Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy
出版年份 2016 全文链接
标题
Tumor Metabolism, the Ketogenic Diet and β-Hydroxybutyrate: Novel Approaches to Adjuvant Brain Tumor Therapy
作者
关键词
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出版物
Frontiers in Molecular Neuroscience
Volume 9, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2016-11-16
DOI
10.3389/fnmol.2016.00122
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Enhanced immunity in a mouse model of malignant glioma is mediated by a therapeutic ketogenic diet
- (2016) Danielle M. Lussier et al. BMC CANCER
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- Emerging Approaches for Targeting Metabolic Vulnerabilities in Malignant Glioma
- (2016) Peter M. Clark et al. Current Neurology and Neuroscience Reports
- PI3K/Akt/mTOR and Ras/Raf/MEK/ERK signaling pathways inhibitors as anticancer agents: Structural and pharmacological perspectives
- (2016) Vivek Asati et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Acetate as a Metabolic and Epigenetic Modifier of Cancer Therapy
- (2016) Diane M. Jaworski et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Facilitative glucose transporters: Implications for cancer detection, prognosis and treatment
- (2016) Carly C. Barron et al. METABOLISM-CLINICAL AND EXPERIMENTAL
- Energy disruptors: rising stars in anticancer therapy?
- (2016) F Bost et al. Oncogenesis
- T Cells and Cancer: How Metabolism Shapes Immunity
- (2016) Barbara Molon et al. Frontiers in Immunology
- A new way to produce hyperketonemia: Use of ketone ester in a case of Alzheimer's disease
- (2015) Mary T. Newport et al. Alzheimers & Dementia
- Growth of Human Colon Cancer Cells in Nude Mice is Delayed by Ketogenic Diet With or Without Omega-3 Fatty Acids and Medium-chain Triglycerides
- (2015) Guang-Wei Hao et al. Asian Pacific Journal of Cancer Prevention
- The emerging roles of microRNAs in cancer metabolism
- (2015) Brian Chan et al. CANCER LETTERS
- Abstract 240: The ketogenic diet alters the expression of microRNAs that play key roles in tumor development
- (2015) Julia Pazmandi et al. CANCER RESEARCH
- Abstract 3346: The ketone body β-hydroxybutyrate increases radiosensitivity in glioma cell lines in vitro
- (2015) Alex P. Rossi et al. CANCER RESEARCH
- Metabolic reprogramming and dysregulated metabolism: cause, consequence and/or enabler of environmental carcinogenesis?
- (2015) R.Brooks Robey et al. CARCINOGENESIS
- Lactate promotes glutamine uptake and metabolism in oxidative cancer cells
- (2015) Jhudit Pérez-Escuredo et al. CELL CYCLE
- MYC Disrupts the Circadian Clock and Metabolism in Cancer Cells
- (2015) Brian J. Altman et al. Cell Metabolism
- A Supplemented High-Fat Low-Carbohydrate Diet for the Treatment of Glioblastoma
- (2015) R. T. Martuscello et al. CLINICAL CANCER RESEARCH
- Metabolic and mind shifts
- (2015) Cyril Corbet et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Anti-Inflammatory and Pro-Resolving Effects of N-3 PUFA in Cancers: Structures and Mechanisms
- (2015) Qi Wang et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Emerging concepts in bioenergetics and cancer research: Metabolic flexibility, coupling, symbiosis, switch, oxidative tumors, metabolic remodeling, signaling and bioenergetic therapy
- (2015) Emilie Obre et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Molecular Connections between Cancer Cell Metabolism and the Tumor Microenvironment
- (2015) Calvin Justus et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cancer metabolism and the Warburg effect: the role of HIF-1 and PI3K
- (2015) Rupert Courtnay et al. MOLECULAR BIOLOGY REPORTS
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome–mediated inflammatory disease
- (2015) Yun-Hee Youm et al. NATURE MEDICINE
- ATPS-77THE KETONE BODY ß-HYDROXYBUTYRATE RADIOSENSITIZES GLIOBLASTOMA MULTIFORME STEM CELLS
- (2015) Helena B. Silva-Nichols et al. NEURO-ONCOLOGY
- Non-Toxic Metabolic Management of Metastatic Cancer in VM Mice: Novel Combination of Ketogenic Diet, Ketone Supplementation, and Hyperbaric Oxygen Therapy
- (2015) A. M. Poff et al. PLoS One
- Cancer prevention and therapy through the modulation of the tumor microenvironment
- (2015) Stephanie C. Casey et al. SEMINARS IN CANCER BIOLOGY
- MYC and metabolism on the path to cancer
- (2015) Annie L. Hsieh et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Regulation of mTORC1 by PI3K signaling
- (2015) Christian C. Dibble et al. TRENDS IN CELL BIOLOGY
- MYC, Metabolism, and Cancer
- (2015) Z. E. Stine et al. Cancer Discovery
- The Interaction between Epigenetics, Nutrition and the Development of Cancer
- (2015) Karen Bishop et al. Nutrients
- The Ketogenic Diet Alters the Hypoxic Response and Affects Expression of Proteins Associated with Angiogenesis, Invasive Potential and Vascular Permeability in a Mouse Glioma Model
- (2015) Eric C. Woolf et al. PLoS One
- Regulation of glucose metabolism by p53: Emerging new roles for the tumor suppressor
- (2015) Esha Madan et al. Oncotarget
- PI3K/AKT signaling pathway and cancer: an updated review
- (2014) Miriam Martini et al. ANNALS OF MEDICINE
- Calories, carbohydrates, and cancer therapy with radiation: exploiting the five R’s through dietary manipulation
- (2014) Rainer J. Klement et al. CANCER AND METASTASIS REVIEWS
- Long-Chain Fatty Acid Analogues Suppress Breast Tumorigenesis and Progression
- (2014) U. Gluschnaider et al. CANCER RESEARCH
- Hexokinase II integrates energy metabolism and cellular protection: Akting on mitochondria and TORCing to autophagy
- (2014) D J Roberts et al. CELL DEATH AND DIFFERENTIATION
- Interplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogramming
- (2014) B. M. M. Zwaans et al. Disease Models & Mechanisms
- The level of patient-reported outcome reporting in randomised controlled trials of brain tumour patients: A systematic review
- (2014) Linda Dirven et al. EUROPEAN JOURNAL OF CANCER
- Ketone supplementation decreases tumor cell viability and prolongs survival of mice with metastatic cancer
- (2014) A.M. Poff et al. INTERNATIONAL JOURNAL OF CANCER
- Ketone ester effects on metabolism and transcription
- (2014) Richard L. Veech JOURNAL OF LIPID RESEARCH
- Ketogenic diets, mitochondria, and neurological diseases
- (2014) Lindsey B. Gano et al. JOURNAL OF LIPID RESEARCH
- Targeting metabolism with a ketogenic diet during the treatment of glioblastoma multiforme
- (2014) Colin E. Champ et al. JOURNAL OF NEURO-ONCOLOGY
- Roles of Caloric Restriction, Ketogenic Diet and Intermittent Fasting during Initiation, Progression and Metastasis of Cancer in Animal Models: A Systematic Review and Meta-Analysis
- (2014) Mengmeng Lv et al. PLoS One
- Dietary PUFA and cancer
- (2014) S. Abel et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages
- (2014) Mahbubur Rahman et al. Nature Communications
- Ketogenic diets as an adjuvant cancer therapy: History and potential mechanism
- (2014) Bryan G. Allen et al. Redox Biology
- Ionizing Radiation-Induced DNA Damage, Response, and Repair
- (2013) Wil L. Santivasi et al. ANTIOXIDANTS & REDOX SIGNALING
- Caloric restriction augments radiation efficacy in breast cancer
- (2013) Anthony Saleh et al. CELL CYCLE
- Ketogenic Diets Enhance Oxidative Stress and Radio-Chemo-Therapy Responses in Lung Cancer Xenografts
- (2013) B. G. Allen et al. CLINICAL CANCER RESEARCH
- Regulation of the Metabolism of Polyunsaturated Fatty Acids and Butyrate in Colon Cancer Cells
- (2013) Jirina Hofmanova et al. CURRENT PHARMACEUTICAL BIOTECHNOLOGY
- Selectively starving cancer cells through dietary manipulation: methods and clinical implications
- (2013) Brittany A Simone et al. Future Oncology
- New Research With Diets and Epilepsy
- (2013) J. Helen Cross JOURNAL OF CHILD NEUROLOGY
- Ketogenic Diets and Pain
- (2013) Susan A. Masino et al. JOURNAL OF CHILD NEUROLOGY
- HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
- (2013) Gregg L. Semenza JOURNAL OF CLINICAL INVESTIGATION
- Tumor-Derived Lactate Modifies Antitumor Immune Response: Effect on Myeloid-Derived Suppressor Cells and NK Cells
- (2013) Z. Husain et al. JOURNAL OF IMMUNOLOGY
- Health-related quality of life of significant others of patients with malignant CNS versus non-CNS tumors: a comparative study
- (2013) Florien W. Boele et al. JOURNAL OF NEURO-ONCOLOGY
- Caloric restriction reduces edema and prolongs survival in a mouse glioma model
- (2013) Yong-Sheng Jiang et al. JOURNAL OF NEURO-ONCOLOGY
- Nutrient Restriction and Radiation Therapy for Cancer Treatment: When Less Is More
- (2013) C. E. Champ et al. ONCOLOGIST
- The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer
- (2013) Angela M. Poff et al. PLoS One
- Hypoxia induces a phase transition within a kinase signaling network in cancer cells
- (2013) W. Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Optimization of Tumor Radiotherapy With Modulators of Cell Metabolism: Toward Clinical Applications
- (2013) Pierre Danhier et al. SEMINARS IN RADIATION ONCOLOGY
- Ketone bodies as signaling metabolites
- (2013) John C. Newman et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The evolution of genome-scale models of cancer metabolism
- (2013) Nathan E. Lewis et al. Frontiers in Physiology
- The “go or grow” potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress
- (2012) Elisabeth Höring et al. ACTA NEUROPATHOLOGICA
- Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer
- (2012) Howard S. Kim et al. BJU INTERNATIONAL
- Metabolic Reprogramming: A Cancer Hallmark Even Warburg Did Not Anticipate
- (2012) Patrick S. Ward et al. CANCER CELL
- c-Myc and Cancer Metabolism
- (2012) D. M. Miller et al. CLINICAL CANCER RESEARCH
- Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications
- (2012) Liuqi Yang et al. EXPERIMENTAL CELL RESEARCH
- Function of carbonic anhydrase IX in glioblastoma multiforme
- (2012) M. A. Proescholdt et al. NEURO-ONCOLOGY
- A ketone ester diet exhibits anxiolytic and cognition-sparing properties, and lessens amyloid and tau pathologies in a mouse model of Alzheimer's disease
- (2012) Yoshihiro Kashiwaya et al. NEUROBIOLOGY OF AGING
- The Ketogenic Diet Is an Effective Adjuvant to Radiation Therapy for the Treatment of Malignant Glioma
- (2012) Mohammed G. Abdelwahab et al. PLoS One
- Inflammation-Mediated Memory Dysfunction and Effects of a Ketogenic Diet in a Murine Model of Multiple Sclerosis
- (2012) Do Young Kim et al. PLoS One
- Fasting Enhances the Response of Glioma to Chemo- and Radiotherapy
- (2012) Fernando Safdie et al. PLoS One
- The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model
- (2012) Jorge Caso et al. PROSTATE
- Suppression of Oxidative Stress by -Hydroxybutyrate, an Endogenous Histone Deacetylase Inhibitor
- (2012) T. Shimazu et al. SCIENCE
- Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy
- (2012) C. Lee et al. Science Translational Medicine
- Cancer Cell Metabolism: One Hallmark, Many Faces
- (2012) Jason R. Cantor et al. Cancer Discovery
- Differential utilization of ketone bodies by neurons and glioma cell lines: a rationale for ketogenic diet as experimental glioma therapy
- (2011) Gabriele D Maurer et al. BMC CANCER
- Abstract 638: Mechanistic studies of the ketogenic diet as an adjuvant therapy for malignant gliomas
- (2011) Adrienne C. Scheck et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Metabolism and brain cancer
- (2011) Suely Kazue Nagahashi Marie et al. Clinics
- The ketogenic diet for the treatment of glioma: Insights from genetic profiling
- (2011) Adrienne C. Scheck et al. EPILEPSY RESEARCH
- Neuroprotection in metabolism-based therapy
- (2011) Adam L. Hartman EPILEPSY RESEARCH
- Modulation of oxidative stress and mitochondrial function by the ketogenic diet
- (2011) Julie Milder et al. EPILEPSY RESEARCH
- The powerful applications of polyunsaturated fatty acids in improving the therapeutic efficacy of anticancer drugs
- (2011) Jianhong Wang et al. Expert Opinion on Drug Delivery
- Response assessment in neuro-oncology (a report of the RANO group): assessment of outcome in trials of diffuse low-grade gliomas
- (2011) MJ van den Bent et al. LANCET ONCOLOGY
- Reductive glutamine metabolism by IDH1 mediates lipogenesis under hypoxia
- (2011) Christian M. Metallo et al. NATURE
- Bevacizumab impairs oxidative energy metabolism and shows antitumoral effects in recurrent glioblastomas: a 31P/1H MRSI and quantitative magnetic resonance imaging study
- (2011) E. Hattingen et al. NEURO-ONCOLOGY
- Effects of a ketogenic diet on the quality of life in 16 patients with advanced cancer: A pilot trial
- (2011) Melanie Schmidt et al. Nutrition & Metabolism
- Molecular Heterogeneity in Glioblastoma: Therapeutic Opportunities and Challenges
- (2011) M. Kelly Nicholas et al. SEMINARS IN ONCOLOGY
- Calorie Restriction as an Anti-Invasive Therapy for Malignant Brain Cancer in the VM Mouse
- (2010) Laura M Shelton et al. ASN Neuro
- Metabolic management of brain cancer
- (2010) Thomas N. Seyfried et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Reduced Levels of IGF-I Mediate Differential Protection of Normal and Cancer Cells in Response to Fasting and Improve Chemotherapeutic Index
- (2010) C. Lee et al. CANCER RESEARCH
- Fasting and differential chemotherapy protection in patients
- (2010) Lizzia Raffaghello et al. CELL CYCLE
- Current and emerging molecular targets in glioma
- (2010) Rafael Roesler et al. Expert Review of Anticancer Therapy
- AQP-4 in peritumoral edematous tissue is correlated with the degree of glioma and with expression of VEGF and HIF-alpha
- (2010) Kejie Mou et al. JOURNAL OF NEURO-ONCOLOGY
- Metabolic management of glioblastoma multiforme using standard therapy together with a restricted ketogenic diet: Case Report
- (2010) Giulio Zuccoli et al. Nutrition & Metabolism
- The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma
- (2010) Phillip Stafford et al. Nutrition & Metabolism
- Therapeutic options for recurrent malignant glioma
- (2010) Maximilian Niyazi et al. RADIOTHERAPY AND ONCOLOGY
- The Effects of Varying Dietary Carbohydrate and Fat Content on Survival in a Murine LNCaP Prostate Cancer Xenograft Model
- (2009) J. C. Mavropoulos et al. Cancer Prevention Research
- Glioblastoma Cells Require Glutamate Dehydrogenase to Survive Impairments of Glucose Metabolism or Akt Signaling
- (2009) C. Yang et al. CANCER RESEARCH
- Hypoxia Helps Glioma to Fight Therapy
- (2009) Verena Amberger-Murphy CURRENT CANCER DRUG TARGETS
- The ketogenic diet and epilepsy
- (2009) Do Young Kim et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Availability of neurotransmitter glutamate is diminished when β-hydroxybutyrate replaces glucose in cultured neurons
- (2009) Trine M Lund et al. JOURNAL OF NEUROCHEMISTRY
- Ketone bodies inhibit the viability of human neuroblastoma cells
- (2009) Robert Skinner et al. JOURNAL OF PEDIATRIC SURGERY
- Relationships between Cycling Hypoxia, HIF-1, Angiogenesis and Oxidative Stress
- (2009) Mark W. Dewhirst RADIATION RESEARCH
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Growth of human gastric cancer cells in nude mice is delayed by a ketogenic diet supplemented with omega-3 fatty acids and medium-chain triglycerides
- (2008) Christoph Otto et al. BMC CANCER
- The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies
- (2008) Marwan Maalouf et al. BRAIN RESEARCH REVIEWS
- Ketones and brain function: Possible link to polyunsaturated fatty acids and availability of a new brain PET tracer,11C-acetoacetate
- (2008) Fabien Pifferi et al. EPILEPSIA
- Neuroprotection in Diet-Induced Ketotic Rat Brain after Focal Ischemia
- (2008) Michelle A Puchowicz et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet
- (2008) Jeremy Marsh et al. Nutrition & Metabolism
- Starvation-dependent differential stress resistance protects normal but not cancer cells against high-dose chemotherapy
- (2008) L. Raffaghello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Homeostatic functions of the p53 tumor suppressor: Regulation of energy metabolism and antioxidant defense
- (2008) Ivan A. Olovnikov et al. SEMINARS IN CANCER BIOLOGY
- Is Akt the “Warburg kinase”?—Akt-energy metabolism interactions and oncogenesis
- (2008) R. Brooks Robey et al. SEMINARS IN CANCER BIOLOGY
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