Harwinder Sidhu

United States Research

论文

评论了 Ankyrin-B Defects
Interesting article on serendipity discovery of a Ankryin-B gene mutation in a remote population in the Skeena river in Northern Coastal British Columbia.

论文

评论了 SDS-PAGE
Nicely written article with answers to commonly asked questions about SDS-PAGE technique.

基金

评论了 Bridge to Independence Award
Excellent opportunity for tenure track faculty or trainees with an MD or PhD degree to study autism and neuroscience.

论文

评论了 Hair color modulates skin appearance
Interesting article on how hair color seems to change the appearance of the skin. In darker backgrounds, the skin appeared less wrinkled and more smooth as compared to lighter background.

论文

评论了 TGF-beta Signaling in Cancer Treatment
TGF beta signaling in cancer is widely studied. It is tricky pathway and is called a double edged sword. In early stages in prevents cancer progression and in certain tumors it has a tumor promoting effect.

期刊

评论了 LUNG CANCER
Lung cancer is an Elsevier journal with an impact factor of 5.705. It is a peer reviewed journal with main emphasis on all areas related to lung cancer.

论文

评论了 Schizophrenia and schizophrenia spectrum disorders
Nicely written article on schizophrenia and associated disorders.

期刊

评论了 AUTISM
This is the link to the journal: https://journals.sagepub.com/home/aut The link in the description above is not working. It is a peer-reviewed academic journal with an impact factor of 4.609.

论文

评论了 How autism became autism
Interesting article on autism. Autism was first used to describe a schizophrenic condition but then changed to its present definition.

期刊

评论了 CANCER
Cancer is an internationally acclaimed interdisciplinary journal with an impact factor of 6.162. It is published semi-monthly by MDI.

论文

评论了 Tumor Microenvironment
The tumor microenvironment encompasses the cancer stem cells and other molecules that help with tumor growth and progression. Studying it in detail provides insights on how to prevent and treat malignacies.

论文

评论了 Minimalism in oncology
The authors discuss the importance of optimizing the cancer treatment doses to reduce physical and financial stress to patients. This study gives an example of abiraterone which was found to be more effective at a lower dose if consumed with a low-fat meal than on empty stomach.

论文

评论了 Understanding metastasis
Informative nature article on metastasis and how the tumor microenvironment is crucial to understanding how tumors thrive and the role of the immune system. This article discusses the two key models of metastasis- linear and parallel progression.

论文

评论了 Biomarker assay validation
Biomarker assay development and validation is crucial for early drug development. This article provides good information on assay validation and the dangers of not conducting proper biomarker validation.

论文

评论了 Epigenetics: Novel Therapeutics Targeting Epigenetics
Very interesting article on how enzymes modulating epigenetic gene expression are used to treat epigenetic disorders by switching the genes on or off.