TRF2 inhibits a cell-extrinsic pathway through which natural killer cells eliminate cancer cells

Moderate expression of TRF2 in the hematopoietic system increases development of large cell blastic T-cell lymphomas

(2016) Sebastian Begemann et al.   Aging-US

Telomere protection and TRF2 expression are enhanced by the canonical Wnt signalling pathway

(2013) Irmina Diala et al.   EMBO REPORTS

A two-step mechanism for TRF2-mediated chromosome-end protection

(2013) Keiji Okamoto et al.   NATURE

One Identity or More for Telomeres?

(2013) Marie-Josèphe Giraud-Panis et al.   Frontiers in Oncology

Telomerase Reactivation following Telomere Dysfunction Yields Murine Prostate Tumors with Bone Metastases

(2012) Zhihu Ding et al.   CELL

The human TTAGGG repeat factors 1 and 2 bind to a subset of interstitial telomeric sequences and satellite repeats

(2011) Thomas Simonet et al.   CELL RESEARCH

Human telomeric proteins occupy selective interstitial sites

(2011) Dong Yang et al.   CELL RESEARCH

Elevated TRF2 in advanced breast cancers with short telomeres

(2010) Malissa C. Diehl et al.   BREAST CANCER RESEARCH AND TREATMENT

Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric cancer

(2010) Hua Hu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression

(2010) Hsiangling Teo et al.   NATURE CELL BIOLOGY

Telomeric repeats far from the ends: mechanisms of origin and role in evolution

(2009) A. Ruiz-Herrera et al.   CYTOGENETIC AND GENOME RESEARCH

Upregulation and CpG Island Hypomethylation of the TRF2 Gene in Human Gastric Cancer

(2009) Wenjie Dong et al.   DIGESTIVE DISEASES AND SCIENCES

In VivoStoichiometry of Shelterin Components

(2009) Kaori K. Takai et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The B7 family member B7-H6 is a tumor cell ligand for the activating natural killer cell receptor NKp30 in humans

(2009) Cameron S. Brandt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

ATM-ATR-dependent up-regulation of DNAM-1 and NKG2D ligands on multiple myeloma cells by therapeutic agents results in enhanced NK-cell susceptibility and is associated with a senescent phenotype

(2008) A. Soriani et al.   BLOOD

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY