Pathogenesis of HIV-1 and Mycobacterium tuberculosis co-infection

The Influence of HIV on the Evolution of Mycobacterium tuberculosis

(2017) Anastasia S. Koch et al.   MOLECULAR BIOLOGY AND EVOLUTION

Novel role for IL-22 in protection during chronic Mycobacterium tuberculosis HN878 infection

(2017) P Treerat et al.   Mucosal Immunology

HIV persistence in tissue macrophages of humanized myeloid-only mice during antiretroviral therapy

(2017) Jenna B Honeycutt et al.   NATURE MEDICINE

Mycobacterial Dormancy Systems and Host Responses in Tuberculosis

(2017) Vidyullatha Peddireddy et al.   Frontiers in Immunology

DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

(2016) Laura Herrtwich et al.   CELL

Multiple Origins of Virus Persistence during Natural Control of HIV Infection

(2016) Eli A. Boritz et al.   CELL

Dissecting How CD4 T Cells Are Lost During HIV Infection

(2016) Gilad Doitsh et al.   Cell Host & Microbe

Th17 Cells Are Preferentially Infected Very Early after Vaginal Transmission of SIV in Macaques

(2016) Daniel J. Stieh et al.   Cell Host & Microbe

Macrophages sustain HIV replication in vivo independently of T cells

(2016) Jenna B. Honeycutt et al.   JOURNAL OF CLINICAL INVESTIGATION

Functional role of mucosal-associated invariant T cells in HIV infection

(2016) Alireza Saeidi et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Global burden of HIV, viral hepatitis, and tuberculosis in prisoners and detainees

(2016) Kate Dolan et al.   LANCET

Persistent HIV-1 replication maintains the tissue reservoir during therapy

(2016) Ramon Lorenzo-Redondo et al.   NATURE

Tumor-necrosis factor impairs CD4+ T cell–mediated immunological control in chronic viral infection

(2016) Marc Beyer et al.   NATURE IMMUNOLOGY

HIV-1 blocks the signaling adaptor MAVS to evade antiviral host defense after sensing of abortive HIV-1 RNA by the host helicase DDX3

(2016) Sonja I Gringhuis et al.   NATURE IMMUNOLOGY

ESX secretion systems: mycobacterial evolution to counter host immunity

(2016) Matthias I. Gröschel et al.   NATURE REVIEWS MICROBIOLOGY

A step forward understanding HIV-1 diversity

(2016) Redmond P. Smyth et al.   Retrovirology

Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection

(2016) Maximilian Muenchhoff et al.   Science Translational Medicine

TB biomarkers, TB correlates and human challenge models: New tools for improving assessment of new TB vaccines

(2016) Stefan H.E. Kaufmann et al.   TUBERCULOSIS

HIV Cell-to-Cell Spread Results in Earlier Onset of Viral Gene Expression by Multiple Infections per Cell

(2016) Mikaël Boullé et al.   PLoS Pathogens

In Vivo Molecular Dissection of the Effects of HIV-1 in Active Tuberculosis

(2016) Lucy C. K. Bell et al.   PLoS Pathogens

Dynamic Perturbations of the T-Cell Receptor Repertoire in Chronic HIV Infection and following Antiretroviral Therapy

(2016) James M. Heather et al.   Frontiers in Immunology

Immune Activation at Sites of HIV/TB Co-Infection Contributes to the Pathogenesis of HIV-1 Disease

(2016) Qinglai Meng et al.   PLoS One

Prevalence of tuberculosis in post-mortem studies of HIV-infected adults and children in resource-limited settings

(2015) Rishi K. Gupta et al.   AIDS

Healthy HIV-1-Infected Individuals on Highly Active Antiretroviral Therapy Harbor HIV-1 in Their Alveolar Macrophages

(2015) Sushma K. Cribbs et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

PQBP1 Is a Proximal Sensor of the cGAS-Dependent Innate Response to HIV-1

(2015) Sunnie M. Yoh et al.   CELL

The Cytosolic Sensor cGAS Detects Mycobacterium tuberculosis DNA to Induce Type I Interferons and Activate Autophagy

(2015) Robert O. Watson et al.   Cell Host & Microbe

Mycobacterium tuberculosis Differentially Activates cGAS- and Inflammasome-Dependent Intracellular Immune Responses through ESX-1

(2015) Ruth Wassermann et al.   Cell Host & Microbe

M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens

(2015) Mireia Coscolla et al.   Cell Host & Microbe

Paradoxical reactions and immune reconstitution inflammatory syndrome in tuberculosis

(2015) Lucy C.K. Bell et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

HIV-1 and interferons: who's interfering with whom?

(2015) Tomas Doyle et al.   NATURE REVIEWS MICROBIOLOGY

HIV reservoirs: what, where and how to target them

(2015) Melissa J. Churchill et al.   NATURE REVIEWS MICROBIOLOGY

HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling

(2015) Rachel P. J. Lai et al.   Nature Communications

Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells

(2015) Nicole L.K. Galloway et al.   Cell Reports

Latent and Active Tuberculosis Infection Increase Immune Activation in Individuals Co-Infected with HIV

(2015) Zuri A. Sullivan et al.   EBioMedicine

Short Communication: Circulating Plasma HIV-1 Viral Protein R in Dual HIV-1/Tuberculosis Infection

(2014) Zahra Toossi et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Macrophage Infection via Selective Capture of HIV-1-Infected CD4+ T Cells

(2014) Amy E. Baxter et al.   Cell Host & Microbe

Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells

(2014) Nina Calantone et al.   IMMUNITY

Genome-Wide Innate Immune Responses in HIV-1-Infected Macrophages Are Preserved Despite Attenuation of the NF- B Activation Pathway

(2014) M. Noursadeghi et al.   JOURNAL OF IMMUNOLOGY

Small alveolar macrophages are infected preferentially by HIV and exhibit impaired phagocytic function

(2014) K C Jambo et al.   Mucosal Immunology

Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk

(2014) Katrin D. Mayer-Barber et al.   NATURE

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

(2014) Netanya G. Sandler et al.   NATURE

In search of a new paradigm for protective immunity to TB

(2014) Cláudio Nunes-Alves et al.   NATURE REVIEWS MICROBIOLOGY

Association between HIV/AIDS and Multi-Drug Resistance Tuberculosis: A Systematic Review and Meta-Analysis

(2014) Yonatan Moges Mesfin et al.   PLoS One

Assessment of Mycobacterium tuberculosis transmission in Oxfordshire, UK, 2007–12, with whole pathogen genome sequences: an observational study

(2014) Timothy M Walker et al.   Lancet Respiratory Medicine

Modulation of the complement system in monocytes contributes to tuberculosis-associated immune reconstitution inflammatory syndrome

(2013) Huyen T.T. Tran et al.   AIDS

TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species

(2013) Francisco J. Roca et al.   CELL

The Effect of HIV-Related Immunosuppression on the Risk of Tuberculosis Transmission to Household Contacts

(2013) C.-C. Huang et al.   CLINICAL INFECTIOUS DISEASES

Tissue-Resident Macrophages Self-Maintain Locally throughout Adult Life with Minimal Contribution from Circulating Monocytes

(2013) Daigo Hashimoto et al.   IMMUNITY

HIV-1 Infection of Macrophages Dysregulates Innate Immune Responses to Mycobacterium tuberculosis by Inhibition of Interleukin-10

(2013) Gillian S. Tomlinson et al.   JOURNAL OF INFECTIOUS DISEASES

Systemic Immune Activation and Microbial Translocation in Dual HIV/Tuberculosis-Infected Subjects

(2013) Zahra Toossi et al.   JOURNAL OF INFECTIOUS DISEASES

HIV-1 evades innate immune recognition through specific cofactor recruitment

(2013) Jane Rasaiyaah et al.   NATURE

HIV-1 causes CD4 cell death through DNA-dependent protein kinase during viral integration

(2013) Arik Cooper et al.   NATURE

Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids

(2013) C. J. Cambier et al.   NATURE

Cell death by pyroptosis drives CD4 T-cell depletion in HIV-1 infection

(2013) Gilad Doitsh et al.   NATURE

PNAS Plus: From the Cover: IFI16 senses DNA forms of the lentiviral replication cycle and controls HIV-1 replication

(2013) M. R. Jakobsen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HIV-1 transcription and latency: an update

(2013) Carine Van Lint et al.   Retrovirology

IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV

(2013) K. M. Monroe et al.   SCIENCE

Cyclic GMP-AMP Synthase Is an Innate Immune Sensor of HIV and Other Retroviruses

(2013) D. Gao et al.   SCIENCE

Increased mortality associated with treated active tuberculosis in HIV-infected adults in Tanzania

(2013) Conrad Kabali et al.   TUBERCULOSIS

HIV Infection Disrupts the Sympatric Host–Pathogen Relationship in Human Tuberculosis

(2013) Lukas Fenner et al.   PLoS Genetics

Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases

(2012) Naomi F. Walker et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Early and nonreversible decrease of CD161++/MAIT cells in HIV infection

(2012) C. Cosgrove et al.   BLOOD

Mycobacterium Tuberculosis Activates the DNA-Dependent Cytosolic Surveillance Pathway within Macrophages

(2012) Paolo S. Manzanillo et al.   Cell Host & Microbe

Meta-Analysis: The Association Between HIV Infection and Extrapulmonary Tuberculosis

(2012) Cho Naing et al.   LUNG

A role for mucosal IL-22 production and Th22 cells in HIV-associated mucosal immunopathogenesis

(2012) C J Kim et al.   Mucosal Immunology

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

(2012) Hichem Lahouassa et al.   NATURE IMMUNOLOGY

Genomic HIV RNA Induces Innate Immune Responses through RIG-I-Dependent Sensing of Secondary-Structured RNA

(2012) Randi K. Berg et al.   PLoS One

Tuberculosis Incidence Rates during 8 Years of Follow-Up of an Antiretroviral Treatment Cohort in South Africa: Comparison with Rates in the Community

(2012) Ankur Gupta et al.   PLoS One

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

Regulation of Mycobacterium tuberculosis-Dependent HIV-1 Transcription Reveals a New Role for NFAT5 in the Toll-Like Receptor Pathway

(2012) Shahin Ranjbar et al.   PLoS Pathogens

Vitamin D Inhibits Human Immunodeficiency Virus Type 1 and Mycobacterium tuberculosis Infection in Macrophages through the Induction of Autophagy

(2012) Grant R. Campbell et al.   PLoS Pathogens

Phagosomal Rupture by Mycobacterium tuberculosis Results in Toxicity and Host Cell Death

(2012) Roxane Simeone et al.   PLoS Pathogens

TLR2-induced cytokine responses may characterize HIV-infected patients experiencing mycobacterial immune restoration disease

(2011) Dino B.A. Tan et al.   AIDS

Innate Immune Recognition ofMycobacterium tuberculosis

(2011) Johanneke Kleinnijenhuis et al.   Clinical & Developmental Immunology

MMP-1 drives immunopathology in human tuberculosis and transgenic mice

(2011) Paul Elkington et al.   JOURNAL OF CLINICAL INVESTIGATION

Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection

(2011) Bisweswar Nandi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa

(2011) A. R. Martineau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

(2011) S. J. Jenkins et al.   SCIENCE

Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors

(2011) Clare Jolly   VIROLOGY

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

MyD88-dependent TLR4 signaling is selectively impaired in alveolar macrophages from asymptomatic HIV+ persons

(2010) S. D. Tachado et al.   BLOOD

Inhibition of phagocytosis in HIV-1-infected macrophages relies on Nef-dependent alteration of focal delivery of recycling compartments

