The challenging environment on board the International Space Station affects endothelial cell function by triggering oxidative stress through thioredoxin interacting protein overexpression: the ESA-SPHINX experiment

Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases

(2012) Antero Salminen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Thioredoxin Interacting Protein Promotes Endothelial Cell Inflammation in Response to Disturbed Flow by Increasing Leukocyte Adhesion and Repressing Kruppel-Like Factor 2

(2012) Xiao-Qun Wang et al.   CIRCULATION RESEARCH

Molecular force transduction by ion channels – diversity and unifying principles

(2012) Sergei Sukharev et al.   JOURNAL OF CELL SCIENCE

Mechanosensitive mechanisms in transcriptional regulation

(2012) Akiko Mammoto et al.   JOURNAL OF CELL SCIENCE

Endothelial dysfunction as a cellular mechanism for vascular failure

(2011) Tetsuaki Hirase et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative Stress–Induced Degradation of Thioredoxin-1 and Apoptosis Is Inhibited by Thioredoxin-1–Actin Interaction in Endothelial Cells

(2011) Tim-Christian Zschauer et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Thioredoxin-Interacting Protein Mediates TRX1 Translocation to the Plasma Membrane in Response to Tumor Necrosis Factor-α

(2011) Cameron World et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proliferative versus apoptotic functions of caspase-8

(2011) Bram J. van Raam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Short-term weightlessness produced by parabolic flight maneuvers altered gene expression patterns in human endothelial cells

(2011) Jirka Grosse et al.   FASEB JOURNAL

Osmosensory Mechanisms in Cellular and Systemic Volume Regulation

(2011) S. F. Pedersen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Role of shear stress and stretch in vascular mechanobiology

(2011) D. Lu et al.   Journal of the Royal Society Interface

Dynamic molecular processes mediate cellular mechanotransduction

(2011) Brenton D. Hoffman et al.   NATURE

Balancing forces: architectural control of mechanotransduction

(2011) Christopher C. DuFort et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Role of cellular mechanics in the function and life span of vascular endothelium

(2011) Katrin Kliche et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives

(2011) Jeng-Jiann Chiu et al.   PHYSIOLOGICAL REVIEWS

The Emerging Role of the Thioredoxin System in Angiogenesis

(2010) Louise L. Dunn et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Oxidative stress and alterations in actin cytoskeleton trigger glutathione efflux in Saccharomyces cerevisiae

(2010) Silvia Bradamante et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

Hemodynamic forces in endothelial dysfunction and vascular aging

(2010) Caitlin Collins et al.   EXPERIMENTAL GERONTOLOGY

Mechanisms of mechanical signaling in development and disease

(2010) P. A. Janmey et al.   JOURNAL OF CELL SCIENCE

Modification of proteins secreted by endothelial cells during modeled low gravity exposure

(2010) Cristiana Griffoni et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The emerging roles of microRNAs in the molecular responses of metabolic rate depression

(2010) K. K. Biggar et al.   Journal of Molecular Cell Biology

Effect of aging on cellular mechanotransduction

(2009) Miaozong Wu et al.   AGEING RESEARCH REVIEWS

MicroRNAs: a complex regulatory network drives the acquisition of malignant cell phenotype

(2009) Libero Santarpia et al.   ENDOCRINE-RELATED CANCER

Apoptomirs: small molecules have gained the license to kill

(2009) Andrea Vecchione et al.   ENDOCRINE-RELATED CANCER

Space, Gravity and the Physiology of Aging: Parallel or Convergent Disciplines? A Mini-Review

(2009) Joan Vernikos et al.   GERONTOLOGY

Human Caspases: Activation, Specificity, and Regulation

(2009) Cristina Pop et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Micro- and Macrovascular Endothelial Cells Exposed to Simulated Microgravity Upregulate hsp70

(2009) M. Mariotti et al.   MICROGRAVITY SCIENCE AND TECHNOLOGY

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

ROS and p53: A versatile partnership

(2008) Bin Liu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mechanotransduction gone awry

(2008) Diana E. Jaalouk et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY