Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology

The Origin of the "One Cell-One Antibody" Rule

(2014) C. Viret et al.   JOURNAL OF IMMUNOLOGY

Generation of Monodisperse Inorganic-Organic Janus Microspheres in a Microfluidic Device

(2009) Naveen Prasad et al.   ADVANCED FUNCTIONAL MATERIALS

Microfluidic Assembly of Magnetic Hydrogel Particles with Uniformly Anisotropic Structure

(2009) Chia-Hung Chen et al.   ADVANCED MATERIALS

Surface-enhanced Raman scattering in nanoliter droplets: towards high-sensitivity detection of mercury (II) ions

(2009) Guoqing Wang et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Shear-Driven Redistribution of Surfactant Affects Enzyme Activity in Well-Mixed Femtoliter Droplets

(2009) Yu Liu et al.   ANALYTICAL CHEMISTRY

Measuring Rapid Enzymatic Kinetics by Electrochemical Method in Droplet-Based Microfluidic Devices with Pneumatic Valves

(2009) Zuoyan Han et al.   ANALYTICAL CHEMISTRY

Analysis of Samples Stored as Individual Plugs in a Capillary by Electrospray Ionization Mass Spectrometry

(2009) Jian Pei et al.   ANALYTICAL CHEMISTRY

Spray Performance of Microfluidic Glass Devices with Integrated Pulled Nanoelectrospray Emitters

(2009) Peter Hoffmann et al.   ANALYTICAL CHEMISTRY

Controlling the Retention of Small Molecules in Emulsion Microdroplets for Use in Cell-Based Assays

(2009) Fabienne Courtois et al.   ANALYTICAL CHEMISTRY

Electro-Coalescence of Digitally Controlled Droplets

(2009) Xize Niu et al.   ANALYTICAL CHEMISTRY

Droplet-Based Microfluidic Systems for High-Throughput Single DNA Molecule Isothermal Amplification and Analysis

(2009) Linas Mazutis et al.   ANALYTICAL CHEMISTRY

Electroporation of Cells in Microfluidic Droplets

(2009) Yihong Zhan et al.   ANALYTICAL CHEMISTRY

Droplets for Ultrasmall-Volume Analysis

(2009) Daniel T. Chiu et al.   ANALYTICAL CHEMISTRY

Dilution-Free Analysis from Picoliter Droplets by Nano-Electrospray Ionization Mass Spectrometry

(2009) Ryan T. Kelly et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Coupling Microdroplet Microreactors with Mass Spectrometry: Reading the Contents of Single Droplets Online

(2009) Luis M. Fidalgo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Towards an Integrated Chemical Circuit

(2009) Detlev Belder   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Compartmentalization of Chemically Separated Components into Droplets

(2009) J. Scott Edgar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Detection and Analysis of Low-Abundance Cell-Surface Biomarkers Using Enzymatic Amplification in Microfluidic Droplets

(2009) Haakan N. Joensson et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Plug-Based Microfluidics with Defined Surface Chemistry to Miniaturize and Control Aggregation of Amyloidogenic Peptides

(2009) Matthias Meier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multiplex Label-Free Detection of Biomolecules with an Imprinted Suspension Array

(2009) Yuan-Jin Zhao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

In Situ Assembly and Screening of Enzyme Inhibitors with Surface-Tension Microarrays

(2009) Laurent Mugherli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microfluidic Confinement of Single Cells of Bacteria in Small Volumes Initiates High-Density Behavior of Quorum Sensing and Growth and Reveals Its Variability

(2009) James Q. Boedicker et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Performance of nanoliter-sized droplet-based microfluidic PCR

(2009) Fang Wang et al.   BIOMEDICAL MICRODEVICES

Analysis of Protein-Protein Interactions by Using Droplet-Based Microfluidics

(2009) Monpichar Srisa-Art et al.   CHEMBIOCHEM

Suzuki–Miyaura coupling reactions in aqueous microdroplets with catalytically active fluorous interfaces

(2009) Ashleigh B. Theberge et al.   CHEMICAL COMMUNICATIONS

Fabrication of Monodisperse Toroidal Particles by Polymer Solidification in Microfluidics

(2009) Baoguo Wang et al.   CHEMPHYSCHEM

Manufacture of chitosan microbeads using centrifugally driven flow of gel-forming solutions through a polymeric micronozzle

(2009) Daniel Mark et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

A microfluidic approach to fabricate monodisperse hollow or porous poly(HEMA–MMA) microspheres using single emulsions as templates

(2009) Hao Zhang et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Thermally mediated control of liquid microdroplets at a bifurcation

(2009) Yit-Fatt Yap et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Laterally Mobile, Functionalized Self-Assembled Monolayers at the Fluorous−Aqueous Interface in a Plug-Based Microfluidic System: Characterization and Testing with Membrane Protein Crystallization

(2009) Jason E. Kreutz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Simultaneous Determination of Gene Expression and Enzymatic Activity in Individual Bacterial Cells in Microdroplet Compartments

(2009) Jung-uk Shim et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In situ formation, manipulation, and imaging of droplet-encapsulated fibrin networks

(2009) Heather M. Evans et al.   LAB ON A CHIP

Surface acoustic wave (SAW) directed droplet flow in microfluidics for PDMS devices

(2009) Thomas Franke et al.   LAB ON A CHIP

An integrated cell culture lab on a chip: modular microdevices for cultivation of mammalian cells and delivery into microfluidic microdroplets

(2009) Hansjörg Hufnagel et al.   LAB ON A CHIP

Nucleation and solidification in static arrays of monodisperse drops

(2009) Jon F. Edd et al.   LAB ON A CHIP

Simultaneous measurement of reactions in microdroplets filled by concentration gradients

(2009) Nicolae Damean et al.   LAB ON A CHIP

Formation of supramolecular hydrogel microspheres via microfluidics

(2009) Wanyu Chen et al.   LAB ON A CHIP

Beating Poisson encapsulation statistics using close-packed ordering

(2009) Adam R. Abate et al.   LAB ON A CHIP

On-chip electrocoalescence of microdroplets as a function of voltage, frequency and droplet size

(2009) Michele Zagnoni et al.   LAB ON A CHIP

Nonviral gene vector formation in monodispersed picolitre incubator for consistent gene delivery

(2009) Albert Tsung-Hsi Hsieh et al.   LAB ON A CHIP

On-chip manipulation of continuous picoliter-volume superparamagnetic droplets using a magnetic force

(2009) Kai Zhang et al.   LAB ON A CHIP

A fast and efficient microfluidic system for highly selective one-to-one droplet fusion

(2009) Linas Mazutis et al.   LAB ON A CHIP

Multi-step microfluidic droplet processing: kinetic analysis of an in vitro translated enzyme

(2009) Linas Mazutis et al.   LAB ON A CHIP

Fluorescence-activated droplet sorting (FADS): efficient microfluidic cell sorting based on enzymatic activity

(2009) Jean-Christophe Baret et al.   LAB ON A CHIP

Synthesizing Microcapsules with Controlled Geometrical and Mechanical Properties with Microfluidic Double Emulsion Technology

(2009) Yves Hennequin et al.   LANGMUIR

Determination of Dynamic Interfacial Tension and Its Effect on Droplet Formation in the T-Shaped Microdispersion Process

(2009) K. Wang et al.   LANGMUIR

Kinetic Aspects of Emulsion Stabilization by Surfactants: A Microfluidic Analysis

(2009) Jean-Christophe Baret et al.   LANGMUIR

Janus Particles Templated from Double Emulsion Droplets Generated Using Microfluidics

(2009) Chia-Hung Chen et al.   LANGMUIR

Dynamics of Coalescence of Plugs with a Hydrophilic Wetting Layer Induced by Flow in a Microfluidic Chemistrode

(2009) Ying Liu et al.   LANGMUIR

Microdroplet-based PCR enrichment for large-scale targeted sequencing

(2009) Ryan Tewhey et al.   NATURE BIOTECHNOLOGY

Novel method for high-throughput colony PCR screening in nanoliter-reactors

(2009) Marcel Walser et al.   NUCLEIC ACIDS RESEARCH

Electrically initiated upstream coalescence cascade of droplets in a microfluidic flow

(2009) Michele Zagnoni et al.   PHYSICAL REVIEW E

Suppression of instabilities in multiphase flow by geometric confinement

(2009) Katherine J. Humphry et al.   PHYSICAL REVIEW E

Breaking of an Emulsion under an ac Electric Field

(2009) Abdou R. Thiam et al.   PHYSICAL REVIEW LETTERS

Janus-like polymer particles prepared via internal phase separation from emulsified polymer/oil droplets

(2009) Yi Wang et al.   POLYMER

Droplet microfluidic technology for single-cell high-throughput screening

(2009) E. Brouzes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Preparation of Uniform Microspheres Using a Simple Fluidic Device and Their Crystallization into Close-Packed Lattices

(2009) Sung-Wook Choi et al.   Small

Preparation of Monodisperse Biodegradable Polymer Microparticles Using a Microfluidic Flow-Focusing Device for Controlled Drug Delivery

(2009) Qiaobing Xu et al.   Small

Heck reactions using segmented flow conditions

(2009) Batoul Ahmed-Omer et al.   TETRAHEDRON LETTERS

Microfluidic Synthesis of Reversibly Swelling Porous Polymeric Microcapsules with Controlled Morphology

(2008) Sinoj Abraham et al.   ADVANCED MATERIALS

Controllable Microfluidic Production of Microbubbles in Water-in-Oil Emulsions and the Formation of Porous Microparticles

(2008) Jiandi Wan et al.   ADVANCED MATERIALS

Encoded Porous Beads for Label-Free Multiplex Detection of Tumor Markers

(2008) Yuanjin Zhao et al.   ADVANCED MATERIALS

Double Emulsion-Templated Nanoparticle Colloidosomes with Selective Permeability

(2008) Daeyeon Lee et al.   ADVANCED MATERIALS

The Digital Revolution: A New Paradigm for Microfluidics

(2008) Mohamed Abdelgawad et al.   ADVANCED MATERIALS

Microfluidic Droplet-Based Liquid−Liquid Extraction

(2008) Pascaline Mary et al.   ANALYTICAL CHEMISTRY

Monitoring of Real-Time Streptavidin−Biotin Binding Kinetics Using Droplet Microfluidics

(2008) Monpichar Srisa-Art et al.   ANALYTICAL CHEMISTRY

Sizing Subcellular Organelles and Nanoparticles Confined within Aqueous Droplets

(2008) Jennifer C. Gadd et al.   ANALYTICAL CHEMISTRY

On-Chip Single-Copy Real-Time Reverse-Transcription PCR in Isolated Picoliter Droplets

(2008) N. Reginald Beer et al.   ANALYTICAL CHEMISTRY

Development of Quantitative Cell-Based Enzyme Assays in Microdroplets

(2008) Ansgar Huebner et al.   ANALYTICAL CHEMISTRY

Chemical Reaction Imaging within Microfluidic Devices Using Confocal Raman Spectroscopy:  The Case of Water and Deuterium Oxide as a Model System

(2008) Flavie Sarrazin et al.   ANALYTICAL CHEMISTRY

Sampling and Electrophoretic Analysis of Segmented Flow Streams Using Virtual Walls in a Microfluidic Device

(2008) Gregory T. Roman et al.   ANALYTICAL CHEMISTRY

High-Throughput Single Copy DNA Amplification and Cell Analysis in Engineered Nanoliter Droplets

(2008) Palani Kumaresan et al.   ANALYTICAL CHEMISTRY

Micro Total Analysis Systems: Latest Achievements

(2008) Jonathan West et al.   ANALYTICAL CHEMISTRY

High-Throughput Quantitative Polymerase Chain Reaction in Picoliter Droplets

(2008) Margaret Macris Kiss et al.   ANALYTICAL CHEMISTRY

Continuous-Flow Polymerase Chain Reaction of Single-Copy DNA in Microfluidic Microdroplets

(2008) Yolanda Schaerli et al.   ANALYTICAL CHEMISTRY

From Microdroplets to Microfluidics: Selective Emulsion Separation in Microfluidic Devices

(2008) Luis M. Fidalgo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Droplet-Based Microreactors for the Synthesis of Magnetic Iron Oxide Nanoparticles

(2008) Lucas Frenz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An Integrated Device for Monitoring Time-Dependent in vitro Expression From Single Genes in Picolitre Droplets

(2008) Fabienne Courtois et al.   CHEMBIOCHEM

Microfluidic-Assisted Synthesis of Polymer Particles

(2008) C. A. Serra et al.   CHEMICAL ENGINEERING & TECHNOLOGY

Droplet-Based Microfluidic Platforms for the Encapsulation and Screening of Mammalian Cells and Multicellular Organisms

(2008) Jenifer Clausell-Tormos et al.   CHEMISTRY & BIOLOGY

Thermally controlled droplet formation in flow focusing geometry: formation regimes and effect of nanoparticle suspension

(2008) Say-Hwa Tan et al.   JOURNAL OF PHYSICS D-APPLIED PHYSICS

Novel one-pot route to monodisperse thermosensitive hollow microcapsules in a microfluidic system

(2008) Chang-Hyung Choi et al.   LAB ON A CHIP

Droplet-based microfluidic system for individual Caenorhabditis elegans assay

(2008) Weiwei Shi et al.   LAB ON A CHIP

Effect of the gelation process on the production of alginate microbeads by microfluidic chip technology

(2008) Lorenzo Capretto et al.   LAB ON A CHIP

The electrochemical detection of droplets in microfluidic devices

(2008) Shujuan Liu et al.   LAB ON A CHIP

Drop-based microfluidic devices for encapsulation of single cells

(2008) Sarah Köster et al.   LAB ON A CHIP

Controlled encapsulation of single-cells into monodisperse picolitre drops

(2008) Jon F. Edd et al.   LAB ON A CHIP

Pillar-induced droplet merging in microfluidic circuits

(2008) Xize Niu et al.   LAB ON A CHIP

Biocompatible surfactants for water-in-fluorocarbon emulsions

(2008) C. Holtze et al.   LAB ON A CHIP

Detecting bacteria and determining their susceptibility to antibiotics by stochastic confinement in nanoliter droplets using plug-based microfluidics

(2008) James Q. Boedicker et al.   LAB ON A CHIP

Droplet microfluidics

(2008) Shia-Yen Teh et al.   LAB ON A CHIP

Microdroplets: A sea of applications?

(2008) Ansgar Huebner et al.   LAB ON A CHIP

Nanostructured biosensing platform—shadow edge lithography for high-throughput nanofabrication

(2008) John G. Bai et al.   LAB ON A CHIP

Monodisperse droplet generation and rapid trapping for single molecule detection and reaction kinetics measurement

(2008) Neil Reginald Beer et al.   LAB ON A CHIP

Observed velocity fluctuations in monodisperse droplet generators

(2008) Neil Reginald Beer et al.   LAB ON A CHIP

Reliable microfluidic on-chip incubation of droplets in delay-lines

(2008) Lucas Frenz et al.   LAB ON A CHIP

Microfluidic crystallization

(2008) Jacques Leng et al.   LAB ON A CHIP

Dropspots: a picoliter array in a microfluidic device

(2008) Christian H. J. Schmitz et al.   LAB ON A CHIP

Simple, robust storage of drops and fluids in a microfluidic device

(2008) Hakim Boukellal et al.   LAB ON A CHIP

A microfluidic droplet generator based on a piezoelectric actuator

(2008) Avishay Bransky et al.   LAB ON A CHIP

Static microdroplet arrays: a microfluidic device for droplet trapping, incubation and release for enzymatic and cell-based assays

(2008) Ansgar Huebner et al.   LAB ON A CHIP

Microfluidic Production of Droplet Pairs

(2008) Lucas Frenz et al.   LANGMUIR

Microchannel Emulsification: From Computational Fluid Dynamics to Predictive Analytical Model

(2008) Koen C. van Dijke et al.   LANGMUIR

Microfluidic Droplet Method for Nucleation Kinetics Measurements

(2008) Philippe Laval et al.   LANGMUIR

Designer emulsions using microfluidics

(2008) Rhutesh K. Shah et al.   Materials Today

Continuous generation of hydrogel beads and encapsulation of biological materials using a microfluidic droplet-merging channel

(2008) Eujin Um et al.   Microfluidics and Nanofluidics

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY

Continuous Flow Microwave-Assisted Reaction Optimization and Scale-Up Using Fluorous Spacer Technology

(2008) Otman Benali et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Fluorescence Lifetime Imaging of Mixing Dynamics in Continuous-Flow Microdroplet Reactors

(2008) Monpichar Srisa-Art et al.   PHYSICAL REVIEW LETTERS

Droplet Traffic in Microfluidic Networks: A Simple Model for Understanding and Designing

(2008) Michael Schindler et al.   PHYSICAL REVIEW LETTERS

Decompressing Emulsion Droplets Favors Coalescence

(2008) Nicolas Bremond et al.   PHYSICAL REVIEW LETTERS

Absolute Instability of a Liquid Jet in a Coflowing Stream

(2008) Andrew S. Utada et al.   PHYSICAL REVIEW LETTERS

Microfluidic high-throughput encapsulation and hydrodynamic self-sorting of single cells

(2008) M. Chabert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defined spatial structure stabilizes a synthetic multispecies bacterial community

(2008) H. J. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The chemistrode: A droplet-based microfluidic device for stimulation and recording with high temporal, spatial, and chemical resolution

(2008) D. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The development of microgels/nanogels for drug delivery applications

(2008) Jung Kwon Oh et al.   PROGRESS IN POLYMER SCIENCE

Fabrication of monodisperse thermosensitive microgels and gel capsules in microfluidic devices

(2008) Rhutesh K. Shah et al.   Soft Matter

The impact of next-generation sequencing technology on genetics

(2008) Elaine R. Mardis   TRENDS IN GENETICS

Controlled production of emulsions and particles by milli- and microfluidic techniques

(2007) W. Engl et al.   CURRENT OPINION IN COLLOID & INTERFACE SCIENCE

Alginate gelation in microfluidic channels

(2007) E. Amici et al.   FOOD HYDROCOLLOIDS

Drop Mixing in a Microchannel for Lab-on-a-Chip Platforms

(2007) Minsoung Rhee et al.   LANGMUIR

On-Chip Alginate Microencapsulation of Functional Cells

(2007) Victoria L. Workman et al.   MACROMOLECULAR RAPID COMMUNICATIONS