Melatonin attenuates kainic acid-induced neurotoxicity in mouse hippocampus via inhibition of autophagy and α-synuclein aggregation

Mitochondrial Dysfunction in Parkinson's Disease

(2017) Jianhui Zhu et al.   JOURNAL OF ALZHEIMERS DISEASE

An autophagic mechanism is involved in apoptotic death of rat striatal neurons induced by the non-N-methyl-D-aspartate receptor agonist kainic acid

(2014) Yan Wang et al.   Autophagy

Autophagic activity in cortical neurons under acute oxidative stress directly contributes to cell death

(2011) Gavin C. Higgins et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Melatonin as a natural ally against oxidative stress: a physicochemical examination

(2011) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Oxidative Stress and Energy Crises in Neuronal Dysfunction

(2010) David G. Nicholls   Annals of the New York Academy of Sciences

An overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders

(2010) Antoni Camins et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Role of autophagy in protection afforded by hypoxic preconditioning against MPP+-induced neurotoxicity in SH-SY5Y cells

(2010) Y.W. Tzeng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Melatonin protects N2a against ischemia/reperfusion injury through autophagy enhancement

(2010) Yanchun Guo et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Induction of the unfolded protein response by α-synuclein in experimental models of Parkinson’s disease

(2010) Arianna Bellucci et al.   JOURNAL OF NEUROCHEMISTRY

The mechanism for the neuroprotective effect of melatonin against methamphetamine-induced autophagy

(2010) Chutikorn Nopparat et al.   JOURNAL OF PINEAL RESEARCH

Melatonin, cardiolipin and mitochondrial bioenergetics in health and disease

(2010) Giuseppe Paradies et al.   JOURNAL OF PINEAL RESEARCH

Anti-inflammatory effects of pioglitazone on iron-induced oxidative injury in the nigrostriatal dopaminergic system

(2010) H. C. Yu et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Parkinson's disease involves autophagy and abnormal distribution of cathepsin L

(2010) Lingyun Li et al.   NEUROSCIENCE LETTERS

The Antiapoptotic Activity of Melatonin in Neurodegenerative Diseases

(2009) Xin Wang   CNS Neuroscience & Therapeutics

Enhanced α-Synuclein Expression in Human Neurodegenerative Diseases: Pathogenetic and Therapeutic Implications

(2009) Alison McCormack et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Stabilization of mitochondrial function by tetramethylpyrazine protects against kainate-induced oxidative lesions in the rat hippocampus

(2009) Shu-Yan Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Physiological and Pathological Role of Alpha-synuclein in Parkinson’s Disease Through Iron Mediated Oxidative Stress; The Role of a Putative Iron-responsive Element

(2009) David Olivares et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of ubiquitin linkages on α-synuclein induced-toxicity in aDrosophilamodel of Parkinson’s disease

(2009) Francesca K. M. Lee et al.   JOURNAL OF NEUROCHEMISTRY

Therapeutic potential of melatonin in traumatic central nervous system injury

(2009) Supriti Samantaray et al.   JOURNAL OF PINEAL RESEARCH

Autophagy–physiology and pathophysiology

(2008) Yasuo Uchiyama et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells

(2008) Tereza Vogiatzi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lysosomal enzyme cathepsin D protects against alpha-synuclein aggregation and toxicity

(2008) Liyan Qiao et al.   Molecular Brain