Whole animal HTS of small molecules for antifungal compounds

Candida parapsilosis Resistance to Fluconazole: Molecular Mechanisms andIn VivoImpact in Infected Galleria mellonella Larvae

(2015) Ana Carolina R. Souza et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes

(2015) Stuart L. Schreiber et al.   CELL

The discovery of novel antifungal scaffolds by structural simplification of the natural product sampangine

(2015) Zhigan Jiang et al.   CHEMICAL COMMUNICATIONS

Discovery of highly potent triazoleantifungal agents with piperidine-oxadiazole side chains

(2015) Xiaomeng He et al.   MedChemComm

Looking intoCandida albicansinfection, host response, and antifungal strategies

(2015) Yan Wang   Virulence

Mutation of G234 amino acid residue inCandida albicansdrug-resistance-related protein Rta2p is associated with fluconazole resistance and dihydrosphingosine transport

(2015) Shi-Qun Zhang et al.   Virulence

Caenorhabditis elegans: A Model System for Anti-Cancer Drug Discovery and Therapeutic Target Identification

(2014) Robert A. Kobet et al.   Biomolecules & Therapeutics

A Multi-Host Approach for the Systematic Analysis of Virulence Factors inCryptococcus neoformans

(2014) Athanasios Desalermos et al.   JOURNAL OF INFECTIOUS DISEASES

Multistate Point-Prevalence Survey of Health Care–Associated Infections

(2014) Shelley S. Magill et al.   NEW ENGLAND JOURNAL OF MEDICINE

Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus

(2014) Rajmohan Rajamuthiah et al.   PLoS One

Automated, high-throughput, motility analysis in Caenorhabditis elegans and parasitic nematodes: Applications in the search for new anthelmintics

(2014) Steven D. Buckingham et al.   International Journal for Parasitology-Drugs and Drug Resistance

Echinocandins in the treatment of candidaemia and invasive candidiasis: clinical and economic perspectives

(2013) Chin Fen Neoh et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Novel benzothiazole derivatives with a broad antifungal spectrum: design, synthesis and structure–activity relationships

(2013) Yang Liu et al.   MedChemComm

Caenorhabditis elegans-based Model Systems for Antifungal Drug Discovery

(2012) Cleo G. Anastassopoulou et al.   CURRENT PHARMACEUTICAL DESIGN

The role of mycelium production and a MAPK-mediated immune response in theC. elegans-Fusariummodel system

(2012) Maged Muhammed et al.   MEDICAL MYCOLOGY

An image analysis toolbox for high-throughput C. elegans assays

(2012) Carolina Wählby et al.   NATURE METHODS

An Efficient and Novel Screening Model for Assessing the Bioactivity of Extracts against Multidrug-ResistantPseudomonas aeruginosaUsingCaenorhabditis elegans

(2011) Yu-meng ZHOU et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

UsingCaenorhabditis elegansfor antimicrobial drug discovery

(2011) Athanasios Desalermos et al.   Expert Opinion on Drug Discovery

Antifungal Activity of Microbial Secondary Metabolites

(2011) Jeffrey J. Coleman et al.   PLoS One

Characterization of Plant-Derived Saponin Natural Products againstCandida albicans

(2010) Jeffrey J. Coleman et al.   ACS Chemical Biology

99th Dahlem Conference on Infection, Inflammation and Chronic Inflammatory Disorders: Caenorhabditis elegans as a model to study tissues involved in host immunity and microbial pathogenesis

(2010) J. E. Irazoqui et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Invasive Fungal Infections among Organ Transplant Recipients: Results of the Transplant‐Associated Infection Surveillance Network (TRANSNET)

(2010) Peter G. Pappas et al.   CLINICAL INFECTIOUS DISEASES

Invasive fungal infections in congenital immunodeficiencies

(2010) C. Antachopoulos   CLINICAL MICROBIOLOGY AND INFECTION

Epidemiology of Invasive Mycoses in North America

(2010) Michael A. Pfaller et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Natural products as antifungal agents against clinically relevant pathogens

(2010) Roberto Di Santo   NATURAL PRODUCT REPORTS

Know your chemical space

(2010) Andrew L Hopkins et al.   Nature Chemical Biology

An insight into the antifungal pipeline: selected new molecules and beyond

(2010) Luis Ostrosky-Zeichner et al.   NATURE REVIEWS DRUG DISCOVERY

From the outside in and the inside out: Antifungal immune responses inCaenorhabditis elegans

(2010) Read Pukkila-Worley et al.   Virulence

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

(2009) Terence I. Moy et al.   ACS Chemical Biology

Clinical Practice Guidelines for the Management of Candidiasis: 2009 Update by the Infectious Diseases Society of America

(2009) Peter G. Pappas et al.   CLINICAL INFECTIOUS DISEASES

Antifungal Drug Discovery through the Study of Invertebrate Model Hosts

(2009) R. Pukkila-Worley et al.   CURRENT MEDICINAL CHEMISTRY

Candida albicansHyphal Formation and Virulence Assessed Using aCaenorhabditis elegansInfection Model

(2009) Read Pukkila-Worley et al.   EUKARYOTIC CELL

Evolutionarily conserved recognition and innate immunity to fungal pathogens by the scavenger receptors SCARF1 and CD36

(2009) Terry K. Means et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A C. elegans-based, whole animal, in vivo screen for the identification of antifungal compounds

(2009) Emmanouil Tampakakis et al.   Nature Protocols

WormBase: a comprehensive resource for nematode research

(2009) Todd W. Harris et al.   NUCLEIC ACIDS RESEARCH

Identification of Antifungal Compounds Active against Candida albicans Using an Improved High-Throughput Caenorhabditis elegans Assay

(2009) Ikechukwu Okoli et al.   PLoS One

Efflux in Fungi: La Pièce de Résistance

(2009) Jeffrey J. Coleman et al.   PLoS Pathogens

Changing epidemiology of systemic fungal infections

(2008) M. Richardson et al.   CLINICAL MICROBIOLOGY AND INFECTION