Interesting article on serendipity discovery of a Ankryin-B gene mutation in a remote population in the Skeena river in Northern Coastal British Columbia.
Interesting article on how hair color seems to change the appearance of the skin. In darker backgrounds, the skin appeared less wrinkled and more smooth as compared to lighter background.
TGF beta signaling in cancer is widely studied. It is tricky pathway and is called a double edged sword. In early stages in prevents cancer progression and in certain tumors it has a tumor promoting effect.
Lung cancer is an Elsevier journal with an impact factor of 5.705. It is a peer reviewed journal with main emphasis on all areas related to lung cancer.
This is the link to the journal: https://journals.sagepub.com/home/aut
The link in the description above is not working. It is a peer-reviewed academic journal with an impact factor of 4.609.
The tumor microenvironment encompasses the cancer stem cells and other molecules that help with tumor growth and progression. Studying it in detail provides insights on how to prevent and treat malignacies.
The authors discuss the importance of optimizing the cancer treatment doses to reduce physical and financial stress to patients. This study gives an example of abiraterone which was found to be more effective at a lower dose if consumed with a low-fat meal than on empty stomach.
Informative nature article on metastasis and how the tumor microenvironment is crucial to understanding how tumors thrive and the role of the immune system. This article discusses the two key models of metastasis- linear and parallel progression.
Biomarker assay development and validation is crucial for early drug development. This article provides good information on assay validation and the dangers of not conducting proper biomarker validation.
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