Autophagy in acute brain injury

Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury

(2016) Cuicui Xie et al.   Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin

(2016) Cinzia Fabrizi et al.   NEUROTOXICOLOGY

Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade

(2016) Prasun Guha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy Inhibitor 3-MA Weakens Neuroprotective Effects of Posttraumatic Brain Injury Moderate Hypothermia

(2016) Yichao Jin et al.   World Neurosurgery

Hormesis, cell death and aging

(2016) Isabelle Martins et al.   Aging-US

Mechanisms of Autophagy

(2015) Nobuo N. Noda et al.   Annual Review of Biophysics

Antiretrovirals, Methamphetamine, and HIV-1 Envelope Protein gp120 Compromise Neuronal Energy Homeostasis in Association with Various Degrees of Synaptic and Neuritic Damage

(2015) Ana B. Sanchez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Cocaine-mediated microglial activation involves the ER stress-autophagy axis

(2015) Ming-Lei Guo et al.   Autophagy

Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation

(2015) Ling-Yan Su et al.   Autophagy

VEGF inhibits the inflammation in spinal cord injury through activation of autophagy

(2015) Hongyu Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Low Dose Administration of Glutamate Triggers a Non-Apoptotic, Autophagic Response in PC12 Cells

(2015) Eleni Stamoula et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Autophagy in malignant transformation and cancer progression

(2015) L. Galluzzi et al.   EMBO JOURNAL

Chaperone-Mediated Autophagy after Traumatic Brain Injury

(2015) Yujung Park et al.   JOURNAL OF NEUROTRAUMA

Sestrin2 Protects Dopaminergic Cells against Rotenone Toxicity through AMPK-Dependent Autophagy Activation

(2015) Yi-Sheng Hou et al.   MOLECULAR AND CELLULAR BIOLOGY

Rapamycin increases neuronal survival, reduces inflammation and astrocyte proliferation after spinal cord injury

(2015) Yona Goldshmit et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Organelle-Specific Initiation of Autophagy

(2015) Valentina Sica et al.   MOLECULAR CELL

Coordination of mitophagy and mitochondrial biogenesis during ageing in C. elegans

(2015) Konstantinos Palikaras et al.   NATURE

Autophagy at the crossroads of catabolism and anabolism

(2015) Jasvinder Kaur et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Compromised autophagy and neurodegenerative diseases

(2015) Fiona M. Menzies et al.   NATURE REVIEWS NEUROSCIENCE

Glutamate excitotoxicity in neurons triggers mitochondrial and endoplasmic reticulum accumulation of Parkin, and, in the presence of N-acetyl cysteine, mitophagy

(2015) Victor S. Van Laar et al.   NEUROBIOLOGY OF DISEASE

Retinoic Acid Prevents Disruption of Blood-Spinal Cord Barrier by Inducing Autophagic Flux After Spinal Cord Injury

(2015) Yulong Zhou et al.   NEUROCHEMICAL RESEARCH

Melatonin protects the brain from apoptosis by enhancement of autophagy after traumatic brain injury in mice

(2015) Ke Ding et al.   NEUROCHEMISTRY INTERNATIONAL

Essential role of D1R in the regulation of mTOR complex1 signaling induced by cocaine

(2015) Laurie P. Sutton et al.   NEUROPHARMACOLOGY

Neonatal anoxia in rats: Hippocampal cellular and subcellular changes related to cell death and spatial memory

(2015) S.H. Takada et al.   NEUROSCIENCE

17AAG improves histological and functional outcomes in a rat CCI model through autophagy activation and apoptosis attenuation

(2015) Lixin Ma et al.   NEUROSCIENCE LETTERS

Autophagy Inhibition by Caffeine Increases Toxicity of Methamphetamine in SH-SY5Y Neuroblastoma Cell Line

(2015) Rujiraporn Pitaksalee et al.   NEUROTOXICITY RESEARCH

GAPDH-knockdown reduce rotenone-induced H9C2 cells death via autophagy and anti-oxidative stress pathway

(2015) Shao Liang et al.   TOXICOLOGY LETTERS

Priming the Inflammatory Pump of the CNS after Traumatic Brain Injury

(2015) Kristina G. Witcher et al.   TRENDS IN NEUROSCIENCES

Disrupted autophagy after spinal cord injury is associated with ER stress and neuronal cell death

