标题
Host-directed therapies for bacterial and viral infections
作者
关键词
-
出版物
NATURE REVIEWS DRUG DISCOVERY
Volume 17, Issue 1, Pages 35-56
出版商
Springer Nature
发表日期
2017-09-22
DOI
10.1038/nrd.2017.162
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Cell-Mediated Immunity to Target the Persistent Human Immunodeficiency Virus Reservoir
- (2017) James L. Riley et al. JOURNAL OF INFECTIOUS DISEASES
- Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial
- (2017) Meike H van der Ree et al. LANCET
- Tuberculosis reactivation in a patient receiving anti-programmed death-1 (PD-1) inhibitor for relapsed Hodgkin’s lymphoma
- (2016) Joycelyn J. X. Lee et al. ACTA ONCOLOGICA
- Sharpening nature's tools for efficient tuberculosis control: A review of the potential role and development of host-directed therapies and strategies for targeted respiratory delivery
- (2016) Gemma O'Connor et al. ADVANCED DRUG DELIVERY REVIEWS
- Approved Antiviral Drugs over the Past 50 Years
- (2016) Erik De Clercq et al. CLINICAL MICROBIOLOGY REVIEWS
- Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome
- (2016) Bita Shakoory et al. CRITICAL CARE MEDICINE
- Combination of Tenofovir Disoproxil Fumarate and Peginterferon α-2a Increases Loss of Hepatitis B Surface Antigen in Patients With Chronic Hepatitis B
- (2016) Patrick Marcellin et al. GASTROENTEROLOGY
- Statin adjunctive therapy shortens the duration of TB treatment in mice
- (2016) Noton K. Dutta et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Progress toward active or passive HIV-1 vaccination
- (2016) Amelia Escolano et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Restoration of T cell function in chronic hepatitis B patients upon treatment with interferon based combination therapy
- (2016) Annikki de Niet et al. JOURNAL OF HEPATOLOGY
- First-in-human application of the novel hepatitis B and hepatitis D virus entry inhibitor myrcludex B
- (2016) Antje Blank et al. JOURNAL OF HEPATOLOGY
- Aiming for cure in HBV and HDV infection
- (2016) Jörg Petersen et al. JOURNAL OF HEPATOLOGY
- Treatment of chronic hepatitis D with the entry inhibitor myrcludex B: First results of a phase Ib/IIa study
- (2016) Pavel Bogomolov et al. JOURNAL OF HEPATOLOGY
- Tuberculosis—advances in development of new drugs, treatment regimens, host-directed therapies, and biomarkers
- (2016) Robert S Wallis et al. LANCET INFECTIOUS DISEASES
- Inflammatory signaling in human tuberculosis granulomas is spatially organized
- (2016) Mohlopheni J Marakalala et al. NATURE MEDICINE
- Stimulating the RIG-I pathway to kill cells in the latent HIV reservoir following viral reactivation
- (2016) Peilin Li et al. NATURE MEDICINE
- The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
- (2016) Danny N. Khalil et al. Nature Reviews Clinical Oncology
- Hepatitis delta virus: insights into a peculiar pathogen and novel treatment options
- (2016) Florian A. Lempp et al. Nature Reviews Gastroenterology & Hepatology
- The effect of statins on influenza-like illness morbidity and mortality
- (2016) Paul Brassard et al. PHARMACOEPIDEMIOLOGY AND DRUG SAFETY
- Circulating Angiogenic Factors as Biomarkers of Disease Severity and Bacterial Burden in Pulmonary Tuberculosis
- (2016) Nathella Pavan Kumar et al. PLoS One
- Statin treatment is associated with a decreased risk of active tuberculosis: an analysis of a nationally representative cohort
- (2016) Chih-Cheng Lai et al. THORAX
- Antimicrobial Resistance in Mycobacterium tuberculosis : The Odd One Out
- (2016) Vegard Eldholm et al. TRENDS IN MICROBIOLOGY
- Which therapeutic strategy will achieve a cure for HIV-1?
- (2016) Anthony R Cillo et al. Current Opinion in Virology
- Dengue Virus Nonstructural Protein 1 Induces Vascular Leakage through Macrophage Migration Inhibitory Factor and Autophagy
- (2016) Hong-Ru Chen et al. PLoS Neglected Tropical Diseases
- CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease
- (2016) Shunsuke Sakai et al. PLoS Pathogens
- TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection
- (2016) Pushpa Jayaraman et al. PLoS Pathogens
- Dengue Virus NS1 Disrupts the Endothelial Glycocalyx, Leading to Hyperpermeability
- (2016) Henry Puerta-Guardo et al. PLoS Pathogens
- Pharmacologic Inhibition of Host Phosphodiesterase-4 Improves Isoniazid-Mediated Clearance of Mycobacterium tuberculosis
- (2016) Selvakumar Subbian et al. Frontiers in Immunology
- Phosphodiesterase inhibitors as adjunctive therapies for tuberculosis
- (2016) Bintou Ahmadou Ahidjo et al. EBioMedicine
- Adjunctive Phosphodiesterase-4 Inhibitor Therapy Improves Antibiotic Response to Pulmonary Tuberculosis in a Rabbit Model
- (2016) Selvakumar Subbian et al. EBioMedicine
- Tuberculosis Therapy Modifies the Cytokine Profile, Maturation State, and Expression of Inhibitory Molecules on Mycobacterium tuberculosis-Specific CD4+ T-Cells
- (2016) Kapil K. Saharia et al. PLoS One
- Mycobacterium tuberculosis exploits the formation of new blood vessels for its dissemination
- (2016) Helena Polena et al. Scientific Reports
- High-dose vitamin D3 in adults with pulmonary tuberculosis: a double-blind randomized controlled trial
- (2015) Nestan Tukvadze et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Preclinical and Clinical Evidence of Mycobacterium tuberculosis Persistence in the Hypoxic Niche of Bone Marrow Mesenchymal Stem Cells after Therapy
- (2015) Jaishree Garhyan et al. AMERICAN JOURNAL OF PATHOLOGY
- LAG3 Expression in Active Mycobacterium tuberculosis Infections
- (2015) Bonnie L. Phillips et al. AMERICAN JOURNAL OF PATHOLOGY
- Tuberculosis and other opportunistic infections in tofacitinib-treated patients with rheumatoid arthritis
- (2015) K L Winthrop et al. ANNALS OF THE RHEUMATIC DISEASES
- The role of immunophilins in viral infection
- (2015) Sam Hopkins et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis
- (2015) S. M. Irwin et al. Disease Models & Mechanisms
- Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis
- (2015) J.-P. Lanoix et al. Disease Models & Mechanisms
- AASLD guidelines for treatment of chronic hepatitis B
- (2015) Norah A. Terrault et al. HEPATOLOGY
- Heterogeneity in tuberculosis pathology, microenvironments and therapeutic responses
- (2015) Anne Lenaerts et al. IMMUNOLOGICAL REVIEWS
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- (2015) Xiao-wei Zheng et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- Nonclinical Models for Antituberculosis Drug Development: A Landscape Analysis
- (2015) Tawanda Gumbo et al. JOURNAL OF INFECTIOUS DISEASES
- Adjunctive vitamin D for treatment of active tuberculosis in India: a randomised, double-blind, placebo-controlled trial
- (2015) Peter Daley et al. LANCET INFECTIOUS DISEASES
- Broad CTL response is required to clear latent HIV-1 due to dominance of escape mutations
- (2015) Kai Deng et al. NATURE
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- (2015) Andreas Wack et al. NATURE IMMUNOLOGY
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- (2015) Tomas Doyle et al. NATURE REVIEWS MICROBIOLOGY
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- (2015) Guido V. Bloemberg et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2015) Stefany Moreno-Gamez et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Meenal Datta et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Naphak Modhiran et al. Science Translational Medicine
- Tim-3 blocking rescue macrophage and T cell function against Mycobacterium tuberculosis infection in HIV+ patients
- (2015) Isabel Sada-Ovalle et al. Journal of the International AIDS Society
- Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D₃
- (2015) Anna K. Coussens et al. PLoS Pathogens
- Efficacy of Adjunctive Tofacitinib Therapy in Mouse Models of Tuberculosis
- (2015) Mamoudou Maiga et al. EBioMedicine
- Statin Treatment and Mortality: Propensity Score-Matched Analyses of 2007-2008 and 2009-2010 Laboratory-Confirmed Influenza Hospitalizations
- (2015) M. R. Laidler et al. Open Forum Infectious Diseases
- Pulmonary embolism and reactivation of tuberculosis during everolimus therapy in a kidney transplant recipient
- (2015) Jolanta Barbara Fijałkowska-Morawska et al. Annals of Transplantation
- Gender-Dependent Differences in Plasma Matrix Metalloproteinase-8 Elevated in Pulmonary Tuberculosis
- (2015) Tarangini Sathyamoorthy et al. PLoS One
- PD-1, PD-L1 and PD-L2 Gene Expression on T-Cells and Natural Killer Cells Declines in Conjunction with a Reduction in PD-1 Protein during the Intensive Phase of Tuberculosis Treatment
- (2015) Syeda S. Hassan et al. PLoS One
- Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial
- (2015) Akhirunnesa Mily et al. PLoS One
- Bone Marrow Mesenchymal Stem Cells Provide an Antibiotic-Protective Niche for Persistent Viable Mycobacterium tuberculosis that Survive Antibiotic Treatment
- (2014) Gillian Beamer et al. AMERICAN JOURNAL OF PATHOLOGY
- Tuberculosis, Pulmonary Cavitation, and Matrix Metalloproteinases
- (2014) Catherine W. M. Ong et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Lung-Residing Myeloid-derived Suppressors Display Dual Functionality in Murine Pulmonary Tuberculosis
- (2014) Julia K. Knaul et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Statins Increase Rifampin Mycobactericidal Effect
- (2014) Lívia Silva Lobato et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Verapamil Increases the Bactericidal Activity of Bedaquiline against Mycobacterium tuberculosis in a Mouse Model
- (2014) Shashank Gupta et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Long-term safety and efficacy of microRNA-targeted therapy in chronic hepatitis C patients
- (2014) Meike H. van der Ree et al. ANTIVIRAL RESEARCH
- Interferon-gamma as adjunctive immunotherapy for invasive fungal infections: a case series
- (2014) Corine E Delsing et al. BMC INFECTIOUS DISEASES
- Interferon Lambda Alleles Predict Innate Antiviral Immune Responses and Hepatitis C Virus Permissiveness
- (2014) Timothy Sheahan et al. Cell Host & Microbe
- Analysis of Th1, Th17 and regulatory T cells in tuberculosis case contacts
- (2014) R.E. García Jacobo et al. CELLULAR IMMUNOLOGY
- Functional drug screening reveals anticonvulsants as enhancers of mTOR-independent autophagic killing of Mycobacterium tuberculosis through inositol depletion
- (2014) M. Schiebler et al. EMBO Molecular Medicine
- The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers
- (2014) Bruce E. Miller et al. EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS
- Unanticipated Mycobacterium tuberculosis complex culture inhibition by immune modulators, immune suppressants, a growth enhancer, and vitamins A and D: clinical implications
- (2014) Robert J. Greenstein et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- A randomized phase 2b study of peginterferon lambda-1a for the treatment of chronic HCV infection
- (2014) Andrew J. Muir et al. JOURNAL OF HEPATOLOGY
- Role of a 48-week pegylated interferon therapy in hepatitis B e antigen positive HIV-co-infected patients on cART including tenofovir: EMVIPEG study
- (2014) Patrick Miailhes et al. JOURNAL OF HEPATOLOGY
- Programmed Death (PD)-1:PD-Ligand 1/PD-Ligand 2 Pathway Inhibits T Cell Effector Functions during Human Tuberculosis
- (2014) J. O. Jurado et al. JOURNAL OF IMMUNOLOGY
- All-Trans Retinoic Acid-Triggered Antimicrobial Activity against Mycobacterium tuberculosis Is Dependent on NPC2
- (2014) M. Wheelwright et al. JOURNAL OF IMMUNOLOGY
- Inflammation and tuberculosis: host-directed therapies
- (2014) A. Zumla et al. JOURNAL OF INTERNAL MEDICINE
- Mycobacterium tuberculosisdysregulates MMP/TIMP balance to drive rapid cavitation and unrestrained bacterial proliferation
- (2014) André Kübler et al. JOURNAL OF PATHOLOGY
- Alteration of serum inflammatory cytokines in active pulmonary tuberculosis following anti-tuberculosis drug therapy
- (2014) Imran Hussain Chowdhury et al. MOLECULAR IMMUNOLOGY
- Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
- (2014) Katrin D. Mayer-Barber et al. NATURE
- Reprogramming human endothelial cells to haematopoietic cells requires vascular induction
- (2014) Vladislav M. Sandler et al. NATURE
- Interception of host angiogenic signalling limits mycobacterial growth
- (2014) Stefan H. Oehlers et al. NATURE
- Parallels between Cancer and Infectious Disease
- (2014) Richard S. Hotchkiss et al. NEW ENGLAND JOURNAL OF MEDICINE
- Metformin as adjunct antituberculosis therapy
- (2014) A. Singhal et al. Science Translational Medicine
- Tumor necrosis factor alpha in mycobacterial infection
- (2014) Anca Dorhoi et al. SEMINARS IN IMMUNOLOGY
- Perspectives on host adaptation in response to Mycobacterium tuberculosis: Modulation of inflammation
- (2014) Anca Dorhoi et al. SEMINARS IN IMMUNOLOGY
- Programmed death-1 receptor suppresses γ-IFN producing NKT cells in human tuberculosis
- (2014) Amar Singh et al. TUBERCULOSIS
- Manipulation of the Mononuclear Phagocyte System by Mycobacterium tuberculosis
- (2014) G. Lugo-Villarino et al. Cold Spring Harbor Perspectives in Medicine
- Novel Vaccination Strategies against Tuberculosis
- (2014) P. Andersen et al. Cold Spring Harbor Perspectives in Medicine
- Identification of Host-Targeted Small Molecules That Restrict Intracellular Mycobacterium tuberculosis Growth
- (2014) Sarah A. Stanley et al. PLoS Pathogens
- Allele-Specific Induction of IL-1β Expression by C/EBPβ and PU.1 Contributes to Increased Tuberculosis Susceptibility
- (2014) Guoliang Zhang et al. PLoS Pathogens
- Decreases in Colonic and Systemic Inflammation in Chronic HIV Infection after IL-7 Administration
- (2014) Irini Sereti et al. PLoS Pathogens
- Treatment of Progressive Multifocal Leukoencephalopathy With Interleukin 7
- (2014) Karl B. Alstadhaug et al. JAMA Neurology
- Autologous mesenchymal stromal cell infusion as adjunct treatment in patients with multidrug and extensively drug-resistant tuberculosis: an open-label phase 1 safety trial
- (2014) Aliaksandr Skrahin et al. Lancet Respiratory Medicine
- Reverse Translation in Tuberculosis: Neutrophils Provide Clues for Understanding Development of Active Disease
- (2014) Anca Dorhoi et al. Frontiers in Immunology
- Corticosteroid Effects on Sputum Culture in Pulmonary Tuberculosis: A Meta-Regression Analysis
- (2014) R. S. Wallis Open Forum Infectious Diseases
- Dengue pathogenesis: a disease driven by the host response
- (2014) Byron E.E. Martina SCIENCE PROGRESS
- Acceleration of Tuberculosis Treatment by Adjunctive Therapy with Verapamil as an Efflux Inhibitor
- (2013) Shashank Gupta et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Vitamin D accelerates clinical recovery from tuberculosis: results of the SUCCINCT Study [Supplementary Cholecalciferol in recovery from tuberculosis]. A randomized, placebo-controlled, clinical trial of vitamin D supplementation in patients with pulmonary tuberculosis’
- (2013) Nawal Salahuddin et al. BMC INFECTIOUS DISEASES
- TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species
- (2013) Francisco J. Roca et al. CELL
- Hepatitis B and D Viruses Exploit Sodium Taurocholate Co-transporting Polypeptide for Species-Specific Entry into Hepatocytes
- (2013) Yi Ni et al. GASTROENTEROLOGY
- Statin Therapy Reduces the Mycobacterium tuberculosis Burden in Human Macrophages and in Mice by Enhancing Autophagy and Phagosome Maturation
- (2013) Suraj P. Parihar et al. JOURNAL OF INFECTIOUS DISEASES
- Ibuprofen Therapy Resulted in Significantly Decreased Tissue Bacillary Loads and Increased Survival in a New Murine Experimental Model of Active Tuberculosis
- (2013) Cristina Vilaplana et al. JOURNAL OF INFECTIOUS DISEASES
- Adjuvant Host-Directed Therapy with Types 3 and 5 but Not Type 4 Phosphodiesterase Inhibitors Shortens the Duration of Tuberculosis Treatment
- (2013) Mamoudou Maiga et al. JOURNAL OF INFECTIOUS DISEASES
- Inhibiting the Programmed Death 1 Pathway Rescues Mycobacterium tuberculosis–Specific Interferon γ–Producing T Cells From Apoptosis in Patients With Pulmonary Tuberculosis
- (2013) Amar Singh et al. JOURNAL OF INFECTIOUS DISEASES
- Corticosteroids for prevention of mortality in people with tuberculosis: a systematic review and meta-analysis
- (2013) Julia A Critchley et al. LANCET INFECTIOUS DISEASES
- Immunosuppression in sepsis: a novel understanding of the disorder and a new therapeutic approach
- (2013) Richard S Hotchkiss et al. LANCET INFECTIOUS DISEASES
- The TLR4 antagonist Eritoran protects mice from lethal influenza infection
- (2013) Kari Ann Shirey et al. NATURE
- Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1)
- (2013) M. J. Fuller et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stem-Cell-Based Gene Therapy for HIV Infection
- (2013) Anjie Zhen et al. Viruses-Basel
- Antitubercular specific activity of ibuprofen and the other 2-arylpropanoic acids using the HT-SPOTi whole-cell phenotypic assay
- (2013) Juan D Guzman et al. BMJ Open
- HIV entry: a game of hide-and-fuse?
- (2013) Gregory B Melikyan Current Opinion in Virology
- Corticosteroids for Dengue – Why Don't They Work?
- (2013) Thi Hanh Tien Nguyen et al. PLoS Neglected Tropical Diseases
- Doxycycline and HIV Infection Suppress Tuberculosis-induced Matrix Metalloproteinases
- (2012) Naomi F. Walker et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- ESX-1 dependent impairment of autophagic flux byMycobacterium tuberculosisin human dendritic cells
- (2012) Alessandra Romagnoli et al. Autophagy
- Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections
- (2012) David M. Tobin et al. CELL
- Effects of Short-Course Oral Corticosteroid Therapy in Early Dengue Infection in Vietnamese Patients: A Randomized, Placebo-Controlled Trial
- (2012) D. T. H. Tam et al. CLINICAL INFECTIOUS DISEASES
- Potential efficacy of imiquimod on immunity-related cytokines in murine skin in vivo and in human Langerhans cells in vitro
- (2012) Xu Miao et al. INTERNATIONAL JOURNAL OF DERMATOLOGY
- Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver
- (2012) Shu-hao Hsu et al. JOURNAL OF CLINICAL INVESTIGATION
- MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
- (2012) Wei-Chih Tsai et al. JOURNAL OF CLINICAL INVESTIGATION
- Active Tuberculosis During Temsirolimus and Bevacizumab Treatment
- (2012) Chia-Chi Lin et al. JOURNAL OF CLINICAL ONCOLOGY
- The cyclophilin inhibitor SCY-635 suppresses viral replication and induces endogenous interferons in patients with chronic HCV genotype 1 infection
- (2012) Sam Hopkins et al. JOURNAL OF HEPATOLOGY
- The Tim3-Galectin 9 Pathway Induces Antibacterial Activity in Human Macrophages Infected with Mycobacterium tuberculosis
- (2012) I. Sada-Ovalle et al. JOURNAL OF IMMUNOLOGY
- Abelson Tyrosine Kinase Controls Phagosomal Acidification Required for Killing of Mycobacterium tuberculosis in Human Macrophages
- (2012) H. Bruns et al. JOURNAL OF IMMUNOLOGY
- IL-7 Restores Lymphocyte Functions in Septic Patients
- (2012) F. Venet et al. JOURNAL OF IMMUNOLOGY
- Risk of Tuberculosis Reactivation With Tofacitinib (CP-690550)
- (2012) Mamoudou Maiga et al. JOURNAL OF INFECTIOUS DISEASES
- Vitamins A & D Inhibit the Growth of Mycobacteria in Radiometric Culture
- (2012) Robert J. Greenstein et al. PLoS One
- PD-1 Blockage Reverses Immune Dysfunction and Hepatitis B Viral Persistence in a Mouse Animal Model
- (2012) Horng-Tay Tzeng et al. PLoS One
- A Comprehensive Review of Everolimus Clinical Reports
- (2012) Cheryle Gurk-Turner et al. TRANSPLANTATION
- Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus
- (2012) Huan Yan et al. eLife
- Assessment of Serum IL-1, IL-2 and IFN-γ Levels in Untreated Pulmonary Tuberculosis Patients: Role in Pathogenesis
- (2011) Muralidhar K. Katti ARCHIVES OF MEDICAL RESEARCH
- Imatinib-Sensitive Tyrosine Kinases Regulate Mycobacterial Pathogenesis and Represent Therapeutic Targets against Tuberculosis
- (2011) Ruth J. Napier et al. Cell Host & Microbe
- Effects of Mycobacterium tuberculosis ESAT-6/CFP-10 Fusion Protein on the Autophagy Function of Mouse Macrophages
- (2011) Lei Zhang et al. DNA AND CELL BIOLOGY
- Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis
- (2011) Finlay W. McNab et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Adjunctive therapy with interferon-gamma for the treatment of pulmonary tuberculosis: a systematic review
- (2011) X.-F. Gao et al. INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
- Immunosuppression in Patients Who Die of Sepsis and Multiple Organ Failure
- (2011) Jonathan S. Boomer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- The Role of Aspirin in Childhood Tuberculous Meningitis
- (2011) Johan F. Schoeman et al. JOURNAL OF CHILD NEUROLOGY
- Effect of immunomodulatory therapies in patients with pandemic influenza A (H1N1) 2009 complicated by pneumonia
- (2011) Diego Viasus et al. JOURNAL OF INFECTION
- Association Between Use of Statins and Mortality Among Patients Hospitalized With Laboratory-Confirmed Influenza Virus Infections: A Multistate Study
- (2011) M. L. Vandermeer et al. JOURNAL OF INFECTIOUS DISEASES
- High-dose vitamin D3 during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial
- (2011) Adrian R Martineau et al. LANCET
- Autophagy in immunity and inflammation
- (2011) Beth Levine et al. NATURE
- Phosphodiesterase 4 Inhibition Reduces Innate Immunity and Improves Isoniazid Clearance of Mycobacterium tuberculosis in the Lungs of Infected Mice
- (2011) Mi-Sun Koo et al. PLoS One
- Thermostable Hexameric Form of Eis (Rv2416c) Protein of M. tuberculosis Plays an Important Role for Enhanced Intracellular Survival within Macrophages
- (2011) Arsheed A. Ganaie et al. PLoS One
- Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus
- (2011) K. B. Walsh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The SARS-Coronavirus-Host Interactome: Identification of Cyclophilins as Target for Pan-Coronavirus Inhibitors
- (2011) Susanne Pfefferle et al. PLoS Pathogens
- The effect of vitamin A and zinc supplementation on treatment outcomes in pulmonary tuberculosis: a randomized controlled trial
- (2010) Marianne E Visser et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Original Article: Peroxisome proliferator-activated receptor and AMP-activated protein kinase agonists protect against lethal influenza virus challenge in mice
- (2010) Carson E. Moseley et al. Influenza and Other Respiratory Viruses
- Immunoparalysis and nosocomial infection in children with multiple organ dysfunction syndrome
- (2010) Mark W. Hall et al. INTENSIVE CARE MEDICINE
- Reactivation of tuberculosis during temsirolimus therapy
- (2010) Romain Coriat et al. INVESTIGATIONAL NEW DRUGS
- IL-7 Promotes T Cell Viability, Trafficking, and Functionality and Improves Survival in Sepsis
- (2010) J. Unsinger et al. JOURNAL OF IMMUNOLOGY
- Safety, Tolerability, and Mechanisms of Antiretroviral Activity of Pegylated Interferon Alfa‐2a in HIV‐1–Monoinfected Participants: A Phase II Clinical Trial
- (2010) David M. Asmuth et al. JOURNAL OF INFECTIOUS DISEASES
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- (2010) Wenqing Shui et al. JOURNAL OF PROTEOME RESEARCH
- Role of aspirin in tuberculous meningitis: A randomized open label placebo controlled trial
- (2010) U.K. Misra et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
- Réactivation d’une tuberculose sous bithérapie interféron-pégylé et ribavirine pour une hépatite chronique C
- (2010) N. Belkahla et al. REVUE DE MEDECINE INTERNE
- Randomized controlled trial of zinc and vitamin A as co-adjuvants for the treatment of pulmonary tuberculosis
- (2010) Lovett Lawson et al. TROPICAL MEDICINE & INTERNATIONAL HEALTH
- CCR5: From Natural Resistance to a New Anti-HIV Strategy
- (2010) Lucia Lopalco Viruses-Basel
- Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling
- (2010) Dong-Min Shin et al. PLoS Pathogens
- Granulocyte–Macrophage Colony-stimulating Factor to Reverse Sepsis-associated Immunosuppression
- (2009) Christian Meisel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Penitentiary or penthouse condo: the tuberculous granuloma from the microbe's point of view
- (2009) Carleitta Paige et al. CELLULAR MICROBIOLOGY
- Adalimumab Treatment of Life‐Threatening Tuberculosis
- (2009) Robert S. Wallis et al. CLINICAL INFECTIOUS DISEASES
- Differential cytokine/chemokines and KL-6 profiles in patients with different forms of tuberculosis
- (2009) Joel Fleury Djoba Siawaya et al. CYTOKINE
- The cyclophilin inhibitor Debio 025 combined with PEG IFNα2a significantly reduces viral load in treatment-naïve hepatitis C patients
- (2009) Robert Flisiak et al. HEPATOLOGY
- Successful Antiviral and Antituberculosis Treatment With Pegylated Interferon-alfa and Ribavirin in a Chronic Hepatitis C Patient With Pulmonary Tuberculosis
- (2009) Ming-Chao Tsai et al. JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION
- Novel signaling interactions between proteinase-activated receptor 2 and Toll-like receptors in vitro and in vivo
- (2009) Q M Nhu et al. Mucosal Immunology
- Long-Term Control of HIV byCCR5Delta32/Delta32 Stem-Cell Transplantation
- (2009) Gero Hütter et al. NEW ENGLAND JOURNAL OF MEDICINE
- Immunomodulation with Recombinant Interferon-γ1b in Pulmonary Tuberculosis
- (2009) Rod Dawson et al. PLoS One
- TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection
- (2009) J. R. Aldridge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Therapeutic Silencing of MicroRNA-122 in Primates with Chronic Hepatitis C Virus Infection
- (2009) R. E. Lanford et al. SCIENCE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
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- (2009) Artur Kaul et al. PLoS Pathogens
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- (2008) Yumiko Imai et al. CELL
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- (2008) Timothy K. Blackmore et al. CLINICAL INFECTIOUS DISEASES
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- (2008) L. E. Via et al. INFECTION AND IMMUNITY
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- (2008) F. Yang et al. JOURNAL OF VIROLOGY
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- (2008) Vijayakumar Velu et al. NATURE
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- (2008) Joerg Petersen et al. NATURE BIOTECHNOLOGY
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- (2008) B.-J. Zheng et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) A. K. Pandey et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) Seung Heon Lee et al. TUBERCULOSIS
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