The Poisson distribution and beyond: methods for microfluidic droplet production and single cell encapsulation

“V-junction”: a novel structure for high-speed generation of bespoke droplet flows

(2015) Yun Ding et al.   ANALYST

Microchannel Anechoic Corner for Size-Selective Separation and Medium Exchange via Traveling Surface Acoustic Waves

(2015) Ghulam Destgeer et al.   ANALYTICAL CHEMISTRY

Emerging Technologies for Point-of-Care Management of HIV Infection

(2015) Hadi Shafiee et al.   Annual Review of Medicine

Developing robust, hydrogel-based, nanofiber-enabled encapsulation devices (NEEDs) for cell therapies

(2015) Duo An et al.   BIOMATERIALS

Enhanced single-cell printing by acoustophoretic cell focusing

(2015) I. Leibacher et al.   Biomicrofluidics

Single-cell printing based on impedance detection

(2015) J. Schoendube et al.   Biomicrofluidics

On demand nanoliter-scale microfluidic droplet generation, injection, and mixing using a passive microfluidic device

(2015) Uwe Tangen et al.   Biomicrofluidics

Jetting microfluidics with size-sorting capability for single-cell protease detection

(2015) Tengyang Jing et al.   BIOSENSORS & BIOELECTRONICS

Droplet generation via a single bubble transformation in a nanofluidic channel

(2015) S. Xiong et al.   LAB ON A CHIP

A versatile technology for droplet-based microfluidics: thermomechanical actuation

(2015) Vincent Miralles et al.   LAB ON A CHIP

Rapid and continuous magnetic separation in droplet microfluidic devices

(2015) Eric Brouzes et al.   LAB ON A CHIP

3D Printed Programmable Release Capsules

(2015) Maneesh K. Gupta et al.   NANO LETTERS

Multiscale assembly for tissue engineering and regenerative medicine

(2015) Sinan Guven et al.   TRENDS IN BIOTECHNOLOGY

Discordance of DNA Methylation Variance Between two Accessible Human Tissues

(2015) Ruiwei Jiang et al.   Scientific Reports

CotA laccase: high-throughput manipulation and analysis of recombinant enzyme libraries expressed in E. coli using droplet-based microfluidics

(2014) Thomas Beneyton et al.   ANALYST

One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution

(2014) Anastasia Zinchenko et al.   ANALYTICAL CHEMISTRY

A novel approach for encapsulating cells into monodisperse picolitre droplets actuated by microfluidic pulse inertia force

(2014) Hongcheng Wang et al.   Analytical Methods

Inertial Focusing in Microfluidics

(2014) Joseph M. Martel et al.   Annual Review of Biomedical Engineering

The particle valve: On-demand particle trapping, filtering, and release from a microfabricated polydimethylsiloxane membrane using surface acoustic waves

(2014) David J. Collins et al.   APPLIED PHYSICS LETTERS

Acoustic modulation of droplet size in a T-junction

(2014) Lothar Schmid et al.   APPLIED PHYSICS LETTERS

Cell encapsulation via microtechnologies

(2014) AhRan Kang et al.   BIOMATERIALS

A high-throughput cellulase screening system based on droplet microfluidics

(2014) Raluca Ostafe et al.   Biomicrofluidics

Facile Droplet-based Microfluidic Synthesis of Monodisperse IV–VI Semiconductor Nanocrystals with Coupled In-Line NIR Fluorescence Detection

(2014) Ioannis Lignos et al.   CHEMISTRY OF MATERIALS

A novel approach for drop-on-demand and particle encapsulation based on liquid bridge breakup

(2014) Dustin Moon et al.   EXPERIMENTAL THERMAL AND FLUID SCIENCE

Continuous Suspension of Lipids in Oil by the Selective Removal of Chloroform via Microfluidic Membrane Separation

(2014) Simon Berger et al.   INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH

Electrokinetic particle separation in a single-spiral microchannel

(2014) John DuBose et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Microfluidic on-demand droplet merging using surface acoustic waves

(2014) Muhsincan Sesen et al.   LAB ON A CHIP

Research highlights: microfluidic single-cell analysis from nucleic acids to proteins to functions

(2014) Rajan P. Kulkarni et al.   LAB ON A CHIP

Droplet optofluidic imaging for λ-bacteriophage detection via co-culture with host cell Escherichia coli

(2014) J. Q. Yu et al.   LAB ON A CHIP

Submicron separation of microspheres via travelling surface acoustic waves

(2014) Ghulam Destgeer et al.   LAB ON A CHIP

Particle separation using virtual deterministic lateral displacement (vDLD)

(2014) David J. Collins et al.   LAB ON A CHIP

Sorting drops and cells with acoustics: acoustic microfluidic fluorescence-activated cell sorter

(2014) Lothar Schmid et al.   LAB ON A CHIP

Microfluidic flow-focusing in ac electric fields

(2014) Say Hwa Tan et al.   LAB ON A CHIP

Deterministic lateral displacement for particle separation: a review

(2014) J. McGrath et al.   LAB ON A CHIP

Inertial microfluidic physics

(2014) Hamed Amini et al.   LAB ON A CHIP

Oxygen sensor nanoparticles for monitoring bacterial growth and characterization of dose–response functions in microfluidic screenings

(2014) Jialan Cao et al.   MICROCHIMICA ACTA

Separation of magnetic microparticles in segmented flow using asymmetric splitting regimes

(2014) Bert Verbruggen et al.   Microfluidics and Nanofluidics

Microfluidic organs-on-chips

(2014) Sangeeta N Bhatia et al.   NATURE BIOTECHNOLOGY

3D bioprinting of tissues and organs

(2014) Sean V Murphy et al.   NATURE BIOTECHNOLOGY

Stationary nanoliter droplet array with a substrate of choice for single adherent/nonadherent cell incubation and analysis

(2014) J. Shemesh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Interfacing picoliter droplet microfluidics with addressable microliter compartments using fluorescence activated cell sorting

(2014) Yunpeng Bai et al.   SENSORS AND ACTUATORS B-CHEMICAL

3D printing facilitated scaffold-free tissue unit fabrication

(2014) Yu Tan et al.   Biofabrication

One drop at a time: toward droplet microfluidics as a versatile tool for single-cell analysis

(2014) Agata Rakszewska et al.   NPG Asia Materials

Centrifuge-based cell encapsulation in hydrogel microbeads using sub-microliter sample solution

(2014) Hiroaki Onoe et al.   RSC Advances

Integrated pneumatic micro-pumps for high-throughput droplet-based microfluidics

(2014) Jae-Won Choi et al.   RSC Advances

Ultrarapid Generation of Femtoliter Microfluidic Droplets for Single-Molecule-Counting Immunoassays

(2013) Jung-uk Shim et al.   ACS Nano

Preparation of cell-encapsulation devices in confined microenvironment

(2013) Stefania Mazzitelli et al.   ADVANCED DRUG DELIVERY REVIEWS

Multiphase flow microfluidics for the production of single or multiple emulsions for drug delivery

(2013) Chun-Xia Zhao   ADVANCED DRUG DELIVERY REVIEWS

Label-free, high-throughput, electrical detection of cells in droplets

(2013) Evelien W. M. Kemna et al.   ANALYST

Microfluidic passive permeability assay using nanoliter droplet interface lipid bilayers

(2013) Takasi Nisisako et al.   ANALYST

Analytical detection techniques for droplet microfluidics—A review

(2013) Ying Zhu et al.   ANALYTICA CHIMICA ACTA

Droplet-Based Microfluidic Platform for High-Throughput, Multi-Parameter Screening of Photosensitizer Activity

(2013) Soongwon Cho et al.   ANALYTICAL CHEMISTRY

Cell-Based Drug Combination Screening with a Microfluidic Droplet Array System

(2013) Guan-Sheng Du et al.   ANALYTICAL CHEMISTRY

Sensitive, High Throughput Detection of Proteins in Individual, Surfactant-Stabilized Picoliter Droplets Using Nanoelectrospray Ionization Mass Spectrometry

(2013) Clive A. Smith et al.   ANALYTICAL CHEMISTRY

Interfacing Droplet Microfluidics with Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry: Label-Free Content Analysis of Single Droplets

(2013) Simon K. Küster et al.   ANALYTICAL CHEMISTRY

The Potential Impact of Droplet Microfluidics in Biology

(2013) Thomas Schneider et al.   ANALYTICAL CHEMISTRY

An On-Chip, Multichannel Droplet Sorter Using Standing Surface Acoustic Waves

(2013) Sixing Li et al.   ANALYTICAL CHEMISTRY

Separation of Escherichia coli Bacteria from Peripheral Blood Mononuclear Cells Using Standing Surface Acoustic Waves

(2013) Ye Ai et al.   ANALYTICAL CHEMISTRY

Microfluidic Synthesis of Cell-Type-Specific Artificial Extracellular Matrix Hydrogels

(2013) Simone Allazetta et al.   BIOMACROMOLECULES

Encapsulation of single cells on a microfluidic device integrating droplet generation with fluorescence-activated droplet sorting

(2013) Liang Wu et al.   BIOMEDICAL MICRODEVICES

A high-throughput screen for antibiotic drug discovery

(2013) Thomas C. Scanlon et al.   BIOTECHNOLOGY AND BIOENGINEERING

High-throughput deterministic single-cell encapsulation and droplet pairing, fusion, and shrinkage in a single microfluidic device

(2013) Rogier M. Schoeman et al.   ELECTROPHORESIS

Sample introduction of single selenized yeast cells (Saccharomyces cerevisiae) by micro droplet generation into an ICP-sector field mass spectrometer for label-free detection of trace elements

(2013) Kaori Shigeta et al.   JOURNAL OF ANALYTICAL ATOMIC SPECTROMETRY

Controlling one protein crystal growth by droplet-based microfluidic system

(2013) Hiroshi Yamaguchi et al.   JOURNAL OF BIOCHEMISTRY

From tubes to drops: droplet-based microfluidics for ultrahigh-throughput biology

(2013) T M Tran et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

A review of the theory, methods and recent applications of high-throughput single-cell droplet microfluidics

(2013) Todd P Lagus et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

High-purity and label-free isolation of circulating tumor cells (CTCs) in a microfluidic platform by using optically-induced-dielectrophoretic (ODEP) force

(2013) Song-Bin Huang et al.   LAB ON A CHIP

SAW-controlled drop size for flow focusing

(2013) Lothar Schmid et al.   LAB ON A CHIP

On-chip magnetic separation and encapsulation of cells in droplets

(2013) Aaron Chen et al.   LAB ON A CHIP

Surface acoustic waves for on-demand production of picoliter droplets and particle encapsulation

(2013) David J. Collins et al.   LAB ON A CHIP

Real-time image processing for label-free enrichment of Actinobacteria cultivated in picolitre droplets

(2013) Emerson Zang et al.   LAB ON A CHIP

One-step microfluidic generation of pre-hatching embryo-like core–shell microcapsules for miniaturized 3D culture of pluripotent stem cells

(2013) Pranay Agarwal et al.   LAB ON A CHIP

High-throughput screening for industrial enzyme production hosts by droplet microfluidics

(2013) Staffan L. Sjostrom et al.   LAB ON A CHIP

Experimental demonstration of optical transport, sorting and self-arrangement using a ‘tractor beam’

(2013) O. Brzobohatý et al.   Nature Photonics

Single-cell analysis and sorting using droplet-based microfluidics

(2013) Linas Mazutis et al.   Nature Protocols

A Microfluidic Device for Preparing Next Generation DNA Sequencing Libraries and for Automating Other Laboratory Protocols That Require One or More Column Chromatography Steps

(2013) Swee Jin Tan et al.   PLoS One

A Microfluidic Device to Sort Cells Based on Dynamic Response to a Stimulus

(2013) Swee Jin Tan et al.   PLoS One

High-throughput co-encapsulation of self-ordered cell trains: cell pair interactions in microdroplets

(2013) Todd P. Lagus et al.   RSC Advances

Encapsulated Islet Transplantation: Strategies and Clinical Trials

(2013) Brian Buder et al.   Immune Network

High-Throughput Analysis of Protein–Protein Interactions in Picoliter-Volume Droplets Using Fluorescence Polarization

(2012) Jae-Won Choi et al.   ANALYTICAL CHEMISTRY

Droplet Microfluidics-A Tool for Single-Cell Analysis

(2012) Haakan N. Joensson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Building droplet-based microfluidic systems for biological analysis

(2012) Xize Niu et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Neural stem cells encapsulated in a functionalized self-assembling peptide hydrogel for brain tissue engineering

(2012) Tzu-Yun Cheng et al.   BIOMATERIALS

Microfluidic carbon-blackened polydimethylsiloxane device with reduced ultra violet background fluorescence for simultaneous two-color ultra violet/visible-laser induced fluorescence detection in single cell analysis

(2012) Lukas Galla et al.   Biomicrofluidics

Density-dependent separation of encapsulated cells in a microfluidic channel by using a standing surface acoustic wave

(2012) Jeonghun Nam et al.   Biomicrofluidics

Picoliter Cell Lysate Assays in Microfluidic Droplet Compartments for Directed Enzyme Evolution

(2012) Balint Kintses et al.   CHEMISTRY & BIOLOGY

Continuous and Segmented Flow Microfluidics: Applications in High-throughput Chemistry and Biology

