Hypoxia promotes Mycobacterium tuberculosis-specific up-regulation of granulysin in human T cells

The DosR Regulon Modulates Adaptive Immunity and Is Essential forMycobacterium tuberculosisPersistence

(2015) Smriti Mehra et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The impact of hypoxia on bacterial infection

(2015) Kirsten Schaffer et al.   FEBS Journal

Human Monocytes Undergo Functional Re-programming during Sepsis Mediated by Hypoxia-Inducible Factor-1α

(2015) Irina N. Shalova et al.   IMMUNITY

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

(2014) Michael Walch et al.   CELL

Delivering Three Punches to Knockout Intracellular Bacteria

(2014) Emilie Narni-Mancinelli et al.   CELL

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Beyond macrophages: the diversity of mononuclear cells in tuberculosis

(2014) Smita Srivastava et al.   IMMUNOLOGICAL REVIEWS

Mycobacterial Lipopeptides Elicit CD4+ CTLs in Mycobacterium tuberculosis-Infected Humans

(2014) M. Bastian et al.   JOURNAL OF IMMUNOLOGY

Interception of host angiogenic signalling limits mycobacterial growth

(2014) Stefan H. Oehlers et al.   NATURE

Role of TNF in the Altered Interaction of Dormant Mycobacterium tuberculosis with Host Macrophages

(2014) Uma S. Gautam et al.   PLoS One

Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas

(2014) M. A. Duque-Correa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Three-DimensionalIn VitroModels of Granuloma to Study Bacteria-Host Interactions, Drug-Susceptibility, and Resuscitation of Dormant Mycobacteria

(2014) Liam E. Fitzgerald et al.   Biomed Research International

Hypoxia Inducible Factor Stabilization As a Novel Strategy to Treat Anemia

(2013) S. Zhao et al.   CURRENT MEDICINAL CHEMISTRY

The Mycobacterium tuberculosis regulatory network and hypoxia

(2013) James E. Galagan et al.   NATURE

Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen

(2013) Andrew L Doedens et al.   NATURE IMMUNOLOGY

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

(2013) Philip M. Elks et al.   PLoS Pathogens

HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis

(2013) Elizabeth A. Berger et al.   PLoS Pathogens

Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function

(2012) Eóin N. McNamee et al.   IMMUNOLOGIC RESEARCH

Hypoxia Triggers the Expression of Human   Defensin 2 and Antimicrobial Activity against Mycobacterium tuberculosis in Human Macrophages

(2012) D. Nickel et al.   JOURNAL OF IMMUNOLOGY

HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis

(2012) Masaaki Higashiyama et al.   JOURNAL OF LEUKOCYTE BIOLOGY

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(2012) Sayma Rahman et al.   MOLECULAR MEDICINE

New pathways of protective and pathological host defense to mycobacteria

(2012) Tom H.M. Ottenhoff   TRENDS IN MICROBIOLOGY

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

Granulysin-Expressing CD4+ T Cells as Candidate Immune Marker for Tuberculosis during Childhood and Adolescence

(2011) Henrik Mueller et al.   PLoS One

Compartmentalization of Immune Responses in Human Tuberculosis

(2009) Sayma Rahman et al.   AMERICAN JOURNAL OF PATHOLOGY

Adaptation of Human CD4+ T Cells to Pathophysiological Hypoxia: A Transcriptome Analysis

(2009) T. GABER et al.   JOURNAL OF RHEUMATOLOGY

Biology and clinical relevance of granulysin

(2009) A. M. Krensky et al.   TISSUE ANTIGENS

Pharmacologic Augmentation of Hypoxia‐Inducible Factor–1α with Mimosine Boosts the Bactericidal Capacity of Phagocytes

(2008) Annelies S. Zinkernagel et al.   JOURNAL OF INFECTIOUS DISEASES

Critical Role of HIF-1α in Keratinocyte Defense against Bacterial Infection

(2008) Carole Peyssonnaux et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Enduring Hypoxic Response of Mycobacterium tuberculosis

(2008) Tige R. Rustad et al.   PLoS One