Effects of microgravity on DNA damage response in Caenorhabditis elegans during Shenzhou-8 spaceflight

Down regulation of miR-124 in both Werner syndrome DNA helicase mutant mice and mutant Caenorhabditis elegans wrn-1 reveals the importance of this microRNA in accelerated aging

(2016) Alexandra Dallaire et al.   Aging-US

Biological and metabolic response in STS-135 space-flown mouse skin

(2014) X. W. Mao et al.   FREE RADICAL RESEARCH

Signal transduction in primary human T lymphocytes in altered gravity – results of the MASER-12 suborbital space flight mission

(2013) Svantje Tauber et al.   Cell Communication and Signaling

The challenging environment on board the International Space Station affects endothelial cell function by triggering oxidative stress through thioredoxin interacting protein overexpression: the ESA-SPHINX experiment

(2013) Silvia Versari et al.   FASEB JOURNAL

The shelterin protein POT-1 anchorsCaenorhabditis eleganstelomeres through SUN-1 at the nuclear periphery

(2013) Helder C. Ferreira et al.   JOURNAL OF CELL BIOLOGY

MicroRNA-124 (miR-124) Regulates Ku70 Expression and is Correlated with Neuronal Death Induced by Ischemia/Reperfusion

(2013) Fei Zhu et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

miR-124 radiosensitizes human glioma cells by targeting CDK4

(2013) Xubin Deng et al.   JOURNAL OF NEURO-ONCOLOGY

Modulation of Pleurodeles waltl DNA Polymerase mu Expression by Extreme Conditions Encountered during Spaceflight

(2013) Véronique Schenten et al.   PLoS One

Regulation of protein translation initiation in response to ionizing radiation

(2013) Donatella Trivigno et al.   Radiation Oncology

Divergent Modification of Low-Dose56Fe-Particle and Proton Radiation on Skeletal Muscle

(2013) Alexander Shtifman et al.   RADIATION RESEARCH

MicroRNA-143 is downregulated in breast cancer and regulates DNA methyltransferases 3A in breast cancer cells

(2013) Enders K. O. Ng et al.   TUMOR BIOLOGY

MicroRNA-143 suppresses gastric cancer cell growth and induces apoptosis by targeting COX-2

(2013) Xiao-Li Wu   WORLD JOURNAL OF GASTROENTEROLOGY

Noncanonical control of C. elegans germline apoptosis by the insulin/IGF-1 and Ras/MAPK signaling pathways

(2012) A J Perrin et al.   CELL DEATH AND DIFFERENTIATION

Programmed cell death in C. elegans, mammals and plants

(2012) Christina E.N. Lord et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Expression of p53-Regulated Proteins in Human Cultured Lymphoblastoid TSCE5 and WTK1 Cell Lines during Spaceflight

(2012) Akihisa TAKAHASHI et al.   JOURNAL OF RADIATION RESEARCH

Analysis of the combined action of miR-143 and miR-145 on oncogenic pathways in colorectal cancer cells reveals a coordinate program of gene repression

(2012) A Pagliuca et al.   ONCOGENE

Analysis of miRNA and mRNA Expression Profiles Highlights Alterations in Ionizing Radiation Response of Human Lymphocytes under Modeled Microgravity

(2012) Cristina Girardi et al.   PLoS One

DNA Repair Genes: Alternative Transcription and Gene Expression at the Exon Level in Response to the DNA Damaging Agent, Ionizing Radiation

(2012) Helen B. Forrester et al.   PLoS One

Genes down-regulated in spaceflight are involved in the control of longevity in Caenorhabditis elegans

(2012) Yoko Honda et al.   Scientific Reports

microRNA-143 Protects Cells from DNA Damage-Induced Killing by Downregulating FHIT Expression

(2011) Yu-xiang Lin et al.   CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS

Effects of Simulated Microgravity on Expression Profile of MicroRNA in Human Lymphoblastoid Cells

(2011) Lingegowda S. Mangala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biological Effects of Space Radiation on Human Cells: History, Advances and Outcomes

(2011) Mira MAALOUF et al.   JOURNAL OF RADIATION RESEARCH

Remote automated multi-generational growth and observation of an animal in low Earth orbit

(2011) E. A. Oczypok et al.   Journal of the Royal Society Interface

MicroRNAs, the DNA damage response and cancer

(2011) Maikel D. Wouters et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Effects of Simulated Microgravity on Embryonic Stem Cells

(2011) Yulan Wang et al.   PLoS One

DNA double-strand break repair in Caenorhabditis elegans

(2010) Bennie B. L. G. Lemmens et al.   CHROMOSOMA

Space Microbiology

(2010) G. Horneck et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Frozen human cells can record radiation damage accumulated during space flight: mutation induction and radioadaptation

(2010) Fumio Yatagai et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Simulated microgravity decreases DNA repair capacity and induces DNA damage in human lymphocytes

(2009) Ragini Kumari et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The mir-34 microRNA is required for the DNA damage response in vivo in C. elegans and in vitro in human breast cancer cells

(2009) M Kato et al.   ONCOGENE

Heavy ions, radioprotectors and genomic instability: implications for human space exploration

(2009) Jaroslaw Dziegielewski et al.   RADIATION AND ENVIRONMENTAL BIOPHYSICS

Description of International Caenorhabditis elegans Experiment first flight (ICE-FIRST)

(2008) N.J. Szewczyk et al.   ADVANCES IN SPACE RESEARCH

Transcriptional profiling in C. elegans suggests DNA damage dependent apoptosis as an ancient function of the p53 family

(2008) Sebastian Greiss et al.   BMC GENOMICS

Formation of Clustered DNA Damage after High-LET Irradiation: A Review

(2008) Megumi HADA et al.   JOURNAL OF RADIATION RESEARCH

Spaceflight results in increase of thick filament but not thin filament proteins in the paramyosin mutant of Caenorhabditis elegans

(2007) R. Adachi et al.   ADVANCES IN SPACE RESEARCH

Genomic response of the nematode Caenorhabditis elegans to spaceflight

(2007) Florian Selch et al.   ADVANCES IN SPACE RESEARCH