MicroRNA Dysregulation in Cystic Fibrosis

Developmental control of CFTR: from bioinformatics to novel therapeutic approaches

(2015) C. M. Greene et al.   EUROPEAN RESPIRATORY JOURNAL

Modulation of the Unfolded Protein Response Is the Core of MicroRNA-122-Involved Sensitivity to Chemotherapy in Hepatocellular Carcinoma

(2015) Fu Yang et al.   NEOPLASIA

A New Player in the Game: Epithelial Cathepsin S in Early Cystic Fibrosis Lung Disease

(2014) Marcus A. Mall et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

miR-31 Dysregulation in Cystic Fibrosis Airways Contributes to Increased Pulmonary Cathepsin S Production

(2014) Sinéad Weldon et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Expression of microRNA-93 and Interleukin-8 duringPseudomonas aeruginosa–Mediated Induction of Proinflammatory Responses

(2014) Enrica Fabbri et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

(2014) K. Pohl et al.   BLOOD

Emerging Role of MicroRNAs and Long Noncoding RNAs in Respiratory Disease

(2014) Richard Booton et al.   CHEST

Transcription factors and miRNAs that regulate fetal to adult CFTR expression change are new targets for cystic fibrosis

(2014) V. Viart et al.   EUROPEAN RESPIRATORY JOURNAL

Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibitor of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression

(2014) Felice Amato et al.   Biomed Research International

Common features of microRNA target prediction tools

(2014) Sarah M. Peterson et al.   Frontiers in Genetics

miR-199a-5p Silencing Regulates the Unfolded Protein Response in Chronic Obstructive Pulmonary Disease and α1-Antitrypsin Deficiency

(2013) Tidi Hassan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Post-Transcriptional Regulation of Cystic Fibrosis Transmembrane Conductance Regulator Expression and Function by MicroRNAs

(2013) Shyam Ramachandran et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

mmu-miR-702 functions as an anti-apoptotic mirtron by mediating ATF6 inhibition in mice

(2013) Wei-guang Zhang et al.   GENE

Analysis of CDS-located miRNA target sites suggests that they can effectively inhibit translation

(2013) J. Hausser et al.   GENOME RESEARCH

Targeting miRNA-based medicines to cystic fibrosis airway epithelial cells using nanotechnology

(2013) Sally-Ann Cryan et al.   International Journal of Nanomedicine

Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by MicroRNA-145, -223, and -494 Is Altered in  F508 Cystic Fibrosis Airway Epithelium

(2013) I. K. Oglesby et al.   JOURNAL OF IMMUNOLOGY

Adult-specific functions of animal microRNAs

(2013) Kailiang Sun et al.   NATURE REVIEWS GENETICS

Gene Mutation in MicroRNA Target Sites of CFTR Gene: A Novel Pathogenetic Mechanism in Cystic Fibrosis?

(2013) Felice Amato et al.   PLoS One

Role of microRNAs in Lung Development and Pulmonary Diseases

(2013) Roberto Sessa et al.   Pulmonary Circulation

The CFTR and ENaC debate: how important is ENaC in CF lung disease?

(2012) James F. Collawn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Therapeutic modulation of miRNA for the treatment of proinflammatory lung diseases

(2012) Tidi Hassan et al.   Expert Review of Anti-Infective Therapy

MicroRNA-30c-2* limits expression of proadaptive factor XBP1 in the unfolded protein response

(2012) Andrew E. Byrd et al.   JOURNAL OF CELL BIOLOGY

Innate immunity in cystic fibrosis lung disease

(2012) D. Hartl et al.   Journal of Cystic Fibrosis

MiR-101 and miR-144 Regulate the Expression of the CFTR Chloride Channel in the Lung

(2012) Fatemat Hassan et al.   PLoS One

A microRNA network regulates expression and biosynthesis of wild-type and  F508 mutant cystic fibrosis transmembrane conductance regulator

(2012) S. Ramachandran et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene

(2011) Austin E. Gillen et al.   BIOCHEMICAL JOURNAL

A trio of microRNAs that control Toll-like receptor signalling

(2011) S. R. Quinn et al.   INTERNATIONAL IMMUNOLOGY

Abnormal Trafficking and Degradation of TLR4 Underlie the Elevated Inflammatory Response in Cystic Fibrosis

(2011) E. M. Bruscia et al.   JOURNAL OF IMMUNOLOGY

Synergistic Post-Transcriptional Regulation of the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) by miR-101 and miR-494 Specific Binding

(2011) Francesca Megiorni et al.   PLoS One

Functional study of elafin cleaved by Pseudomonas aeruginosa metalloproteinases

(2010) Nicolas Guyot et al.   BIOLOGICAL CHEMISTRY

Pulmonary Proteases in the Cystic Fibrosis Lung Induce Interleukin 8 Expression from Bronchial Epithelial Cells via a Heme/Meprin/Epidermal Growth Factor Receptor/Toll-like Receptor Pathway

(2010) Sonya Cosgrove et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

miR-126 Is Downregulated in Cystic Fibrosis Airway Epithelial Cells and Regulates TOM1 Expression

(2010) Irene K. Oglesby et al.   JOURNAL OF IMMUNOLOGY

Dysfunctional cystic fibrosis transmembrane conductance regulator inhibits phagocytosis of apoptotic cells with proinflammatory consequences

(2009) R. William Vandivier et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Blood Monocytes: Development, Heterogeneity, and Relationship with Dendritic Cells

(2009) Cedric Auffray et al.   Annual Review of Immunology

Alveolar macrophages and CC chemokines are increased in children with cystic fibrosis

(2009) S. Brennan et al.   EUROPEAN RESPIRATORY JOURNAL

Disease-causing Mutations in the Cystic Fibrosis Transmembrane Conductance Regulator Determine the Functional Responses of Alveolar Macrophages

(2009) Ludmila V. Deriy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping the Lung Proteome in Cystic Fibrosis

(2009) Sina A. Gharib et al.   JOURNAL OF PROTEOME RESEARCH

Macrophages Directly Contribute to the Exaggerated Inflammatory Response in Cystic Fibrosis Transmembrane Conductance Regulator−/−Mice

(2008) Emanuela M. Bruscia et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

The phagocytes: neutrophils and monocytes

(2008) D. C. Dale et al.   BLOOD

Toll-like receptors as therapeutic targets in cystic fibrosis

(2008) Catherine M Greene et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE

Alterations in immune response and PPAR/LXR regulation in cystic fibrosis macrophages

(2007) Charlotte Andersson et al.   Journal of Cystic Fibrosis