael G. Schrauder et al.   PLoS One

MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function

(2012) B. H. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response

(2012) M. Fabbri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as Biomarkers, Therapeutic Targets, and Signaling Molecules

(2012) Seena K. Ajit   SENSORS

Secreted microRNAs: a new form of intercellular communication

(2012) Xi Chen et al.   TRENDS IN CELL BIOLOGY

Identification of circulating miRNA biomarkers based on global quantitative real-time PCR profiling

(2012) Kang Kang et al.   Journal of Animal Science and Biotechnology

Microvesicles/exosomes as potential novel biomarkers of metabolic diseases

(2012) Gunter Müller   Diabetes Metabolic Syndrome and Obesity-Targets and Therapy

New methods for next generation sequencing based microRNA expression profiling

(2011) Henk PJ Buermans et al.   BMC GENOMICS

Gap Junction-Mediated Import of MicroRNA from Bone Marrow Stromal Cells Can Elicit Cell Cycle Quiescence in Breast Cancer Cells

(2011) P. K. Lim et al.   CANCER RESEARCH

Profiling of circulating microRNAs: from single biomarkers to re-wired networks

(2011) A. Zampetaki et al.   CARDIOVASCULAR RESEARCH

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

MicroRNAs in  -Cell Biology, Insulin Resistance, Diabetes and Its Complications

(2011) S. L. Fernandez-Valverde et al.   DIABETES

Increased expression of microRNA miR-326 in type 1 diabetic patients with ongoing islet autoimmunity

(2011) Guido Sebastiani et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis

(2011) Maarten Hulsmans et al.   FASEB JOURNAL

MicroRNA-146a regulates the maturation process and pro-inflammatory cytokine secretion by targeting CD40L in oxLDL-stimulated dendritic cells

(2011) Ting Chen et al.   FEBS LETTERS

Differential miRNA Expression in Omental Adipose Tissue and in the Circulation of Obese Patients Identifies Novel Metabolic Biomarkers

(2011) H. M. Heneghan et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Diagnostic and prognostic impact of six circulating microRNAs in acute coronary syndrome

(2011) Christian Widera et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

(2011) Mei Yang et al.   Molecular Cancer

Extracellular microRNA: A new source of biomarkers

(2011) Alton Etheridge et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

MicroRNAs 103 and 107 regulate insulin sensitivity

(2011) Mirko Trajkovski et al.   NATURE

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Bring on the biomarkers

(2011) George Poste   NATURE

MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

(2011) Kasey C. Vickers et al.   NATURE CELL BIOLOGY

Mir193b–365 is essential for brown fat differentiation

(2011) Lei Sun et al.   NATURE CELL BIOLOGY

Toward the blood-borne miRNome of human diseases

(2011) Andreas Keller et al.   NATURE METHODS

Global Regulation on microRNA in Hepatitis B Virus-Associated Hepatocellular Carcinoma

(2011) Angela M. Liu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

MicroRNA-21 Exhibits Antiangiogenic Function by Targeting RhoB Expression in Endothelial Cells

(2011) Céline Sabatel et al.   PLoS One

Impact of Cellular miRNAs on Circulating miRNA Biomarker Signatures

(2011) Radha Duttagupta et al.   PLoS One

RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries

(2011) M. Hafner et al.   RNA

MicroRNAs: miRRORS of health and disease

(2011) Monty Montano   Translational Research

MicroRNAs in idiopathic pulmonary fibrosis

(2011) Kusum V. Pandit et al.   Translational Research

MicroRNAs in cardiac disease

(2011) Gerald W. Dorn   Translational Research

Integrating microRNAs into a system biology approach to acute lung injury

(2011) Tong Zhou et al.   Translational Research

Diabetes mellitus, a microRNA-related disease?

(2011) Claudiane Guay et al.   Translational Research

Significance of serum microRNAs in pre-diabetes and newly diagnosed type 2 diabetes: a clinical study

(2010) Lei Kong et al.   ACTA DIABETOLOGICA

microRNA-222 Controls Neovascularization by Regulating Signal Transducer and Activator of Transcription 5A Expression

(2010) Patrizia Dentelli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Adipocyte-derived microvesicles contain RNA that is transported into macrophages and might be secreted into blood circulation

(2010) Rumiko Ogawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sequencing bias: comparison of different protocols of MicroRNA library construction

(2010) Geng Tian et al.   BMC BIOTECHNOLOGY

Downregulation of microRNA-29 by antisense inhibitors and a PPAR-γ agonist protects against myocardial ischaemia–reperfusion injury

(2010) Yumei Ye et al.   CARDIOVASCULAR RESEARCH

Ischaemic preconditioning-regulated miR-21 protects heart against ischaemia/reperfusion injury via anti-apoptosis through its target PDCD4

(2010) Y. Cheng et al.   CARDIOVASCULAR RESEARCH

Function of miR-146a in Controlling Treg Cell-Mediated Regulation of Th1 Responses

(2010) Li-Fan Lu et al.   CELL

Circulating MicroRNAs in Patients With Coronary Artery Disease

(2010) Stephan Fichtlscherer et al.   CIRCULATION RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

A translational study of circulating cell-free microRNA-1 in acute myocardial infarction

(2010) Yunhui Cheng et al.   CLINICAL SCIENCE

Serum microRNA characterization identifiesmiR-885-5pas a potential marker for detecting liver pathologies

(2010) Junhao Gui et al.   CLINICAL SCIENCE

Circulating microRNAs: Association with disease and potential use as biomarkers

(2010) Glen Reid et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Secretory Mechanisms and Intercellular Transfer of MicroRNAs in Living Cells

(2010) Nobuyoshi Kosaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro

(2010) Manuela Quintavalle et al.   JOURNAL OF CELL BIOLOGY

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism

(2010) Dimitrios Iliopoulos et al.   JOURNAL OF LIPID RESEARCH

MicroRNA 92a-2*: A Biomarker Predictive for Chemoresistance and Prognostic for Survival in Patients with Small Cell Lung Cancer

(2010) Aarati R. Ranade et al.   Journal of Thoracic Oncology

Secreted Monocytic miR-150 Enhances Targeted Endothelial Cell Migration

(2010) Yujing Zhang et al.   MOLECULAR CELL

MicroRNAs under the spotlight in inflammatory arthritis

(2010) Jenny Buckland   Nature Reviews Rheumatology

MicroRNAs as biomarkers in rheumatic diseases

(2010) Ilias Alevizos et al.   Nature Reviews Rheumatology

miRTarBase: a database curates experimentally validated microRNA–target interactions

(2010) Sheng-Da Hsu et al.   NUCLEIC ACIDS RESEARCH

Up-Regulated Pancreatic Tissue MicroRNA-375 Associates With Human Type 2 Diabetes Through β-Cell Deficit and Islet Amyloid Deposition

(2010) Hailu Zhao et al.   PANCREAS

MiRNA Expression Profile of Human Subcutaneous Adipose and during Adipocyte Differentiation

(2010) Francisco J. Ortega et al.   PLoS One

Microvesicles Derived from Adult Human Bone Marrow and Tissue Specific Mesenchymal Stem Cells Shuttle Selected Pattern of miRNAs

(2010) Federica Collino et al.   PLoS One

Selective Release of MicroRNA Species from Normal and Malignant Mammary Epithelial Cells

(2010) Lucy Pigati et al.   PLoS One

miR-33 links SREBP-2 induction to repression of sterol transporters

(2010) T. J. Marquart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic isomiR regulation in Drosophila development

(2010) S. L. Fernandez-Valverde et al.   RNA

Complexity of the microRNA repertoire revealed by next-generation sequencing

(2010) L. W. Lee et al.   RNA

MiR-33 Contributes to the Regulation of Cholesterol Homeostasis

(2010) K. J. Rayner et al.   SCIENCE

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

(2010) Iain J Gallagher et al.   Genome Medicine

Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk

(2010) Christin E. Burd et al.   PLoS Genetics

Trends in microRNA detection

(2009) Kyle A. Cissell et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Circulating microRNA-1 as a potential novel biomarker for acute myocardial infarction

(2009) Jing Ai et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

An emerging player in the adaptive immune response: microRNA-146a is a modulator of IL-2 expression and activation-induced cell death in T lymphocytes

(2009) G. Curtale et al.   BLOOD

Reproducibility of quantitative RT-PCR array in miRNA expression profiling and comparison with microarray analysis

(2009) Yongxin Chen et al.   BMC GENOMICS

MicroRNA-1 downregulation by propranolol in a rat model of myocardial infarction: a new mechanism for ischaemic cardioprotection

(2009) Yanjie Lu et al.   CARDIOVASCULAR RESEARCH

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

Plasma miR-208 as a Biomarker of Myocardial Injury

(2009) X. Ji et al.   CLINICAL CHEMISTRY

The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element-Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway

(2009) A. Granjon et al.   DIABETES

MicroRNAs Induced During Adipogenesis that Accelerate Fat Cell Development Are Downregulated in Obesity

(2009) H. Xie et al.   DIABETES

Development of a Type 2 Diabetes Risk Model From a Panel of Serum Biomarkers From the Inter99 Cohort

(2009) J. A. Kolberg et al.   DIABETES CARE

MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types

(2009) Richard Hummel et al.   EUROPEAN JOURNAL OF CANCER

Cell contact-dependent acquisition of cellular and viral nonautonomously encoded small RNAs

(2009) O. Rechavi et al.   GENES & DEVELOPMENT

MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury

(2009) M. Xin et al.   GENES & DEVELOPMENT

MicroRNA expression changes in lymphoblastoid cell lines in response to lithium treatment

(2009) Haiming Chen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Photodynamic therapy induces microRNA-210 and -296 expression in HeLa cells

(2009) Toshihiro Kushibiki   Journal of Biophotonics

Escape from hsa-miR-519c enables drug-resistant cells to maintain high expression of ABCG2

(2009) K. K.W. To et al.   MOLECULAR CANCER THERAPEUTICS

Upregulation of miRNA hsa-miR-342-3p in experimental and idiopathic prion disease

(2009) Judith Montag et al.   Molecular Neurodegeneration

Limitations and possibilities of small RNA digital gene expression profiling

(2009) Sam E V Linsen et al.   NATURE METHODS

Epigenetic and microRNA-mediated regulation in diabetes

(2009) P. Muhonen et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Meta-analysis of small RNA-sequencing errors reveals ubiquitous post-transcriptional RNA modifications

(2009) H. Alexander Ebhardt et al.   NUCLEIC ACIDS RESEARCH

Role of microRNAs in obesity and the metabolic syndrome

(2009) H. M. Heneghan et al.   Obesity Reviews

Epigenetic and microRNA-dependent control of cytochrome P450 expression: a gap between DNA and protein

(2009) Alvin Gomez et al.   PHARMACOGENOMICS

MicroRNA Expression in Human Omental and Subcutaneous Adipose Tissue

(2009) Nora Klöting et al.   PLoS One

Transfer of MicroRNAs by Embryonic Stem Cell Microvesicles

(2009) Alex Yuan et al.   PLoS One

Intra-Platform Repeatability and Inter-Platform Comparability of MicroRNA Microarray Technology

(2009) Fumiaki Sato et al.   PLoS One

Evidence for X-Chromosomal Schizophrenia Associated with microRNA Alterations

(2009) Jinong Feng et al.   PLoS One

MicroRNA Fingerprints Identify miR-150 as a Plasma Prognostic Marker in Patients with Sepsis

(2009) Catalin Vasilescu et al.   PLoS One

miR-375 maintains normal pancreatic  - and  -cell mass

(2009) M. N. Poy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Delivery of MicroRNA-126 by Apoptotic Bodies Induces CXCL12-Dependent Vascular Protection

(2009) A. Zernecke et al.   Science Signaling

Technical variables in high-throughput miRNA expression profiling: Much work remains to be done

(2008) P NELSON et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Regulation of the expression of components of the exocytotic machinery of insulin-secreting cells by microRNAs

(2008) Pascal Lovis et al.   BIOLOGICAL CHEMISTRY

Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes

(2008) Garrett Sorensen et al.   BMC GENOMICS

Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma

(2008) Charles H. Lawrie et al.   BRITISH JOURNAL OF HAEMATOLOGY

Validation of Analytic Methods for Biomarkers Used in Drug Development

(2008) C. H. Chau et al.   CLINICAL CANCER RESEARCH

miR-126 Regulates Angiogenic Signaling and Vascular Integrity

(2008) Jason E. Fish et al.   DEVELOPMENTAL CELL

miR-375 Targets 3'-Phosphoinositide-Dependent Protein Kinase-1 and Regulates Glucose-Induced Biological Responses in Pancreatic  -Cells

(2008) A. El Ouaamari et al.   DIABETES

Expression of islet-specific microRNAs during human pancreatic development

(2008) Mugdha V. Joglekar et al.   GENE EXPRESSION PATTERNS

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

(2008) Brandi N. Davis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

(2008) Johan Skog et al.   NATURE CELL BIOLOGY

A miRNA Signature of Prion Induced Neurodegeneration

(2008) Reuben Saba et al.   PLoS One

miR-17-92 cluster accelerates adipocyte differentiation by negatively regulating tumor-suppressor Rb2/p130

(2008) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Circulating microRNAs as stable blood-based markers for cancer detection

(2008) P. S. Mitchell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantitative differential expression analysis reveals miR-7 as major islet microRNA

(2007) Valia Bravo-Egana et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS