CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease
出版年份 2016 全文链接
标题
CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease
作者
关键词
T helper cells, Mycobacterium tuberculosis, Spleen, T cells, Tuberculosis, Infectious disease control, Cell staining, Cytokines
出版物
PLoS Pathogens
Volume 12, Issue 5, Pages e1005667
出版商
Public Library of Science (PLoS)
发表日期
2016-06-01
DOI
10.1371/journal.ppat.1005667
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Tuberculosis reactivation in a patient receiving anti-programmed death-1 (PD-1) inhibitor for relapsed Hodgkin’s lymphoma
- (2016) Joycelyn J. X. Lee et al. ACTA ONCOLOGICA
- TB vaccines; promoting rapid and durable protection in the lung
- (2015) Peter Andersen et al. CURRENT OPINION IN IMMUNOLOGY
- Interleukin 27R regulates CD4+T cell phenotype and impacts protective immunity duringMycobacterium tuberculosisinfection
- (2015) Egidio Torrado et al. JOURNAL OF EXPERIMENTAL MEDICINE
- ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis
- (2015) Albanus O. Moguche et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8+T cells
- (2015) Pamela M. Odorizzi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A Novel Model for IFN-γ–Mediated Autoinflammatory Syndromes
- (2015) R. Lee Reinhardt et al. JOURNAL OF IMMUNOLOGY
- Interferon γ and Tumor Necrosis Factor Are Not Essential Parameters of CD4+T-Cell Responses for Vaccine Control of Tuberculosis
- (2015) Mark T. Orr et al. JOURNAL OF INFECTIOUS DISEASES
- Defining features of protective CD4 T cell responses to Mycobacterium tuberculosis
- (2014) Shunsuke Sakai et al. CURRENT OPINION IN IMMUNOLOGY
- IFN-gamma AU-rich element removal promotes chronic IFN-gamma expression and autoimmunity in mice
- (2014) Deborah L. Hodge et al. JOURNAL OF AUTOIMMUNITY
- Cutting Edge: Control of Mycobacterium tuberculosis Infection by a Subset of Lung Parenchyma-Homing CD4 T Cells
- (2014) S. Sakai et al. JOURNAL OF IMMUNOLOGY
- CD4+ T Cells Contain Early Extrapulmonary Tuberculosis (TB) Dissemination and Rapid TB Progression and Sustain Multieffector Functions of CD8+ T and CD3- Lymphocytes: Mechanisms of CD4+ T Cell Immunity
- (2014) S. Yao et al. JOURNAL OF IMMUNOLOGY
- Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk
- (2014) Katrin D. Mayer-Barber et al. NATURE
- Intravascular staining for discrimination of vascular and tissue leukocytes
- (2014) Kristin G Anderson et al. Nature Protocols
- Mendelian susceptibility to mycobacterial disease: Genetic, immunological, and clinical features of inborn errors of IFN-γ immunity
- (2014) Jacinta Bustamante et al. SEMINARS IN IMMUNOLOGY
- Tuberculosis vaccines – rethinking the current paradigm
- (2014) Peter Andersen et al. TRENDS IN IMMUNOLOGY
- iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis
- (2014) Alissa C. Rothchild et al. PLoS Pathogens
- The Immune Response in Tuberculosis
- (2013) Anne O'Garra et al. Annual Review of Immunology
- TNF Dually Mediates Resistance and Susceptibility to Mycobacteria via Mitochondrial Reactive Oxygen Species
- (2013) Francisco J. Roca et al. CELL
- Protection by BCG Vaccine Against Tuberculosis: A Systematic Review of Randomized Controlled Trials
- (2013) Punam Mangtani et al. CLINICAL INFECTIOUS DISEASES
- Cutting Edge: Direct Recognition of Infected Cells by CD4 T Cells Is Required for Control of Intracellular Mycobacterium tuberculosis In Vivo
- (2013) S. Srivastava et al. JOURNAL OF IMMUNOLOGY
- Lack of a Therapeutic Role for Interferon in Patients With Tuberculosis
- (2013) R. S. Wallis JOURNAL OF INFECTIOUS DISEASES
- Mycobacterium tuberculosis Exploits Human Interferon γ to Stimulate Macrophage Extracellular Trap Formation and Necrosis
- (2013) Ka-Wing Wong et al. JOURNAL OF INFECTIOUS DISEASES
- Safety and efficacy of MVA85A, a new tuberculosis vaccine, in infants previously vaccinated with BCG: a randomised, placebo-controlled phase 2b trial
- (2013) Michele D Tameris et al. LANCET
- A rheostat for immune responses: the unique properties of PD-1 and their advantages for clinical application
- (2013) Taku Okazaki et al. NATURE IMMUNOLOGY
- Prominent role for T cell-derived Tumour Necrosis Factor for sustained control of Mycobacterium tuberculosis infection
- (2013) Nasiema Allie et al. Scientific Reports
- CD4 T Cell Depletion Exacerbates Acute Mycobacterium tuberculosis While Reactivation of Latent Infection Is Dependent on Severity of Tissue Depletion in Cynomolgus Macaques
- (2012) Philana Ling Lin et al. AIDS RESEARCH AND HUMAN RETROVIRUSES
- Host Genotype-Specific Therapies Can Optimize the Inflammatory Response to Mycobacterial Infections
- (2012) David M. Tobin et al. CELL
- Programmed death 1 protects from fatal circulatory failure during systemic virus infection of mice
- (2012) Helge Frebel et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IFN- from CD4 T Cells Is Essential for Host Survival and Enhances CD8 T Cell Function during Mycobacterium tuberculosis Infection
- (2012) A. M. Green et al. JOURNAL OF IMMUNOLOGY
- Nitric oxide controls the immunopathology of tuberculosis by inhibiting NLRP3 inflammasome–dependent processing of IL-1β
- (2012) Bibhuti B Mishra et al. NATURE IMMUNOLOGY
- Mtb-Specific CD27low CD4 T Cells as Markers of Lung Tissue Destruction during Pulmonary Tuberculosis in Humans
- (2012) Irina Yu Nikitina et al. PLoS One
- Tuberculosis Pathogenesis and Immunity
- (2011) Jennifer A. Philips et al. Annual Review of Pathology-Mechanisms of Disease
- Innate and Adaptive Interferons Suppress IL-1α and IL-1β Production by Distinct Pulmonary Myeloid Subsets during Mycobacterium tuberculosis Infection
- (2011) Katrin D. Mayer-Barber et al. IMMUNITY
- Intravital Imaging Reveals Limited Antigen Presentation and T Cell Effector Function in Mycobacterial Granulomas
- (2011) Jackson G. Egen et al. IMMUNITY
- Regulation of neutrophils by interferon-γ limits lung inflammation during tuberculosis infection
- (2011) Bisweswar Nandi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- A recombinant Mycobacterium smegmatis induces potent bactericidal immunity against Mycobacterium tuberculosis
- (2011) Kari A Sweeney et al. NATURE MEDICINE
- A multistage tuberculosis vaccine that confers efficient protection before and after exposure
- (2011) Claus Aagaard et al. NATURE MEDICINE
- T Cells from Programmed Death-1 Deficient Mice Respond Poorly to Mycobacterium tuberculosis Infection
- (2011) Sultan Tousif et al. PLoS One
- Suboptimal Activation of Antigen-Specific CD4+ Effector Cells Enables Persistence of M. tuberculosis In Vivo
- (2011) Tyler D. Bold et al. PLoS Pathogens
- A Gamma Interferon Independent Mechanism of CD4 T Cell Mediated Control of M. tuberculosis Infection in vivo
- (2011) Alena M. Gallegos et al. PLoS Pathogens
- Specific T Cell Frequency and Cytokine Expression Profile Do Not Correlate with Protection against Tuberculosis after Bacillus Calmette-Guérin Vaccination of Newborns
- (2010) Benjamin M. N. Kagina et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- CD4 T Cells Promote Rather than Control Tuberculosis in the Absence of PD-1-Mediated Inhibition
- (2010) D. L. Barber et al. JOURNAL OF IMMUNOLOGY
- Anticytokine autoantibodies in infectious diseases: pathogenesis and mechanisms
- (2010) Sarah K Browne et al. LANCET INFECTIOUS DISEASES
- Distinct functions of antigen-specific CD4 T cells during murine Mycobacterium tuberculosis infection
- (2010) W. W. Reiley et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Programmed death-1 (PD-1)-deficient mice are extraordinarily sensitive to tuberculosis
- (2010) E. Lazar-Molnar et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Defined Tuberculosis Vaccine Candidate Boosts BCG and Protects Against Multidrug-Resistant Mycobacterium tuberculosis
- (2010) S. Bertholet et al. Science Translational Medicine
- Cell-Mediated Immune Responses in Tuberculosis
- (2009) Andrea M. Cooper Annual Review of Immunology
- Interferon-γ-Responsive Nonhematopoietic Cells Regulate the Immune Response to Mycobacterium tuberculosis
- (2009) Ludovic Desvignes et al. IMMUNITY
- Cytotoxicity and Secretion of Gamma Interferon Are Carried Out by Distinct CD8 T Cells during Mycobacterium tuberculosis Infection
- (2009) T. Einarsdottir et al. INFECTION AND IMMUNITY
- Genetic deficiencies of innate immune signalling in human infectious disease
- (2009) Esther van de Vosse et al. LANCET INFECTIOUS DISEASES
- PD-1 and Its Ligands in Tolerance and Immunity
- (2008) Mary E. Keir et al. Annual Review of Immunology
- Enhancing therapeutic vaccination by blocking PD-1–mediated inhibitory signals during chronic infection
- (2008) Sang-Jun Ha et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Selective expansion of a subset of exhausted CD8 T cells by PD-L1 blockade
- (2008) S. D. Blackburn et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started