Influenza virus replication in macrophages: balancing protection and pathogenesis

Emerging highly pathogenic H5 avian influenza viruses in France during winter 2015/16: phylogenetic analyses and markers for zoonotic potential

(2017) François-Xavier Briand et al.   Eurosurveillance

Widespread Virus Replication in Alveoli Drives Acute Respiratory Distress Syndrome in Aerosolized H5N1 Influenza Infection of Macaques

(2017) Elizabeth R. Wonderlich et al.   JOURNAL OF IMMUNOLOGY

Class I PI3K inhibitor ZSTK474 mediates a shift in microglial/macrophage phenotype and inhibits inflammatory response in mice with cerebral ischemia/reperfusion injury

(2016) Po Wang et al.   Journal of Neuroinflammation

Influenza Virus Overcomes Cellular Blocks To Productively Replicate, Impacting Macrophage Function

(2016) Shauna A. Marvin et al.   JOURNAL OF VIROLOGY

Role for migratory wild birds in the global spread of avian influenza H5N8

(2016)   SCIENCE

Swine alveolar macrophage cell model allows optimal replication of influenza A viruses regardless of their origin

(2016) Samantha B. Kasloff et al.   VIROLOGY

Susceptibility of bone marrow-derived macrophages to influenza virus infection is dependent on macrophage phenotype

(2015) Gillian M. Campbell et al.   JOURNAL OF GENERAL VIROLOGY

Infection of Mouse Macrophages by Seasonal Influenza Viruses Can Be Restricted at the Level of Virus Entry and at a Late Stage in the Virus Life Cycle

(2015) Sarah L. Londrigan et al.   JOURNAL OF VIROLOGY

Understanding the Mysterious M2 Macrophage through Activation Markers and Effector Mechanisms

(2015) Tamás Rőszer   MEDIATORS OF INFLAMMATION

Multi-spectral fluorescent reporter influenza viruses (Color-flu) as powerful tools for in vivo studies

(2015) Satoshi Fukuyama et al.   Nature Communications

Novel Markers to Delineate Murine M1 and M2 Macrophages

(2015) Kyle A. Jablonski et al.   PLoS One

Transient ablation of alveolar macrophages leads to massive pathology of influenza infection without affecting cellular adaptive immunity

(2014) Christina Purnama et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of Proinflammatory Cytokines in Primary Human Macrophages by Influenza A Virus (H5N1) Is Selectively Regulated by IFN Regulatory Factor 3 and p38 MAPK

(2014) K. P. Y. Hui et al.   JOURNAL OF IMMUNOLOGY

Recombinant human mannose-binding lectin dampens human alveolar macrophage inflammatory responses to influenza A virus in vitro

(2014) Benjamin Nelson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

SAMHD1 Restricts HIV-1 Replication and Regulates Interferon Production in Mouse Myeloid Cells

(2014) Ruonan Zhang et al.   PLoS One

PI3K/Akt Signaling Pathway Modulates Influenza Virus Induced Mouse Alveolar Macrophage Polarization to M1/M2b

(2014) Xiangfeng Zhao et al.   PLoS One

Alveolar Macrophages Are Essential for Protection from Respiratory Failure and Associated Morbidity following Influenza Virus Infection

(2014) Christoph Schneider et al.   PLoS Pathogens

Histopathological Evaluation of the Diversity of Cells Susceptible to H5N1 Virulent Avian Influenza Virus

(2013) Haru Ogiwara et al.   AMERICAN JOURNAL OF PATHOLOGY

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

(2013) H. E. Ghoneim et al.   JOURNAL OF IMMUNOLOGY

Addition of Glycosylation to Influenza A Virus Hemagglutinin Modulates Antibody-Mediated Recognition of H1N1 2009 Pandemic Viruses

(2013) E. R. Job et al.   JOURNAL OF IMMUNOLOGY

The Macrophage Galactose-Type Lectin Can Function as an Attachment and Entry Receptor for Influenza Virus

(2013) W. C. Ng et al.   JOURNAL OF VIROLOGY

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Replication and Pathogenesis in Mice

(2013) H. Zaraket et al.   JOURNAL OF VIROLOGY

Receptor specificity does not affect replication or virulence of the 2009 pandemic H1N1 influenza virus in mice and ferrets

(2013) Seema S. Lakdawala et al.   VIROLOGY

Macrophage-expressed IFN-β Contributes to Apoptotic Alveolar Epithelial Cell Injury in Severe Influenza Virus Pneumonia

(2013) Katrin Högner et al.   PLoS Pathogens

The fate of influenza A virus after infection of human macrophages and dendritic cells

(2012) K. R. Short et al.   JOURNAL OF GENERAL VIROLOGY

Highly pathogenic avian influenza viruses inhibit effective immune responses of human blood-derived macrophages

(2012) Judith Friesenhagen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Mammalian Innate Resistance to Highly Pathogenic Avian Influenza H5N1 Virus Infection Is Mediated through Reduced Proinflammation and Infectious Virus Release

(2012) R. K. Nelli et al.   JOURNAL OF VIROLOGY

The Hemagglutinin Protein of Highly Pathogenic H5N1 Influenza Viruses Overcomes an Early Block in the Replication Cycle To Promote Productive Replication in Macrophages

(2012) Troy D. Cline et al.   JOURNAL OF VIROLOGY

Innate Immune Response of Human Alveolar Macrophages during Influenza A Infection

(2012) Jieru Wang et al.   PLoS One

Influenza Virus A Infection of Human Monocyte and Macrophage Subpopulations Reveals Increased Susceptibility Associated with Cell Differentiation

(2012) Marieke A. Hoeve et al.   PLoS One

The Distribution of Macrophages with a M1 or M2 Phenotype in Relation to Prognosis and the Molecular Characteristics of Colorectal Cancer

(2012) Sofia Edin et al.   PLoS One

Proinflammatory Cytokine Response and Viral Replication in Mouse Bone Marrow Derived Macrophages Infected with Influenza H1N1 and H5N1 Viruses

(2012) Renee W. Y. Chan et al.   PLoS One

Lack of the pattern recognition molecule mannose-binding lectin increases susceptibility to influenza A virus infection

(2011) Wei-Chuan Chang et al.   BMC IMMUNOLOGY

Cytokine production by primary human macrophages infected with highly pathogenic H5N1 or pandemic H1N1 2009 influenza viruses

(2011) S. Sakabe et al.   JOURNAL OF GENERAL VIROLOGY

Increased Pathogenicity of a Reassortant 2009 Pandemic H1N1 Influenza Virus Containing an H5N1 Hemagglutinin

(2011) T. D. Cline et al.   JOURNAL OF VIROLOGY

Viral Replication and Innate Host Responses in Primary Human Alveolar Epithelial Cells and Alveolar Macrophages Infected with Influenza H5N1 and H1N1 Viruses

(2011) W. C. L. Yu et al.   JOURNAL OF VIROLOGY

Glycosylation Site Alteration in the Evolution of Influenza A (H1N1) Viruses

(2011) Shisheng Sun et al.   PLoS One

Responses of Mouse Airway Epithelial Cells and Alveolar Macrophages to Virulent and Avirulent Strains of Influenza A Virus

(2011) Michelle D. Tate et al.   VIRAL IMMUNOLOGY

Quantitative Subcellular Proteome and Secretome Profiling of Influenza A Virus-Infected Human Primary Macrophages

(2011) Niina Lietzén et al.   PLoS Pathogens

Highly Pathogenic Avian Influenza Virus H5N1 Infects Alveolar Macrophages without Virus Production or Excessive TNF-Alpha Induction

(2011) Debby van Riel et al.   PLoS Pathogens

Induction of TNF-α in human macrophages by avian and human influenza viruses

(2010) Yuwarat Monteerarat et al.   ARCHIVES OF VIROLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

The receptor preference of influenza viruses

(2010) Bo Meng et al.   Influenza and Other Respiratory Viruses

Influenza Virus Inactivation for Studies of Antigenicity and Phenotypic Neuraminidase Inhibitor Resistance Profiling

(2010) Marcel Jonges et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Critical Role of Airway Macrophages in Modulating Disease Severity during Influenza Virus Infection of Mice

(2010) M. D. Tate et al.   JOURNAL OF VIROLOGY

Comparison of pro-inflammatory cytokine expression and cellular signal transduction in human macrophages infected with different influenza A viruses

(2010) Janina Geiler et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

(2010) B. Manicassamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stabilin-1 mediates phosphatidylserine-dependent clearance of cell corpses in alternatively activated macrophages

(2009) S.-Y. Park et al.   JOURNAL OF CELL SCIENCE

The pH of Activation of the Hemagglutinin Protein Regulates H5N1 Influenza Virus Pathogenicity and Transmissibility in Ducks

(2009) M. L. Reed et al.   JOURNAL OF VIROLOGY

Systems-Level Comparison of Host-Responses Elicited by Avian H5N1 and Seasonal H1N1 Influenza Viruses in Primary Human Macrophages

(2009) Suki M. Y. Lee et al.   PLoS One

Canine Influenza Virus Replicates in Alveolar Macrophages and Induces TNF-α

(2009) J. R. Powe et al.   VETERINARY PATHOLOGY

Infection and replication of avian influenza H5N1 virus in an infected human

(2009) Jing-Jiao Zhou et al.   VIRUS GENES

Pathogenesis of emerging avian influenza viruses in mammals and the host innate immune response

(2008) Taronna R. Maines et al.   IMMUNOLOGICAL REVIEWS

Alveolar Macrophages Are Indispensable for Controlling Influenza Viruses in Lungs of Pigs

(2008) H. M. Kim et al.   JOURNAL OF VIROLOGY

Modulation of viral replication in macrophages persistently infected with the DA strain of Theiler's murine encephalomyelitis virus

(2008) Stephane Steurbaut et al.   Virology Journal

Domestic Pigs Have Low Susceptibility to H5N1 Highly Pathogenic Avian Influenza Viruses

(2008) Aleksandr S. Lipatov et al.   PLoS Pathogens

The Evolutionary Genetics and Emergence of Avian Influenza Viruses in Wild Birds

(2008) Vivien G. Dugan et al.   PLoS Pathogens

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens