The nucleolus, an ally, and an enemy of cancer cells

Cross talk between TP53 and c-Myc in the pathophysiology of Diamond-Blackfan anemia: Evidence from RPL11-deficient in vivo and in vitro models

(2018) Anirban Chakraborty et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

New Roles for the Nucleolus in Health and Disease

(2018) Lorena Núñez Villacís et al.   BIOESSAYS

Prevention of doxorubicin (DOX)-induced genotoxicity and cardiotoxicity: Effect of plant derived small molecule indole-3-carbinol (I3C) on oxidative stress and inflammation

(2018) Subhadip Hajra et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibition of PI3K/Akt/mTOR pathway by apigenin induces apoptosis and autophagy in hepatocellular carcinoma cells

(2018) Jiali Yang et al.   BIOMEDICINE & PHARMACOTHERAPY

Development of dual casein kinase 1δ/1ε (CK1δ/ε) inhibitors for treatment of breast cancer

(2018) Andrii Monastyrskyi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Diagnostic and prognostic implications of ribosomal protein transcript expression patterns in human cancers

(2018) James M. Dolezal et al.   BMC CANCER

Axonal excitability changes and acute symptoms of oxaliplatin treatment: In vivo evidence for slowed sodium channel inactivation

(2018) Rikke Heide et al.   CLINICAL NEUROPHYSIOLOGY

HMGB proteins involved in TOR signaling as general regulators of cell growth by controlling ribosome biogenesis

(2018) A. Vizoso-Vázquez et al.   CURRENT GENETICS

Ribosome biogenesis and cancer: basic and translational challenges

(2018) Xosé R. Bustelo et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The EGF/Ras pathway controls growth in Drosophila via ribosomal RNA synthesis

(2018) Shrivani Sriskanthadevan-Pirahas et al.   DEVELOPMENTAL BIOLOGY

A Systematic Review of Herbal Medicine for Chemotherapy Induced Peripheral Neuropathy

(2018) Hyeonseok Noh et al.   Evidence-based Complementary and Alternative Medicine

On the relationship status for Arf and NPM1 - it's complicated

(2018) Diana M. Mitrea et al.   FEBS Journal

Identification of a novel nucleophosmin-interaction motif in the tumor suppressor p14arf

(2018) Enrico Luchinat et al.   FEBS Journal

Protective Effect of D-Methionine on Body Weight Loss, Anorexia, and Nephrotoxicity in Cisplatin-Induced Chronic Toxicity in Rats

(2018) Ming-Tai Lin et al.   INTEGRATIVE CANCER THERAPIES

Glaucocalyxin A induces G2/M cell cycle arrest and apoptosis through the PI3K/Akt pathway in human bladder cancer cells

(2018) Wenfeng Lin et al.   International Journal of Biological Sciences

Identification and validation nucleolin as a target of curcumol in nasopharyngeal carcinoma cells

(2018) Juan Wang et al.   Journal of Proteomics

Oxaliplatin-induced changes in expression of transient receptor potential channels in the dorsal root ganglion as a neuropathic mechanism for cold hypersensitivity

(2018) Akiko Chukyo et al.   NEUROPEPTIDES

Nucleolus as an emerging hub in maintenance of genome stability and cancer pathogenesis

(2018) Mikael S. Lindström et al.   ONCOGENE

Abnormal Expression of PICT-1 and Its Codon 389 Polymorphism Is a Risk Factor for Human Endometrial Cancer

(2018) Masafumi Yoshimoto et al.   ONCOLOGY

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

(2018) Luis A. Carvajal et al.   Science Translational Medicine

Neurotoxic effect of oxaliplatin: Comparison with its oxalate-free analogue cis-[PtII(1R,2R-DACH)(3-acetoxy-1,1-cyclobutanedicarboxylato)] (LLC-1402) in mice

(2018) Anamaria Falcão Pereira et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Starvation, Stress Resistance, and Cancer

(2018) Roberta Buono et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Ribosomal protein L18 is an essential factor that promote rice stripe virus accumulation in small brown planthopper

(2018) Shuo Li et al.   VIRUS RESEARCH

Transcription factor FoxM1 is the downstream target of c-Myc and contributes to the development of prostate cancer

(2018) Huafeng Pan et al.   World Journal of Surgical Oncology

Butein activates p53 in hepatocellular carcinoma cells via blocking MDM2-mediated ubiquitination

(2018) Yuanfeng Zhou et al.   OncoTargets and Therapy

Nucleolin and ErbB2 inhibition reduces tumorigenicity of ErbB2-positive breast cancer

(2018) Eya Wolfson et al.   Cell Death & Disease

Nucleolar TRF2 attenuated nucleolus stress-induced HCC cell-cycle arrest by altering rRNA synthesis

(2018) Fuwen Yuan et al.   Cell Death & Disease

miR-126 suppresses epithelial-to-mesenchymal transition and metastasis by targeting PI3K/AKT/Snail signaling of lung cancer cells

(2018) Zhijun Jia et al.   Oncology Letters

A small molecule inhibitor of Rheb selectively targets mTORC1 signaling

(2018) Sarah J. Mahoney et al.   Nature Communications

Possible Mechanisms of the Prevention of Doxorubicin Toxicity by Cichoric Acid—Antioxidant Nutrient

(2018) Agata Jabłońska-Trypuć et al.   Nutrients

Enhanced skeletal muscle ribosome biogenesis, yet attenuated mTORC1 and ribosome biogenesis-related signalling, following short-term concurrent versus single-mode resistance training

(2018) Jackson J. Fyfe et al.   Scientific Reports

Prohibitin 2 localizes in nucleolus to regulate ribosomal RNA transcription and facilitate cell proliferation in RD cells

(2018) Zilong Zhou et al.   Scientific Reports

Shikonin exerts antitumor activity in Burkitt’s lymphoma by inhibiting C-MYC and PI3K/AKT/mTOR pathway and acts synergistically with doxorubicin

(2018) Fan Ni et al.   Scientific Reports

Small-Molecule Targeting of RNA Polymerase I Activates a Conserved Transcription Elongation Checkpoint

(2018) Ting Wei et al.   Cell Reports

Replication Study: Transcriptional amplification in tumor cells with elevated c-Myc

(2018) L Michelle Lewis et al.   eLife

The Multiple Functions of the Nucleolus in Plant Development, Disease and Stress Responses

(2018) Natalia O. Kalinina et al.   Frontiers in Plant Science

Phosphorylation of Ribosomal Protein RPS6 Integrates Light Signals and Circadian Clock Signals

(2018) Ramya Enganti et al.   Frontiers in Plant Science

Plant Nucleolar Stress Response, a New Face in the NAC-Dependent Cellular Stress Responses

(2018) Iwai Ohbayashi et al.   Frontiers in Plant Science

Targeting mTORC1/2 Complexes Inhibit Tumorigenesis and Enhance Sensitivity to 5-Flourouracil (5-FU) in Hepatocellular Carcinoma: A Preclinical Study of mTORC1/2-Targeted Therapy in Hepatocellular Carcinoma (HCC)

(2018) Yu Zhang et al.   MEDICAL SCIENCE MONITOR

Qianlie Xiaozheng Decoction Induces Autophagy in Human Prostate Cancer Cells via Inhibition of the Akt/mTOR Pathway

(2018) Yuehua Xu et al.   Frontiers in Pharmacology

The ribosome, (slow) beating heart of cancer (stem) cell

(2018) Amandine Bastide et al.   Oncogenesis

MDM2 Overexpression Modulates the Angiogenesis-Related Gene Expression Profile of Prostate Cancer Cells

(2018) Thiagarajan Venkatesan et al.   Cells

Conserved nucleolar stress at the onset of cell death

(2017) Pierre Golstein   FEBS Journal

Mitochondrial catalase induces cells transformation through nucleolin-dependent Cox-2 mRNA stabilization

(2017) Xin Liao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma

(2017) Isabel J.F. Hofman et al.   HAEMATOLOGICA

Molecular Mechanisms of Cardiotoxicity: A Review on Major Side-effect of Doxorubicin

(2017) M Mobaraki et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability

(2017) Yonghui Yu et al.   INTERNATIONAL JOURNAL OF CANCER

The Nucleolus: In Genome Maintenance and Repair

(2017) Maria Tsekrekou et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Ribosomal Proteins Control or Bypass p53 during Nucleolar Stress

(2017) Annapina Russo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of uL3 in Multidrug Resistance in p53-Mutated Lung Cancer Cells

