标题
Cytosolic phospholipase A2: physiological function and role in disease
作者
关键词
-
出版物
JOURNAL OF LIPID RESEARCH
Volume 56, Issue 8, Pages 1386-1402
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2015-04-03
DOI
10.1194/jlr.r057588
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- 5-Lipoxygenase, a key enzyme for leukotriene biosynthesis in health and disease
- (2015) Olof Rådmark et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The role of cytosolic phospholipase A2α in amyloid precursor protein induction by amyloid beta1-42: implication for neurodegeneration
- (2015) Chen Sagy-Bross et al. JOURNAL OF NEUROCHEMISTRY
- The role of PGE2 in intestinal inflammation and tumorigenesis
- (2015) David C. Montrose et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Cytosolic phospholipase A2protein as a novel therapeutic target for spinal cord injury
- (2014) Nai-Kui Liu et al. ANNALS OF NEUROLOGY
- Lysophosphatidic acid as a lipid mediator with multiple biological actions
- (2014) S. Aikawa et al. JOURNAL OF BIOCHEMISTRY
- A Cyclooxygenase-2-dependent Prostaglandin E2Biosynthetic System in the Golgi Apparatus
- (2014) Chong Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytosolic phospholipase A2 drives recycling through the clathrin-independent endocytic route
- (2014) M. Capestrano et al. JOURNAL OF CELL SCIENCE
- Modulation of Lipid and Protein Mediators of Inflammation by Cytosolic Phospholipase A2 during Experimental Sepsis
- (2014) N. Uozumi et al. JOURNAL OF IMMUNOLOGY
- To hydrolyze or not to hydrolyze: the dilemma of platelet-activating factor acetylhydrolase
- (2014) Gopal Kedihitlu Marathe et al. JOURNAL OF LIPID RESEARCH
- Long-Term Potentiation at Cerebellar Parallel Fiber-Purkinje Cell Synapses Requires Presynaptic and Postsynaptic Signaling Cascades
- (2014) D.-J. Wang et al. JOURNAL OF NEUROSCIENCE
- Protective Effect of Cytosolic Phospholipase A2 Inhibition against Inflammation and Degeneration by Promoting Regulatory T Cells in Rats with Experimental Autoimmune Encephalomyelitis
- (2014) Dan Yang et al. MEDIATORS OF INFLAMMATION
- Lysophosphatidic Acid Signaling in Late Cleavage and Blastocyst Stage Bovine Embryos
- (2014) Ana Catarina Torres et al. MEDIATORS OF INFLAMMATION
- Phospholipase A2 regulates eicosanoid class switching during inflammasome activation
- (2014) P. C. Norris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bleeding diathesis and gastro-duodenal ulcers in inherited cytosolic phospholipase-A2 alpha deficiency
- (2014) Elena Faioni et al. THROMBOSIS AND HAEMOSTASIS
- Predominant Role of Cytosolic Phospholipase A2α in Dioxin-induced Neonatal Hydronephrosis in Mice
- (2014) Wataru Yoshioka et al. Scientific Reports
- PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis
- (2013) Susanne Schiffmann et al. BIOCHEMICAL PHARMACOLOGY
- An Inflammatory Mediator, Prostaglandin E2, in Colorectal Cancer
- (2013) Dingzhi Wang et al. CANCER JOURNAL
- Retrograde cPLA2α/Arachidonic Acid/2-AG Signaling Is Essential for Cerebellar Depolarization-Induced Suppression of Excitation and Long-Term Potentiation
- (2013) Li-Da Su et al. CEREBELLUM
- Lactosylceramide Interacts with and Activates Cytosolic Phospholipase A2α
- (2013) Hiroyuki Nakamura et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cytosolic Group IVA and Calcium-Independent Group VIA Phospholipase A2s Act on Distinct Phospholipid Pools in Zymosan-Stimulated Mouse Peritoneal Macrophages
- (2013) L. Gil-de-Gomez et al. JOURNAL OF IMMUNOLOGY
- A distal enhancer controls cytokine-dependent human cPLA2α gene expression
- (2013) Justin S. Bickford et al. JOURNAL OF LIPID RESEARCH
- An Off–On COX-2-Specific Fluorescent Probe: Targeting the Golgi Apparatus of Cancer Cells
- (2013) Hua Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Cytosolic Phospholipase A2α and Eicosanoids Regulate Expression of Genes in Macrophages Involved in Host Defense and Inflammation
- (2013) Saritha Suram et al. PLoS One
- Cytosolic PhospholipaseA2 Inhibition with PLA-695 Radiosensitizes Tumors in Lung Cancer Animal Models
- (2013) Dinesh Thotala et al. PLoS One
- The Role of Anti-Inflammatory Drugs in Colorectal Cancer
- (2012) Dingzhi Wang et al. Annual Review of Medicine
- Regulation of the Golgi complex by phospholipid remodeling enzymes
- (2012) Kevin D. Ha et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Lysophosphatidylinositol signalling: New wine from an old bottle
- (2012) Roberto Piñeiro et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Inhibition of cytosolic Phospholipase A2 prevents prion peptide-induced neuronal damage and co-localisation with Beta III Tubulin
- (2012) Victoria Last et al. BMC NEUROSCIENCE
- cPLA2α knockout mice exhibit abnormalities in the architecture and synapses of cortical neurons
- (2012) Bao-Xi Qu et al. BRAIN RESEARCH
- Antisense inhibition of phospholipase A2
- (2012) Lhousseine Touqui CRITICAL CARE MEDICINE
- Antisense inhibition of secretory and cytosolic phospholipase A2 reduces the mortality in rats with sepsis*
- (2012) Maw-Shung Liu et al. CRITICAL CARE MEDICINE
- Group IVA phospholipase A2 optimizes ovulation and fertilization in rodents through induction of and metabolic coupling with prostaglandin endoperoxide synthase 2
- (2012) Shiro Kurusu et al. FASEB JOURNAL
- Group IVA phospholipase A2 participates in the progression of hepatic fibrosis
- (2012) Keiichi Ishihara et al. FASEB JOURNAL
- Cryptogenic multifocal ulcerating stenosing enteritis associated with homozygous deletion mutations in cytosolic phospholipase A2-α
- (2012) Matthew A Brooke et al. GUT
- The nuclear membrane leukotriene synthetic complex is a signal integrator and transducer
- (2012) Angela M. Bair et al. MOLECULAR BIOLOGY OF THE CELL
- Integrating Cytosolic Phospholipase A2 with Oxidative/Nitrosative Signaling Pathways in Neurons: A Novel Therapeutic Strategy for AD
- (2012) Grace Y. Sun et al. MOLECULAR NEUROBIOLOGY
- Mechanisms of fibrosis: therapeutic translation for fibrotic disease
- (2012) Thomas A Wynn et al. NATURE MEDICINE
- Emerging roles for lysophosphatidylserine in resolution of inflammation
- (2012) S. Courtney Frasch et al. PROGRESS IN LIPID RESEARCH
- A PLA1-2 punch regulates the Golgi complex
- (2012) Marie E. Bechler et al. TRENDS IN CELL BIOLOGY
- Prostaglandins and chronic inflammation
- (2012) Tomohiro Aoki et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Prostaglandin E2and the Pathogenesis of Pulmonary Fibrosis
- (2011) Paul D. Bozyk et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Cytosolic Phospholipase A 2 α Contributes to Blood Pressure Increases and Endothelial Dysfunction Under Chronic NO Inhibition
- (2011) Kohei Tanaka et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Prostaglandins and Inflammation
- (2011) Emanuela Ricciotti et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Group IVA phospholipase A2regulates testosterone biosynthesis by murine Leydig cells and is required for timely sexual maturation
- (2011) Shiro Kurusu et al. BIOCHEMICAL JOURNAL
- Functional Characterization of Mutations in Inherited Human cPLA2Deficiency
- (2011) Kathleen A. Reed et al. BIOCHEMISTRY
- Enzymes of the Cyclooxygenase Pathways of Prostanoid Biosynthesis
- (2011) William L. Smith et al. CHEMICAL REVIEWS
- Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
- (2011) Edward A. Dennis et al. CHEMICAL REVIEWS
- Lysophosphatidic acid-1-receptor targeting agents for fibrosis
- (2011) Chloé Rancoule et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Phospholipase A2 superfamily members play divergent roles after spinal cord injury
- (2011) Rubèn López-Vales et al. FASEB JOURNAL
- Analysis of Two Major Intracellular Phospholipases A2(PLA2) in Mast Cells Reveals Crucial Contribution of Cytosolic PLA2α, Not Ca2+-independent PLA2β, to Lipid Mobilization in Proximal Mast Cells and Distal Fibroblasts
- (2011) Noriko Ueno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Critical role of cPLA2 in Aβ oligomer-induced neurodegeneration and memory deficit
- (2011) Cédric Desbène et al. NEUROBIOLOGY OF AGING
- International Union of Basic and Clinical Pharmacology. LXXXIII: Classification of Prostanoid Receptors, Updating 15 Years of Progress
- (2011) D. F. Woodward et al. PHARMACOLOGICAL REVIEWS
- Localization and function of cytosolic phospholipase A2α at the Golgi
- (2010) Christina C. Leslie et al. BIOCHIMIE
- The role of mast cell-derived secreted phospholipases A2 in respiratory allergy
- (2010) Francescopaolo Granata et al. BIOCHIMIE
- Cytosolic phospholipase A2 group IVA is overexpressed in patients with persistent asthma and regulated by the promoter microsatellites
- (2010) Milena Sokolowska et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Interfacial Kinetic and Binding Properties of Mammalian Group IVB Phospholipase A2(cPLA2β) and Comparison with the Other cPLA2Isoforms
- (2010) Farideh Ghomashchi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Role of Kruppel-like Factor 11 in the Regulation of Prostaglandin E2Biosynthesis
- (2010) Navtej S. Buttar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells
- (2010) Chiang-Wen Lee et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Evidence for De Novo Synthesis of Lysophosphatidic Acid in the Spinal Cord through Phospholipase A2 and Autotaxin in Nerve Injury-Induced Neuropathic Pain
- (2010) L. Ma et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Cytosolic Phospholipase A2 and Lysophospholipids in Tumor Angiogenesis
- (2010) A. G. Linkous et al. JNCI-Journal of the National Cancer Institute
- Induction of GαsContributes to the Paradoxical Stimulation of Cytosolic Phospholipase A2αExpression by Cortisol in Human Amnion Fibroblasts
- (2010) Chunming Guo et al. MOLECULAR ENDOCRINOLOGY
- Phospholipase A2 inhibitors protect against prion and Aβ mediated synapse degeneration
- (2010) Clive Bate et al. Molecular Neurodegeneration
- Lipid signaling in cytosolic phospholipase A2 -cyclooxygenase-2 cascade mediates cerebellar long-term depression and motor learning
- (2010) T. D. Le et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Group XV phospholipase A2, a lysosomal phospholipase A2
- (2010) James A. Shayman et al. PROGRESS IN LIPID RESEARCH
- Recent progress in phospholipase A2 research: From cells to animals to humans
- (2010) Makoto Murakami et al. PROGRESS IN LIPID RESEARCH
- cPLA2 Is Protective Against COX Inhibitor–Induced Intestinal Damage
- (2010) David C. Montrose et al. TOXICOLOGICAL SCIENCES
- TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys
- (2009) Bin Dong et al. BIOCHEMICAL PHARMACOLOGY
- Restoration of On-Time Embryo Implantation Corrects the Timing of Parturition in Cytosolic Phospholipase A2 Group IVA Deficient Mice1
- (2009) Naoko Brown et al. BIOLOGY OF REPRODUCTION
- Depletion of Cytosolic Phospholipase A2 in Bone Marrow-Derived Macrophages Protects against Lung Cancer Progression and Metastasis
- (2009) M. C.M. Weiser-Evans et al. CANCER RESEARCH
- Cytosolic Phospholipase A2: Targeting Cancer through the Tumor Vasculature
- (2009) A. Linkous et al. CLINICAL CANCER RESEARCH
- High-throughput evaluation of aryl hydrocarbon receptor-binding sites selected via chromatin immunoprecipitation-based screening in Hepa-1c1c7 cells stimulated with 2,3,7,8-tetrachlorodibenzo-p-dioxin
- (2009) Masaki Kinehara et al. GENES & GENETIC SYSTEMS
- CCR2 promotes hepatic fibrosis in mice
- (2009) Ekihiro Seki et al. HEPATOLOGY
- Role of Phosphorylation and Basic Residues in the Catalytic Domain of Cytosolic Phospholipase A2α in Regulating Interfacial Kinetics and Binding and Cellular Function
- (2009) Dawn E. Tucker et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Ceramide 1-Phosphate Is Required for the Translocation of Group IVA Cytosolic Phospholipase A2and Prostaglandin Synthesis
- (2009) Nadia F. Lamour et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- JNK and Ceramide Kinase Govern the Biogenesis of Lipid Droplets through Activation of Group IVA Phospholipase A2
- (2009) Albert Gubern et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aryl hydrocarbon receptor-mediated induction of the cytosolic phospholipase A2α gene by 2,3,7,8-tetrachlorodibenzo-p-dioxin in mouse hepatoma Hepa-1c1c7 cells
- (2009) Masaki Kinehara et al. JOURNAL OF BIOSCIENCE AND BIOENGINEERING
- Requirement of JNK-Mediated Phosphorylation for Translocation of Group IVA Phospholipase A2 to Phagosomes in Human Macrophages
- (2009) J. Casas et al. JOURNAL OF IMMUNOLOGY
- Golgi-associated cPLA2α Regulates Endothelial Cell–Cell Junction Integrity by Controlling the Trafficking of Transmembrane Junction Proteins
- (2009) Elsa Regan-Klapisz et al. MOLECULAR BIOLOGY OF THE CELL
- Phospholipases A2 and Inflammatory Responses in the Central Nervous System
- (2009) Grace Y. Sun et al. NEUROMOLECULAR MEDICINE
- COX-2-mediated Inflammation in Fat Is Crucial for Obesity-linked Insulin Resistance and Fatty Liver
- (2009) Po-Shiuan Hsieh et al. Obesity
- The role of COX-2 in intestinal inflammation and colorectal cancer
- (2009) D Wang et al. ONCOGENE
- Alleviation of High-Fat Diet-Induced Fatty Liver Damage in Group IVA Phospholipase A2-Knockout Mice
- (2009) Hiromi Ii et al. PLoS One
- Emerging roles of PGE2 receptors in models of neurological disease
- (2009) Katrin Andreasson PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Group IV Phospholipase A2α Controls the Formation of Inter-Cisternal Continuities Involved in Intra-Golgi Transport
- (2009) Enrica San Pietro et al. PLOS BIOLOGY
- Biochemistry and Physiology of Mammalian Secreted Phospholipases A2
- (2008) Gérard Lambeau et al. Annual Review of Biochemistry
- The significance of the nongenomic pathway in mediating inflammatory signaling of the dioxin-activated Ah receptor to cause toxic effects
- (2008) Fumio Matsumura BIOCHEMICAL PHARMACOLOGY
- Two pathways for lysophosphatidic acid production
- (2008) J AOKI BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Biology of Platelet-activating Factor Acetylhydrolase (PAF-AH, Lipoprotein Associated Phospholipase A2)
- (2008) Diana M. Stafforini CARDIOVASCULAR DRUGS AND THERAPY
- Cytosolic phospholipase A2 regulates viability of irradiated vascular endothelium
- (2008) E M Yazlovitskaya et al. CELL DEATH AND DIFFERENTIATION
- In vitro allergen challenge of peripheral blood induces differential gene expression in mononuclear cells of asthmatic patients: inhibition of cytosolic phospholipase A2α overcomes the asthma-associated response
- (2008) K. A. Whalen et al. CLINICAL AND EXPERIMENTAL ALLERGY
- A Phospholipid Substrate Molecule Residing in the Membrane Surface Mediates Opening of the Lid Region in Group IVA Cytosolic Phospholipase A2
- (2008) John E. Burke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- cPLA2phosphorylation at serine-515 and serine-505 is required for arachidonic acid release in vascular smooth muscle cells
- (2008) Zoran Pavicevic et al. JOURNAL OF LIPID RESEARCH
- Indole Cytosolic Phospholipase A2α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib
- (2008) John C. McKew et al. JOURNAL OF MEDICINAL CHEMISTRY
- Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2in cortical neurons
- (2008) Phullara B. Shelat et al. JOURNAL OF NEUROCHEMISTRY
- Blockade of cytosolic phospholipase A2α prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses
- (2008) S MARUSIC et al. JOURNAL OF NEUROIMMUNOLOGY
- Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
- (2008) Rene O Sanchez-Mejia et al. NATURE NEUROSCIENCE
- The nuclear membrane organization of leukotriene synthesis
- (2008) A. K. Mandal et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Group IVA phospholipase A2 is associated with the storage of lipids in adipose tissue and liver
- (2008) Hiromi Ii et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Critical role of cyclooxygenase-2 activation in pathogenesis of hydronephrosis caused by lactational exposure of mice to dioxin
- (2008) N NISHIMURA et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- What's all the FLAP about?: 5-lipoxygenase-activating protein inhibitors for inflammatory diseases
- (2008) J EVANS et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Paradox of Glucocorticoid-Induced Cytosolic Phospholipase A2 Group IVA Messenger RNA Expression Involves Glucocorticoid Receptor Binding to the Promoter in Human Amnion Fibroblasts1
- (2007) Chunming Guo et al. BIOLOGY OF REPRODUCTION
- Cellular and molecular mechanisms of fibrosis
- (2007) TA Wynn JOURNAL OF PATHOLOGY
- Roles of ERK and cPLA2 in the Angiotensin II-Mediated Biphasic Regulation of Na+-HCO3- Transport
- (2007) Y. Li et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search