TLR4 mediates the impairment of ubiquitin-proteasome and autophagy-lysosome pathways induced by ethanol treatment in brain

Determining the Threshold for Alcohol-Induced Brain Damage: New Evidence with Gliosis Markers

(2013) Dayna M. Hayes et al.   ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH

Reactive glia show increased immunoproteasome activity in Alzheimer’s disease

(2013) Marie Orre et al.   BRAIN

The Role of Autophagy Dysregulation in Manganese-Induced Dopaminergic Neurodegeneration

(2013) Jianbin Zhang et al.   NEUROTOXICITY RESEARCH

Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome

(2012) John J. Graziotto et al.   Autophagy

Crosstalk between the ubiquitin–proteasome system and autophagy in a human cellular model of Alzheimer's disease

(2012) Valentina Cecarini et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Proteasome protease mediated regulation of cytokine induction and inflammation

(2012) Nilofer Qureshi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

The immunoproteasome in antigen processing and other immunological functions

(2012) Michael Basler et al.   CURRENT OPINION IN IMMUNOLOGY

Toll-like receptor 4 participates in the myelin disruptions associated with chronic alcohol abuse

(2012) Silvia Alfonso-Loeches et al.   GLIA

Lipopolysaccharide-induced neuroinflammation leads to the accumulation of ubiquitinated proteins and increases susceptibility to neurodegeneration induced by proteasome inhibition in rat hippocampus

(2012) Cristina Pintado et al.   Journal of Neuroinflammation

Defective Autophagy in Parkinson’s Disease: Role of Oxidative Stress

(2012) Elzbieta Janda et al.   MOLECULAR NEUROBIOLOGY

Bortezomib Combination Therapy in Multiple Myeloma

(2012) Prashant Kapoor et al.   SEMINARS IN HEMATOLOGY

Endoplasmic reticulum stress activates autophagy but not the proteasome in neuronal cells: implications for Alzheimer's disease

(2011) D A T Nijholt et al.   CELL DEATH AND DIFFERENTIATION

Immune and non-immune functions of the immunoproteasome

(2011) Arkhjamil Angeles   Frontiers in Bioscience-Landmark

Autophagy deregulation in neurodegenerative diseases - recent advances and future perspectives

(2011) Zelda H. Cheung et al.   JOURNAL OF NEUROCHEMISTRY

Role of AMPK-mTOR-Ulk1/2 in the Regulation of Autophagy: Cross Talk, Shortcuts, and Feedbacks

(2011) S. Alers et al.   MOLECULAR AND CELLULAR BIOLOGY

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

(2011) Joungmok Kim et al.   NATURE CELL BIOLOGY

Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: Implication for protein aggregation and immune response

(2011) Caterina Bendotti et al.   PROGRESS IN NEUROBIOLOGY

Involvement of autophagy in alcoholic liver injury and hepatitis C pathogenesis

(2011) Natalia A Osna   WORLD JOURNAL OF GASTROENTEROLOGY

mTOR Signaling

(2011) M. Laplante et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms Underlying Inflammation in Neurodegeneration

(2010) Christopher K. Glass et al.   CELL

A Proteasome Inhibitor, Bortezomib, Inhibits Breast Cancer Growth and Reduces Osteolysis by Downregulating Metastatic Genes

(2010) M. D. Jones et al.   CLINICAL CANCER RESEARCH

Proteasome inhibitor up regulates liver antioxidative enzymes in rat model of alcoholic liver disease

(2010) Fawzia Bardag-Gorce et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Prevention of Experimental Colitis by a Selective Inhibitor of the Immunoproteasome

(2010) M. Basler et al.   JOURNAL OF IMMUNOLOGY

Pivotal Role of TLR4 Receptors in Alcohol-Induced Neuroinflammation and Brain Damage

(2010) S. Alfonso-Loeches et al.   JOURNAL OF NEUROSCIENCE

The elimination of accumulated and aggregated proteins: A role for aggrephagy in neurodegeneration

(2010) Ai Yamamoto et al.   NEUROBIOLOGY OF DISEASE

Chaperone-mediated autophagy dysfunction in the pathogenesis of neurodegeneration

(2010) Hiroshi Koga et al.   NEUROBIOLOGY OF DISEASE

Regulation of Mammalian Autophagy in Physiology and Pathophysiology

(2010) Brinda Ravikumar et al.   PHYSIOLOGICAL REVIEWS

Chronic Ethanol Exposure Alters the Levels, Assembly, and Cellular Organization of the Actin Cytoskeleton and Microtubules in Hippocampal Neurons in Primary Culture

(2010) Ana M. Romero et al.   TOXICOLOGICAL SCIENCES

Critical Role of TLR4 Response in the Activation of Microglia Induced by Ethanol

(2009) S. Fernandez-Lizarbe et al.   JOURNAL OF IMMUNOLOGY

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

(2009) Tony Muchamuel et al.   NATURE MEDICINE

Review: Autophagy in neurodegeneration: firefighter and/or incendiarist?

(2009) A. Rami   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Autophagy: Principles and significance in health and disease

(2008) Virginia Todde et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dysfunction of the ubiquitin-proteasome system in multiple disease conditions: therapeutic approaches

(2008) Subhankar Paul   BIOESSAYS

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging

(2008) R. I. Morimoto   GENES & DEVELOPMENT

The persisting challenge of selective and specific proteasome inhibition

(2008) Michael Groll et al.   JOURNAL OF PEPTIDE SCIENCE

Small molecule enhancers of autophagy for neurodegenerative diseases

(2008) Sovan Sarkar et al.   Molecular BioSystems

Regulation of macroautophagy by mTOR and Beclin 1 complexes

(2007) Sophie Pattingre et al.   BIOCHIMIE

Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages

(2007) Sara Fernandez-Lizarbe et al.   MOLECULAR IMMUNOLOGY