(2015) S Liu et al.   Cell Death & Disease

Stimulation of autophagy promotes functional recovery in diabetic rats with spinal cord injury

(2015) Kai-liang Zhou et al.   Scientific Reports

Autophagy in neonatal hypoxia ischemic brain is associated with oxidative stress

(2015) Qing Lu et al.   Redox Biology

Autophagy inhibition uncovers the neurotoxic action of the antipsychotic drug olanzapine

(2015) Ljubica Vucicevic et al.   Autophagy

Autophagy Activation Is Involved in 3,4-Methylenedioxymethamphetamine (‘Ecstasy’)—Induced Neurotoxicity in Cultured Cortical Neurons

(2015) I-Hsun Li et al.   PLoS One

The Effects of Methylene Blue on Autophagy and Apoptosis in MRI-Defined Normal Tissue, Ischemic Penumbra and Ischemic Core

(2015) Zhao Jiang et al.   PLoS One

Dying neurons in thalamus of asphyxiated term newborns and rats are autophagic

(2014) Vanessa Ginet et al.   ANNALS OF NEUROLOGY

Beclin-1-mediated autophagy protects spinal cord neurons against mechanical injury-induced apoptosis

(2014) Zhen-Yu Wang et al.   APOPTOSIS

Autophagy is increased in mice after traumatic brain injury and is detectable in human brain after trauma and critical illness

(2014) Robert S.B. Clark et al.   Autophagy

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

(2014) Yan Wang et al.   Autophagy

Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways

(2014) Ya-Dan Wen et al.   Autophagy

Involvement of autophagy in hypoxic-excitotoxic neuronal death

(2014) Vanessa Ginet et al.   Autophagy

Impaired autophagy flux is associated with neuronal cell death after traumatic brain injury

(2014) Chinmoy Sarkar et al.   Autophagy

Endoplasmic reticulum stress induced by tunicamycin and thapsigargin protects against transient ischemic brain injury

(2014) Xiangnan Zhang et al.   Autophagy

ARRB1/β-arrestin-1 mediates neuroprotection through coordination of BECN1-dependent autophagy in cerebral ischemia

(2014) Pei Wang et al.   Autophagy

Posttraumatic administration of luteolin protects mice from traumatic brain injury: Implication of autophagy and inflammation

(2014) Jianguo Xu et al.   BRAIN RESEARCH

Ischemic preconditioning enhances autophagy but suppresses autophagic cell death in rat spinal neurons following ischemia-reperfusion

(2014) Jin Fan et al.   BRAIN RESEARCH

Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre-activation of AMPK-dependent autophagy

(2014) Teng Jiang et al.   BRITISH JOURNAL OF PHARMACOLOGY

2-Methoxyestradiol Attenuates Autophagy Activation After Global Ischemia

(2014) Xiao-Yu Xin et al.   CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES

Metabolic Control of Autophagy

(2014) Lorenzo Galluzzi et al.   CELL

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

BNIP3 Interacting with LC3 Triggers Excessive Mitophagy in Delayed Neuronal Death in Stroke

(2014) Ruo-Yang Shi et al.   CNS Neuroscience & Therapeutics

Mfn2 downregulation in excitotoxicity causes mitochondrial dysfunction and delayed neuronal death

(2014) A. Martorell-Riera et al.   EMBO JOURNAL

Glycogen accumulation underlies neurodegeneration and autophagy impairment in Lafora disease

(2014) J. Duran et al.   HUMAN MOLECULAR GENETICS

Preconditioning Stimuli Induce Autophagy via Sphingosine Kinase 2 in Mouse Cortical Neurons

(2014) Rui Sheng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MFN2 Couples Glutamate Excitotoxicity and Mitochondrial Dysfunction in Motor Neurons

(2014) Wenzhang Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

IGF-1 Alleviates NMDA-Induced Excitotoxicity in Cultured Hippocampal Neurons Against Autophagy via the NR2B/PI3K-AKT-mTOR Pathway

(2014) Yansong Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The role of autophagy in epileptogenesis and in epilepsy-induced neuronal alterations

(2014) Filippo Sean Giorgi et al.   JOURNAL OF NEURAL TRANSMISSION

N-Acetyl-Serotonin Offers Neuroprotection through Inhibiting Mitochondrial Death Pathways and Autophagic Activation in Experimental Models of Ischemic Injury

(2014) H. Zhou et al.   JOURNAL OF NEUROSCIENCE

Inhibition of Autophagy Contributes to Melatonin-Mediated Neuroprotection Against Transient Focal Cerebral Ischemia in Rats

(2014) Yongqiu Zheng et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Ischemic Preconditioning Provides Neuroprotection by Induction of AMP-Activated Protein Kinase-Dependent Autophagy in a Rat Model of Ischemic Stroke

(2014) Teng Jiang et al.   MOLECULAR NEUROBIOLOGY

Enhancement of Autophagy by Histone Deacetylase Inhibitor Trichostatin A Ameliorates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats

(2014) Anwen Shao et al.   MOLECULAR NEUROBIOLOGY

Pinocembrin Protects the Brain against Ischemia-Reperfusion Injury and Reverses the Autophagy Dysfunction in the Penumbra Area

(2014) Gang Zhao et al.   MOLECULES

Organelle-specific initiation of cell death

(2014) Lorenzo Galluzzi et al.   NATURE CELL BIOLOGY

Caloric restriction mimetics: towards a molecular definition

(2014) Frank Madeo et al.   NATURE REVIEWS DRUG DISCOVERY

Self-consumption: the interplay of autophagy and apoptosis

(2014) Guillermo Mariño et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Neuroprotective effects of mesenchymal stem cells through autophagy modulation in a parkinsonian model

(2014) Hyun Jung Park et al.   NEUROBIOLOGY OF AGING

Autophagy Activation Contributes to the Neuroprotection of Remote Ischemic Perconditioning Against Focal Cerebral Ischemia in Rats

(2014) Jingyuan Su et al.   NEUROCHEMICAL RESEARCH

Apelin-13 Attenuates Traumatic Brain Injury-Induced Damage by Suppressing Autophagy

(2014) Hai-Jun Bao et al.   NEUROCHEMICAL RESEARCH

Neuroprotective Effects of Autophagy Induced by Rapamycin in Rat Acute Spinal Cord Injury Model

(2014) Zhen-Yu Wang et al.   NEUROIMMUNOMODULATION

Hydrogen Sulfide Offers Neuroprotection on Traumatic Brain Injury in Parallel with Reduced Apoptosis and Autophagy in Mice

(2014) Mingyang Zhang et al.   PLoS One

Protection of Pyruvate against Glutamate Excitotoxicity Is Mediated by Regulating DAPK1 Protein Complex

(2014) Jingwei Tian et al.   PLoS One

Modulation of Mitochondrial Function and Autophagy Mediates Carnosine Neuroprotection Against Ischemic Brain Damage

(2014) Seung-Hoon Baek et al.   STROKE

TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain

(2014) A Pla et al.   Cell Death & Disease

Methamphetamine induces autophagy as a pro-survival response against apoptotic endothelial cell death through the Kappa opioid receptor

(2014) J Ma et al.   Cell Death & Disease

The endoplasmic reticulum stress inhibitor salubrinal inhibits the activation of autophagy and neuroprotection induced by brain ischemic preconditioning

(2013) Bo Gao et al.   ACTA PHARMACOLOGICA SINICA

Cerebral ischemia-reperfusion-induced autophagy protects against neuronal injury by mitochondrial clearance

(2013) Xiangnan Zhang et al.   Autophagy

Excitotoxic glutamate insults block autophagic flux in hippocampal neurons

(2013) Jacqueline R. Kulbe et al.   BRAIN RESEARCH

Differential Regulation of Distinct Vps34 Complexes by AMPK in Nutrient Stress and Autophagy

(2013) Joungmok Kim et al.   CELL

Chaperone-mediated autophagy: roles in disease and aging

(2013) Ana Maria Cuervo et al.   CELL RESEARCH

14-3-3 Proteins in the Regulation of Rotenone-Induced Neurotoxicity Might be via Its Isoform 14-3-3Epsilon’s Involvement in Autophagy

(2013) Yan Sai et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Non-autophagic roles of autophagy-related proteins

(2013) Suresh Subramani et al.   EMBO REPORTS

Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage

(2013) Jingyin Chen et al.   JOURNAL OF PINEAL RESEARCH

ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase

(2013) Ryan C. Russell et al.   NATURE CELL BIOLOGY

Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy

(2013) Michalis Papadakis et al.   NATURE MEDICINE

The autophagosome: origins unknown, biogenesis complex

(2013) Christopher A. Lamb et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

1-Methyl-4-Phenylpyridinium-Induced Cell Death via Autophagy Through a Bcl-2/Beclin 1 Complex-Dependent Pathway

(2013) Chutikorn Nopparat et al.   NEUROCHEMICAL RESEARCH

Neuroprotective effect of ceftriaxone in a rat model of traumatic brain injury

(2013) Changmeng Cui et al.   NEUROLOGICAL SCIENCES

The regulatory role of NF-κB in autophagy-like cell death after focal cerebral ischemia in mice

(2013) W.-L. Li et al.   NEUROSCIENCE

Propofol prevents cerebral ischemia-triggered autophagy activation and cell death in the rat hippocampus through the NF-κB/p53 signaling pathway

(2013) D.R. Cui et al.   NEUROSCIENCE

Hypoxic Preconditioning Alleviates Ethanol Neurotoxicity: The Involvement of Autophagy

(2013) Haiping Wang et al.   NEUROTOXICITY RESEARCH

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Knocking Down HMGB1 Using Dendrimer-Delivered siRNA Unveils Its Key Role in NMDA-Induced Autophagy in Rat Cortical Neurons

(2013) María D. Pérez-Carrión et al.   PHARMACEUTICAL RESEARCH

Autosis is a Na+,K+-ATPase-regulated form of cell death triggered by autophagy-inducing peptides, starvation, and hypoxia-ischemia

(2013) Y. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immunogenic Cell Death in Cancer Therapy

(2012) Guido Kroemer et al.   Annual Review of Immunology

Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia

(2012) Pei Wang et al.   Autophagy

Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage

(2012) Maria Teresa Viscomi et al.   Autophagy

Autophagy is a protective response to ethanol neurotoxicity

(2012) Gang Chen et al.   Autophagy

Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning

(2012) Rui Sheng et al.   Autophagy

Excessive Autophagy Contributes to Neuron Death in Cerebral Ischemia

(2012) Ruoyang Shi et al.   CNS Neuroscience & Therapeutics

Beta-asarone attenuates ischemia–reperfusion-induced autophagy in rat brains via modulating JNK, p-JNK, Bcl-2 and Beclin 1

(2012) Lin Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Excitotoxicity: Bridge to various triggers in neurodegenerative disorders

(2012) Ankita Mehta et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Therapeutic Effects of Valproate Combined With Lithium Carbonate on MPTP-Induced Parkinsonism in Mice: Possible Mediation Through Enhanced Autophagy

(2012) Xue-zhong Li et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures

(2012) C. Fabrizi et al.   JOURNAL OF NEURAL TRANSMISSION

Impaired Autophagy in Neurons after Disinhibition of Mammalian Target of Rapamycin and Its Contribution to Epileptogenesis

(2012) J. McMahon et al.   JOURNAL OF NEUROSCIENCE

Role of autophagy in early brain injury after subarachnoid hemorrhage in rats

(2012) Hongbo Zhao et al.   MOLECULAR BIOLOGY REPORTS

Necrostatin-1 Suppresses Autophagy and Apoptosis in Mice Traumatic Brain Injury Model

(2012) Yao-Qi Wang et al.   NEUROCHEMICAL RESEARCH

Therapeutic Effects of Rapamycin on MPTP-Induced Parkinsonism in Mice

(2012) Kangyong Liu et al.   NEUROCHEMICAL RESEARCH

Hypoxic stress activates chaperone-mediated autophagy and modulates neuronal cell survival

(2012) Eisuke Dohi et al.   NEUROCHEMISTRY INTERNATIONAL

Excessive Activation of mTOR in Postnatally Generated Granule Cells Is Sufficient to Cause Epilepsy

(2012) Raymund Y.K. Pun et al.   NEURON

Methamphetamine-induced neurotoxicity linked to ubiquitin-proteasome system dysfunction and autophagy-related changes that can be modulated by protein kinase C delta in dopaminergic neuronal cells

(2012) M. Lin et al.   NEUROSCIENCE

Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid hemorrhage

(2012) C.-h. Jing et al.   NEUROSCIENCE

p53 Mediates autophagy activation and mitochondria dysfunction in kainic acid-induced excitotoxicity in primary striatal neurons

(2012) X.X. Dong et al.   NEUROSCIENCE

NAD+ administration decreases ischemic brain damage partially by blocking autophagy in a mouse model of brain ischemia

(2012) Chaobo Zheng et al.   NEUROSCIENCE LETTERS

Akt-Mediated Regulation of Autophagy and Tumorigenesis Through Beclin 1 Phosphorylation

(2012) R. C. Wang et al.   SCIENCE

Cardiac Glycosides Exert Anticancer Effects by Inducing Immunogenic Cell Death

(2012) L. Menger et al.   Science Translational Medicine

Taurine attenuates methamphetamine-induced autophagy and apoptosis in PC12 cells through mTOR signaling pathway

(2012) Yan Li et al.   TOXICOLOGY LETTERS

Nicotinamide phosphoribosyltransferase protects against ischemic stroke through SIRT1-dependent adenosine monophosphate-activated kinase pathway

(2011) Pei Wang et al.   ANNALS OF NEUROLOGY

GSK-3β inhibitors suppressed neuroinflammation in rat cortex by activating autophagy in ischemic brain injury

(2011) Xiaogang Zhou et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

In vivo optical imaging for evaluating the efficacy of edaravone after transient cerebral ischemia in mice

(2011) Ning Liu et al.   BRAIN RESEARCH

Autophagy activation is involved in neuroprotection induced by hyperbaric oxygen preconditioning against focal cerebral ischemia in rats

(2011) Wenjun Yan et al.   BRAIN RESEARCH

Microautophagy: lesser-known self-eating

(2011) Wen-wen Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Transmembrane protein 166 regulates autophagic and apoptotic activities following focal cerebral ischemic injury in rats

(2011) Li Li et al.   EXPERIMENTAL NEUROLOGY

Lithium-Mediated Long-Term Neuroprotection in Neonatal Rat Hypoxia–Ischemia is Associated with Antiinflammatory Effects and Enhanced Proliferation and Survival of Neural Stem/Progenitor Cells

(2011) Hongfu Li et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Dendrimer-mediated siRNA delivery knocks down Beclin 1 and potentiates NMDA-mediated toxicity in rat cortical neurons

(2011) María D. Pérez-Carrión et al.   JOURNAL OF NEUROCHEMISTRY

Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation

(2011) Chia-Fu Chang et al.   JOURNAL OF PINEAL RESEARCH

The role of antimalarial agents in the treatment of SLE and lupus nephritis

(2011) Senq-J Lee et al.   Nature Reviews Nephrology

Autophagy is involved in traumatic brain injury-induced cell death and contributes to functional outcome deficits in mice

(2011) C.-L. Luo et al.   NEUROSCIENCE

Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation

(2011) S. Carloni et al.   NEUROSCIENCE

Caffeine potentiates methamphetamine-induced toxicity both in vitro and in vivo

(2011) Theerin Sinchai et al.   NEUROSCIENCE LETTERS

Sphingosine Kinase 2 Mediates Cerebral Preconditioning and Protects the Mouse Brain Against Ischemic Injury

(2011) Lai Ming Yung et al.   STROKE

Autophagy was activated in injured astrocytes and mildly decreased cell survival following glucose and oxygen deprivation and focal cerebral ischemia

(2010) Ai-Ping Qin et al.   Autophagy

Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia

(2010) Silvia Carloni et al.   Autophagy

p62/SQSTM1 is required for Parkin-induced mitochondrial clustering but not mitophagy; VDAC1 is dispensable for both

(2010) Derek Narendra et al.   Autophagy

Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning

(2010) Rui Sheng et al.   Autophagy

Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype

(2010) Shankar Sadasivan et al.   BMC NEUROSCIENCE

The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress

(2010) T.-S. Kim et al.   Disease Models & Mechanisms

Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of Tuberous Sclerosis Complex

(2010) L.-H. Zeng et al.   HUMAN MOLECULAR GENETICS

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

Antiapoptotic and antiautophagic effects of glial cell line-derived neurotrophic factor and hepatocyte growth factor after transient middle cerebral artery occlusion in rats

(2010) Jingwei Shang et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy

(2010) Chutikorn Nopparat et al.   JOURNAL OF PINEAL RESEARCH

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Neuroprotection of kaempferol by autophagy in models of rotenone-mediated acute toxicity: possible implications for Parkinson's disease

(2010) Giuseppe Filomeni et al.   NEUROBIOLOGY OF AGING

Neuroprotection of deferoxamine on rotenone-induced injury via accumulation of HIF-1α and induction of autophagy in SH-SY5Y cells

(2010) Yuncheng Wu et al.   NEUROCHEMISTRY INTERNATIONAL

Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization

(2010) J. Wu et al.   NEUROSCIENCE

Parkinson's disease involves autophagy and abnormal distribution of cathepsin L

(2010) Lingyun Li et al.   NEUROSCIENCE LETTERS

ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS

(2010) A. Alexander et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

(2010) D. F. Egan et al.   SCIENCE

Lithium reduces apoptosis and autophagy after neonatal hypoxia–ischemia

(2010) Q Li et al.   Cell Death & Disease

Manganese Superoxide Dismutase Deficiency Exacerbates Ischemic Brain Damage Under Hyperglycemic Conditions by Altering Autophagy

(2010) Suresh L. Mehta et al.   Translational Stroke Research

RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats

(2009) Yong-qiu Zheng et al.   ACTA PHARMACOLOGICA SINICA

Enhancement of Autophagic Flux after Neonatal Cerebral Hypoxia-Ischemia and Its Region-Specific Relationship to Apoptotic Mechanisms

(2009) Vanessa Ginet et al.   AMERICAN JOURNAL OF PATHOLOGY

Postischemic treatment of neonatal cerebral ischemia should target autophagy

(2009) Julien Puyal et al.   ANNALS OF NEUROLOGY

Role of Autophagy during Methamphetamine Neurotoxicity

(2009) Livia Pasquali et al.   Annals of the New York Academy of Sciences

DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy

(2009) Einat Zalckvar et al.   EMBO REPORTS

p53 induction contributes to excitotoxic neuronal death in rat striatum through apoptotic and autophagic mechanisms

(2009) Yan Wang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Constitutive Reactive Oxygen Species Generation from Autophagosome/Lysosome in Neuronal Oxidative Toxicity

(2009) Chisato Kubota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Silencing DJ-1 reveals its contribution in paraquat-induced autophagy

(2009) Rosa A. González-Polo et al.   JOURNAL OF NEUROCHEMISTRY

Pharmacological Inhibition of mTORC1 Suppresses Anatomical, Cellular, and Behavioral Abnormalities in Neural-Specific Pten Knock-Out Mice

(2009) J. Zhou et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial membrane permeabilization in neuronal injury

(2009) Lorenzo Galluzzi et al.   NATURE REVIEWS NEUROSCIENCE

Rapamycin protects against rotenone-induced apoptosis through autophagy induction

(2009) T. Pan et al.   NEUROSCIENCE

Lithium prevents excitotoxic cell death of motoneurons in organotypic slice cultures of spinal cord

(2009) J. Calderó et al.   NEUROSCIENCE

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic Injury

(2008) Masato Koike et al.   AMERICAN JOURNAL OF PATHOLOGY

Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex

(2008) Ling-Hui Zeng et al.   ANNALS OF NEUROLOGY

Suppression of autophagy precipitates neuronal cell death following low doses of methamphetamine

(2008) Roberta Castino et al.   JOURNAL OF NEUROCHEMISTRY

Autophagic cell death: the story of a misnomer

(2008) Guido Kroemer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury

(2008) Silvia Carloni et al.   NEUROBIOLOGY OF DISEASE

Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement

(2008) Tianhong Pan et al.   NEUROBIOLOGY OF DISEASE

Spinal cord injury induces upregulation of Beclin 1 and promotes autophagic cell death

(2008) Haruo Kanno et al.   NEUROBIOLOGY OF DISEASE