Epigenetic silencing by SETDB1 suppresses tumour intrinsic immunogenicity

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Interplay of somatic alterations and immune infiltration modulates response to PD-1 blockade in advanced clear cell renal cell carcinoma

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NetMHCpan-4.1 and NetMHCIIpan-4.0: improved predictions of MHC antigen presentation by concurrent motif deconvolution and integration of MS MHC eluted ligand data

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Epigenetic therapy induces transcription of inverted SINEs and ADAR1 dependency

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A discriminative learning approach to differential expression analysis for single-cell RNA-seq

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The Histone Methyltransferase SETDB1 Controls T Helper Cell Lineage Integrity by Repressing Endogenous Retroviruses

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An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

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The emerging role of epigenetic therapeutics in immuno-oncology

(2019) Michael J. Topper et al.   Nature Reviews Clinical Oncology

In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma

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A large peptidome dataset improves HLA class I epitope prediction across most of the human population

(2019) Siranush Sarkizova et al.   NATURE BIOTECHNOLOGY

LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade

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Integrating single-cell transcriptomic data across different conditions, technologies, and species

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Reproducible workflow for multiplexed deep-scale proteome and phosphoproteome analysis of tumor tissues by liquid chromatography–mass spectrometry

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Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma

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The hallmarks of successful anticancer immunotherapy

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Fundamental Mechanisms of Immune Checkpoint Blockade Therapy

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PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools

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The Gene Ontology Resource: 20 years and still GOing strong

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Noncoding regions are the main source of targetable tumor-specific antigens

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Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction

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­­­Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia­­

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In vivo CRISPR screening identifies Ptpn2 as a cancer immunotherapy target

(2017) Robert T. Manguso et al.   NATURE

The methyltransferase SETDB1 regulates a large neuron-specific topological chromatin domain

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The Encyclopedia of DNA elements (ENCODE): data portal update

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Coinhibitory Pathways in Immunotherapy for Cancer

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Human adaptation and evolution by segmental duplication

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A Multiplexed System for Quantitative Comparisons of Chromatin Landscapes

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gEVE: a genome-based endogenous viral element database provides comprehensive viral protein-coding sequences in mammalian genomes

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Chromatin architecture reorganization during stem cell differentiation

(2015) Jesse R. Dixon et al.   NATURE

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

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Epigenetic silencing by the HUSH complex mediates position-effect variegation in human cells

(2015) I. A. Tchasovnikarova et al.   SCIENCE

The Molecular Signatures Database Hallmark Gene Set Collection

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An evolutionary arms race between KRAB zinc-finger genes ZNF91/93 and SVA/L1 retrotransposons

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Rational design of highly active sgRNAs for CRISPR-Cas9–mediated gene inactivation

(2014) John G Doench et al.   NATURE BIOTECHNOLOGY

Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position

(2013) Jason D Buenrostro et al.   NATURE METHODS

An integrated encyclopedia of DNA elements in the human genome

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The histone methyltransferase SETDB1 is recurrently amplified in melanoma and accelerates its onset

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Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

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KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Proviral silencing in embryonic stem cells requires the histone methyltransferase ESET

(2010) Toshiyuki Matsui et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

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Comprehensive Mapping of Long-Range Interactions Reveals Folding Principles of the Human Genome

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Regression of human kidney cancer following allogeneic stem cell transplantation is associated with recognition of an HERV-E antigen by T cells

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