The effects of branched-chain amino acids on muscle protein synthesis, muscle protein breakdown and associated molecular signalling responses in humans: an update
出版年份 2023 全文链接
标题
The effects of branched-chain amino acids on muscle protein synthesis, muscle protein breakdown and associated molecular signalling responses in humans: an update
作者
关键词
-
出版物
NUTRITION RESEARCH REVIEWS
Volume -, Issue -, Pages 1-14
出版商
Cambridge University Press (CUP)
发表日期
2023-09-08
DOI
10.1017/s0954422423000197
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Co-Ingestion of Branched-Chain Amino Acids and Carbohydrate Stimulates Myofibrillar Protein Synthesis Following Resistance Exercise in Trained Young Men
- (2023) Sarah R. Jackman et al. INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM
- The skeletal muscle fiber periphery: A nexus of mTOR-related anabolism
- (2022) Cassidy T. Tinline-Goodfellow et al. Sports Medicine and Health Science
- Assessing the whole-body protein synthetic response to feeding in vivo in human subjects
- (2021) Jorn Trommelen et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Dileucine ingestion is more effective than leucine in stimulating muscle protein turnover in young males: a double blind randomized controlled trial
- (2021) Kevin J.M. Paulussen et al. JOURNAL OF APPLIED PHYSIOLOGY
- Ingestion of Free Amino Acids Compared with an Equivalent Amount of Intact Protein Results in More Rapid Amino Acid Absorption and Greater Postprandial Plasma Amino Acid Availability Without Affecting Muscle Protein Synthesis Rates in Young Adults in a Double-Blind Randomized Trial
- (2021) Michelle E G Weijzen et al. JOURNAL OF NUTRITION
- Prevalence of dietary supplement use by gym members in Portugal and associated factors
- (2020) João Ruano et al. Journal of the International Society of Sports Nutrition
- mTOR at the nexus of nutrition, growth, ageing and disease
- (2020) Grace Y. Liu et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Leucine-enriched amino acids maintain peripheral mTOR-Rheb localization independent of myofibrillar protein synthesis and mTORC1 signaling postexercise
- (2020) Sarkis J. Hannaian et al. JOURNAL OF APPLIED PHYSIOLOGY
- Protein‐carbohydrate ingestion alters Vps34 cellular localization independent of changes in kinase activity in human skeletal muscle
- (2020) Nathan Hodson et al. EXPERIMENTAL PHYSIOLOGY
- Branched-Chain Amino Acid Fortification Does Not Restore Muscle Protein Synthesis Rates following Ingestion of Lower- Compared with Higher-Dose Mycoprotein
- (2020) Alistair J Monteyne et al. JOURNAL OF NUTRITION
- The Muscle Protein Synthetic Response to Meal Ingestion Following Resistance-Type Exercise
- (2019) Jorn Trommelen et al. SPORTS MEDICINE
- Branched-chain amino acid and branched-chain ketoacid ingestion increases muscle protein synthesis rates in vivo in older adults: a double-blind, randomized trial
- (2019) Cas J Fuchs et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- MOLECULAR REGULATION OF HUMAN SKELETAL MUSCLE PROTEIN SYNTHESIS IN RESPONSE TO EXERCISE AND NUTRIENTS: A COMPASS FOR OVERCOMING AGE-RELATED ANABOLIC RESISTANCE
- (2019) Nathan Hodson et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Time-dependent regulation of postprandial muscle protein synthesis rates after milk protein ingestion in young men
- (2019) Stephan van Vliet et al. JOURNAL OF APPLIED PHYSIOLOGY
- Protein Intake to Maximize Whole-Body Anabolism during Postexercise Recovery in Resistance-Trained Men with High Habitual Intakes is Severalfold Greater than the Current Recommended Dietary Allowance
- (2019) Michael Mazzulla et al. JOURNAL OF NUTRITION
- Protein leucine content is a determinant of shorter- and longer-term muscle protein synthetic responses at rest and following resistance exercise in healthy older women: a randomized, controlled trial
- (2018) Michaela C Devries et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Potential Role of MicroRNA in the Anabolic Capacity of Skeletal Muscle with Aging
- (2018) Lee M. Margolis et al. EXERCISE AND SPORT SCIENCES REVIEWS
- Pronounced energy restriction with elevated protein intake results in no change in proteolysis and reductions in skeletal muscle protein synthesis that are mitigated by resistance exercise
- (2018) Amy J. Hector et al. FASEB JOURNAL
- Rapamycin-insensitive mechanistic target of rapamycin regulates basal and resistance exercise–induced muscle protein synthesis
- (2018) Riki Ogasawara et al. FASEB JOURNAL
- Branched-Chain Amino Acids Are the Primary Limiting Amino Acids in the Diets of Endurance-Trained Men after a Bout of Prolonged Exercise
- (2018) Hiroyuki Kato et al. JOURNAL OF NUTRITION
- Leucine, Not Total Protein, Content of a Supplement Is the Primary Determinant of Muscle Protein Anabolic Responses in Healthy Older Women
- (2018) Michaela C Devries et al. JOURNAL OF NUTRITION
- Assessing the Role of Muscle Protein Breakdown in Response to Nutrition and Exercise in Humans
- (2018) Kevin D. Tipton et al. SPORTS MEDICINE
- Indicator Amino Acid Oxidation: Concept and Application
- (2018) Rajavel Elango et al. JOURNAL OF NUTRITION
- The muscle anabolic effect of protein ingestion during a hyperinsulinaemic euglycaemic clamp in middle-aged women is not caused by leucine alone
- (2018) Stephan van Vliet et al. JOURNAL OF PHYSIOLOGY-LONDON
- Branched Chain Amino Acids
- (2018) Michael Neinast et al. Annual Review of Physiology
- The Importance of mTOR Trafficking for Human Skeletal Muscle Translational Control
- (2018) Nathan Hodson et al. EXERCISE AND SPORT SCIENCES REVIEWS
- The role of raptor in the mechanical load-induced regulation of mTOR signaling, protein synthesis, and skeletal muscle hypertrophy
- (2018) Jae-Sung You et al. FASEB JOURNAL
- Protein to Maximize Whole-Body Anabolism in Resistance-trained Females after Exercise
- (2018) Julia M. Malowany et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Recent Advances in the Characterization of Skeletal Muscle and Whole-Body Protein Responses to Dietary Protein and Exercise during Negative Energy Balance
- (2018) John W Carbone et al. Advances in Nutrition
- Branched-chain amino acids and muscle protein synthesis in humans: myth or reality?
- (2017) Robert R. Wolfe Journal of the International Society of Sports Nutrition
- Increased Protein Requirements in Female Athletes after Variable-Intensity Exercise
- (2017) DENISE J. WOODING et al. MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
- Molecular Regulation of Exercise-Induced Muscle Fiber Hypertrophy
- (2017) Marcas M. Bamman et al. Cold Spring Harbor Perspectives in Medicine
- Skeletal Muscle myomiR Are Differentially Expressed by Endurance Exercise Mode and Combined Essential Amino Acid and Carbohydrate Supplementation
- (2017) Lee M. Margolis et al. Frontiers in Physiology
- Branched-Chain Amino Acid Ingestion Stimulates Muscle Myofibrillar Protein Synthesis following Resistance Exercise in Humans
- (2017) Sarah R. Jackman et al. Frontiers in Physiology
- Leucine supplementation enhances integrative myofibrillar protein synthesis in free-living older men consuming lower- and higher-protein diets: a parallel-group crossover study
- (2016) Caoileann H Murphy et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise
- (2016) Marcus Moberg et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Insulin does not stimulate muscle protein synthesis during increased plasma branched-chain amino acids alone but still decreases whole body proteolysis in humans
- (2016) Sarah Everman et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Branched-chain amino acids administration suppresses endurance exercise-related activation of ubiquitin proteasome signaling in trained human skeletal muscle
- (2016) Evgeny A. Lysenko et al. Journal of Physiological Sciences
- Selective Modulation of MicroRNA Expression with Protein Ingestion Following Concurrent Resistance and Endurance Exercise in Human Skeletal Muscle
- (2016) Donny M. Camera et al. Frontiers in Physiology
- Protein Requirements Are Elevated in Endurance Athletes after Exercise as Determined by the Indicator Amino Acid Oxidation Method
- (2016) Hiroyuki Kato et al. PLoS One
- The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise
- (2016) Riki Ogasawara et al. Scientific Reports
- The effectiveness of leucine on muscle protein synthesis, lean body mass and leg lean mass accretion in older people: a systematic review and meta-analysis
- (2015) Zhe-rong Xu et al. BRITISH JOURNAL OF NUTRITION
- Role of insulin in the regulation of human skeletal muscle protein synthesis and breakdown: a systematic review and meta-analysis
- (2015) Haitham Abdulla et al. DIABETOLOGIA
- Rapamycin does not prevent increases in myofibrillar or mitochondrial protein synthesis following endurance exercise
- (2015) Andrew Philp et al. JOURNAL OF PHYSIOLOGY-LONDON
- Acute resistance exercise activates rapamycin-sensitive and -insensitive mechanisms that control translational activity and capacity in skeletal muscle
- (2015) Daniel W. D. West et al. JOURNAL OF PHYSIOLOGY-LONDON
- Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
- (2015) R. A. Saxton et al. SCIENCE
- Sestrin2 is a leucine sensor for the mTORC1 pathway
- (2015) R. L. Wolfson et al. SCIENCE
- Reduced resting skeletal muscle protein synthesis is rescued by resistance exercise and protein ingestion following short-term energy deficit
- (2014) José L. Areta et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Effects of short-term energy deficit on muscle protein breakdown and intramuscular proteolysis in normal-weight young adults
- (2014) John W. Carbone et al. Applied Physiology Nutrition and Metabolism
- Beyond muscle hypertrophy: why dietary protein is important for endurance athletes
- (2014) Daniel R. Moore et al. Applied Physiology Nutrition and Metabolism
- The Molecular Basis for Load-Induced Skeletal Muscle Hypertrophy
- (2014) George R. Marcotte et al. CALCIFIED TISSUE INTERNATIONAL
- Leucine as a treatment for muscle wasting: A critical review
- (2014) Daniel J. Ham et al. CLINICAL NUTRITION
- Assessment of skeletal muscle proteolysis and the regulatory response to nutrition and exercise
- (2014) Stefan M. Pasiakos et al. IUBMB LIFE
- Influence of divergent exercise contraction mode and whey protein supplementation on atrogin-1, MuRF1, and FOXO1/3A in human skeletal muscle
- (2014) Renae J. Stefanetti et al. JOURNAL OF APPLIED PHYSIOLOGY
- Where is mTOR and what is it doing there?
- (2014) Charles Betz et al. JOURNAL OF CELL BIOLOGY
- Whey Protein Supplementation Preserves Postprandial Myofibrillar Protein Synthesis during Short-Term Energy Restriction in Overweight and Obese Adults
- (2014) Amy J Hector et al. JOURNAL OF NUTRITION
- Periexercise coingestion of branched-chain amino acids and carbohydrate in men does not preferentially augment resistance exercise–induced increases in phosphatidylinositol 3 kinase/protein kinase B–mammalian target of rapamycin pathway markers indicative of muscle protein synthesis
- (2014) Maria Pontes Ferreira et al. NUTRITION RESEARCH
- Bolus ingestion of individual branched-chain amino acids alters plasma amino acid profiles in young healthy men
- (2014) Takuya Matsumoto et al. SpringerPlus
- Role of amino acid transporters in amino acid sensing
- (2013) Peter M Taylor AMERICAN JOURNAL OF CLINICAL NUTRITION
- Myofibrillar muscle protein synthesis rates subsequent to a meal in response to increasing doses of whey protein at rest and after resistance exercise
- (2013) Oliver C Witard et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial
- (2013) Tyler A Churchward-Venne et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Amino acid transporters in the regulation of human skeletal muscle protein metabolism
- (2013) Jared M. Dickinson et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Positive muscle protein net balance and differential regulation of atrogene expression after resistance exercise and milk protein supplementation
- (2013) Søren Reitelseder et al. EUROPEAN JOURNAL OF NUTRITION
- Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats
- (2013) Li Luo et al. EXPERIMENTAL GERONTOLOGY
- Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome
- (2013) Marco Sandri INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism
- (2013) D. J. Wilkinson et al. JOURNAL OF PHYSIOLOGY-LONDON
- The time course of the adaptations of human muscle proteome to bed rest and the underlying mechanisms
- (2012) Lorenza Brocca et al. JOURNAL OF PHYSIOLOGY-LONDON
- Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men
- (2012) Tyler A. Churchward-Venne et al. JOURNAL OF PHYSIOLOGY-LONDON
- Muscle protein synthesis in response to nutrition and exercise
- (2012) P. J. Atherton et al. JOURNAL OF PHYSIOLOGY-LONDON
- Intake of branched-chain amino acids influences the levels of MAFbx mRNA and MuRF-1 total protein in resting and exercising human muscle
- (2011) Marcus Borgenvik et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Autophagy-related and autophagy-regulatory genes are induced in human muscle after ultraendurance exercise
- (2011) Cécile Jamart et al. EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY
- Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids
- (2011) Jared M. Dickinson et al. JOURNAL OF NUTRITION
- Enhanced Amino Acid Sensitivity of Myofibrillar Protein Synthesis Persists for up to 24 h after Resistance Exercise in Young Men
- (2011) Nicholas A. Burd et al. JOURNAL OF NUTRITION
- Effects of Branched-Chain Amino Acid Supplementation on Plasma Concentrations of Free Amino Acids, Insulin, and Energy Substrates in Young Men
- (2011) Yi ZHANG et al. JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY
- Lysosomal positioning coordinates cellular nutrient responses
- (2011) Viktor I. Korolchuk et al. NATURE CELL BIOLOGY
- Influence of supplementation with branched-chain amino acids in combination with resistance exercise on p70S6 kinase phosphorylation in resting and exercising human skeletal muscle
- (2010) W. Apró et al. Acta Physiologica
- Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling
- (2010) Philip J Atherton et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Muscle specific microRNAs are regulated by endurance exercise in human skeletal muscle
- (2010) Søren Nielsen et al. JOURNAL OF PHYSIOLOGY-LONDON
- Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia
- (2009) Emilie A Wilkes et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells
- (2009) Philip J. Atherton et al. AMINO ACIDS
- Amino acid requirements in humans: with a special emphasis on the metabolic availability of amino acids
- (2009) Rajavel Elango et al. AMINO ACIDS
- Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise
- (2009) Stephanie Eva Wohlgemuth et al. EXPERIMENTAL GERONTOLOGY
- Essential Amino Acids Increase MicroRNA-499, -208b, and -23a and Downregulate Myostatin and Myocyte Enhancer Factor 2C mRNA Expression in Human Skeletal Muscle
- (2009) Micah J. Drummond et al. JOURNAL OF NUTRITION
- Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis
- (2009) Micah J. Drummond et al. JOURNAL OF PHYSIOLOGY-LONDON
- Ingested protein dose response of muscle and albumin protein synthesis after resistance exercise in young men
- (2008) Daniel R Moore et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids
- (2008) Micah J. Drummond et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle
- (2008) P. L. Greenhaff et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Influence of leucine infusion on intracellular amino acids in humans
- (2008) A. ALVESTRAND et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Amino Acid Transport Across Mammalian Intestinal and Renal Epithelia
- (2008) Stefan Bröer PHYSIOLOGICAL REVIEWS
- The Rag GTPases Bind Raptor and Mediate Amino Acid Signaling to mTORC1
- (2008) Y. Sancak et al. SCIENCE
- Repeated resistance exercise training induces different changes in mRNA expression of MAFbx and MuRF-1 in human skeletal muscle
- (2007) Henrik Mascher et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
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