The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation
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Title
The adaptor protein LAT serves as an integration node for signaling pathways that drive T cell activation
Authors
Keywords
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Journal
Wiley Interdisciplinary Reviews-Systems Biology and Medicine
Volume 5, Issue 1, Pages 101-110
Publisher
Wiley
Online
2012-11-14
DOI
10.1002/wsbm.1194
References
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Related references
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- (2012) C.-w. Ou-Yang et al. MOLECULAR AND CELLULAR BIOLOGY
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- Modeling and Simulation of Aggregation of Membrane Protein LAT with Molecular Variability in the Number of Binding Sites for Cytosolic Grb2-SOS1-Grb2
- (2012) Ambarish Nag et al. PLoS One
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- (2011) Meirav Sela et al. EMBO JOURNAL
- Conditional deletion of SLP-76 in mature T cells abrogates peripheral immune responses
- (2011) Gregory F. Wu et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Role of Two Adaptor Molecules SLP-76 and LAT in the PI3K Signaling Pathway in Activated T Cells
- (2011) E. K. Shim et al. JOURNAL OF IMMUNOLOGY
- Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation
- (2011) L. Balagopalan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cooperative interactions at the SLP-76 complex are critical for actin polymerization
- (2010) Mira Barda-Saad et al. EMBO JOURNAL
- Multiple pathways leading from the T-cell antigen receptor to the actin cytoskeleton network
- (2010) Barak Reicher et al. FEBS LETTERS
- The Role of the LAT–PLC-γ1 Interaction in T Regulatory Cell Function
- (2010) Mariana I. Chuck et al. JOURNAL OF IMMUNOLOGY
- T-Cell Receptor Microclusters Critical for T-Cell Activation Are Formed Independently of Lipid Raft Clustering
- (2010) A. Hashimoto-Tane et al. MOLECULAR AND CELLULAR BIOLOGY
- Molecular mechanisms in signal transduction at the membrane
- (2010) Jay T Groves et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Coordination of Receptor Signaling in Multiple Hematopoietic Cell Lineages by the Adaptor Protein SLP-76
- (2010) M. S. Jordan et al. Cold Spring Harbor Perspectives in Biology
- Lipid Signaling in T-Cell Development and Function
- (2010) Y. H. Huang et al. Cold Spring Harbor Perspectives in Biology
- Mediation of T-Cell Activation by Actin Meshworks
- (2010) P. Beemiller et al. Cold Spring Harbor Perspectives in Biology
- T Cell Activation
- (2009) Jennifer E. Smith-Garvin et al. Annual Review of Immunology
- Digital Signaling and Hysteresis Characterize Ras Activation in Lymphoid Cells
- (2009) Jayajit Das et al. CELL
- Loss of the LAT Adaptor Converts Antigen-Responsive T Cells into Pathogenic Effectors that Function Independently of the T Cell Receptor
- (2009) Michael Mingueneau et al. IMMUNITY
- Calcium signaling in the development and function of T-lineage cells
- (2009) Masatsugu Oh-hora IMMUNOLOGICAL REVIEWS
- T-cell receptor proximal signaling via the Src-family kinases, Lck and Fyn, influences T-cell activation, differentiation, and tolerance
- (2009) Robert J. Salmond et al. IMMUNOLOGICAL REVIEWS
- Endocytic events in TCR signaling: focus on adapters in microclusters
- (2009) Lakshmi Balagopalan et al. IMMUNOLOGICAL REVIEWS
- The coreceptor CD2 uses plasma membrane microdomains to transduce signals in T cells
- (2009) Yoshihisa Kaizuka et al. JOURNAL OF CELL BIOLOGY
- PI3 kinase function is vital for the function but not formation of LAT-mediated signaling complexes
- (2009) Noemi Cruz-Orcutt et al. MOLECULAR IMMUNOLOGY
- TCR and Lat are expressed on separate protein islands on T cell membranes and concatenate during activation
- (2009) Björn F Lillemeier et al. NATURE IMMUNOLOGY
- The NF- B Family of Transcription Factors and Its Regulation
- (2009) A. Oeckinghaus et al. Cold Spring Harbor Perspectives in Biology
- CD4 T cells: fates, functions, and faults
- (2008) J. Zhu et al. BLOOD
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