(2010) J. Mazzolini et al.   BLOOD

Mycobacterium tuberculosis protein ESAT-6 is a potent activator of the NLRP3/ASC inflammasome

(2010) Bibhuti B. Mishra et al.   CELLULAR MICROBIOLOGY

HIV Infection–Associated Tuberculosis: The Epidemiology and the Response

(2010) Haileyesus Getahun et al.   CLINICAL INFECTIOUS DISEASES

Effects of In Vitro HIV-1 Infection on Mycobacterial Growth in Peripheral Blood Monocyte-Derived Macrophages

(2010) S. Pathak et al.   INFECTION AND IMMUNITY

Exogenous Nef Is an Inhibitor ofMycobacterium tuberculosis-induced Tumor Necrosis Factor-α Production and Macrophage Apoptosis

(2010) Kuldeep Kumawat et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathological role of interleukin 17 in mice subjected to repeated BCG vaccination after infection withMycobacterium tuberculosis

(2010) Andrea Cruz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Preferential infection and depletion ofMycobacterium tuberculosis–specific CD4 T cells after HIV-1 infection

(2010) Christof Geldmacher et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immune reconstitution inflammatory syndrome in patients starting antiretroviral therapy for HIV infection: a systematic review and meta-analysis

(2010) Monika Müller et al.   LANCET INFECTIOUS DISEASES

An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis

(2010) Matthew P. R. Berry et al.   NATURE

Human T cell epitopes of Mycobacterium tuberculosis are evolutionarily hyperconserved

(2010) Iñaki Comas et al.   NATURE GENETICS

Revisiting Immune Exhaustion During HIV Infection

(2010) Alka Khaitan et al.   Current HIV/AIDS Reports

HIV-1 infection of macrophages is dependent on evasion of innate immune cellular activation

(2009) Jhen Tsang et al.   AIDS

HIV-1 Infection Impairs the Bronchoalveolar T-Cell Response to Mycobacteria

(2009) Barbara Kalsdorf et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

The Role of the Granuloma in Expansion and Dissemination of Early Tuberculous Infection

(2009) J. Muse Davis et al.   CELL

Antiretroviral Therapy for Control of the HIV-associated Tuberculosis Epidemic in Resource-Limited Settings

(2009) Stephen D. Lawn et al.   CLINICS IN CHEST MEDICINE

Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages

(2009) George B. Kyei et al.   JOURNAL OF CELL BIOLOGY

Impaired M. tuberculosis -mediated apoptosis in alveolar macrophages from HIV+ persons: potential role of IL-10 and BCL-3

(2009) Naimish R. Patel et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Induction of a Striking Systemic Cytokine Cascade prior to Peak Viremia in Acute Human Immunodeficiency Virus Type 1 Infection, in Contrast to More Modest and Delayed Responses in Acute Hepatitis B and C Virus Infections

(2009) A. R. Stacey et al.   JOURNAL OF VIROLOGY

Tuberculous Granuloma Induction via Interaction of a Bacterial Secreted Protein with Host Epithelium

(2009) H. E. Volkman et al.   SCIENCE

MafB/c-Maf Deficiency Enables Self-Renewal of Differentiated Functional Macrophages

(2009) A. Aziz et al.   SCIENCE

Gene expression in HIV-1/Mycobacterium tuberculosis co-infected macrophages is dominated by M. tuberculosis

(2009) Susan Maddocks et al.   TUBERCULOSIS

Emerging Concepts in the Immunopathogenesis of AIDS

(2008) Daniel C. Douek et al.   Annual Review of Medicine

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

The genetic heterogeneity of mendelian susceptibility to mycobacterial diseases

(2008) Saleh Al-Muhsen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Constitutive Activation of Phosphatidylinositol 3-Kinase Signaling Pathway Down-regulates TLR4-mediated Tumor Necrosis Factor-α Release in Alveolar Macrophages from Asymptomatic HIV-positive Personsin Vitro

(2008) Souvenir D. Tachado et al.   JOURNAL OF BIOLOGICAL CHEMISTRY