Activation of mTORC1 by leucine is potentiated by branched-chain amino acids and even more so by essential amino acids following resistance exercise

Leucine does not affect mechanistic target of rapamycin complex 1 assembly but is required for maximal ribosomal protein s6 kinase 1 activity in human skeletal muscle following resistance exercise

(2015) William Apró et al.   FASEB JOURNAL

Quantitative amino acid profiling and stable isotopically labeled amino acid tracer enrichment used for in vivo human systemic and tissue kinetics measurements

(2014) Andreas Bornø et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Determination of human muscle protein fractional synthesis rate: an evaluation of different mass spectrometry techniques and considerations for tracer choice

(2014) Andreas Bornø et al.   JOURNAL OF MASS SPECTROMETRY

Integration of signals generated by nutrients, hormones, and exercise in skeletal muscle

(2013) Scot R Kimball   AMERICAN JOURNAL OF CLINICAL NUTRITION

Leucine supplementation of a low-protein mixed macronutrient beverage enhances myofibrillar protein synthesis in young men: a double-blind, randomized trial

(2013) Tyler A Churchward-Venne et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Absence of leucine in an essential amino acid supplement reduces activation of mTORC1 signalling following resistance exercise in young females

(2013) Marcus Moberg et al.   Applied Physiology Nutrition and Metabolism

Addition of Carbohydrate or Alanine to an Essential Amino Acid Mixture Does Not Enhance Human Skeletal Muscle Protein Anabolism

(2013) Erin L. Glynn et al.   JOURNAL OF NUTRITION

Effects of leucine and its metabolite β-hydroxy-β-methylbutyrate on human skeletal muscle protein metabolism

(2013) D. J. Wilkinson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Leucyl-tRNA Synthetase Is an Intracellular Leucine Sensor for the mTORC1-Signaling Pathway

(2012) Jung Min Han et al.   CELL

Supplementation of a suboptimal protein dose with leucine or essential amino acids: effects on myofibrillar protein synthesis at rest and following resistance exercise in men

(2012) Tyler A. Churchward-Venne et al.   JOURNAL OF PHYSIOLOGY-LONDON

Intake of branched-chain amino acids influences the levels of MAFbx mRNA and MuRF-1 total protein in resting and exercising human muscle

(2011) Marcus Borgenvik et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms Involved in the Coordinate Regulation of mTORC1 by Insulin and Amino Acids

(2011) Michael D. Dennis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Target of Rapamycin Complex 1 Activation Is Required for the Stimulation of Human Skeletal Muscle Protein Synthesis by Essential Amino Acids

(2011) Jared M. Dickinson et al.   JOURNAL OF NUTRITION

“Semi-open” muscle biopsy technique A SIMPLE OUTPATIENT PROCEDURE

(2010) K. G. Henriksson   ACTA NEUROLOGICA SCANDINAVICA

Influence of supplementation with branched-chain amino acids in combination with resistance exercise on p70S6 kinase phosphorylation in resting and exercising human skeletal muscle

(2010) W. Apró et al.   Acta Physiologica

Muscle full effect after oral protein: time-dependent concordance and discordance between human muscle protein synthesis and mTORC1 signaling

(2010) Philip J Atherton et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Distinct anabolic signalling responses to amino acids in C2C12 skeletal muscle cells

(2009) Philip J. Atherton et al.   AMINO ACIDS

Stimulation of Muscle Protein Synthesis by Prolonged Parenteral Infusion of Leucine Is Dependent on Amino Acid Availability in Neonatal Pigs

(2009) Fiona A. Wilson et al.   JOURNAL OF NUTRITION

Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation

(2008) Agus Suryawan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle

(2008) P. L. Greenhaff et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men

(2008) Vinod Kumar et al.   JOURNAL OF PHYSIOLOGY-LONDON