The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal
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Title
The huntingtin N17 domain is a multifunctional CRM1 and Ran-dependent nuclear and cilial export signal
Authors
Keywords
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Journal
HUMAN MOLECULAR GENETICS
Volume 22, Issue 7, Pages 1383-1394
Publisher
Oxford University Press (OUP)
Online
2013-01-09
DOI
10.1093/hmg/dds554
References
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- The Tpr protein regulates export of mRNAs with retained introns that traffic through the Nxf1 pathway
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- Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates
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- (2008) Paul R. Clarke et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
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