(2012) Claire E. Stanley et al.   CHIMIA

Microfluidic single cell analysis: from promise to practice

(2012) Véronique Lecault et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

High-yield cell ordering and deterministic cell-in-droplet encapsulation using Dean flow in a curved microchannel

(2012) Evelien W. M. Kemna et al.   LAB ON A CHIP

The application of an optically switched dielectrophoretic (ODEP) force for the manipulation and assembly of cell-encapsulating alginate microbeads in a microfluidic perfusion cell culture system for bottom-up tissue engineering

(2012) Yen-Heng Lin et al.   LAB ON A CHIP

Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets

(2012) Eujin Um et al.   LAB ON A CHIP

Microfluidic sorting of arbitrary cells with dynamic optical tweezers

(2012) Benjamin Landenberger et al.   LAB ON A CHIP

Novel technologies for the formation of 2-D and 3-D droplet interface bilayer networks

(2012) Yuval Elani et al.   LAB ON A CHIP

Pulsed laser triggered high speed microfluidic fluorescence activated cell sorter

(2012) Ting-Hsiang Wu et al.   LAB ON A CHIP

Selective droplet coalescence using microfluidic systems

(2012) Linas Mazutis et al.   LAB ON A CHIP

Droplet microfluidics for high-throughput biological assays

(2012) Mira T. Guo et al.   LAB ON A CHIP

A completely in vitro ultrahigh-throughput droplet-based microfluidic screening system for protein engineering and directed evolution

(2012) Ali Fallah-Araghi et al.   LAB ON A CHIP

Programmable active droplet generation enabled by integrated pneumatic micropumps

(2012) Yong Zeng et al.   LAB ON A CHIP

Revisiting lab-on-a-chip technology for drug discovery

(2012) Pavel Neužil et al.   NATURE REVIEWS DRUG DISCOVERY

Single step emulsification for the generation of multi-component double emulsions

(2012) L. L. A. Adams et al.   Soft Matter

Core-Shell Hydrogel Microcapsules for Improved Islets Encapsulation

(2012) Minglin Ma et al.   Advanced Healthcare Materials

Microfluidic-Based Synthesis of Hydrogel Particles for Cell Microencapsulation and Cell-Based Drug Delivery

(2012) Jiandi Wan   Polymers

Detection of Single Enzymatic Events in Rare or Single Cells Using Microfluidics

(2011) Sissel Juul et al.   ACS Nano

Teaching Single-Cell Digital Analysis Using Droplet-Based Microfluidics

(2011) Majdi Najah et al.   ANALYTICAL CHEMISTRY

Microfluidics for single cell analysis

(2011) Huabing Yin et al.   CURRENT OPINION IN BIOTECHNOLOGY

Fast on-demand droplet fusion using transient cavitation bubbles

(2011) Z. G. Li et al.   LAB ON A CHIP

High-speed droplet generation on demand driven by pulse laser-induced cavitation

(2011) Sung-Yong Park et al.   LAB ON A CHIP

Droplet size based separation by deterministic lateral displacement—separating droplets by cell-induced shrinking

(2011) Haakan N. Joensson et al.   LAB ON A CHIP

Inkjet-like printing of single-cells

(2011) Azmi Yusof et al.   LAB ON A CHIP

Microfluidic fabrication of microengineered hydrogels and their application in tissue engineering

(2011) Bong Geun Chung et al.   LAB ON A CHIP

Somatic and stem cell pairing and fusion using a microfluidic array device

(2011) Ya Qu et al.   Microfluidics and Nanofluidics

A microdroplet dilutor for high-throughput screening

(2011) Xize Niu et al.   Nature Chemistry

Droplet based microfluidics

(2011) Ralf Seemann et al.   REPORTS ON PROGRESS IN PHYSICS

Encapsulating Bacteria in Agarose Microparticles Using Microfluidics for High-Throughput Cell Analysis and Isolation

(2010) Ye-Jin Eun et al.   ACS Chemical Biology

Particle Focusing in Staged Inertial Microfluidic Devices for Flow Cytometry

(2010) John Oakey et al.   ANALYTICAL CHEMISTRY

Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology

(2010) Ashleigh B. Theberge et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Random breakup of microdroplets for single-cell encapsulation

(2010) Eujin Um et al.   APPLIED PHYSICS LETTERS

Bio-electrospraying and droplet-based microfluidics: control of cell numbers within living residues

(2010) Jongin Hong et al.   Biomedical Materials

Two-phase microfluidic flows

(2010) Chun-Xia Zhao et al.   CHEMICAL ENGINEERING SCIENCE

Microfluidic lab-on-a-chip platforms: requirements, characteristics and applications

(2010) Daniel Mark et al.   CHEMICAL SOCIETY REVIEWS

High-Efficiency Single-Molecule Detection within Trapped Aqueous Microdroplets

(2010) Monpichar Srisa-Art et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Smart Microgel Capsules from Macromolecular Precursors

(2010) Sebastian Seiffert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Passive self-synchronized two-droplet generation

(2010) Jongin Hong et al.   LAB ON A CHIP

A double droplet trap system for studying mass transport across a droplet-droplet interface

(2010) Yunpeng Bai et al.   LAB ON A CHIP

Hydrophilic PDMS microchannels for high-throughput formation of oil-in-water microdroplets and water-in-oil-in-water double emulsions

(2010) Wolfgang-Andreas C. Bauer et al.   LAB ON A CHIP

Overview of single-cell analyses: microdevices and applications

(2010) Sara Lindström et al.   LAB ON A CHIP

Surface acoustic wave actuated cell sorting (SAWACS)

(2010) T. Franke et al.   LAB ON A CHIP

Dynamics of microfluidic droplets

(2010) Charles N. Baroud et al.   LAB ON A CHIP

Dynamic self-assembly and control of microfluidic particle crystals

(2010) W. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ultrahigh-throughput screening in drop-based microfluidics for directed evolution

(2010) J. J. Agresti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single cell analysis: the new frontier in ‘omics’

(2010) Daojing Wang et al.   TRENDS IN BIOTECHNOLOGY

Identification of rare progenitor cells from human periosteal tissue using droplet microfluidics

(2009) Monpichar Srisa-Art et al.   ANALYST

Coupling Microdroplet Microreactors with Mass Spectrometry: Reading the Contents of Single Droplets Online

(2009) Luis M. Fidalgo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Valve-based flow focusing for drop formation

(2009) Adam R. Abate et al.   APPLIED PHYSICS LETTERS

Genome based cell population heterogeneity promotes tumorigenicity: The evolutionary mechanism of cancer

(2009) Christine J. Ye et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Oil droplet generation in PDMS microchannel using an amphiphilic continuous phase

(2009) Su-Kyoung Chae et al.   LAB ON A CHIP

Inertial microfluidics

(2009) Dino Di Carlo   LAB ON A CHIP

Beating Poisson encapsulation statistics using close-packed ordering

(2009) Adam R. Abate et al.   LAB ON A CHIP

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

(2009) Jean-Christophe Baret et al.   LAB ON A CHIP

Microfluidic control of cell pairing and fusion

(2009) Alison M Skelley et al.   NATURE METHODS

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Microfluidic Droplet-Based Liquid−Liquid Extraction

(2008) Pascaline Mary et al.   ANALYTICAL CHEMISTRY

High-Throughput Single Copy DNA Amplification and Cell Analysis in Engineered Nanoliter Droplets

(2008) Palani Kumaresan et al.   ANALYTICAL CHEMISTRY

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

(2008) Jenifer Clausell-Tormos et al.   CHEMISTRY & BIOLOGY

Transition from squeezing to dripping in a microfluidic T-shaped junction

(2008) M. DE MENECH et al.   JOURNAL OF FLUID MECHANICS

Alginate bead fabrication and encapsulation of living cells under centrifugally induced artificial gravity conditions

(2008) Stefan Haeberle et al.   JOURNAL OF MICROENCAPSULATION

Drop on demand in a microfluidic chip

(2008) Jie Xu et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Thermally controlled droplet formation in flow focusing geometry: formation regimes and effect of nanoparticle suspension

(2008) Say-Hwa Tan et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Continuous particle separation in spiral microchannels using dean flows and differential migration

(2008) Ali Asgar S. Bhagat et al.   LAB ON A CHIP

Drop-based microfluidic devices for encapsulation of single cells

(2008) Sarah Köster et al.   LAB ON A CHIP

Controlled encapsulation of single-cells into monodisperse picolitre drops

(2008) Jon F. Edd et al.   LAB ON A CHIP

Droplet microfluidics

(2008) Shia-Yen Teh et al.   LAB ON A CHIP

Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays

(2008) Ansgar Huebner et al.   LAB ON A CHIP

Emulsification in a microfluidic flow-focusing device: effect of the viscosities of the liquids

(2008) Zhihong Nie et al.   Microfluidics and Nanofluidics

Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells

(2008) M. Chabert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microfluidic Synthesis of Nanomaterials

(2008) Yujun Song et al.   Small

Cell culture arrays using magnetic force-based cell patterning for dynamic single cell analysis

(2007) Kosuke Ino et al.   LAB ON A CHIP