The impact of hypoxia on bacterial infection

HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals

(2014) Daniel Bandarra et al.   Disease Models & Mechanisms

Transmigrating Neutrophils Shape the Mucosal Microenvironment through Localized Oxygen Depletion to Influence Resolution of Inflammation

(2014) Eric L. Campbell et al.   IMMUNITY

HIF Transcription Factors, Inflammation, and Immunity

(2014) Asis Palazon et al.   IMMUNITY

Interception of host angiogenic signalling limits mycobacterial growth

(2014) Stefan H. Oehlers et al.   NATURE

Human oxygen sensing may have origins in prokaryotic elongation factor Tu prolyl-hydroxylation

(2014) John S. Scotti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

Hypoxia Modulates Infection of Epithelial Cells by Pseudomonas aeruginosa

(2013) Bettina Schaible et al.   PLoS One

Hypoxia Inducible Factor Signaling Modulates Susceptibility to Mycobacterial Infection via a Nitric Oxide Dependent Mechanism

(2013) Philip M. Elks et al.   PLoS Pathogens

HIF-1α Is Essential for Effective PMN Bacterial Killing, Antimicrobial Peptide Production and Apoptosis in Pseudomonas aeruginosa Keratitis

(2013) Elizabeth A. Berger et al.   PLoS Pathogens

Hypoxia Increases Antibiotic Resistance in Pseudomonas aeruginosa through Altering the Composition of Multidrug Efflux Pumps

(2012) Bettina Schaible et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model

(2012) Peter Georgiev et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection

(2012) Cheryl Y. M. Okumura et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

EGL-9 Controls C. elegans Host Defense Specificity through Prolyl Hydroxylation-Dependent and -Independent HIF-1 Pathways

(2012) Lyly G. Luhachack et al.   PLoS Pathogens

A Myeloid Hypoxia-inducible Factor 1α-Krüppel-like Factor 2 Pathway Regulates Gram-positive Endotoxin-mediated Sepsis

(2011) Ganapati H. Mahabeleshwar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia and Inflammation

(2011) Holger K. Eltzschig et al.   NEW ENGLAND JOURNAL OF MEDICINE

The Hydroxylase Inhibitor Dimethyloxallyl Glycine Attenuates Endotoxic Shock Via Alternative Activation of Macrophages and IL-10 Production by B1 Cells

(2011) Emily Hams et al.   SHOCK

In vivo Hypoxia and a Fungal Alcohol Dehydrogenase Influence the Pathogenesis of Invasive Pulmonary Aspergillosis

(2011) Nora Grahl et al.   PLoS Pathogens

Hypoxia-Inducible Factor Signaling Provides Protection in Clostridium difficile-Induced Intestinal Injury

(2010) Simon A. Hirota et al.   GASTROENTEROLOGY

Modulation of Shigella virulence in response to available oxygen in vivo

(2010) Benoit Marteyn et al.   NATURE

Hypoxia: an alarm signal during intestinal inflammation

(2010) Sean P. Colgan et al.   Nature Reviews Gastroenterology & Hepatology

Ancient Atmospheres and the Evolution of Oxygen Sensing Via the Hypoxia-Inducible Factor in Metazoans

(2010) Cormac T. Taylor et al.   PHYSIOLOGY

Activation of Hypoxia Inducible Factor 1 Is a General Phenomenon in Infections with Human Pathogens

(2010) Nadine Werth et al.   PLoS One

C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1-Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1

(2010) Zhiyong Shao et al.   PLoS Pathogens

The Role of NF-κB in Hypoxia-Induced Gene Expression

(2009) Cormac T. Taylor et al.   Annals of the New York Academy of Sciences

Hypoxia: a window intoMycobacterium tuberculosislatency

(2009) Tige R. Rustad et al.   CELLULAR MICROBIOLOGY

Hypoxia and the Hypoxic Response Pathway Protect against Pore-Forming Toxins in C. elegans

(2009) Audrey Bellier et al.   PLoS Pathogens

Hypoxia-Independent Activation of HIF-1 by Enterobacteriaceae and Their Siderophores

(2008) Hanna Hartmann et al.   GASTROENTEROLOGY

Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates

(2008) L. E. Via et al.   INFECTION AND IMMUNITY

Pharmacologic Augmentation of Hypoxia‐Inducible Factor–1α with Mimosine Boosts the Bactericidal Capacity of Phagocytes

(2008) Annelies S. Zinkernagel et al.   JOURNAL OF INFECTIOUS DISEASES

Critical Role of HIF-1α in Keratinocyte Defense against Bacterial Infection

(2008) Carole Peyssonnaux et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL