标题
Recent derivatives from smaller classes of fermentation-derived antibacterials
作者
关键词
-
出版物
EXPERT OPINION ON THERAPEUTIC PATENTS
Volume 22, Issue 1, Pages 15-35
出版商
Informa Healthcare
发表日期
2011-12-04
DOI
10.1517/13543776.2012.642370
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Antimicrobial Properties of MX-2401, an Expanded-Spectrum Lipopeptide Active in the Presence of Lung Surfactant
- (2011) Dominique Dugourd et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Mechanism of Action and Limited Cross-Resistance of New Lipopeptide MX-2401
- (2011) E. Rubinchik et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Engineering antibiotic production and overcoming bacterial resistance
- (2011) Anne-Gaëlle Planson et al. Biotechnology Journal
- Novel classes of antibiotics or more of the same?
- (2011) Anthony RM Coates et al. BRITISH JOURNAL OF PHARMACOLOGY
- Novel Des-Fatty Acyl-Polymyxin B Derivatives with Pseudomonas aeruginosa-Specific Antimicrobial Activity
- (2011) Yuki Sato et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Critical shortage of new antibiotics in development against multidrug-resistant bacteria—Time to react is now
- (2011) Laura Freire-Moran et al. DRUG RESISTANCE UPDATES
- Antibiotics in the clinical pipeline in 2011
- (2011) Mark S Butler et al. JOURNAL OF ANTIBIOTICS
- Radical-mediated enzymatic carbon chain fragmentation-recombination
- (2011) Qi Zhang et al. Nature Chemical Biology
- Synthesis of Peptides Containing Overlapping Lanthionine Bridges on the Solid Phase: An Analogue of Rings D and E of the Lantibiotic Nisin
- (2011) Begum Mothia et al. ORGANIC LETTERS
- Fidaxomicin: A Macrocyclic Antibiotic for the Treatment ofClostridium difficileInfection
- (2011) Jennifer S Hardesty et al. PHARMACOTHERAPY
- Microbial metabolites: 45 years of wandering, wondering and discovering
- (2011) Satoshi Ōmura TETRAHEDRON
- Update in Tuberculosis 2009
- (2010) Charles L. Daley AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- A Novel Polymyxin Derivative That Lacks the Fatty Acid Tail and Carries Only Three Positive Charges Has Strong Synergism with Agents Excluded by the Intact Outer Membrane
- (2010) M. Vaara et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Genetically Engineered Lipopeptide Antibiotics Related to A54145 and Daptomycin with Improved Properties
- (2010) K. T. Nguyen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Polymyxins and their novel derivatives
- (2010) Martti Vaara CURRENT OPINION IN MICROBIOLOGY
- Daptomycin: pharmacology and clinical use
- (2010) Christos Kosmidis et al. EXPERT OPINION ON PHARMACOTHERAPY
- Antibiotics versus resistant bacteria: a continual challenge
- (2010) Herbert A Kirst EXPERT OPINION ON THERAPEUTIC PATENTS
- Production of novel lipopeptide antibiotics related to A54145 by Streptomyces fradiae mutants blocked in biosynthesis of modified amino acids and assignment of lptJ, lptK and lptL gene functions
- (2010) Dylan C Alexander et al. JOURNAL OF ANTIBIOTICS
- Structural characterization of a lipopeptide antibiotic A54145E(Asn3Asp9) produced by a genetically engineered strain of Streptomyces fradiae
- (2010) Jian-Qiao Gu et al. JOURNAL OF ANTIBIOTICS
- Antibiotic discovery in the twenty-first century: current trends and future perspectives
- (2010) Stefano Donadio et al. JOURNAL OF ANTIBIOTICS
- Fundamental functionality: recent developments in understanding the structure–activity relationships of lantibiotic peptides
- (2010) Avena C Ross et al. JOURNAL OF ANTIBIOTICS
- Novel polymyxin derivatives are effective in treating experimental Escherichia coli peritoneal infection in mice
- (2010) C. Vingsbo Lundberg et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Chemical modification of capuramycins to enhance antibacterial activity
- (2010) Elena Bogatcheva et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- In vitro antimicrobial activities of capuramycin analogues against non-tuberculous mycobacteria
- (2010) T. Dubuisson et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Daptomycin, a Bacterial Lipopeptide Synthesized by a Nonribosomal Machinery
- (2010) Lars Robbel et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Function-Oriented Synthesis of Simplified Caprazamycins: Discovery of Oxazolidine-Containing Uridine Derivatives as Antibacterial Agents against Drug-Resistant Bacteria
- (2010) Kensuke Ii et al. JOURNAL OF MEDICINAL CHEMISTRY
- Total Synthesis of (−)-Muraymycin D2 and Its Epimer
- (2010) Tetsuya Tanino et al. JOURNAL OF ORGANIC CHEMISTRY
- Origins and Evolution of Antibiotic Resistance
- (2010) J. Davies et al. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS
- Distamycins: Strategies for Possible Enhancement of Activity and Specificity
- (2010) Rita Cortesi et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Heterologous production of thiostrepton A and biosynthetic engineering of thiostrepton analogs
- (2010) Chaoxuan Li et al. Molecular BioSystems
- Identification of the genecluster involved in muraymycin biosynthesis from Streptomyces sp. NRRL 30471
- (2010) Lin Cheng et al. Molecular BioSystems
- An ATP-independent strategy for amide bond formation in antibiotic biosynthesis
- (2010) Masanori Funabashi et al. Nature Chemical Biology
- Novel 5′-deoxy nucleosyl amino acid scaffolds for the synthesis of muraymycin analogues
- (2010) Anatol P. Spork et al. ORGANIC & BIOMOLECULAR CHEMISTRY
- Structure–activity studies on novel polymyxin derivatives that carry only three positive charges
- (2010) Martti Vaara et al. PEPTIDES
- Rifamycins – Obstacles and opportunities
- (2010) Paul A. Aristoff et al. TUBERCULOSIS
- Thiopeptide Antibiotic Biosynthesis
- (2009) Hans-Dieter Arndt et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Activity of SQ641, a Capuramycin Analog, in a Murine Model of Tuberculosis
- (2009) B. V. Nikonenko et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Water-soluble phosphate prodrugs of pleuromutilin analogues with potent in vivo antibacterial activity against Gram-positive pathogens
- (2009) Liqiang Fu et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Biosynthesis of Indolocarbazole and Goadsporin, Two Different Heterocyclic Antibiotics Produced by Actinomycetes
- (2009) Hiroyasu ONAKA BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
- Analysis of the Liposidomycin Gene Cluster Leads to the Identification of New Caprazamycin Derivatives
- (2009) Leonard Kaysser et al. CHEMBIOCHEM
- The Structural Diversity of Acidic Lipopeptide Antibiotics
- (2009) Matthias Strieker et al. CHEMBIOCHEM
- Development of Des-Fatty Acyl-Polymyxin B Decapeptide Analogs with Pseudomonas aeruginosa-Specific Antimicrobial Activity
- (2009) Naoko Katsuma et al. CHEMICAL & PHARMACEUTICAL BULLETIN
- Novel Pleuromutilin Derivatives with Excellent Antibacterial Activity AgainstStaphylococcus aureus
- (2009) Peng Xu et al. Chemical Biology & Drug Design
- Thiopeptide Biosynthesis Featuring Ribosomally Synthesized Precursor Peptides and Conserved Posttranslational Modifications
- (2009) Rijing Liao et al. CHEMISTRY & BIOLOGY
- Daptomycin: mechanisms of action and resistance, and biosynthetic engineering
- (2009) Richard H Baltz CURRENT OPINION IN CHEMICAL BIOLOGY
- Colistin in the 21st century
- (2009) Roger L Nation et al. CURRENT OPINION IN INFECTIOUS DISEASES
- New screens and targets in antibacterial drug discovery
- (2009) Shannon B Falconer et al. CURRENT OPINION IN MICROBIOLOGY
- New information about the polymyxin/colistin class of antibiotics
- (2009) José Molina et al. EXPERT OPINION ON PHARMACOTHERAPY
- Tuberculosis pharmacotherapy: strategies to optimize patient care
- (2009) Carole D Mitnick et al. EXPERT OPINION ON PHARMACOTHERAPY
- Peptide deformylase – a promising therapeutic target for tuberculosis and antibacterial drug discovery
- (2009) Anshika Sharma et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Novel antimicrobial lipopeptides with long in vivo half-lives
- (2009) Chris J. Pasetka et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Rifalazil and Derivative Compounds Show Potent Efficacy in a Mouse Model of H. pylori Colonization
- (2009) David M Rothstein et al. JOURNAL OF ANTIBIOTICS
- Microbial drug discovery: 80 years of progress
- (2009) Arnold L Demain et al. JOURNAL OF ANTIBIOTICS
- Identification and Manipulation of the Caprazamycin Gene Cluster Lead to New Simplified Liponucleoside Antibiotics and Give Insights into the Biosynthetic Pathway
- (2009) Leonard Kaysser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novel Chemical Space Exploration via Natural Products
- (2009) Josefin Rosén et al. JOURNAL OF MEDICINAL CHEMISTRY
- Structure−Activity Relationships of Polymyxin Antibiotics
- (2009) Tony Velkov et al. JOURNAL OF MEDICINAL CHEMISTRY
- Antibiotics: Natural products essential to human health
- (2009) Arnold L. Demain MEDICINAL RESEARCH REVIEWS
- Mutilins Derivatives: From Veterinary to Human-used Antibiotics
- (2009) Changhua Hu et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Recent advances in thiopeptideantibiotic biosynthesis
- (2009) Chaoxuan Li et al. NATURAL PRODUCT REPORTS
- Antimicrobial nucleoside antibiotics targeting cell wall assembly: Recent advances in structure–function studies and nucleoside biosynthesis
- (2009) Michael Winn et al. NATURAL PRODUCT REPORTS
- Concise Synthesis of Capuramycin
- (2009) Michio Kurosu et al. ORGANIC LETTERS
- The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review
- (2009) K. M. S. Islam et al. POULTRY SCIENCE
- Antibiotics for Emerging Pathogens
- (2009) M. A. Fischbach et al. SCIENCE
- Manipulation of charged residues within the two-peptide lantibiotic lacticin 3147
- (2009) Lucy H. Deegan et al. Microbial Biotechnology
- Rifamycin Antibiotics for Treatment of Clostridium difficile–Associated Diarrhea
- (2008) Kevin W Garey et al. ANNALS OF PHARMACOTHERAPY
- In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Microbiology Profiling Studies with Staphylococci and Streptococci
- (2008) G. T. Robertson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- In Vitro Evaluation of CBR-2092, a Novel Rifamycin-Quinolone Hybrid Antibiotic: Studies of the Mode of Action in Staphylococcus aureus
- (2008) G. T. Robertson et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Novel Polymyxin Derivatives Carrying Only Three Positive Charges Are Effective Antibacterial Agents
- (2008) M. Vaara et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- New Drugs against Tuberculosis: Problems, Progress, and Evaluation of Agents in Clinical Development
- (2008) J. van den Boogaard et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Structure–activity relationship of truncated analogs of caprazamycins as potential anti-tuberculosis agents
- (2008) Shinpei Hirano et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Pleuromutilin derivatives having a purine ring. Part 1: New compounds with promising antibacterial activity against resistant Gram-positive pathogens
- (2008) Yoshimi Hirokawa et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Pleuromutilin derivatives having a purine ring. Part 3: Synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer
- (2008) Yoshimi Hirokawa et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Pleuromutilin derivatives having a purine ring. Part 2: Influence of the central spacer on the antibacterial activity against Gram-positive pathogens
- (2008) Yoshimi Hirokawa et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
- (2008) Helen W. Boucher et al. CLINICAL INFECTIOUS DISEASES
- Biosynthesis and Genetic Engineering of Lipopeptide Antibiotics Related to Daptomycin
- (2008) Richard Baltz CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Retapamulin
- (2008) Lily P H Yang et al. DRUGS
- Water-Soluble Pleuromutilin Derivative with Excellent in Vitro and in Vivo Antibacterial Activity against Gram-Positive Pathogens
- (2008) Yoshimi Hirokawa et al. JOURNAL OF MEDICINAL CHEMISTRY
- Mapping the Binding Site of Thiopeptide Antibiotics by Proximity-Induced Covalent Capture
- (2008) Sascha Baumann et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Natural products as an inspiration in the diversity-oriented synthesis of bioactive compound libraries
- (2008) Christopher Cordier et al. NATURAL PRODUCT REPORTS
- Scaffold diversity of natural products: inspiration for combinatorial library design
- (2008) Kristina Grabowski et al. NATURAL PRODUCT REPORTS
- Design and synthesis of diketopiperazine and acyclic analogs related to the caprazamycins and liposidomycins as potential antibacterial agents
- (2007) Shinpei Hirano et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Synthesis of Caprazamycin Analogues and Their Structure−Activity Relationship for Antibacterial Activity
- (2007) Shinpei Hirano et al. JOURNAL OF ORGANIC CHEMISTRY
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started