MLK3-MKK3/6-P38MAPK cascades following N-methyl-D-aspartate receptor activation contributes to amyloid-β peptide-induced apoptosis in SH-SY5Y cells

Grouping and Trajectories of the Neuropsychiatric Symptoms in Patients with Alzheimer's Disease, Part I: Symptom Clusters

(2017) Josep Garre-Olmo et al.   JOURNAL OF ALZHEIMERS DISEASE

Involvement of the GluN2A and GluN2B Subunits in Synaptic and Extrasynaptic N -methyl-d-aspartate Receptor Function and Neuronal Excitotoxicity

(2013) Xianju Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endoplasmic reticulum stress occurs downstream of GluN2B subunit ofN-methyl-D-aspartate receptor in mature hippocampal cultures treated with amyloid-β oligomers

(2012) Rui O. Costa et al.   AGING CELL

Akebia Saponin D attenuates amyloid β-induced cognitive deficits and inflammatory response in rats: Involvement of Akt/NF-κB pathway

(2012) Xing Yu et al.   BEHAVIOURAL BRAIN RESEARCH

Fyn Kinases Play a Critical Role in Neuronal Apoptosis Induced by Oxygen and Glucose Deprivation or Amyloid-β Peptide Treatment

(2012) Cai-Ping Du et al.   CNS Neuroscience & Therapeutics

Memantine prevents cognitive impairment and reduces Bcl-2 and caspase 8 immunoreactivity in rats injected with amyloid β1–40

(2012) José Javier Miguel-Hidalgo et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Protective effects of MK-801 on methylmercury-induced neuronal injury in rat cerebral cortex: Involvement of oxidative stress and glutamate metabolism dysfunction

(2012) Bin Xu et al.   TOXICOLOGY

An anti-Aβ (amyloid β) single-chain variable fragment prevents amyloid fibril formation and cytotoxicity by withdrawing Aβ oligomers from the amyloid pathway

(2011) Marta Marín-Argany et al.   BIOCHEMICAL JOURNAL

Amyloid β peptide oligomers directly activate NMDA receptors

(2011) Laura Texidó et al.   CELL CALCIUM

Amyloid beta peptide 1–42 disturbs intracellular calcium homeostasis through activation of GluN2B-containing N-methyl-d-aspartate receptors in cortical cultures

(2011) I.L. Ferreira et al.   CELL CALCIUM

Soluble A  Oligomers Inhibit Long-Term Potentiation through a Mechanism Involving Excessive Activation of Extrasynaptic NR2B-Containing NMDA Receptors

(2011) S. Li et al.   JOURNAL OF NEUROSCIENCE

Neuroprotective Effect of Neuropeptide Y against Beta-Amyloid 25–35 Toxicity in SH-SY5Y Neuroblastoma Cells Is Associated with Increased Neurotrophin Production

(2011) Nicoletta Croce et al.   Neurodegenerative Diseases

Subchronic memantine administration on spatial learning, exploratory activity, and nest-building in an APP/PS1 mouse model of Alzheimer’s disease

(2011) Mohammed Filali et al.   NEUROPHARMACOLOGY

Protective effect of systemic l-kynurenine and probenecid administration on behavioural and morphological alterations induced by toxic soluble amyloid beta (25–35) in rat hippocampus

(2010) Paul Carrillo-Mora et al.   BEHAVIOURAL BRAIN RESEARCH

Oligomerized Aβ25–35 induces increased tyrosine phosphorylation of NMDA receptor subunit 2A in rat hippocampal CA1 subfield

(2010) Gui-Mei Wu et al.   BRAIN RESEARCH

Amyloid β oligomers induce Ca2+ dysregulation and neuronal death through activation of ionotropic glutamate receptors

(2010) Elena Alberdi et al.   CELL CALCIUM

l-theanine protects the APP (Swedish mutation) transgenic SH-SY5Y cell against glutamate-induced excitotoxicity via inhibition of the NMDA receptor pathway

(2010) X. Di et al.   NEUROSCIENCE

Soluble Oligomers of Amyloid β Protein Facilitate Hippocampal Long-Term Depression by Disrupting Neuronal Glutamate Uptake

(2009) Shaomin Li et al.   NEURON

Memory and the NMDA Receptors

(2009) Fei Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Memantine protects rat cortical cultured neurons against β-amyloid-induced toxicity by attenuating tau phosphorylation

(2008) M. S. Song et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Specific Targeting of Pro-Death NMDA Receptor Signals with Differing Reliance on the NR2B PDZ Ligand

(2008) F. X. Soriano et al.   JOURNAL OF NEUROSCIENCE

Amyloid β peptide toxicity in differentiated PC12 cells: Calpain‐calpastatin, caspase, and membrane damage

(2008) Tali Vaisid et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Different protection of K252a and N-acetyl-L-cysteine against amyloid-β peptide-induced cortical neuron apoptosis involving inhibition of MLK3-MKK7-JNK3 signal cascades

(2008) Yan Xu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

A Comparative Study of β-Amyloid Peptides Aβ1-42 and Aβ25-35 Toxicity in Organotypic Hippocampal Slice Cultures

(2008) Rudimar Luiz Frozza et al.   NEUROCHEMICAL RESEARCH

Amyloid-β25–35 impairs memory and increases NO in the temporal cortex of rats

(2008) I. Daniel Limón et al.   NEUROSCIENCE RESEARCH

Amyloid β-peptide activates nuclear factor-κB through an N-methyl-D-aspartate signaling pathway in cultured cerebellar cells

(2007) E. M. Kawamoto et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The attenuating effect of memantine on staurosporine-, salsolinol- and doxorubicin-induced apoptosis in human neuroblastoma SH-SY5Y cells

(2007) D. Jantas et al.   NEUROCHEMISTRY INTERNATIONAL