Structural and dynamic evolution of the amphipathic N-terminus diversifies enzyme thermostability in the glycoside hydrolase family 12

Signatures of protein thermal denaturation and local hydrophobicity in domain specific hydration behavior: a comparative molecular dynamics study

(2016) Prathit Chatterjee et al.   Molecular BioSystems

Ligand-binding specificity and promiscuity of the main lignocellulolytic enzyme families as revealed by active-site architecture analysis

(2016) Li Tian et al.   Scientific Reports

Substrate-binding specificity of chitinase and chitosanase as revealed by active-site architecture analysis

(2015) Shijia Liu et al.   CARBOHYDRATE RESEARCH

Rigidity versus flexibility: the dilemma of understanding protein thermal stability

(2015) Andrey Karshikoff et al.   FEBS Journal

Enzymatic hydrolysis of lignocellulosic polysaccharides in the presence of ionic liquids

(2015) R. M. Wahlström et al.   GREEN CHEMISTRY

Improvement of Trichoderma reesei xylanase II thermal stability by serine to threonine surface mutations

(2015) Dorra Zouari Ayadi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Insights into the unfolding pathway and identification of thermally sensitive regions of phytase from Aspergillus niger by molecular dynamics simulations

(2015) Kapil Kumar et al.   JOURNAL OF MOLECULAR MODELING

Subsite-specific contributions of different aromatic residues in the active site architecture of glycoside hydrolase family 12

(2015) Xiaomei Zhang et al.   Scientific Reports

Engineered thermostable fungal cellulases exhibit efficient synergistic cellulose hydrolysis at elevated temperatures

(2014) Devin L. Trudeau et al.   BIOTECHNOLOGY AND BIOENGINEERING

A combined cell-consortium approach for lignocellulose degradation by specialized Lactobacillus plantarum cells

(2014) Sarah Moraïs et al.   Biotechnology for Biofuels

Protein engineering of cellulases

(2014) Andreas S Bommarius et al.   CURRENT OPINION IN BIOTECHNOLOGY

Improving Trichoderma reesei Cel7B Thermostability by Targeting the Weak Spots

(2014) Shujun Zhang et al.   Journal of Chemical Information and Modeling

The non-uniform early structural response of globular proteins to cold denaturing conditions: A case study with Yfh1

(2014) Prathit Chatterjee et al.   JOURNAL OF CHEMICAL PHYSICS

Cellulosic ethanol at last?

(2014) R. F. Service   SCIENCE

Investigating the Impact of Asp181 Point Mutations on Interactions between PTP1B and Phosphotyrosine Substrate

(2014) Mengyuan Liu et al.   Scientific Reports

Improving the Thermostability and Catalytic Efficiency of Bacillus deramificans Pullulanase by Site-Directed Mutagenesis

(2013) Xuguo Duan et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

(2013) Sander Pronk et al.   BIOINFORMATICS

Engineered thermostable fungal Cel6A and Cel7A cellobiohydrolases hydrolyze cellulose efficiently at elevated temperatures

(2013) Indira Wu et al.   BIOTECHNOLOGY AND BIOENGINEERING

Computational Investigation of the pH Dependence of Loop Flexibility and Catalytic Function in Glycoside Hydrolases

(2013) Lintao Bu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative molecular dynamics simulation studies for determining factors contributing to the thermostability of chemotaxis protein “CheY”

(2013) Manish Paul et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

UNDERSTANDING THE MOLECULAR MECHANISM OF BINDING MODES OF AURORA A INHIBITORS BY LONG TIME SCALE GPU DYNAMICS

(2013) TING FU et al.   JOURNAL OF THEORETICAL & COMPUTATIONAL CHEMISTRY

The carbohydrate-active enzymes database (CAZy) in 2013

(2013) Vincent Lombard et al.   NUCLEIC ACIDS RESEARCH

Battle for the Barrel

(2013) R. F. Service   SCIENCE

Improved thermal performance of Thermomyces lanuginosus GH11 xylanase by engineering of an N-terminal disulfide bridge

(2012) Yawei Wang et al.   BIORESOURCE TECHNOLOGY

Engineering the third wave of biocatalysis

(2012) U. T. Bornscheuer et al.   NATURE

Enhanced activity of Thermotoga maritima cellulase 12A by mutating a unique surface loop

(2011) Ya-Shan Cheng et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Development of thermostable Candida antarctica lipase B through novel in silico design of disulfide bridge

(2011) Quang Anh Tuan Le et al.   BIOTECHNOLOGY AND BIOENGINEERING

Study and design of stability in GH5 cellulases

(2011) Somayesadat Badieyan et al.   BIOTECHNOLOGY AND BIOENGINEERING

Optimization of parameters for molecular dynamics simulation using smooth particle-mesh Ewald in GROMACS 4.5

(2011) Mark J. Abraham et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods

(2011) K. Tamura et al.   MOLECULAR BIOLOGY AND EVOLUTION

Five mutations in N-terminus confer thermostability on mesophilic xylanase

(2010) Shan Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein stability, flexibility and function

(2010) Kaare Teilum et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Increasing cellulose accessibility is more important than removing lignin: A comparison of cellulose solvent-based lignocellulose fractionation and soaking in aqueous ammonia

(2010) Joseph A. Rollin et al.   BIOTECHNOLOGY AND BIOENGINEERING

Enhanced Stability of a Protein with Increasing Temperature

(2010) Joachim M. Vinther et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An additional aromatic interaction improves the thermostability and thermophilicity of a mesophilic family 11 xylanase: Structural basis and molecular study

(2010) Jacques Georis et al.   PROTEIN SCIENCE

Atomic-Level Characterization of the Structural Dynamics of Proteins

(2010) D. E. Shaw et al.   SCIENCE

Dynameomics: A Consensus View of the Protein Unfolding/Folding Transition State Ensemble across a Diverse Set of Protein Folds

(2009) Amanda L. Jonsson et al.   BIOPHYSICAL JOURNAL

Assessing computational methods for predicting protein stability upon mutation: good on average but not in the details

(2009) V. Potapov et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Replacement of the active surface of a thermophile protein by that of a homologous mesophile protein through structure-guided ‘protein surface grafting’

(2008) Divya Kapoor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Engineering Hyperthermostability into a GH11 Xylanase Is Mediated by Subtle Changes to Protein Structure

(2008) Claire Dumon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Temperature-induced unfolding pathway of a type III antifreeze protein: Insight from molecular dynamics simulation

(2008) Sangeeta Kundu et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

The Complex Inter-Relationships Between Protein Flexibility and Stability

(2008) Tim J. Kamerzell et al.   JOURNAL OF PHARMACEUTICAL SCIENCES