Pexophagy in yeast and mammals: an update on mysteries

Pex3 and Atg37 compete to regulate the interaction between the pexophagy receptor, Atg30, and the Hrr25 kinase

(2018) Katarzyna Zientara-Rytter et al.   Autophagy

Catalase inhibition induces pexophagy through ROS accumulation

(2018) Joon No Lee et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Dual role of USP30 in controlling basal pexophagy and mitophagy

(2018) Elena Marcassa et al.   EMBO REPORTS

A molecular perspective of mammalian autophagosome biogenesis

(2018) Thomas J. Mercer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Redox Regulation of Homeostasis and Proteostasis in Peroxisomes

(2018) Cheryl L. Walker et al.   PHYSIOLOGICAL REVIEWS

The Peroxisome-Mitochondria Connection: How and Why?

(2017) Marc Fransen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

VAPs and ACBD5 tether peroxisomes to the ER for peroxisome maintenance and lipid homeostasis

(2017) Rong Hua et al.   JOURNAL OF CELL BIOLOGY

ACBD5 and VAPB mediate membrane associations between peroxisomes and the ER

(2017) Joseph L. Costello et al.   JOURNAL OF CELL BIOLOGY

Mitochondrial fission facilitates the selective mitophagy of protein aggregates

(2017) Jonathon L. Burman et al.   JOURNAL OF CELL BIOLOGY

Newly born peroxisomes are a hybrid of mitochondrial and ER-derived pre-peroxisomes

(2017) Ayumu Sugiura et al.   NATURE

Peroxisomal Dysfunction in Age-Related Diseases

(2017) Cynthia M. Cipolla et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Proteomic Analysis of the Human Tankyrase Protein Interaction Network Reveals Its Role in Pexophagy

(2017) Xu Li et al.   Cell Reports

Pexophagy in yeasts

(2016) Masahide Oku et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of AAA + -proteins in peroxisome biogenesis and function

(2016) Immanuel Grimm et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Deficiency of a Retinal Dystrophy Protein, Acyl-CoA Binding Domain-containing 5 (ACBD5), Impairs Peroxisomal β-Oxidation of Very-long-chain Fatty Acids

(2016) Yuichi Yagita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PEX2 is the E3 ubiquitin ligase required for pexophagy during starvation

(2016) Graeme Sargent et al.   JOURNAL OF CELL BIOLOGY

TFEB at a glance

(2016) Gennaro Napolitano et al.   JOURNAL OF CELL SCIENCE

ACBD5 deficiency causes a defect in peroxisomal very long-chain fatty acid metabolism

(2016) Sacha Ferdinandusse et al.   JOURNAL OF MEDICAL GENETICS

Mechanisms of Selective Autophagy in Normal Physiology and Cancer

(2016) Joseph D. Mancias et al.   JOURNAL OF MOLECULAR BIOLOGY

Mechanistic insights into selective autophagy pathways: lessons from yeast

(2016) Jean-Claude Farré et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitin-Dependent And Independent Signals In Selective Autophagy

(2016) Aliaksandr Khaminets et al.   TRENDS IN CELL BIOLOGY

Mechanisms of Autophagy

(2015) Nobuo N. Noda et al.   Annual Review of Biophysics

EPAS1/HIF-2α is a driver of mammalian pexophagy

(2015) Miriam J Schönenberger et al.   Autophagy

Export-deficient monoubiquitinated PEX5 triggers peroxisome removal in SV40 large T antigen-transformed mouse embryonic fibroblasts

(2015) Marcus Nordgren et al.   Autophagy

Acute Ether Lipid Deficiency Affects Neutrophil Biology in Mice

(2015) Irfan J. Lodhi et al.   Cell Metabolism

Ether Lipid Deficiency Does Not Cause Neutropenia or Leukopenia in Mice and Men

(2015) Fabian Dorninger et al.   Cell Metabolism

Peroxisomal Lipid Synthesis Regulates Inflammation by Sustaining Neutrophil Membrane Phospholipid Composition and Viability

(2015) Irfan J. Lodhi et al.   Cell Metabolism

Peroxisomal Pex3 Activates Selective Autophagy of Peroxisomes via Interaction with the Pexophagy Receptor Atg30

(2015) Sarah F. Burnett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of endoplasmic reticulum turnover by selective autophagy

(2015) Aliaksandr Khaminets et al.   NATURE

ATM functions at the peroxisome to induce pexophagy in response to ROS

(2015) Jiangwei Zhang et al.   NATURE CELL BIOLOGY

USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria

(2015) Christian N. Cunningham et al.   NATURE CELL BIOLOGY

Pex14 is the sole component of the peroxisomal translocon that is required for pexophagy

(2014) Tim van Zutphen et al.   Autophagy

Atg37 regulates the assembly of the pexophagic receptor protein complex

(2014) Taras Y Nazarko   Autophagy

Deficiency of the exportomer components Pex1, Pex6, and Pex15 causes enhanced pexophagy inSaccharomyces cerevisiae

(2014) James M Nuttall et al.   Autophagy

The membrane peroxin PEX3 induces peroxisome-ubiquitination-linked pexophagy

(2014) Shun-ichi Yamashita et al.   Autophagy

The progression of peroxisomal degradation through autophagy requires peroxisomal division

(2014) Kai Mao et al.   Autophagy

Hif-2α Promotes Degradation of Mammalian Peroxisomes by Selective Autophagy

(2014) Katharina M. Walter et al.   Cell Metabolism

Peroxin Pex14p is the key component for coordinated autophagic degradation of mammalian peroxisomes by direct binding to LC3-II

(2014) Li Jiang et al.   GENES TO CELLS

Peroxisomal Atg37 binds Atg30 or palmitoyl-CoA to regulate phagophore formation during pexophagy

(2014) Taras Y. Nazarko et al.   JOURNAL OF CELL BIOLOGY

Hrr25 triggers selective autophagy–related pathways by phosphorylating receptor proteins

(2014) Chikara Tanaka et al.   JOURNAL OF CELL BIOLOGY

The Pex1-G844D mouse: A model for mild human Zellweger spectrum disorder

(2014) Shandi Hiebler et al.   MOLECULAR GENETICS AND METABOLISM

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

(2014) Baris Bingol et al.   NATURE

Diverse intracellular pathogens activate type III interferon expression from peroxisomes

(2014) Charlotte Odendall et al.   NATURE IMMUNOLOGY

Dynamic regulation of macroautophagy by distinctive ubiquitin-like proteins

(2014) Daniel J Klionsky et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Lumenal peroxisomal protein aggregates are removed by concerted fission and autophagy events

(2013) Selvambigai Manivannan et al.   Autophagy

Pexophagy-linked degradation of the peroxisomal membrane protein Pex3p involves the ubiquitin–proteasome system

(2013) Chris Williams et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Substrate recognition in selective autophagy and the ubiquitin–proteasome system

(2013) Anne Schreiber et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Peroxisomal metabolism and oxidative stress

(2013) Marcus Nordgren et al.   BIOCHIMIE

Cholesterol biosynthesis and ER stress in peroxisome deficiency

(2013) Phyllis L. Faust et al.   BIOCHIMIE

The Scaffold Protein Atg11 Recruits Fission Machinery to Drive Selective Mitochondria Degradation by Autophagy

(2013) Kai Mao et al.   DEVELOPMENTAL CELL

Phosphorylation of mitophagy and pexophagy receptors coordinates their interaction with Atg8 and Atg11

(2013) Jean-Claude Farré et al.   EMBO REPORTS

Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane

(2013) R. Goold et al.   JOURNAL OF CELL SCIENCE

A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS

(2013) Jiangwei Zhang et al.   NATURE CELL BIOLOGY

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

(2013) Charleen T. Chu et al.   NATURE CELL BIOLOGY

Atg36

(2012) Alison M. Motley et al.   Autophagy

Fission and proliferation of peroxisomes

(2012) M. Schrader et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondrial morphology in mitophagy and macroautophagy

(2012) Ligia C. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

Pex3-anchored Atg36 tags peroxisomes for degradation inSaccharomyces cerevisiae

(2012) Alison M Motley et al.   EMBO JOURNAL

The RING-type ubiquitin ligases Pex2p, Pex10p and Pex12p form a heteromeric complex that displays enhanced activity in an ubiquitin conjugating enzyme-selective manner

(2012) Fouzi El Magraoui et al.   FEBS Journal

The peroxisome: an update on mysteries

(2012) Markus Islinger et al.   HISTOCHEMISTRY AND CELL BIOLOGY

NBR1 acts as an autophagy receptor for peroxisomes

(2012) E. Deosaran et al.   JOURNAL OF CELL SCIENCE

The Role of Atg Proteins in Autophagosome Formation

(2011) Noboru Mizushima et al.   Annual Review of Cell and Developmental Biology

Selective autophagy mediated by autophagic adapter proteins

(2011) Terje Johansen et al.   Autophagy

Damaged peroxisomes are subject to rapid autophagic degradation in the yeastHansenula polymorpha

(2011) Tim van Zutphen et al.   Autophagy

Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease

(2011) Marc Fransen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The Three Musketeers of Autophagy: phosphorylation, ubiquitylation and acetylation

(2011) David G. McEwan et al.   TRENDS IN CELL BIOLOGY

Peroxisomes Are Signaling Platforms for Antiviral Innate Immunity

(2010) Evelyn Dixit et al.   CELL

Vps35 Mediates Vesicle Transport between the Mitochondria and Peroxisomes

(2010) Emélie Braschi et al.   CURRENT BIOLOGY

Biochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism

(2010) Paul P. Van Veldhoven   JOURNAL OF LIPID RESEARCH

Termination of autophagy and reformation of lysosomes regulated by mTOR

(2010) Li Yu et al.   NATURE

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The plasma lipidomic signature of nonalcoholic steatohepatitis

(2009) Puneet Puri et al.   HEPATOLOGY

Degradation of excess peroxisomes in mammalian liver cells by autophagy and other mechanisms

(2009) Sadaki Yokota et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Pex2 and Pex12 Function as Protein-Ubiquitin Ligases in Peroxisomal Protein Import

(2009) H. W. Platta et al.   MOLECULAR AND CELLULAR BIOLOGY

A Role for Ubiquitin in Selective Autophagy

(2009) Vladimir Kirkin et al.   MOLECULAR CELL

Peroxisome Dynamics in Cultured Mammalian Cells

(2009) Sofie J. Huybrechts et al.   TRAFFIC

Cargo-Selected Transport from the Mitochondria to Peroxisomes Is Mediated by Vesicular Carriers

(2008) Margaret Neuspiel et al.   CURRENT BIOLOGY

PpAtg30 Tags Peroxisomes for Turnover by Selective Autophagy

(2008) Jean-Claude Farré et al.   DEVELOPMENTAL CELL

The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes

(2008) Sayuri Hara-Kuge et al.   EXPERIMENTAL CELL RESEARCH

The peroxisome: still a mysterious organelle

(2008) Michael Schrader et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Ubiquitin signals autophagic degradation of cytosolic proteins and peroxisomes

(2008) P. K. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA