Transcription factor protein interactomes reveal genetic determinants in heart disease
出版年份 2022 全文链接
标题
Transcription factor protein interactomes reveal genetic determinants in heart disease
作者
关键词
-
出版物
CELL
Volume -, Issue -, Pages -
出版商
Elsevier BV
发表日期
2022-02-18
DOI
10.1016/j.cell.2022.01.021
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Integrated analysis of multimodal single-cell data
- (2021) Yuhan Hao et al. CELL
- A transcriptional switch governs fibroblast activation in heart disease
- (2021) Michael Alexanian et al. NATURE
- A novel TAB2 nonsense mutation (p.S149X) causing autosomal dominant congenital heart defects: a case report of a Chinese family
- (2020) Jia Chen et al. BMC Cardiovascular Disorders
- Mechanisms of tissue and cell-type specificity in heritable traits and diseases
- (2020) Idan Hekselman et al. NATURE REVIEWS GENETICS
- De novo variants in exomes of congenital heart disease patients identify risk genes and pathways
- (2020) Cigdem Sevim Bayrak et al. Genome Medicine
- The mutational constraint spectrum quantified from variation in 141,456 humans
- (2020) Konrad J. Karczewski et al. NATURE
- Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease
- (2020) Julien Bryois et al. NATURE GENETICS
- Genomic analyses implicate noncoding de novo variants in congenital heart disease
- (2020) Felix Richter et al. NATURE GENETICS
- BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes
- (2020) Arun Padmanabhan et al. CIRCULATION
- The BioGRID database: A comprehensive biomedical resource of curated protein, genetic and chemical interactions
- (2020) Rose Oughtred et al. PROTEIN SCIENCE
- Systems genetics analysis identifies calcium-signaling defects as novel cause of congenital heart disease
- (2020) Jose M. G. Izarzugaza et al. Genome Medicine
- Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome
- (2020) Jeanne L Theis et al. eLife
- Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease
- (2020) Irfan S. Kathiriya et al. DEVELOPMENTAL CELL
- Measuring intolerance to mutation in human genetics
- (2019) Zachary L. Fuller et al. NATURE GENETICS
- A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex
- (2019) Chiara Marabelli et al. Cell Reports
- Single-cell analysis of cardiogenesis reveals basis for organ-level developmental defects
- (2019) T. Yvanka de Soysa et al. NATURE
- Oligogenic inheritance of a human heart disease involving a genetic modifier
- (2019) Casey A. Gifford et al. SCIENCE
- Impact of Mutations on NPAC Structural Dynamics: Mechanistic Insights from MD Simulations
- (2019) Marco Montefiori et al. Journal of Chemical Information and Modeling
- Fast, sensitive and accurate integration of single-cell data with Harmony
- (2019) Ilya Korsunsky et al. NATURE METHODS
- A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers
- (2019) Brynn N. Akerberg et al. Nature Communications
- Splice-Junction-Based Mapping of Alternative Isoforms in the Human Proteome
- (2019) Edward Lau et al. Cell Reports
- The Human Transcription Factors
- (2018) Samuel A. Lambert et al. CELL
- NDF, a nucleosome-destabilizing factor that facilitates transcription through nucleosomes
- (2018) Jia Fei et al. GENES & DEVELOPMENT
- Genetic Basis for Congenital Heart Disease: Revisited: A Scientific Statement From the American Heart Association
- (2018) Mary Ella Pierpont et al. CIRCULATION
- The PRIDE database and related tools and resources in 2019: improving support for quantification data
- (2018) Yasset Perez-Riverol et al. NUCLEIC ACIDS RESEARCH
- STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
- (2018) Damian Szklarczyk et al. NUCLEIC ACIDS RESEARCH
- CADD: predicting the deleteriousness of variants throughout the human genome
- (2018) Philipp Rentzsch et al. NUCLEIC ACIDS RESEARCH
- A clinically driven variant prioritization framework outperforms purely computational approaches for the diagnostic analysis of singleton WES data
- (2017) Zornitza Stark et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- GATA4 loss of function in liver cancer impedes precursor to hepatocyte transition
- (2017) Francis O. Enane et al. JOURNAL OF CLINICAL INVESTIGATION
- Genetic effects on gene expression across human tissues
- (2017) François Aguet et al. NATURE
- Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
- (2017) Sheng Chih Jin et al. NATURE GENETICS
- Settling the score: variant prioritization and Mendelian disease
- (2017) Karen Eilbeck et al. NATURE REVIEWS GENETICS
- Disease Model of GATA4 Mutation Reveals Transcription Factor Cooperativity in Human Cardiogenesis
- (2016) Yen-Sin Ang et al. CELL
- Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis
- (2016) Luis Luna-Zurita et al. CELL
- ATP-dependent chromatin remodeling during mammalian development
- (2016) Swetansu K. Hota et al. DEVELOPMENT
- The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation
- (2016) Lauren Waldron et al. DEVELOPMENTAL CELL
- Distinct genetic architectures for syndromic and nonsyndromic congenital heart defects identified by exome sequencing
- (2016) Alejandro Sifrim et al. NATURE GENETICS
- Human induced pluripotent stem cell–derived cardiomyocytes recapitulate the predilection of breast cancer patients to doxorubicin-induced cardiotoxicity
- (2016) Paul W Burridge et al. NATURE MEDICINE
- deepTools2: a next generation web server for deep-sequencing data analysis
- (2016) Fidel Ramírez et al. NUCLEIC ACIDS RESEARCH
- SAINTq: Scoring protein-protein interactions in affinity purification - mass spectrometry experiments with fragment or peptide intensity data
- (2016) Guoci Teo et al. PROTEOMICS
- p38γ and δ promote heart hypertrophy by targeting the mTOR-inhibitory protein DEPTOR for degradation
- (2016) Bárbara González-Terán et al. Nature Communications
- De Novo and Rare Variants at Multiple Loci Support the Oligogenic Origins of Atrioventricular Septal Heart Defects
- (2016) James R. Priest et al. PLoS Genetics
- PRROC: computing and visualizing precision-recall and receiver operating characteristic curves in R
- (2015) Jan Grau et al. BIOINFORMATICS
- Understanding multicellular function and disease with human tissue-specific networks
- (2015) Casey S Greene et al. NATURE GENETICS
- Tissue-based map of the human proteome
- (2015) M. Uhlen et al. SCIENCE
- De novo mutations in congenital heart disease with neurodevelopmental and other congenital anomalies
- (2015) J. Homsy et al. SCIENCE
- Sequential Binding of MEIS1 and NKX2-5 on the Popdc2 Gene: A Mechanism for Spatiotemporal Regulation of Enhancers during Cardiogenesis
- (2015) Laurent Dupays et al. Cell Reports
- A Non-invasive Platform for Functional Characterization of Stem-Cell-Derived Cardiomyocytes with Applications in Cardiotoxicity Testing
- (2015) Mahnaz Maddah et al. Stem Cell Reports
- Structural characterization of a β-hydroxyacid dehydrogenase from Geobacter sulfurreducens and Geobacter metallireducens with succinic semialdehyde reductase activity
- (2014) Yanfeng Zhang et al. BIOCHIMIE
- A Bayesian framework for de novo mutation calling in parents-offspring trios
- (2014) Qiang Wei et al. BIOINFORMATICS
- Enhanced utility of family-centered diagnostic exome sequencing with inheritance model–based analysis: results from 500 unselected families with undiagnosed genetic conditions
- (2014) Kelly D. Farwell et al. GENETICS IN MEDICINE
- Large-scale discovery of novel genetic causes of developmental disorders
- (2014) T. W. Fitzgerald et al. NATURE
- A framework for the interpretation of de novo mutation in human disease
- (2014) Kaitlin E Samocha et al. NATURE GENETICS
- Isolation of single-base genome-edited human iPS cells without antibiotic selection
- (2014) Yuichiro Miyaoka et al. NATURE METHODS
- Comparative Analysis of Human Tissue Interactomes Reveals Factors Leading to Tissue-Specific Manifestation of Hereditary Diseases
- (2014) Ruth Barshir et al. PLoS Computational Biology
- featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
- (2013) Y. Liao et al. BIOINFORMATICS
- Mouse Tenm4 is required for mesoderm induction
- (2013) Hisashi Nakamura et al. BMC DEVELOPMENTAL BIOLOGY
- Recessive TTN truncating mutations define novel forms of core myopathy with heart disease
- (2013) C. Chauveau et al. HUMAN MOLECULAR GENETICS
- CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice
- (2013) Yuelong Liu et al. HUMAN MOLECULAR GENETICS
- Protein and ligand preparation: parameters, protocols, and influence on virtual screening enrichments
- (2013) G. Madhavi Sastry et al. JOURNAL OF COMPUTER-AIDED MOLECULAR DESIGN
- Histone modifications for human epigenome analysis
- (2013) Hiroshi Kimura JOURNAL OF HUMAN GENETICS
- De novo mutations in histone-modifying genes in congenital heart disease
- (2013) Samir Zaidi et al. NATURE
- De Novo Mutations in MLL Cause Wiedemann-Steiner Syndrome
- (2012) Wendy D. Jones et al. AMERICAN JOURNAL OF HUMAN GENETICS
- RSeQC: quality control of RNA-seq experiments
- (2012) Liguo Wang et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Distinct Metabolic Flow Enables Large-Scale Purification of Mouse and Human Pluripotent Stem Cell-Derived Cardiomyocytes
- (2012) Shugo Tohyama et al. Cell Stem Cell
- LSD2/KDM1B and Its Cofactor NPAC/GLYR1 Endow a Structural and Molecular Model for Regulation of H3K4 Demethylation
- (2012) Rui Fang et al. MOLECULAR CELL
- Fast gapped-read alignment with Bowtie 2
- (2012) Ben Langmead et al. NATURE METHODS
- Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions
- (2012) Xiaojun Lian et al. Nature Protocols
- NCBI GEO: archive for functional genomics data sets—update
- (2012) Tanya Barrett et al. NUCLEIC ACIDS RESEARCH
- Genome-Wide Localization of Protein-DNA Binding and Histone Modification by a Bayesian Change-Point Method with ChIP-seq Data
- (2012) Haipeng Xing et al. PLoS Computational Biology
- High Resolution Genome Wide Binding Event Finding and Motif Discovery Reveals Transcription Factor Spatial Binding Constraints
- (2012) Yuchun Guo et al. PLoS Computational Biology
- Enhancing the Prioritization of Disease-Causing Genes through Tissue Specific Protein Interaction Networks
- (2012) Oded Magger et al. PLoS Computational Biology
- The Brd4 Extraterminal Domain Confers Transcription Activation Independent of pTEFb by Recruiting Multiple Proteins, Including NSD3
- (2011) S. Rahman et al. MOLECULAR AND CELLULAR BIOLOGY
- Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development
- (2011) I. P. Moskowitz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Haploinsufficiency of TAB2 Causes Congenital Heart Defects in Humans
- (2010) Bernard Thienpont et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
- (2010) K. Wang et al. NUCLEIC ACIDS RESEARCH
- Identification of GATA6 Sequence Variants in Patients With Congenital Heart Defects
- (2010) Meenakshi Maitra et al. PEDIATRIC RESEARCH
- Characterising and Predicting Haploinsufficiency in the Human Genome
- (2010) Ni Huang et al. PLoS Genetics
- A scaling normalization method for differential expression analysis of RNA-seq data
- (2010) Mark D Robinson et al. GENOME BIOLOGY
- edgeR: a Bioconductor package for differential expression analysis of digital gene expression data
- (2009) M. D. Robinson et al. BIOINFORMATICS
- Walking the Interactome for Prioritization of Candidate Disease Genes
- (2008) Sebastian Köhler et al. AMERICAN JOURNAL OF HUMAN GENETICS
- iRefIndex: A consolidated protein interaction database with provenance
- (2008) Sabry Razick et al. BMC BIOINFORMATICS
- Interaction of Gata4 and Gata6 with Tbx5 is critical for normal cardiac development
- (2008) Meenakshi Maitra et al. DEVELOPMENTAL BIOLOGY
- MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification
- (2008) Jürgen Cox et al. NATURE BIOTECHNOLOGY
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