A neutrophil intrinsic impairment affecting Rab27a and degranulation in cystic fibrosis is corrected by CFTR potentiator therapy

Rab27a Regulates Exocytosis of Tertiary and Specific Granules in Human Neutrophils

(2014) M. J. Herrero-Turrion et al.   JOURNAL OF IMMUNOLOGY

Regulation of Cystic Fibrosis Transmembrane Conductance Regulator by MicroRNA-145, -223, and -494 Is Altered in  F508 Cystic Fibrosis Airway Epithelium

(2013) I. K. Oglesby et al.   JOURNAL OF IMMUNOLOGY

Cystic Fibrosis Transmembrane Conductance Regulator Recruitment to Phagosomes in Neutrophils

(2013) Yun Zhou et al.   Journal of Innate Immunity

Regulation of vesicular trafficking and leukocyte function by Rab27 GTPases and their effectors

(2013) Sergio Daniel Catz   JOURNAL OF LEUKOCYTE BIOLOGY

Absence of the cystic fibrosis transmembrane regulator (Cftr ) from myeloid-derived cells slows resolution of inflammation and infection

(2012) T. L. Bonfield et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Enhancement of alveolar epithelial sodium channel activity with decreased cystic fibrosis transmembrane conductance regulator expression in mouse lung

(2011) Ahmed Lazrak et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Nebulized Hypertonic Saline Decreases IL-8 in Sputum of Patients with Cystic Fibrosis

(2011) Emer P. Reeves et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Cystic Fibrosis Neutrophil: A Specialized Yet Potentially Defective Cell

(2011) Elaine Hayes et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Inhibitory effects of lactoferrin on biofilm formation in clinical isolates of Pseudomonas aeruginosa

(2011) Hiroyuki Kamiya et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

A CFTR Potentiator in Patients with Cystic Fibrosis and theG551DMutation

(2011) Bonnie W. Ramsey et al.   NEW ENGLAND JOURNAL OF MEDICINE

Intracellular GTP level determines cell's fate toward differentiation and apoptosis

(2011) Azadeh Meshkini et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

RNA interference against CFTR affects HL60-derived neutrophil microbicidal function

(2010) Ryan W. Bonvillain et al.   FREE RADICAL BIOLOGY AND MEDICINE

α-1 Antitrypsin regulates human neutrophil chemotaxis induced by soluble immune complexes and IL-8

(2010) David A. Bergin et al.   JOURNAL OF CLINICAL INVESTIGATION

In Cystic Fibrosis Homozygotes and Heterozygotes, Neutrophil Apoptosis Is Delayed and Modulated by Diamide or Roscovitine: Evidence for an Innate Neutrophil Disturbance

(2010) Sandra Moriceau et al.   Journal of Innate Immunity

CFTR-mediated halide transport in phagosomes of human neutrophils

(2010) Richard G. Painter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Effect of VX-770 in Persons with Cystic Fibrosis and the G551D-CFTRMutation

(2010) Frank J. Accurso et al.   NEW ENGLAND JOURNAL OF MEDICINE

Coronin-1 Is Associated with Neutrophil Survival and Is Cleaved during Apoptosis: Potential Implication in Neutrophils from Cystic Fibrosis Patients

(2009) S. Moriceau et al.   JOURNAL OF IMMUNOLOGY

LL-37 Complexation with Glycosaminoglycans in Cystic Fibrosis Lungs Inhibits Antimicrobial Activity, Which Can Be Restored by Hypertonic Saline

(2009) G. Bergsson et al.   JOURNAL OF IMMUNOLOGY

Comparing two small samples with an unstable, treatment-independent baseline

(2009) Skirmantas Janušonis   JOURNAL OF NEUROSCIENCE METHODS

Rescue of CF airway epithelial cell function in vitro by a CFTR potentiator, VX-770

(2009) F. Van Goor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rab27a and Rab27b Regulate Neutrophil Azurophilic Granule Exocytosis and NADPH oxidase Activity by Independent Mechanisms

(2009) Jennifer L. Johnson et al.   TRAFFIC

Evidence for direct CFTR inhibition by CFTRinh-172 based on Arg347mutagenesis

(2008) Emanuela Caci et al.   BIOCHEMICAL JOURNAL

The role of chloride anion and CFTR in killing of Pseudomonas aeruginosa by normal and CF neutrophils

(2008) R. G. Painter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Assessment of the CFTR and ENaC association

(2008) Bakhrom K. Berdiev et al.   Molecular BioSystems

A Feeder-Free and Efficient Production of Functional Neutrophils from Human Embryonic Stem Cells

(2008) Koichi Saeki et al.   STEM CELLS

The Rab27a Effectors JFC1/Slp1 and Munc13-4 Regulate Exocytosis of Neutrophil Granules

(2008) Agnieszka A. Brzezinska et al.   TRAFFIC