(2017) Annapina Russo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nucleophosmin Regulates Intracellular Oxidative Stress Homeostasis via Antioxidant PRDX6

(2017) Guo-Yan Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Contribution of nucleophosmin overexpression to multidrug resistance in breast carcinoma

(2017) Siying Chen et al.   JOURNAL OF DRUG TARGETING

Sulforaphane and Epigallocatechin Gallate Restore Estrogen Receptor Expression by Modulating Epigenetic Events in the Breast Cancer Cell Line MDA-MB-231: A Systematic Review and Meta-Analysis

(2017) Vincenza Gianfredi et al.   Journal of Nutrigenetics and Nutrigenomics

Proteomic profiling reveals DNA damage, nucleolar and ribosomal stress are the main responses to oxaliplatin treatment in cancer cells

(2017) Tomas Ozdian et al.   Journal of Proteomics

NOTCH1-mutated chronic lymphocytic leukemia cells are characterized by a MYC-related overexpression of nucleophosmin 1 and ribosome-associated components

(2017) F Pozzo et al.   LEUKEMIA

Nucleostemin silencing induces differentiation and potentiates all- trans -retinoic acid effects in human acute promyelocytic leukemia NB4 cells via autophagy

(2017) Aila Fakhimahmadi et al.   LEUKEMIA RESEARCH

NRF2 Is a Major Target of ARF in p53-Independent Tumor Suppression

(2017) Delin Chen et al.   MOLECULAR CELL

Differing tumor-suppressor functions of Arf and p53 in murine basal cell carcinoma initiation and progression

(2017) G Y Wang et al.   ONCOGENE

Ribosomal protein S15a promotes tumor angiogenesis via enhancing Wnt/β-catenin-induced FGF18 expression in hepatocellular carcinoma

(2017) Pengyi Guo et al.   ONCOGENE

Silencing of Ribosomal Protein L34 (RPL34) Inhibits the Proliferation and Invasion of Esophageal Cancer Cells

(2017) Huijie Fan et al.   ONCOLOGY RESEARCH

Upregulated expression of Nucleostemin/GNL3 is associated with poor prognosis and Sorafenib Resistance in Hepatocellular Carcinoma

(2017) Lu Hua et al.   PATHOLOGY RESEARCH AND PRACTICE

snoRNA and piRNA expression levels modified by tobacco use in women with lung adenocarcinoma

(2017) Natasha Andressa Nogueira Jorge et al.   PLoS One

Early nucleolar disorganization in Dictyostelium cell death

(2017) M F Luciani et al.   Cell Death & Disease

MYC-family protein overexpression and prominent nucleolar formation represent prognostic indicators and potential therapeutic targets for aggressive high-MKI neuroblastomas: a report from the children’s oncology group

(2017) Risa Niemas-Teshiba et al.   Oncotarget

Undermining ribosomal RNA transcription in both the nucleolus and mitochondrion: an offbeat approach to target MYC-driven cancer

(2017) Stefano Rossetti et al.   Oncotarget

SNORD47, a box C/D snoRNA, suppresses tumorigenesis in glioblastoma

(2017) Bin Xu et al.   Oncotarget

MicroRNA-7641 is a regulator of ribosomal proteins and a promising targeting factor to improve the efficacy of cancer therapy

(2017) Abu Musa Md. Talimur Reza et al.   Scientific Reports

Ribosomal DNA copy number amplification and loss in human cancers is linked to tumor genetic context, nucleolus activity, and proliferation

(2017) Meng Wang et al.   PLoS Genetics

The uS8, uS4, eS31, and uL14 Ribosomal Protein Genes Are Dysregulated in Nasopharyngeal Carcinoma Cell Lines

(2017) Edmund Ui-Hang Sim et al.   Biomed Research International

Low frequency mutations in ribosomal proteins RPL10 and RPL5 in multiple myeloma

(2017) Isabel J.F. Hofman et al.   HAEMATOLOGICA

Herbal Medicine AC591 Prevents Oxaliplatin-Induced Peripheral Neuropathy in Animal Model and Cancer Patients

(2017) Xiaolan Cheng et al.   Frontiers in Pharmacology

Phytochemical-induced nucleolar stress results in the inhibition of breast cancer cell proliferation

(2017) Anna Lewinska et al.   Redox Biology

The Transcriptional Landscape of p53 Signalling Pathway

(2017) Chizu Tanikawa et al.   EBioMedicine

Expression of ribosomal proteins in normal and cancerous human prostate tissue

(2017) Callum Arthurs et al.   PLoS One

Ribosomal protein L23 negatively regulates cellular apoptosis via the RPL23/Miz-1/c-Myc circuit in higher-risk myelodysplastic syndrome

(2017) Yuekun Qi et al.   Scientific Reports

TBMS1 exerts its cytotoxicity in NCI-H460 lung cancer cells through nucleolar stress-induced p53/MDM2-dependent mechanism, a quantitative proteomics study

(2016) Yingying Lin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Nucleophosmin: from structure and function to disease development

(2016) Joseph K. Box et al.   BMC MOLECULAR BIOLOGY

Reduced phosphorylation of ribosomal protein S6 is associated with sensitivity to MEK inhibition in gastric cancer cells

(2016) Yuka Hirashita et al.   CANCER SCIENCE

GRWD1 negatively regulates p53 via the RPL11–MDM2 pathway and promotes tumorigenesis

(2016) Kota Kayama et al.   EMBO REPORTS

Over-expressed RPL34 promotes malignant proliferation of non-small cell lung cancer cells

(2016) Shaoxing Yang et al.   GENE

Nucleolus-derived mediators in oncogenic stress response and activation of p53-dependent pathways

(2016) Dariusz Stępiński   HISTOCHEMISTRY AND CELL BIOLOGY

Acquisition of Chemoresistance and Other Malignancy-related Features of Colorectal Cancer Cells Are Incremented by Ribosome-inactivating Stress

(2016) Chang-Kyu Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of nucleophosmin expression inhibited proliferation and induced apoptosis in salivary gland adenoid cystic carcinoma

(2016) Shihao Li et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Induction of the 5S RNP–Mdm2–p53 ribosomal stress pathway delays the initiation but fails to eradicate established murine acute myeloid leukemia

(2016) P Jaako et al.   LEUKEMIA

mTORC1 and -2 Coordinate Transcriptional and Translational Reprogramming in Resistance to DNA Damage and Replicative Stress in Breast Cancer Cells

(2016) Deborah Silvera et al.   MOLECULAR AND CELLULAR BIOLOGY

Disruption of the RP-MDM2-p53 pathway accelerates APC loss-induced colorectal tumorigenesis

(2016) S Liu et al.   ONCOGENE

Dietary restriction: could it be considered as speed bump on tumor progression road?

(2016) Antonina Cangemi et al.   TUMOR BIOLOGY

Increased nucleophosmin expression is a strong predictor of recurrence and prognosis in patients with N0M0 upper tract urothelial carcinoma undergoing radical nephroureterectomy

(2016) Harutake Sawazaki et al.   WORLD JOURNAL OF UROLOGY

Involvement of human ribosomal proteins in nucleolar structure and p53-dependent nucleolar stress

(2016) Emilien Nicolas et al.   Nature Communications

A redox mechanism underlying nucleolar stress sensing by nucleophosmin

(2016) Kai Yang et al.   Nature Communications

The human box C/D snoRNAs U3 and U8 are required for pre-rRNA processing and tumorigenesis

(2016) Jean-Louis Langhendries et al.   Oncotarget

GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF

(2016) Sun Lee et al.   Oncotarget

5-FU targets rpL3 to induce mitochondrial apoptosis via cystathionine-β-synthase in colon cancer cells lacking p53

(2016) Valentina Pagliara et al.   Oncotarget

Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer

(2016) Eya Wolfson et al.   Oncotarget

Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling

(2016) Jaclyn Quin et al.   Oncotarget

Farnesiferol c induces apoptosis via regulation of L11 and c-Myc with combinational potential with anticancer drugs in non-small-cell lung cancers

(2016) Ji Hoon Jung et al.   Scientific Reports

Human Ribosomal RNA-Derived Resident MicroRNAs as the Transmitter of Information upon the Cytoplasmic Cancer Stress

(2016) Masaru Yoshikawa et al.   Biomed Research International

The nucleolar protein NIFK promotes cancer progression via CK1α/β-catenin in metastasis and Ki-67-dependent cell proliferation

(2016) Tsung-Chieh Lin et al.   eLife

Development of Soft Tissue Sarcomas in Ribosomal Proteins L5 and S24 Heterozygous Mice

(2016) Shideh Kazerounian et al.   Journal of Cancer

Profiling of Small Nucleolar RNAs by Next Generation Sequencing: Potential New Players for Breast Cancer Prognosis

(2016) Preethi Krishnan et al.   PLoS One

Highly expressed ribosomal protein L34 indicates poor prognosis in osteosarcoma and its knockdown suppresses osteosarcoma proliferation probably through translational control

(2016) Shuju Luo et al.   Scientific Reports

rpL3 promotes the apoptosis of p53 mutated lung cancer cells by down-regulating CBS and NFκB upon 5-FU treatment

(2016) Annapina Russo et al.   Scientific Reports

Knockdown of c-Myc inhibits cell proliferation by negatively regulating the Cdk/Rb/E2F pathway in nasopharyngeal carcinoma cells

(2015) Z. Niu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The nucleolus as a fundamental regulator of the p53 response and a new target for cancer therapy

(2015) Simone J. Woods et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The roles of nucleolin subcellular localization in cancer

(2015) Caroline Madeleine Berger et al.   BIOCHIMIE

Small nucleolar RNA U91 is a new internal control for accurate microRNAs quantification in pancreatic cancer

(2015) Alexey Popov et al.   BMC CANCER

Regulatory role of rpL3 in cell response to nucleolar stress induced by Act D in tumor cells lacking functional p53

(2015) Annapina Russo et al.   CELL CYCLE

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

(2015) Masahiro Morita et al.   CELL CYCLE

Hrr25/CK1δ-directed release of Ltv1 from pre-40S ribosomes is necessary for ribosome assembly and cell growth

(2015) Homa Ghalei et al.   JOURNAL OF CELL BIOLOGY

Low-Dose Actinomycin-D Induces Redistribution of Wild-Type and Mutated Nucleophosmin Followed by Cell Death in Leukemic Cells

(2015) Barbora Brodská et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Small nucleolar RNA 78 promotes the tumorigenesis in non-small cell lung cancer

(2015) Di Zheng et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Integrated analysis of the prostate cancer small-nucleolar transcriptome reveals SNORA55 as a driver of prostate cancer progression

(2015) Francesco Crea et al.   Molecular Oncology

The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer

(2015) Zurab Siprashvili et al.   NATURE GENETICS

Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate

(2015) F Scala et al.   ONCOGENE

RNAi-mediated RPL34 knockdown suppresses the growth of human gastric cancer cells

(2015) HUI LIU et al.   ONCOLOGY REPORTS

The RNA recognition motif of NIFK is required for rRNA maturation during cell cycle progression

(2015) Wen-An Pan et al.   RNA Biology

RRP12 is a crucial nucleolar protein that regulates p53 activity in osteosarcoma cells

(2015) Young Joon Choi et al.   TUMOR BIOLOGY

p53-guided response to nucleostemin loss in normal versus cancer cells

(2015) R Y L Tsai   Cell Death & Disease

Combination Therapy Targeting Ribosome Biogenesis and mRNA Translation Synergistically Extends Survival in MYC-Driven Lymphoma

(2015) J. R. Devlin et al.   Cancer Discovery

Mutual Regulation of FOXM1, NPM and ARF Proteins

(2015) Bulbul Pandit et al.   Journal of Cancer

The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies

(2015) Patrick Ehm et al.   Nucleus

Protecting the normal in order to better kill the cancer

(2015) Bingya Liu et al.   Cancer Medicine

The tumor suppressor SHIP1 colocalizes in nucleolar cavities with p53 and components of PML nuclear bodies

(2015) Patrick Ehm et al.   Nucleus

Targeting the nucleolus for cancer intervention

(2014) Jaclyn E. Quin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Deregulated expression of Nucleophosmin 1 in gastric cancer and its clinicopathological implications

(2014) Mariana Ferreira Leal et al.   BMC GASTROENTEROLOGY

Letters to the Editor: Cardiomyocyte-secreted acetylcholine

(2014) Achilles Pappano   FASEB JOURNAL

Induced Expression of Nucleolin Phosphorylation-Deficient Mutant Confers Dominant-Negative Effect on Cell Proliferation

(2014) Shu Xiao et al.   PLoS One

Functional ultrastructure of the plant nucleolus

(2014) Dariusz Stępiński   PROTOPLASMA

Cardioprotective Effect of Clarithromycin on Doxorubicin-Induced Cardiac Toxicity in Rats.

(2014) Mustafa Dogan   UHOD-Uluslararasi Hematoloji-Onkoloji Dergisi

Nucleolar control of p53: a cellular Achilles’ heel and a target for cancer therapy

(2013) Nikolina Vlatković et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

AKT signalling is required for ribosomal RNA synthesis and progression of Eμ-MycB-cell lymphomain vivo

(2013) Jennifer R. Devlin et al.   FEBS Journal

Ribosomal Protein S14 Negatively Regulates c-Myc Activity

(2013) Xiang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Effects on ARF Stability by Normal versus Oncogenic Levels of c-Myc Expression

(2013) Delin Chen et al.   MOLECULAR CELL

Ribosomal proteins L5 and L11 co-operatively inactivate c-Myc via RNA-induced silencing complex

(2013) J-M Liao et al.   ONCOGENE

Akt activation enhances ribosomal RNA synthesis through casein kinase II and TIF-IA

(2013) L. X. T. Nguyen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of RNA Polymerase I as a Therapeutic Strategy to Promote Cancer-Specific Activation of p53

(2012) Megan J. Bywater et al.   CANCER CELL

Interactions of Nucleolin and Ribosomal Protein L26 (RPL26) in Translational Control of Human p53 mRNA

(2012) Jing Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

(2012) C. Lee et al.   Science Translational Medicine

Specific domains of nucleolin interact with Hdm2 and antagonize Hdm2-mediated p53 ubiquitination

(2011) Purvi Bhatt et al.   FEBS Journal

Signaling to the ribosome in cancer-It is more than just mTORC1

(2011) Katherine M. Hannan et al.   IUBMB LIFE

CK2 functionally interacts with AKT/PKB to promote the β-catenin-dependent expression of survivin and enhance cell survival

(2011) Daniela P. Ponce et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Ribosomal Protein L11 Recruits miR-24/miRISC To Repress c-Myc Expression in Response to Ribosomal Stress

(2011) K. B. Challagundla et al.   MOLECULAR AND CELLULAR BIOLOGY

AKT Promotes rRNA Synthesis and Cooperates with c-MYC to Stimulate Ribosome Biogenesis in Cancer

(2011) J. C. Chan et al.   Science Signaling

Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index

(2010) C. Lee et al.   CANCER RESEARCH

Specific activation of the p53 pathway by low dose actinomycin D: A new route to p53 based cyclotherapy

(2010) Meng Ling Choong et al.   CELL CYCLE

The ARF Tumor Suppressor Controls Ribosome Biogenesis by Regulating the RNA Polymerase I Transcription Factor TTF-I

(2010) Frédéric Lessard et al.   MOLECULAR CELL

1A6/DRIM, a Novel t-UTP, Activates RNA Polymerase I Transcription and Promotes Cell Proliferation

(2010) Qunhui Peng et al.   PLoS One

Toxicity and Efficacy of 5-Fluorouracil and Capecitabine in a Patient With TYMS Gene Polymorphism: A Challenge or a Dilemma?

(2009) Armin Shahrokni et al.   Clinical Colorectal Cancer

Growth control and ribosome biogenesis

(2009) Harri Lempiäinen et al.   CURRENT OPINION IN CELL BIOLOGY

Dysregulation of Ribosome Biogenesis and Translational Capacity Is Associated with Tumor Progression of Human Breast Cancer Cells

(2009) Stéphane Belin et al.   PLoS One

Immunodetection of nucleolar proteins and ultrastructure of nucleoli of soybean root meristematic cells treated with chilling stress and after recovery

(2009) Dariusz Stępiński   PROTOPLASMA

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7γ

(2008) Paola Bonetti et al.   JOURNAL OF CELL BIOLOGY

CSIG Inhibits PTEN Translation in Replicative Senescence

(2008) L. Ma et al.   MOLECULAR AND CELLULAR BIOLOGY

Identification of RPS14 as a 5q- syndrome gene by RNA interference screen

(2008) Benjamin L. Ebert et al.   NATURE

Nucleophosmin interacts directly with c-Myc and controls c-Myc-induced hyperproliferation and transformation

(2008) Z. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA