Metformin enhances tamoxifen-mediated tumor growth inhibition in ER-positive breast carcinoma

Metformin-induced preferential killing of breast cancer initiating CD44+CD24-/low cells is sufficient to overcome primary resistance to trastuzumab in HER2+ human breast cancer xenografts

(2015) Sílvia Cufí et al.   Oncotarget

Response of Breast Cancer Cells and Cancer Stem Cells to Metformin and Hyperthermia Alone or Combined

(2014) Hyemi Lee et al.   PLoS One

Celecoxib alleviates tamoxifen-instigated angiogenic effects by ROS-dependent VEGF/VEGFR2 autocrine signaling

(2013) B N Prashanth Kumar et al.   BMC CANCER

Five or more years of adjuvant endocrine therapy in breast cancer: a meta-analysis of published randomised trials

(2013) Fausto Petrelli et al.   BREAST CANCER RESEARCH AND TREATMENT

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

(2013)   LANCET

Metformin Therapy and Risk of Cancer in Patients with Type 2 Diabetes: Systematic Review

(2013) Monica Franciosi et al.   PLoS One

Metformin in early breast cancer: a prospective window of opportunity neoadjuvant study

(2012) Saroj Niraula et al.   BREAST CANCER RESEARCH AND TREATMENT

Metformin and breast cancer risk: a meta-analysis and critical literature review

(2012) Nananda F. Col et al.   BREAST CANCER RESEARCH AND TREATMENT

Ras homolog gene family, member A promotes p53 degradation and vascular endothelial growth factor-dependent angiogenesis through an interaction with murine double minute 2 under hypoxic conditions

(2012) Ji Ma et al.   CANCER

The Links Between Insulin Resistance, Diabetes, and Cancer

(2012) Etan Orgel et al.   Current Diabetes Reports

Dual Effect of Metformin on Breast Cancer Proliferation in a Randomized Presurgical Trial

(2012) Bernardo Bonanni et al.   JOURNAL OF CLINICAL ONCOLOGY

Randomized Phase II Trial of Everolimus in Combination With Tamoxifen in Patients With Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Metastatic Breast Cancer With Prior Exposure to Aromatase Inhibitors: A GINECO Study

(2012) Thomas Bachelot et al.   JOURNAL OF CLINICAL ONCOLOGY

Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial

(2012) Christina Davies et al.   LANCET

Metformin inhibits breast cancer cell growth, colony formation and induces cell cycle arrest in vitro

(2011) Irina N. Alimova et al.   CELL CYCLE

Insulin-like growth factor-2 (IGF-2) activates estrogen receptor-α and -β via the IGF-1 and the insulin receptors in breast cancer cells

(2011) A. E. Richardson et al.   GROWTH FACTORS

Isolated and combined action of tamoxifen and metformin in wild-type, tamoxifen-resistant, and estrogen-deprived MCF-7 cells

(2010) Lev M. Berstein et al.   BREAST CANCER RESEARCH AND TREATMENT

Effectiveness of a patient- and practice-level colorectal cancer screening intervention in health plan members

(2010) Carmen Lewis et al.   CANCER

Long-Term Metformin Use Is Associated With Decreased Risk of Breast Cancer

(2010) M. Bodmer et al.   DIABETES CARE

Incorporating the antidiabetic drug metformin in HER2-positive breast cancer treated with neo-adjuvant chemotherapy and trastuzumab: an ongoing clinical-translational research experience at the Catalan Institute of Oncology

(2009) B. Martin-Castillo et al.   ANNALS OF ONCOLOGY

Effects of metformin on mammalian target of rapamycin in a mouse model of endometrial hyperplasia

(2009) Evrim Erdemoglu et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Metformin, insulin, breast cancer and more…

(2009) Lev M Berstein   Future Oncology

Metformin in Breast Cancer: Time for Action

(2009) Pamela J. Goodwin et al.   JOURNAL OF CLINICAL ONCOLOGY

Metformin and Pathologic Complete Responses to Neoadjuvant Chemotherapy in Diabetic Patients With Breast Cancer

(2009) Sao Jiralerspong et al.   JOURNAL OF CLINICAL ONCOLOGY

Meta-Analysis of Breast Cancer Outcomes in Adjuvant Trials of Aromatase Inhibitors Versus Tamoxifen

(2009) Mitch Dowsett et al.   JOURNAL OF CLINICAL ONCOLOGY

Insulin-Lowering Effects of Metformin in Women with Early Breast Cancer

(2008) Pamela J. Goodwin et al.   Clinical Breast Cancer