Histone methyltransferase activity affects metabolism in human cells independently of transcriptional regulation

Transcription factor protein interactomes reveal genetic determinants in heart disease

(2022) Barbara Gonzalez-Teran et al.   CELL

Real age prediction from the transcriptome with RAPToR

(2022) Romain Bulteau et al.   NATURE METHODS

The impact of species-wide gene expression variation on Caenorhabditis elegans complex traits

(2022) Gaotian Zhang et al.   Nature Communications

Npac Is a Co-factor of Histone H3K36me3 and Regulates Transcriptional Elongation in Mouse Embryonic Stem Cells

(2021) Sue Yu et al.   GENOMICS PROTEOMICS & BIOINFORMATICS

Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

(2021) Gabriel K. Griffin et al.   NATURE

Sequence deeper without sequencing more: Bayesian resolution of ambiguously mapped reads

(2021) Rohan N. Shah et al.   PLoS Computational Biology

DREAM represses distinct targets by cooperating with different THAP domain proteins

(2021) Csenge Gal et al.   Cell Reports

Quantitative Proteomics of the Cancer Cell Line Encyclopedia

(2020) David P. Nusinow et al.   CELL

Nicotinamide N-methyltransferase overexpression may be associated with poor prognosis in ovarian cancer

(2020) İsmail Harmankaya et al.   JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Chromatin replication and epigenetic cell memory

(2020) Kathleen R. Stewart-Morgan et al.   NATURE CELL BIOLOGY

Reevaluating the roles of histone-modifying enzymes and their associated chromatin modifications in transcriptional regulation

(2020) Marc A. J. Morgan et al.   NATURE GENETICS

S-adenosyl-l-homocysteine hydrolase links methionine metabolism to the circadian clock and chromatin remodeling

(2020) Carolina Magdalen Greco et al.   Science Advances

Chromatin capture links the metabolic enzyme AHCY to stem cell proliferation

(2019) Sergi Aranda et al.   Science Advances

Histone methyltransferase SETDB1 contributes to melanoma tumorigenesis and serves as a new potential therapeutic target

(2019) Elias Orouji et al.   INTERNATIONAL JOURNAL OF CANCER

Proteomics reveals NNMT as a master metabolic regulator of cancer-associated fibroblasts

(2019) Mark A. Eckert et al.   NATURE

The landscape of cancer cell line metabolism

(2019) Haoxin Li et al.   NATURE MEDICINE

Benchmark and integration of resources for the estimation of human transcription factor activities

(2019) Luz Garcia-Alonso et al.   GENOME RESEARCH

Telescope: Characterization of the retrotranscriptome by accurate estimation of transposable element expression

(2019) Matthew L. Bendall et al.   PLoS Computational Biology

Transsulfuration Activity Can Support Cell Growth upon Extracellular Cysteine Limitation

(2019) Jiajun Zhu et al.   Cell Metabolism

S -adenosylhomocysteine Hydrolase Participates in DNA Methylation Inheritance

(2018) V.K. Chaithanya Ponnaluri et al.   JOURNAL OF MOLECULAR BIOLOGY

Sink into the Epigenome: Histones as Repositories That Influence Cellular Metabolism

(2018) Cunqi Ye et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Accurate Recycling of Parental Histones Reproduces the Histone Modification Landscape during DNA Replication

(2018) Nazaret Reverón-Gómez et al.   MOLECULAR CELL

Knock-down of AHCY and depletion of adenosine induces DNA damage and cell cycle arrest

(2018) Lucija Belužić et al.   Scientific Reports

Structure and function of archaeal histones

(2018) Bram Henneman et al.   PLoS Genetics

Mutations in S-adenosylhomocysteine hydrolase (AHCY) affect its nucleocytoplasmic distribution and capability to interact with S-adenosylhomocysteine hydrolase-like 1 protein

(2017) Ivana Grbeša et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The human protein atlas: A spatial map of the human proteome

(2017) Peter J. Thul et al.   PROTEIN SCIENCE

Nicotinamide N -Methyltransferase: More Than a Vitamin B3 Clearance Enzyme

(2017) Pavlos Pissios   TRENDS IN ENDOCRINOLOGY AND METABOLISM

RNA sequencing-based cell proliferation analysis across 19 cancers identifies a subset of proliferation-informative cancers with a common survival signature

(2017) Ryne C. Ramaker et al.   Oncotarget

Loss of the Caenorhabditis elegans pocket protein LIN-35 reveals MuvB's innate function as the repressor of DREAM target genes

(2017) Paul D. Goetsch et al.   PLoS Genetics

Is H3K4me3 instructive for transcription activation?

(2016) Françoise S. Howe et al.   BIOESSAYS

The harmonizome: a collection of processed datasets gathered to serve and mine knowledge about genes and proteins

(2016) Andrew D. Rouillard et al.   Database-The Journal of Biological Databases and Curation

The DREAM complex promotes gene body H2A.Z for target repression

(2015) Isabel Latorre et al.   GENES & DEVELOPMENT

The metabolome regulates the epigenetic landscape during naive-to-primed human embryonic stem cell transition

(2015) Henrik Sperber et al.   NATURE CELL BIOLOGY

TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data

(2015) Antonio Colaprico et al.   NUCLEIC ACIDS RESEARCH

Mapping and analysis of Caenorhabditis elegans transcription factor sequence specificities

(2015) Kamesh Narasimhan et al.   eLife

Determination and Inference of Eukaryotic Transcription Factor Sequence Specificity

(2014) Matthew T. Weirauch et al.   CELL

Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity

(2014) Daniel Kraus et al.   NATURE

deepTools: a flexible platform for exploring deep-sequencing data

(2014) Fidel Ramírez et al.   NUCLEIC ACIDS RESEARCH

Nicotinamide N-methyltransferase is overexpressed in prostate cancer and correlates with prolonged progression-free and overall survival times

(2014) WEIMIN ZHOU et al.   Oncology Letters

NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

(2013) Olesya A Ulanovskaya et al.   Nature Chemical Biology

Fast gapped-read alignment with Bowtie 2

(2012) Ben Langmead et al.   NATURE METHODS

Histone methylation: a dynamic mark in health, disease and inheritance

(2012) Eric L. Greer et al.   NATURE REVIEWS GENETICS

Understanding the language of Lys36 methylation at histone H3

(2012) Eric J. Wagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

(2011) Craig J. Ceol et al.   NATURE

Genome-wide association study identifies a new melanoma susceptibility locus at 1q21.3

(2011) Stuart MacGregor et al.   NATURE GENETICS

Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases

(2010) Nima Mosammaparast et al.   Annual Review of Biochemistry

Nicotinamide N -methyltransferase induces cellular invasion through activating matrix metalloproteinase-2 expression in clear cell renal cell carcinoma cells

(2010) Sai-Wen Tang et al.   CARCINOGENESIS

Specificity and rate of human and mouse liver and plasma phosphatidylcholine synthesis analyzed in vivo

(2010) Christopher J. Pynn et al.   JOURNAL OF LIPID RESEARCH

Serum levels of nicotinamide N-methyltransferase in patients with lung cancer

(2009) Mikio Tomida et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Overlapping gene expression profiles of cell migration and tumor invasion in human bladder cancer identify metallothionein 1E and nicotinamide N-methyltransferase as novel regulators of cell migration

(2008) Y Wu et al.   ONCOGENE

E2F – at the crossroads of life and death

(2008) Shirley Polager et al.   TRENDS IN CELL BIOLOGY

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY