Synthesis of Ru(ii)–benzene complexes containing aroylthiourea ligands, and their binding with biomolecules and in vitro cytotoxicity through apoptosis

Half-sandwich RuCl2(η6-p-cymene) core complexes containing sulfur donor aroylthiourea ligands: DNA and protein binding, DNA cleavage and cytotoxic studies

(2016) Kumaramangalam Jeyalakshmi et al.   DALTON TRANSACTIONS

Synthesis of Ni(II) complexes bearing indole-based thiosemicarbazone ligands for interaction with biomolecules and some biological applications

(2016) Jebiti Haribabu et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Ruthenium(II) p-cymene complexes of naphthoquinone derivatives as antitumor agents: A structure−activity relationship study

(2016) Leila Tabrizi et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Synthesis, X-ray crystal structure, DNA/protein binding and DNA cleavage studies of novel copper(ii) complexes of N-substituted isatin thiosemicarbazone ligands

(2016) Mathiyan Muralisankar et al.   NEW JOURNAL OF CHEMISTRY

In vitro anticancer activity of methyl caffeate isolated from Solanum torvum Swartz. fruit

(2015) C. Balachandran et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Structural modeling, in vitro antiproliferative activity, and the effect of substituents on the DNA fastening and scission actions of heteroleptic copper(ii) complexes with terpyridines and naproxen

(2015) Dharmasivam Mahendiran et al.   NEW JOURNAL OF CHEMISTRY

Strong in Vitro Cytotoxic Potential of New Ruthenium–Cymene Complexes

(2015) Stefan Nikolić et al.   ORGANOMETALLICS

Photocytotoxic luminescent lanthanide complexes of DTPA–bisamide using quinoline as photosensitizer

(2015) Khushbu Singh et al.   RSC Advances

Synthesis, DNA/protein binding, molecular docking, DNA cleavage and in vitro anticancer activity of nickel(ii) bis(thiosemicarbazone) complexes

(2015) Jebiti Haribabu et al.   RSC Advances

SHELXT– Integrated space-group and crystal-structure determination

(2015) George M. Sheldrick   Acta Crystallographica A-Foundation and Advances

A flavonoid isolated from Streptomyces sp. (ERINLG-4) induces apoptosis in human lung cancer A549 cells through p53 and cytochrome c release caspase dependant pathway

(2014) C. Balachandran et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Self-assembled Cu(ii) and Ni(ii) metallamacrocycles formed from 3,3,3′,3′-tetrabenzyl-1,1′-aroylbis(thiourea) ligands: DNA and protein binding studies, and cytotoxicity of trinuclear complexes

(2014) Nagamani Selvakumaran et al.   DALTON TRANSACTIONS

Arene–Ruthenium(II) Acylpyrazolonato Complexes: Apoptosis-Promoting Effects on Human Cancer Cells

(2014) Riccardo Pettinari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Organometallic ruthenium(II) scorpionate as topo IIα inhibitor; in vitro binding studies with DNA, HPLC analysis and its anticancer activity

(2014) Rais Ahmad Khan et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Synthesis, structure, DNA and protein binding studies, and cytotoxic activity of nickel(II) complexes containing 3,3-dialkyl/aryl-1-(2,4-dichlorobenzoyl)thiourea ligands

(2014) N. Selvakumaran et al.   POLYHEDRON

Biomedical and Biochemical Applications of Self-Assembled Metallacycles and Metallacages

(2013) Timothy R. Cook et al.   ACCOUNTS OF CHEMICAL RESEARCH

A silver complex of N,N′-disubstituted cyclic thiourea as an anti-inflammatory inhibitor of IκB kinase

(2013) Iris Wing-Shan Lin et al.   CHEMICAL COMMUNICATIONS

Exploration of the medical periodic table: towards new targets

(2013) Nicolas P. E. Barry et al.   CHEMICAL COMMUNICATIONS

The path for metal complexes to a DNA target

(2013) Alexis C. Komor et al.   CHEMICAL COMMUNICATIONS

Application of mass spectrometric techniques to delineate the modes-of-action of anticancer metallodrugs

(2013) Christian G. Hartinger et al.   CHEMICAL SOCIETY REVIEWS

New ruthenium(ii) arene complexes of anthracenyl-appended diazacycloalkanes: effect of ligand intercalation and hydrophobicity on DNA and protein binding and cleavage and cytotoxicity

(2013) Mani Ganeshpandian et al.   DALTON TRANSACTIONS

Transferrin Serves As a Mediator to Deliver Organometallic Ruthenium(II) Anticancer Complexes into Cells

(2013) Wei Guo et al.   INORGANIC CHEMISTRY

DNA/Protein Binding, Molecular Docking, and in Vitro Anticancer Activity of Some Thioether-Dipyrrinato Complexes

(2013) Rakesh Kumar Gupta et al.   INORGANIC CHEMISTRY

Anticancer Activity and DNA Binding of a Bifunctional Ru(II) Arene Aqua-Complex with the 2,4-Diamino-6-(2-pyridyl)-1,3,5-triazine Ligand

(2013) Natalia Busto et al.   INORGANIC CHEMISTRY

Enzyme inhibition by metal complexes: concepts, strategies and applications

(2013) Kelly J. Kilpin et al.   Chemical Science

Designing organometallic compounds for catalysis and therapy

(2012) Anna Louisa Noffke et al.   CHEMICAL COMMUNICATIONS

Targeted therapy vs. DNA-adduct formation-guided design: thoughts about the future of metal-based anticancer drugs

(2012) Gianni Sava et al.   DALTON TRANSACTIONS

Mixed ligand palladium(ii) complexes of 6-methoxy-2-oxo-1,2-dihydroquinoline-3-carbaldehyde 4N-substituted thiosemicarbazones with triphenylphosphine co-ligand: Synthesis, crystal structure and biological properties

(2012) Eswaran Ramachandran et al.   DALTON TRANSACTIONS

Challenges and Opportunities in the Development of Organometallic Anticancer Drugs

(2012) Christian G. Hartinger et al.   ORGANOMETALLICS

Nickel and cobalt complexes of benzoic acid (2-hydroxy-benzylidene)-hydrazide ligand: synthesis, structure and comparative in vitro evaluations of biological perspectives

(2012) Paramasivam Krishnamoorthy et al.   RSC Advances

From Conventional to Unusual Enzyme Inhibitor Scaffolds: The Quest for Target Specificity

(2011) Eric Meggers   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Agaritine from Agaricus blazei Murrill induces apoptosis in the leukemic cell line U937

(2011) Hidehiko Akiyama et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Maleimide-functionalised organoruthenium anticancer agents and their binding to thiol-containing biomolecules

(2011) Muhammad Hanif et al.   CHEMICAL COMMUNICATIONS

Metal-based antitumour drugs in the post-genomic era: what comes next?

(2011) Gianni Sava et al.   DALTON TRANSACTIONS

Targeted and multifunctional arene ruthenium chemotherapeutics

(2011) Gregory S. Smith et al.   DALTON TRANSACTIONS

Efficient Plasmid DNA Cleavage by Copper(II) Complexes of 1,4,7-Triazacyclononane Ligands Featuring Xylyl-Linked Guanidinium Groups

(2011) Linda Tjioe et al.   INORGANIC CHEMISTRY

Structure–activity relationship study of copper(II) complexes with 2-oxo-1,2-dihydroquinoline-3-carbaldehyde (4′-methylbenzoyl) hydrazone: synthesis, structures, DNA and protein interaction studies, antioxidative and cytotoxic activity

(2011) Duraisamy Senthil Raja et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Aggregation and DNA Intercalation Properties of Di(isocyano) Rhodium(I) Diimine Complexes

(2011) Larry Tso-Lun Lo et al.   ORGANOMETALLICS

Crystal structures, DNA-binding and cytotoxic activities studies of Cu(II) complexes with 2-oxo-quinoline-3-carbaldehyde Schiff-bases

(2010) Zeng-Chen Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Organometallic Anticancer Compounds

(2010) Gilles Gasser et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ruthenium(II) Complexes of Bipyridine−Glycoluril and their Interactions with DNA

(2009) Megha S. Deshpande et al.   BIOCONJUGATE CHEMISTRY

Synthesis, crystal structure, DNA interaction and antioxidant activities of two novel water-soluble Cu(2+) complexes derivated from 2-oxo-quinoline-3-carbaldehyde Schiff-bases

(2009) Zeng-Chen Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

OLEX2: a complete structure solution, refinement and analysis program

(2009) Oleg V. Dolomanov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Medicinal Organometallic Chemistry: Designing Metal Arene Complexes as Anticancer Agents

(2008) Anna F. A. Peacock et al.   Chemistry-An Asian Journal

DNA Structural Distortions Induced by Ruthenium−Arene Anticancer Compounds

(2008) Christian Gossens et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY