Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis

Beauvericin Potentiates Azole Activity via Inhibition of Multidrug Efflux, BlocksC. albicansMorphogenesis, and is Effluxed via Yor1 and Circuitry Controlled by Zcf29

(2016) Tanvi Shekhar-Guturja et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Synergistic Effect of Azoles and Fluoxetine against Resistant Candida albicans Strains Is Attributed to Attenuating Fungal Virulence

(2016) Wenrui Gu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Epidemiology and Molecular Characterizations of Azole Resistance in Clinical and Environmental Aspergillus fumigatus Isolates from China

(2016) Yong Chen et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Aspergillus fumigatus Intrinsic Fluconazole Resistance Is Due to the Naturally Occurring T301I Substitution in Cyp51Ap

(2016) Florencia Leonardelli et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The synthesis and synergistic antifungal effects of chalcones against drug resistant Candida albicans

(2016) Yuan-Hua Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Time to overcome fluconazole resistant Candida isolates: Solid lipid nanoparticles as a novel antifungal drug delivery system

(2016) Maryam Moazeni et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Synthesis, antifungal activity of caffeic acid derivative esters, and their synergism with fluconazole and nystatin against Candida spp.

(2016) Janaína de Cássia Orlandi Sardi et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Strategies in the discovery of novel antifungal scaffolds

(2016) Na Liu et al.   Future Medicinal Chemistry

Evolutionary history of the chitin synthases of eukaryotes

(2016) Alexey A Morozov et al.   GLYCOBIOLOGY

Synergy and antagonism between iron chelators and antifungal drugs in Cryptococcus

(2016) Yu-Wen Lai et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Evaluation of the efficacy of antifungal drugs against Paracoccidioides brasiliensis and Paracoccidioides lutzii in a Galleria mellonella model

(2016) Junya de Lacorte Singulani et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Synergistic effect of pedalitin and amphotericin B against Cryptococcus neoformans by in vitro and in vivo evaluation

(2016) Fernanda Sangalli-Leite et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Fungal diseases: could nanostructured drug delivery systems be a novel paradigm for therapy?

(2016) Aline Voltan et al.   International Journal of Nanomedicine

Pathogenicity of Candida albicans isolates from bloodstream and mucosal candidiasis assessed in mice and Galleria mellonella

(2016) M. Frenkel et al.   JOURNAL DE MYCOLOGIE MEDICALE

Compensatory expression of multidrug-resistance genes encoding ABC transporters in dermatophytes

(2016) Maíra Pompeu Martins et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Analysis of Sporothrix schenckii sensu stricto and Sporothrix brasiliensis virulence in Galleria mellonella

(2016) Diana M. Clavijo-Giraldo et al.   JOURNAL OF MICROBIOLOGICAL METHODS

Azole Resistance in Dermatophytes

(2016) Mahmoud Ghannoum   JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION

Amphotericin B-conjugated biogenic silver nanoparticles as an innovative strategy for fungal infections

(2016) Aftab Ahmad et al.   MICROBIAL PATHOGENESIS

Epidemiology and molecular mechanisms of antifungal resistance in CandidaandAspergillus

(2016) Sarah Santos Gonçalves et al.   MYCOSES

Magnetic nanoparticles as a drug delivery system that enhance fungicidal activity of polyene antibiotics

(2016) Katarzyna Niemirowicz et al.   Nanomedicine-Nanotechnology Biology and Medicine

Glucosylceramide Administration as a Vaccination Strategy in Mouse Models of Cryptococcosis

(2016) Visesato Mor et al.   PLoS One

Synergistic Effect of Fluconazole and Calcium Channel Blockers against Resistant Candida albicans

(2016) Shuyuan Liu et al.   PLoS One

Amino acid substitution in Cryptococcus neoformans lanosterol 14-α-demethylase involved in fluconazole resistance in clinical isolates

(2016) María E. Bosco-Borgeat et al.   REVISTA ARGENTINA DE MICROBIOLOGIA

A complex game of hide and seek: the search for new antifungals

(2016) Huy X. Ngo et al.   MedChemComm

The Aspergillus fumigatus Damage Resistance Protein Family Coordinately Regulates Ergosterol Biosynthesis and Azole Susceptibility

(2016) Jinxing Song et al.   mBio

Lipid Flippase Subunit Cdc50 Mediates Drug Resistance and Virulence in Cryptococcus neoformans

(2016) Wei Huang et al.   mBio

Phenotypic switching ofCandida tropicalisis associated with cell damage in epithelial cells and virulence inGalleria mellonellamodel

(2016) Alane T.-P. Moralez et al.   Virulence

Calcineurin in fungal virulence and drug resistance: Prospects for harnessing targeted inhibition of calcineurin for an antifungal therapeutic approach

(2016) Praveen R. Juvvadi et al.   Virulence

Triclosan Demonstrates Synergic Effect with Amphotericin B and Fluconazole and Induces Apoptosis-Like Cell Death in Cryptococcus neoformans

(2016) Elaheh Movahed et al.   Frontiers in Microbiology

Virulence of Cryptococcus sp. Biofilms In Vitro and In Vivo using Galleria mellonella as an Alternative Model

(2016) Tatiane Benaducci et al.   Frontiers in Microbiology

Combination Antifungal Therapy for Invasive Aspergillosis

(2015) Kieren A. Marr et al.   ANNALS OF INTERNAL MEDICINE

Blocking Hsp70 Enhances the Efficiency of Amphotericin B Treatment against Resistant Aspergillus terreus Strains

(2015) Michael Blatzer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms andIn VivoImpact in Infected Galleria mellonella Larvae

(2015) Ana Carolina R. Souza et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapy

(2015) Li Zhang et al.   BMC INFECTIOUS DISEASES

Echinocandin Resistance in Candida

(2015) David S. Perlin   CLINICAL INFECTIOUS DISEASES

Caspofungin: Pharmacodynamics, pharmacokinetics, clinical uses and treatment outcomes

(2015) Jessica C. Song et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Recent Advances in Nanoparticle Carriers for Coordination Complexes

(2015) Mariana Sato et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Whole animal HTS of small molecules for antifungal compounds

(2015) Maged Muhammed et al.   Expert Opinion on Drug Discovery

Azole antifungals: 35 years of invasive fungal infection management

(2015) David Allen et al.   Expert Review of Anti-Infective Therapy

Clinical experience of the use of voriconazole, caspofungin or the combination in primary and salvage therapy of invasive aspergillosis in haematological malignancies

(2015) Issam I. Raad et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Identification and properties of plasma membrane azole efflux pumps from the pathogenic fungiCryptococcus gattiiandCryptococcus neoformans

(2015) Luiz R. Basso et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

New insights on the development of fungal vaccines: from immunity to recent challenges

(2015) Natasha P Medici et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Zebrafish as tools for drug discovery

(2015) Calum A. MacRae et al.   NATURE REVIEWS DRUG DISCOVERY

Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion

(2015) Jennifer L. Tenor et al.   mBio

Comparison of virulence betweenParacoccidioides brasiliensisandParacoccidioides lutziiusingGalleria mellonellaas a host model

(2015) Liliana Scorzoni et al.   Virulence

In vitro Paracoccidioides brasiliensisbiofilm and gene expression of adhesins and hydrolytic enzymes

(2015) Janaina de Cássia Orlandi Sardi et al.   Virulence

Vaccines in the treatment of invasive candidiasis

(2015) Xiao-juan Wang et al.   Virulence

Adaptation to thermotolerance inRhizopuscoincides with virulence as revealed by avian and invertebrate infection models, phylogeny, physiological and metabolic flexibility

(2015) Kerstin Kaerger et al.   Virulence

Heat Shock Protein 90 (Hsp90) as a Molecular Target for the Development of Novel Drugs Against the Dermatophyte Trichophyton rubrum

(2015) Tiago R. Jacob et al.   Frontiers in Microbiology

Role of Sterylglucosidase 1 (Sgl1) on the pathogenicity of Cryptococcus neoformans: potential applications for vaccine development

(2015) Antonella Rella et al.   Frontiers in Microbiology

Inhibitors of the Candida albicans Major Facilitator Superfamily Transporter Mdr1p Responsible for Fluconazole Resistance

(2015) Mikhail V. Keniya et al.   PLoS One

Zebrafish Egg Infection Model for Studying Candida albicans Adhesion Factors

(2015) Yin-Zhi Chen et al.   PLoS One

The Production of Reactive Oxygen Species Is a Universal Action Mechanism of Amphotericin B against Pathogenic Yeasts and Contributes to the Fungicidal Effect of This Drug

(2014) Ana Cecilia Mesa-Arango et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Synergistic Activity of the Tyrocidines, Antimicrobial Cyclodecapeptides from Bacillus aneurinolyticus, with Amphotericin B and Caspofungin against Candida albicans Biofilms

(2014) Anscha Mari Troskie et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VivoandIn VitroAcquisition of Resistance to Voriconazole by Candida krusei

(2014) Elisabete Ricardo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In VitroCombination of Isavuconazole with Micafungin or Amphotericin B Deoxycholate against Medically Important Molds

(2014) Aspasia Katragkou et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Mechanisms of Fluconazole Resistance in Candida parapsilosis Isolates from a U.S. Surveillance System

(2014) Nina T. Grossman et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multilaboratory Study of Epidemiological Cutoff Values for Detection of Resistance in Eight Candida Species to Fluconazole, Posaconazole, and Voriconazole

(2014) A. Espinel-Ingroff et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

In vitrocharacterization ofTrichophyton rubrumandT. mentagrophytesbiofilms

(2014) C.B. Costa-Orlandi et al.   BIOFOULING

Assessment of in vivo antimicrobial activity of the carbene silver(I) acetate derivative SBC3 using Galleria mellonella larvae

(2014) Niall Browne et al.   BIOMETALS

Anti-TrichophytonActivity of Protocatechuates and Their Synergism with Fluconazole

(2014) Luciana Arantes Soares et al.   Evidence-based Complementary and Alternative Medicine

Inhibitory effect of verapamil onCandida albicanshyphal development, adhesion and gastrointestinal colonization

(2014) Qilin Yu et al.   FEMS YEAST RESEARCH

Elucidating drug resistance in human fungal pathogens

(2014) Jinglin Lucy Xie et al.   Future Microbiology

Exploring azole antifungal drug resistance in Aspergillus fumigatus with special reference to resistance mechanisms

(2014) Anuradha Chowdhary et al.   Future Microbiology

Multi-azole-resistant Aspergillus fumigatus in the environment in Tanzania

(2014) A. Chowdhary et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

A Multi-Host Approach for the Systematic Analysis of Virulence Factors inCryptococcus neoformans

(2014) Athanasios Desalermos et al.   JOURNAL OF INFECTIOUS DISEASES

An opportunistic human pathogen on the fly: Strains of Aspergillus flavus vary in virulence in Drosophila melanogaster

(2014) L. A. Ramirez-Camejo et al.   MEDICAL MYCOLOGY

Candida parapsilosis complex water isolates from a haemodialysis unit: biofilm production and in vitro evaluation of the use of clinical antifungals

(2014) Regina Helena Pires et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Amphotericin forms an extramembranous and fungicidal sterol sponge

(2014) Thomas M Anderson et al.   Nature Chemical Biology

ASDCD: Antifungal Synergistic Drug Combination Database

(2014) Xing Chen et al.   PLoS One

The Triphenylethylenes, a Novel Class of Antifungals

(2014) A. R. Odom   mBio

Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo

(2014) A. Butts et al.   mBio

Expanding the use of alternative models to investigate novel aspects of immunity to microbial pathogens

(2014) Nuria Trevijano-Contador et al.   Virulence

Fungal Vaccines and Immunotherapeutics

(2014) E. Santos et al.   Cold Spring Harbor Perspectives in Medicine

Mechanisms of Antifungal Drug Resistance

(2014) Leah E. Cowen et al.   Cold Spring Harbor Perspectives in Medicine

Efflux pump proteins in antifungal resistance

(2014) Rajendra Prasad et al.   Frontiers in Pharmacology

Mechanism of Action of Efinaconazole, a Novel Triazole Antifungal Agent

(2013) Yoshiyuki Tatsumi et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Amphotericin B- and Voriconazole-Echinocandin Combinations against Aspergillus spp.: Effect of Serum on Inhibitory and Fungicidal Interactions

(2013) Antigoni Elefanti et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Properties and mechanisms of action of naturally occurring antifungal peptides

(2013) Nicole L. van der Weerden et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Human Monoclonal Antibody-Based Therapy in the Treatment of Invasive Candidiasis

(2013) Francesca Bugli et al.   Clinical & Developmental Immunology

Update on antifungal resistance in Aspergillus and Candida

(2013) M.C. Arendrup   CLINICAL MICROBIOLOGY AND INFECTION

Azole resistance in Aspergillus fumigatus

(2013) Edith Vermeulen et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Photodynamic inactivation of biofilm: taking a lightly colored approach to stubborn infection

(2013) Wanessa CMA de Melo et al.   Expert Review of Anti-Infective Therapy

Synergistic effect of doxycycline and fluconazole againstCandida albicansbiofilms and the impact of calcium channel blockers

(2013) Yuan Gao et al.   FEMS YEAST RESEARCH

Erg11mutations associated with azole resistance in clinical isolates ofCandida albicans

(2013) Ming-Jie Xiang et al.   FEMS YEAST RESEARCH

Combined antifungal approach for the treatment of invasive mucormycosis in patients with hematologic diseases: a report from the SEIFEM and FUNGISCOPE registries

(2013) L. Pagano et al.   HAEMATOLOGICA

The role of oxidative and nitrosative bursts caused by azoles and amphotericin B against the fungal pathogen Cryptococcus gattii

(2013) G. F. Ferreira et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Development of a Luminex-Based Multiplex Assay for Detection of Mutations Conferring Resistance to Echinocandins in Candida glabrata

(2013) C. D. Pham et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Environmental study of azole-resistantAspergillus fumigatuswith TR34/L98H mutations in thecyp51A gene in Iran

(2013) Hamid Badali et al.   MYCOSES

Antifungal Efficacy during Candida krusei Infection in Non-Conventional Models Correlates with the Yeast In Vitro Susceptibility Profile

(2013) Liliana Scorzoni et al.   PLoS One

Exopolymer Diversity and the Role of Levan in Bacillus subtilis Biofilms

(2013) Iztok Dogsa et al.   PLoS One

Antifungal agents commonly used in the superficial and mucosal candidiasis treatment: mode of action and resistance development

(2013) Małgorzata Bondaryk et al.   Postepy Dermatologii i Alergologii

Galleria mellonellaas a model host to studyParacoccidioides lutziiandHistoplasma capsulatum

(2013) Luciana Thomaz et al.   Virulence

Calcineurin Governs Thermotolerance and Virulence of Cryptococcus gattii

(2013) Ying-Lien Chen et al.   G3-Genes Genomes Genetics

Fitness Trade-offs Restrict the Evolution of Resistance to Amphotericin B

(2013) Benjamin Matteson Vincent et al.   PLOS BIOLOGY

Interactions between copy number and expression level of genes involved in fluconazole resistance in Candida glabrata

(2013) Salma Abbes et al.   Frontiers in Cellular and Infection Microbiology

An oral vaccine against candidiasis generated by a yeast molecular display system

(2013) Seiji Shibasaki et al.   Pathogens and Disease

Yeast ATP-Binding Cassette Transporters Conferring Multidrug Resistance

(2012) Rajendra Prasad et al.   Annual Review of Microbiology

Azole Resistance by Loss of Function of the Sterol Δ5,6-Desaturase Gene (ERG3) in Candida albicans Does Not Necessarily Decrease Virulence

(2012) L. A. Vale-Silva et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Adhesion of Histoplasma capsulatum to pneumocytes and biofilm formation on an abiotic surface

(2012) N.S. Pitangui et al.   BIOFOULING

In vitro activities of antifungal agents alone and in combination against fluconazole-susceptible and -resistant strains of Candida dubliniensis

(2012) Liliane Alves Scheid et al.   Brazilian Journal of Infectious Diseases

In vitro and in vivo role of heat shock protein 90 in Amphotericin B resistance of Aspergillus terreus

(2012) G. Blum et al.   CLINICAL MICROBIOLOGY AND INFECTION

Inhalable highly concentrated itraconazole nanosuspension for the treatment of bronchopulmonary aspergillosis

(2012) Chris Rundfeldt et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Amino acid substitutions in the Candida albicans sterol  5,6-desaturase (Erg3p) confer azole resistance: characterization of two novel mutants with impaired virulence

(2012) F. Morio et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Mechanisms of azole resistance in 52 clinical isolates of Candida tropicalis in China

(2012) C. Jiang et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Tacrolimus Enhances the Potency of Posaconazole Against Rhizopus oryzae In Vitro and in an Experimental Model of Mucormycosis

(2012) R. E. Lewis et al.   JOURNAL OF INFECTIOUS DISEASES

Fungal cell wall vaccines: an update

(2012) J. E. Edwards   JOURNAL OF MEDICAL MICROBIOLOGY

Clonal Expansion and Emergence of Environmental Multiple-Triazole-Resistant Aspergillus fumigatus Strains Carrying the TR34/L98H Mutations in the cyp51A Gene in India

(2012) Anuradha Chowdhary et al.   PLoS One

Medicinal plants extracts affect virulence factors expression and biofilm formation by the uropathogenic Escherichia coli

(2012) Dorota Wojnicz et al.   UROLOGICAL RESEARCH

Biofilm formation of Malassezia pachydermatis from dogs

(2012) Luciana A. Figueredo et al.   VETERINARY MICROBIOLOGY

Therapeutic DNA Vaccine Encoding Peptide P10 against Experimental Paracoccidioidomycosis

(2012) Glauce M. G. Rittner et al.   PLoS Neglected Tropical Diseases

A Candida Biofilm-Induced Pathway for Matrix Glucan Delivery: Implications for Drug Resistance

(2012) Heather T. Taff et al.   PLoS Pathogens

Innovative Strategies to Overcome Biofilm Resistance

(2012) Aleksandra Taraszkiewicz et al.   Biomed Research International

Vaccine and Immunotherapeutic Approaches for the Prevention of Cryptococcosis: Lessons Learned from Animal Models

(2012) Camaron R. Hole et al.   Frontiers in Microbiology

New Approaches in the Development of a Vaccine for Mucosal Candidiasis: Progress and Challenges

(2012) Anna Vecchiarelli et al.   Frontiers in Microbiology

It only takes one to do many jobs: Amphotericin B as antifungal and immunomodulatory drug

(2012) Ana C. Mesa-Arango et al.   Frontiers in Microbiology

In VitroInteraction between Fluconazole and Triclosan against Clinical Isolates of Fluconazole-Resistant Candida albicans Determined by Different Methods

(2011) Lu Yu et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Identification of a Cryptococcus neoformans Cytochrome P450 Lanosterol 14α-Demethylase (Erg11) Residue Critical for Differential Susceptibility between Fluconazole/Voriconazole and Itraconazole/Posaconazole

(2011) Edward Sionov et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Azole Resistance in Aspergillus fumigatus Isolates from the ARTEMIS Global Surveillance Study Is Primarily Due to the TR/L98H Mutation in thecyp51AGene

(2011) Shawn R. Lockhart et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Advances in synthetic approach to and antifungal activity of triazoles

(2011) Kumari Shalini et al.   Beilstein Journal of Organic Chemistry

Protective Immunity against Experimental Pulmonary Cryptococcosis in T Cell-Depleted Mice

(2011) Karen L. Wozniak et al.   Clinical and Vaccine Immunology

New Lead Structures in Antifungal Drug Discovery

(2011) Chunquan Sheng et al.   CURRENT MEDICINAL CHEMISTRY

C. elegans: model host and tool for antimicrobial drug discovery

(2011) J. J. Ewbank et al.   Disease Models & Mechanisms

A Flucytosine-Responsive Mbp1/Swi4-Like Protein, Mbs1, Plays Pleiotropic Roles in Antifungal Drug Resistance, Stress Response, and Virulence of Cryptococcus neoformans

(2011) Min-Hee Song et al.   EUKARYOTIC CELL

Live Imaging of Disseminated Candidiasis in Zebrafish Reveals Role of Phagocyte Oxidase in Limiting Filamentous Growth

(2011) Kimberly M. Brothers et al.   EUKARYOTIC CELL

Fusarium pathogenesis investigated using Galleria mellonella as a heterologous host

(2011) Jeffrey J. Coleman et al.   Fungal Biology

Immunization with Apoptotic Phagocytes Containing Histoplasma capsulatum Activates Functional CD8+T Cells To Protect against Histoplasmosis

(2011) Shih-Hung Hsieh et al.   INFECTION AND IMMUNITY

Combined use of Paracoccidioides brasiliensis recombinant rPb27 and rPb40 antigens in an enzyme-linked immunosorbent assay for immunodiagnosis of paracoccidioidomycosis

(2011) V.C. Fernandes et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Amphotericin B mediates killing in Cryptococcus neoformans through the induction of a strong oxidative burst

(2011) Fernanda Sangalli-Leite et al.   MICROBES AND INFECTION

Biofilm formation by zygomycetes: quantification, structure and matrix composition

(2011) R. Singh et al.   MICROBIOLOGY-SGM

Pathogenesis of Candida albicans Infections in the Alternative Chorio-Allantoic Membrane Chicken Embryo Model Resembles Systemic Murine Infections

(2011) Ilse D. Jacobsen et al.   PLoS One

Zebrafish embryos as an alternative to animal experiments—A commentary on the definition of the onset of protected life stages in animal welfare regulations

(2011) Uwe Strähle et al.   REPRODUCTIVE TOXICOLOGY

Methods for usingGalleria mellonellaas a model host to study fungal pathogenesis

(2011) Beth Burgwyn Fuchs et al.   Virulence

Persister Cells

(2010) Kim Lewis   Annual Review of Microbiology

Identification and Characterization of Four Azole-Resistant erg3 Mutants of Candida albicans

(2010) C. M. Martel et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Novel FKS Mutations Associated with Echinocandin Resistance in Candida Species

(2010) G. Garcia-Effron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Clinical Practice Guidelines for the Management of Cryptococcal Disease: 2010 Update by the Infectious Diseases Society of America

(2010) John R. Perfect et al.   CLINICAL INFECTIOUS DISEASES

Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature

(2010) Florent Morio et al.   DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE

Embryonated Eggs as an Alternative Infection Model To Investigate Aspergillus fumigatus Virulence

(2010) I. D. Jacobsen et al.   INFECTION AND IMMUNITY

Zebrafish as a Model Host for Candida albicans Infection

(2010) C. C. Chao et al.   INFECTION AND IMMUNITY

Genetic Basis ofCandidaBiofilm Resistance Due to Drug‐Sequestering Matrix Glucan

(2010) Jeniel E. Nett et al.   JOURNAL OF INFECTIOUS DISEASES

Role of filamentation in Galleria mellonella killing by Candida albicans

(2010) Beth Burgwyn Fuchs et al.   MICROBES AND INFECTION

Molecular Mechanisms of Resistance to 5-Fluorocytosine in Laboratory Mutants of Candida glabrata

(2010) Patrick Vandeputte et al.   MYCOPATHOLOGIA

Transcriptional response to fluconazole and amphotericin B in Candida albicans biofilms

(2010) Heleen Nailis et al.   RESEARCH IN MICROBIOLOGY

Candidemia em hospital terciário do nordeste do Brasil

(2010) Sylvia Lemos Hinrichsen et al.   Revista da Sociedade Brasileira de Medicina Tropical

The relevance of heat shock regulation in fungal pathogens of humans

(2010) Alistair J.P. Brown et al.   Virulence

Dispersion as an Important Step in the Candida albicans Biofilm Developmental Cycle

(2010) Priya Uppuluri et al.   PLoS Pathogens

Cryptococcus neoformans Overcomes Stress of Azole Drugs by Formation of Disomy in Specific Multiple Chromosomes

(2010) Edward Sionov et al.   PLoS Pathogens

Role for Fks1 in the Intrinsic Echinocandin Resistance of Fusarium solani as Evidenced by Hybrid Expression in Saccharomyces cerevisiae

(2009) S. K. Katiyar et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effect of Candida glabrata FKS1 and FKS2 Mutations on Echinocandin Sensitivity and Kinetics of 1,3- -D-Glucan Synthase: Implication for the Existing Susceptibility Breakpoint

(2009) G. Garcia-Effron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Efflux-Mediated Antifungal Drug Resistance

(2009) R. D. Cannon et al.   CLINICAL MICROBIOLOGY REVIEWS

Our Current Understanding of Fungal Biofilms

(2009) Gordon Ramage et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Amphotericin B and Its New Derivatives – Mode of Action

(2009) M. Baginski et al.   CURRENT DRUG METABOLISM

Novel Approaches to Control Biofilm Infections

(2009) Andreia Estrela et al.   CURRENT MEDICINAL CHEMISTRY

Candida albicansHyphal Formation and Virulence Assessed Using aCaenorhabditis elegansInfection Model

(2009) Read Pukkila-Worley et al.   EUKARYOTIC CELL

Antifungal drug resistance mechanisms in fungal pathogens from the perspective of transcriptional gene regulation

(2009) Dominique Sanglard et al.   FEMS YEAST RESEARCH

Time Course Global Gene Expression Analysis of an In VivoCandidaBiofilm

(2009) Jeniel E. Nett et al.   JOURNAL OF INFECTIOUS DISEASES

Histoplasma capsulatumandCaenorhabditis elegans: a simple nematode model for an innate immune response to fungal infection

(2009) Clayton H. Johnson et al.   MEDICAL MYCOLOGY

Presence of Extracellular DNA in the Candida albicans Biofilm Matrix and its Contribution to Biofilms

(2009) Margarida Martins et al.   MYCOPATHOLOGIA

Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

(2009) Ikechukwu Okoli et al.   PLoS One

Formación de biopelículas de Candida albicans en condiciones de flujo utilizando un aparato de Robbins modificado mejorado

(2009) Gordon Ramage et al.   REVISTA IBEROAMERICANA DE MICOLOGIA

Mutations in the fks1 Gene in Candida albicans, C. tropicalis, and C. krusei Correlate with Elevated Caspofungin MICs Uncovered in AM3 Medium Using the Method of the European Committee on Antibiotic Susceptibility Testing

(2008) M. Desnos-Ollivier et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Chemical Genomic Screen in Saccharomyces cerevisiae Reveals a Role for Diphthamidation of Translation Elongation Factor 2 in Inhibition of Protein Synthesis by Sordarin

(2008) J. Botet et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Abc1p Is a Multidrug Efflux Transporter That Tips the Balance in Favor of Innate Azole Resistance in Candida krusei

(2008) E. Lamping et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A Naturally Occurring Proline-to-Alanine Amino Acid Change in Fks1p in Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis Accounts for Reduced Echinocandin Susceptibility

(2008) G. Garcia-Effron et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

MFS transportome of the human pathogenic yeast Candida albicans

(2008) Manisha Gaur et al.   BMC GENOMICS

Treatment of Aspergillosis: Clinical Practice Guidelines of the Infectious Diseases Society of America

(2008) Thomas J. Walsh et al.   CLINICAL INFECTIOUS DISEASES

A Gain-of-Function Mutation in the Transcription Factor Upc2p Causes Upregulation of Ergosterol Biosynthesis Genes and Increased Fluconazole Resistance in a ClinicalCandida albicansIsolate

(2008) Nico Dunkel et al.   EUKARYOTIC CELL

Functional analysis of Candida albicans GPI-anchored proteins: Roles in cell wall integrity and caspofungin sensitivity

(2008) Armêl Plaine et al.   FUNGAL GENETICS AND BIOLOGY

Anti-biofilm properties of chitosan-coated surfaces

(2008) Ross P. Carlson et al.   JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION

Candida lusitaniaefungemia in cancer patients: risk factors for amphotericin B failure and outcome

(2008) Bradley J. Atkinson et al.   MEDICAL MYCOLOGY

The characteristics ofAspergillus fumigatusmycetoma development: is this a biofilm?

(2008) Eilidh Mowat et al.   MEDICAL MYCOLOGY

Additive effect of P10 immunization and chemotherapy in anergic mice challenged intratracheally with virulent yeasts of Paracoccidioides brasiliensis

(2008) Alexandre F. Marques et al.   MICROBES AND INFECTION

The expression of genes involved in the ergosterol biosynthesis pathway inCandida albicansandCandida dubliniensisbiofilms exposed to fluconazole

(2008) Silvia Borecká-Melkusová et al.   MYCOSES

Resistance to Antifungal Agents: Mechanisms and Clinical Impact

(2007) Z. A. Kanafani et al.   CLINICAL INFECTIOUS DISEASES