标题
Cellular senescence: from growth arrest to immunogenic conversion
作者
关键词
Immunogenic, Senescence, Immune surveillance, Apoptosis resistance, Secretome, NKG2D
出版物
AGE
Volume 37, Issue 2, Pages -
出版商
Springer Nature
发表日期
2015-03-19
DOI
10.1007/s11357-015-9764-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- IL1- and TGFβ-Nox4 signaling, oxidative stress and DNA damage response are shared features of replicative, oncogene-induced, and drug-induced paracrine ‘Bystander senescence’
- (2016) Sona Hubackova et al. Aging-US
- A genomics approach identifies senescence-specific gene expression regulation
- (2014) Daniel H. Lackner et al. AGING CELL
- BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy
- (2014) Lisa M Lindqvist et al. Autophagy
- Senescent cells: SASPected drivers of age-related pathologies
- (2014) Yossi Ovadya et al. BIOGERONTOLOGY
- TGF-β1 induces senescence of bone marrow mesenchymal stem cells via increase of mitochondrial ROS production
- (2014) Junfang Wu et al. BMC DEVELOPMENTAL BIOLOGY
- Physiological and pathological consequences of cellular senescence
- (2014) Dominick G. A. Burton et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cellular senescence occurred widespread to multiple selective sites in the fetal tissues and organs of mice
- (2014) Kexiong Zhang et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Aging: not all DNA damage is equal
- (2014) Wilbert P Vermeij et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
- (2014) Marco Demaria et al. DEVELOPMENTAL CELL
- p38 signaling inhibits mTORC1-independent autophagy in senescent human CD8+ T cells
- (2014) Sian M. Henson et al. JOURNAL OF CLINICAL INVESTIGATION
- Inflammation-induced DNA damage and damage-induced inflammation: a vicious cycle
- (2014) Timea Pálmai-Pallag et al. MICROBES AND INFECTION
- Geriatric muscle stem cells switch reversible quiescence into senescence
- (2014) Pedro Sousa-Victor et al. NATURE
- The kinase p38 activated by the metabolic regulator AMPK and scaffold TAB1 drives the senescence of human T cells
- (2014) Alessio Lanna et al. NATURE IMMUNOLOGY
- IL-6 secreted by cancer-associated fibroblasts induces tamoxifen resistance in luminal breast cancer
- (2014) X Sun et al. ONCOGENE
- ATM Regulates Insulin-Like Growth Factor 1-Secretory Clusterin (IGF-1-sCLU) Expression that Protects Cells against Senescence
- (2014) Xiuquan Luo et al. PLoS One
- Stable Cellular Senescence Is Associated with Persistent DDR Activation
- (2014) Marzia Fumagalli et al. PLoS One
- Enhancing Chemotherapy Efficacy in Pten -Deficient Prostate Tumors by Activating the Senescence-Associated Antitumor Immunity
- (2014) Alberto Toso et al. Cell Reports
- Chromatin modifications and DNA repair: beyond double-strand breaks
- (2014) Nealia C. M. House et al. Frontiers in Genetics
- Senescent endothelial cells are prone to TNF-α-induced cell death due to expression of FAS receptor
- (2013) Hyeona Jeon et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Immunosurveillance of senescent cells: the bright side of the senescence program
- (2013) Adi Sagiv et al. BIOGERONTOLOGY
- Dynamics of Senescent Cell Formation and Retention Revealed by p14ARF Induction in the Epidermis
- (2013) R. Tokarsky-Amiel et al. CANCER RESEARCH
- Chromatin Remodeling at DNA Double-Strand Breaks
- (2013) Brendan D. Price et al. CELL
- Non-Cell-Autonomous Tumor Suppression by p53
- (2013) Amaia Lujambio et al. CELL
- Programmed Cell Senescence during Mammalian Embryonic Development
- (2013) Daniel Muñoz-Espín et al. CELL
- Senescence Is a Developmental Mechanism that Contributes to Embryonic Growth and Patterning
- (2013) Mekayla Storer et al. CELL
- DNA Damage Triggers a Chronic Autoinflammatory Response, Leading to Fat Depletion in NER Progeria
- (2013) Ismene Karakasilioti et al. Cell Metabolism
- Receptor for advanced glycation end-products promotes premature senescence of proximal tubular epithelial cells via activation of endoplasmic reticulum stress-dependent p21 signaling
- (2013) Jun Liu et al. CELLULAR SIGNALLING
- The DNA damage response induces antigen presenting cell-like functions in fibroblasts
- (2013) Melissa Li Fang Tang et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Cell fusion induced by ERVWE1 or measles virus causes cellular senescence
- (2013) A. Chuprin et al. GENES & DEVELOPMENT
- p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
- (2013) Albert R. Davalos et al. JOURNAL OF CELL BIOLOGY
- Matricellular Protein CCN1 Promotes Regression of Liver Fibrosis through Induction of Cellular Senescence in Hepatic Myofibroblasts
- (2013) K.-H. Kim et al. MOLECULAR AND CELLULAR BIOLOGY
- T-helper-1-cell cytokines drive cancer into senescence
- (2013) Heidi Braumüller et al. NATURE
- TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells
- (2013) Annamaria Biroccio et al. NATURE CELL BIOLOGY
- Senescent cells harbour features of the cancer epigenome
- (2013) Hazel A. Cruickshanks et al. NATURE CELL BIOLOGY
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Mechanisms and models of somatic cell reprogramming
- (2013) Yosef Buganim et al. NATURE REVIEWS GENETICS
- Cellular senescence mediated by p16INK4A-coupled miRNA pathways
- (2013) Marita G. Overhoff et al. NUCLEIC ACIDS RESEARCH
- The Pro-Survival Role of Autophagy Depends on Bcl-2 Under Nutrition Stress Conditions
- (2013) Hai-Dong Xu et al. PLoS One
- Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
- (2012) Diana Jurk et al. AGING CELL
- Autophagy-dependent senescence in response to DNA damage and chronic apoptotic stress
- (2012) Kamini Singh et al. Autophagy
- ATM-deficient human fibroblast cells are resistant to low levels of DNA double-strand break induced apoptosis and subsequently undergo drug-induced premature senescence
- (2012) Jun Park et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- DNA Damage Response and Inflammatory Signaling Limit the MLL-ENL-Induced Leukemogenesis In Vivo
- (2012) Sylvia Takacova et al. CANCER CELL
- MicroRNAs and DNA damage response
- (2012) Yemin Wang et al. CELL CYCLE
- Endoplasmic reticulum stress inhibits cell cycle progression via induction of p27 in melanoma cells
- (2012) Chuanchun Han et al. CELLULAR SIGNALLING
- Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells
- (2012) Simon Asbjørn Larsen et al. Chemistry Central Journal
- Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions
- (2012) Anitha Suram et al. EMBO JOURNAL
- Common Fragile Sites: Genomic Hotspots of DNA Damage and Carcinogenesis
- (2012) Ke Ma et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Senescence determines the fate of activated rat pancreatic stellate cells
- (2012) Brit Fitzner et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells
- (2012) Moussa Benhamed et al. NATURE CELL BIOLOGY
- Granule exocytosis mediates immune surveillance of senescent cells
- (2012) A Sagiv et al. ONCOGENE
- DNA damage, discoordinated gene expression and cellular senescence in osteoarthritic chondrocytes
- (2012) J. Rose et al. OSTEOARTHRITIS AND CARTILAGE
- Cellular senescence induced by CD158d reprograms natural killer cells to promote vascular remodeling
- (2012) S. Rajagopalan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells
- (2012) Dasa Dolezalova et al. STEM CELLS
- ER stress-induced inflammation: does it aid or impede disease progression?
- (2012) Abhishek D. Garg et al. TRENDS IN MOLECULAR MEDICINE
- JNK2 is activated during ER stress and promotes cell survival
- (2012) M Raciti et al. Cell Death & Disease
- Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
- (2012) Graeme Hewitt et al. Nature Communications
- MicroRNAs as a novel cellular senescence regulator
- (2011) Feng-Jiao Liu et al. AGEING RESEARCH REVIEWS
- Loss of p21CDKN1Aimpairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence
- (2011) Paola Perucca et al. CELL CYCLE
- ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks
- (2011) Ashraf Khalil et al. CELL CYCLE
- p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
- (2011) Adam Freund et al. EMBO JOURNAL
- Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity
- (2011) Y. Chien et al. GENES & DEVELOPMENT
- NF-κB Regulates MICA Gene Transcription in Endothelial Cell through a Genetically Inhibitable Control Site
- (2011) Da Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tumor Suppressor and Aging Biomarker p16INK4aInduces Cellular Senescence without the Associated Inflammatory Secretory Phenotype
- (2011) Jean-Philippe Coppé et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- DNA damage and autophagy
- (2011) Humberto Rodriguez-Rocha et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
- (2011) Tae-Won Kang et al. NATURE
- ROS-generating NADPH oxidase NOX4 is a critical mediator in oncogenic H-Ras-induced DNA damage and subsequent senescence
- (2011) U Weyemi et al. ONCOGENE
- NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells
- (2011) E Crescenzi et al. ONCOGENE
- DNA double-strand break – induced pro-survival signaling
- (2011) Amy J. Hawkins et al. RADIOTHERAPY AND ONCOLOGY
- Protein modification and replicative senescence of WI-38 human embryonic fibroblasts
- (2010) Emad K. Ahmed et al. AGING CELL
- Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
- (2010) Shunsuke Minagawa et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Tumor Stroma-Derived TGF-β Limits Myc-Driven Lymphomagenesis via Suv39h1-Dependent Senescence
- (2010) Maurice Reimann et al. CANCER CELL
- CD4+ T Cells Contribute to the Remodeling of the Microenvironment Required for Sustained Tumor Regression upon Oncogene Inactivation
- (2010) Kavya Rakhra et al. CANCER CELL
- DNA Damage-Mediated Induction of a Chemoresistant Niche
- (2010) Luke A. Gilbert et al. CELL
- Cellular quiescence caused by the Mdm2 inhibitor Nutlin-3A
- (2010) Lioubov G. Korotchkina et al. CELL CYCLE
- Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
- (2010) Feifan Zhou et al. FEBS Journal
- Transforming growth factor-beta induces senescence in hepatocellular carcinoma cells and inhibits tumor growth
- (2010) Serif Senturk et al. HEPATOLOGY
- Endoplasmic Reticulum Stress Induces G2 Cell-Cycle Arrest via mRNA Translation of the p53 Isoform p53/47
- (2010) Karima Bourougaa et al. MOLECULAR CELL
- Feedback between p21 and reactive oxygen production is necessary for cell senescence
- (2010) João F Passos et al. Molecular Systems Biology
- The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
- (2010) Joon-Il Jun et al. NATURE CELL BIOLOGY
- A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen
- (2010) Jean-Philippe Coppé et al. PLoS One
- Spatial p21 expression profile in the mid-term mouse embryo
- (2010) Douglas B. Vasey et al. TRANSGENIC RESEARCH
- Regulation of autophagy by ROS: physiology and pathology
- (2010) Ruth Scherz-Shouval et al. TRENDS IN BIOCHEMICAL SCIENCES
- DNA damage response and cellular senescence in tissues of aging mice
- (2009) Chunfang Wang et al. AGING CELL
- A systematic review of humoral immune responses against tumor antigens
- (2009) Miriam Reuschenbach et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Microarray analysis of senescent vascular smooth muscle cells: A link to atherosclerosis and vascular calcification
- (2009) Dominick G.A. Burton et al. EXPERIMENTAL GERONTOLOGY
- New twist on the regulation of NKG2D ligand expression: Figure 1.
- (2009) Adelheid Cerwenka JOURNAL OF EXPERIMENTAL MEDICINE
- Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion
- (2009) Francis Rodier et al. NATURE CELL BIOLOGY
- Cellular senescence, ageing and disease
- (2008) D. G. A. Burton AGE
- Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts
- (2008) Henrik Sejersen et al. BIOGERONTOLOGY
- ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype
- (2008) A. Soriani et al. BLOOD
- Selective Induction of Expression of a Ligand for the NKG2D Receptor by Proteasome Inhibitors
- (2008) M. Vales-Gomez et al. CANCER RESEARCH
- Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network
- (2008) Thomas Kuilman et al. CELL
- Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence
- (2008) Juan C. Acosta et al. CELL
- Senescence of Activated Stellate Cells Limits Liver Fibrosis
- (2008) Valery Krizhanovsky et al. CELL
- A transcriptomic analysis of the EK1.Br strain of human fibroblastoid keratocytes: The effects of growth, quiescence and senescence
- (2008) David Kipling et al. EXPERIMENTAL EYE RESEARCH
- Identification of replicative senescence-associated genes in human umbilical vein endothelial cells by an annealing control primer system
- (2008) Tae Woo Kim et al. EXPERIMENTAL GERONTOLOGY
- p21Cip1 protects against oxidative stress by suppressing ER-dependent activation of mitochondrial death pathways
- (2008) P VITIELLO et al. FREE RADICAL BIOLOGY AND MEDICINE
- ATR signaling can drive cells into senescence in the absence of DNA breaks
- (2008) L. I. Toledo et al. GENES & DEVELOPMENT
- Human microRNAs regulate stress-induced immune responses mediated by the receptor NKG2D
- (2008) Noam Stern-Ginossar et al. NATURE IMMUNOLOGY
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
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