Exploitation of a Very Small Peptide Nucleic Acid as a New Inhibitor of miR-509-3p Involved in the Regulation of Cystic Fibrosis Disease-Gene Expression

Effects of Hypoxanthine Substitution in Peptide Nucleic Acids Targeting KRAS2 Oncogenic mRNA Molecules: Theory and Experiment

(2013) Jeffrey M. Sanders et al.   JOURNAL OF PHYSICAL CHEMISTRY B

MicroRNAs with a role in gene regulation and in human diseases

(2013) Sami Ullah et al.   MOLECULAR BIOLOGY REPORTS

PNA as a potential modulator of COL7A1 gene expression in dominant dystrophic epidermolysis bullosa: a physico-chemical study

(2013) Jussara Amato et al.   Molecular BioSystems

Design, synthesis and biochemical investigation, by in vitro luciferase reporter system, of peptide nucleic acids as new inhibitors of miR-509-3p involved in the regulation of cystic fibrosis disease-gene expression

(2013) Felice Amato et al.   MedChemComm

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Cellular Uptakes, Biostabilities and Anti-miR-210 Activities of Chiral Arginine-PNAs in Leukaemic K562 Cells

(2012) Alex Manicardi et al.   CHEMBIOCHEM

PNA-based microRNA inhibitors elicit anti-inflammatory effects in microglia cells

(2012) Peter N. Brown et al.   CHEMICAL COMMUNICATIONS

Developing MicroRNA Therapeutics

(2012) Eva van Rooij et al.   CIRCULATION RESEARCH

MicroRNA therapeutics for cardiovascular disease: opportunities and obstacles

(2012) Eva van Rooij et al.   NATURE REVIEWS DRUG DISCOVERY

MicroRNAs in Common Human Diseases

(2012) Yu Li et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

microRNA regulation of expression of the cystic fibrosis transmembrane conductance regulator gene

(2011) Austin E. Gillen et al.   BIOCHEMICAL JOURNAL

Targeting G-Quadruplex Structure in the Human c-Kit Promoter with Short PNA Sequences

(2011) Jussara Amato et al.   BIOCONJUGATE CHEMISTRY

PNA-based artificial nucleases as antisense and anti-miRNA oligonucleotide agents

(2011) M. Gaglione et al.   Molecular BioSystems

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

Silencing of microRNA families by seed-targeting tiny LNAs

(2011) Susanna Obad et al.   NATURE GENETICS

Chemical structure requirements and cellular targeting of microRNA-122 by peptide nucleic acids anti-miRs

(2011) Adrian G. Torres et al.   NUCLEIC ACIDS RESEARCH

The Promise of MicroRNA Replacement Therapy

(2010) A. G. Bader et al.   CANCER RESEARCH

Peptide Nucleic Acids (PNA) in Chemical Biology and Drug Discovery

(2010) Peter E. Nielsen   CHEMISTRY & BIODIVERSITY

Molecular diagnostics: between chips and customized medicine

(2010) Giuseppe Castaldo et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Stress-dependent cardiac remodeling occurs in the absence of microRNA-21 in mice

(2010) David M. Patrick et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular Dynamics of Potential rRNA Binders: Single-Stranded Nucleic Acids and Some Analogues

(2010) Joanna Panecka et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Efficient inhibition of miR-155 function in vivo by peptide nucleic acids

(2010) Martin M. Fabani et al.   NUCLEIC ACIDS RESEARCH

Conformational analysis of nucleic acids revisited: Curves+

(2009) R. Lavery et al.   NUCLEIC ACIDS RESEARCH

Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection

(2009) R. E. Lanford et al.   SCIENCE

Hybridization of short complementary PNAs to G-quadruplex forming oligonucleotides: An electrospray mass spectrometry study

(2008) Jussara Amato et al.   BIOPOLYMERS

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE