The CFTR and ENaC debate: how important is ENaC in CF lung disease?

Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung

(2011) Ahmed Lazrak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Transgenic hCFTR expression fails to correct β-ENaC mouse lung disease

(2011) B. R. Grubb et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Epithelial sodium channels (ENaC) are uniformly distributed on motile cilia in the oviduct and the respiratory airways

(2011) Yehoshua Enuka et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Human cystic fibrosis airway epithelia have reduced Cl- conductance but not increased Na+ conductance

(2011) O. A. Itani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The  F508 Mutation Causes CFTR Misprocessing and Cystic Fibrosis-Like Disease in Pigs

(2011) L. S. Ostedgaard et al.   Science Translational Medicine

Loss of Anion Transport without Increased Sodium Absorption Characterizes Newborn Porcine Cystic Fibrosis Airway Epithelia

(2010) Jeng-Haur Chen et al.   CELL

The Cystic Fibrosis Transmembrane Conductance Regulator Impedes Proteolytic Stimulation of the Epithelial Na+Channel

(2010) Martina Gentzsch et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Airway Surface Liquid Volume Regulation Determines Different Airway Phenotypes in Liddle Compared with βENaC-overexpressing Mice

(2010) Marcus A. Mall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at Birth

(2010) D. A. Stoltz et al.   Science Translational Medicine

Role of the amiloride-sensitive epithelial Na+channel in the pathogenesis and as a therapeutic target for cystic fibrosis lung disease

(2008) Marcus A. Mall   EXPERIMENTAL PHYSIOLOGY

Cystic fibrosis: impaired bicarbonate secretion and mucoviscidosis

(2008) Paul M Quinton   LANCET