tRNA Modification Enzymes GidA and MnmE: Potential Role in Virulence of Bacterial Pathogens

Posttranscriptional Regulation of 2,4-Diacetylphloroglucinol Production by GidA and TrmE in Pseudomonas fluorescens 2P24

(2014) Wei Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

A System of RNA Modifications and Biased Codon Use Controls Cellular Stress Response at the Level of Translation

(2014) Peter C. Dedon et al.   CHEMICAL RESEARCH IN TOXICOLOGY

A Novel Gene Involved in the Survival of Streptococcus mutans under Stress Conditions

(2013) Dan Li et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

GidA Expression in Salmonella is Modulated Under Certain Environmental Conditions

(2013) Jaclyn M. Rehl et al.   CURRENT MICROBIOLOGY

The Francisella tularensis migR,trmE, andcphAGenes Contribute to F. tularensis Pathogenicity Island Gene Regulation and Intracellular Growth by Modulation of the Stress Alarmone ppGpp

(2013) Matthew Faron et al.   INFECTION AND IMMUNITY

Virulence characteristics of Salmonella following deletion of genes encoding the tRNA modification enzymes GidA and MnmE

(2013) Daniel C. Shippy et al.   MICROBIAL PATHOGENESIS

Lack of tRNA Modification Isopentenyl-A37 Alters mRNA Decoding and Causes Metabolic Deficiencies in Fission Yeast

(2013) T. N. Lamichhane et al.   MOLECULAR AND CELLULAR BIOLOGY

The tRNA-modifying function of MnmE is controlled by post-hydrolysis steps of its GTPase cycle

(2013) Silvia Prado et al.   NUCLEIC ACIDS RESEARCH

Mutations of the Mitochondrial-tRNA Modifier MTO1 Cause Hypertrophic Cardiomyopathy and Lactic Acidosis

(2012) Daniele Ghezzi et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biosynthesis and Function of Posttranscriptional Modifications of Transfer RNAs

(2012) Basma El Yacoubi et al.   Annual Review of Genetics

Enzymology of tRNA modification in the bacterial MnmEG pathway

(2012) M.-Eugenia Armengod et al.   BIOCHIMIE

Immunological characterization of a gidA mutant strain of Salmonella for potential use in a live-attenuated vaccine

(2012) Daniel C Shippy et al.   BMC MICROBIOLOGY

DNA adenine methyltransferase (Dam) controls the expression of the cytotoxic enterotoxin (act) gene of Aeromonas hydrophila via tRNA modifying enzyme-glucose-inhibited division protein (GidA)

(2012) Tatiana E. Erova et al.   GENE

Translational infidelity-induced protein stress results from a deficiency in Trm9-catalyzed tRNA modifications

(2012) Ashish Patil et al.   RNA Biology

Reprogramming of tRNA modifications controls the oxidative stress response by codon-biased translation of proteins

(2012) Clement T.Y. Chan et al.   Nature Communications

Structure-Function Relationships of the G Domain, a Canonical Switch Motif

(2011) Alfred Wittinghofer et al.   Annual Review of Biochemistry

Deletion of glucose-inhibited division (gidA) gene alters the morphological and replication characteristics of Salmonella enterica Serovar typhimurium

(2011) Daniel C. Shippy et al.   ARCHIVES OF MICROBIOLOGY

mRNA context dependent regulation of cytotoxic necrotizing factor 1 translation by GidA, a tRNA modification enzyme in Escherichia coli

(2011) Hao Yu et al.   GENE

Biological and virulence characteristics of Salmonella enterica serovar Typhimurium following deletion of glucose-inhibited division (gidA) gene

(2011) Daniel C. Shippy et al.   MICROBIAL PATHOGENESIS

Assay of both activities of the bifunctional tRNA-modifying enzyme MnmC reveals a kinetic basis for selective full modification of cmnm5s2U to mnm5s2U

(2011) David Pearson et al.   NUCLEIC ACIDS RESEARCH

Elongator Complex Influences Telomeric Gene Silencing and DNA Damage Response by Its Role in Wobble Uridine tRNA Modification

(2011) Changchun Chen et al.   PLoS Genetics

tRNA biology charges to the front

(2010) E. M. Phizicky et al.   GENES & DEVELOPMENT

Identification of Streptococcus suis serotype 2 genes preferentially expressed in the natural host

(2010) Wei Li et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

Acute Infantile Liver Failure Due to Mutations in the TRMU Gene

(2009) Avraham Zeharia et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Importance of trmE for Growth of the Psychrophile Pseudomonas syringae at Low Temperatures

(2009) A. K. Singh et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Structure-Function Analysis of Escherichia coli MnmG (GidA), a Highly Conserved tRNA-Modifying Enzyme

(2009) R. Shi et al.   JOURNAL OF BACTERIOLOGY

GidA Posttranscriptionally Regulates rhl Quorum Sensing in Pseudomonas aeruginosa

(2009) R. Gupta et al.   JOURNAL OF BACTERIOLOGY

Evolutionarily conserved proteins MnmE and GidA catalyze the formation of two methyluridine derivatives at tRNA wobble positions

(2009) Ismaïl Moukadiri et al.   NUCLEIC ACIDS RESEARCH

Conserved Cysteine Residues of GidA Are Essential for Biogenesis of 5-Carboxymethylaminomethyluridine at tRNA Anticodon

(2009) Takuo Osawa et al.   STRUCTURE

Kissing G Domains of MnmE Monitored by X-Ray Crystallography and Pulse Electron Paramagnetic Resonance Spectroscopy

(2009) Simon Meyer et al.   PLOS BIOLOGY

Defects in tRNA Modification Associated with Neurological and Developmental Dysfunctions in Caenorhabditis elegans Elongator Mutants

(2009) Changchun Chen et al.   PLoS Genetics

tRNA's modifications bring order to gene expression

(2008) Estella M Gustilo et al.   CURRENT OPINION IN MICROBIOLOGY

Bringing order to translation: the contributions of transfer RNA anticodon-domain modifications

(2008) Paul F Agris   EMBO REPORTS

tRNA Modification by GidA/MnmE Is Necessary for Streptococcus pyogenes Virulence: a New Strategy To Make Live Attenuated Strains

(2008) K. H. Cho et al.   INFECTION AND IMMUNITY

Crystal Structures of the Conserved tRNA-Modifying Enzyme GidA: Implications for Its Interaction with MnmE and Substrate

(2008) S. Meyer et al.   JOURNAL OF MOLECULAR BIOLOGY

Characterization of Human GTPBP3, a GTP-Binding Protein Involved in Mitochondrial tRNA Modification

(2008) M. Villarroya et al.   MOLECULAR AND CELLULAR BIOLOGY

2,4-Diacetylphloroglucinol Alters Plant Root Development

(2008) Jessica N. Brazelton et al.   MOLECULAR PLANT-MICROBE INTERACTIONS

Sequence-structure-function analysis of the bifunctional enzyme MnmC that catalyses the last two steps in the biosynthesis of hypermodified nucleoside mnm5s2U in tRNA

(2008) Martine Roovers et al.   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS

Modulation of stress and virulence in Listeria monocytogenes

(2008) Soraya Chaturongakul et al.   TRENDS IN MICROBIOLOGY